Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(127 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
Show 10 more subcategories
Found 3923 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formula:C9H12N2O5SPurity:99.91%Color and Shape:SolidMolecular weight:260.27Fosifloxuridine nafalbenamide
CAS:Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.
Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56N6,N6-Dimethyladenosine
CAS:N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.Formula:C12H17N5O4Purity:98.79%Color and Shape:White PowderMolecular weight:295.29Dalpiciclib hydrochloride
Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.Formula:C25H31ClN6O2Color and Shape:SolidMolecular weight:483.01RKI-1447
CAS:RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Formula:C16H14N4O2SPurity:98% - 99.73%Color and Shape:SolidMolecular weight:326.37Ref: TM-T1898
5mg49.00€1mL*10mM (DMSO)54.00€10mg93.00€25mg177.00€50mg295.00€100mg391.00€200mg494.00€500mg797.00€Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73YKL-5-124
CAS:YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFormula:C28H33N7O3Purity:99.36%Color and Shape:SolidMolecular weight:515.61Ref: TM-T22461
1mg82.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg222.00€25mg385.00€50mg560.00€100mg790.00€GNF2133 hydrochloride
CAS:GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.Formula:C24H31ClN6O2Color and Shape:SolidMolecular weight:471.0MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg50.00€2mg67.00€5mg84.00€1mL*10mM (DMSO)88.00€10mg120.00€25mg220.00€50mg356.00€100mg537.00€NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formula:C17H19Cl2N5O4SPurity:99.56% - 99.85%Color and Shape:SolidMolecular weight:460.33Ref: TM-TQ0068
1mg46.00€5mg92.00€1mL*10mM (DMSO)94.00€10mg138.00€25mg255.00€50mg374.00€100mg533.00€200mg705.00€Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formula:C10H17N2O14P3·XNaPurity:99.78%Color and Shape:White Amorphous PowderMolecular weight:482.17（free base）TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formula:C9H2Cl4O2Purity:99.34%Color and Shape:SolidMolecular weight:283.92RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:373.83CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purity:99.58%Color and Shape:SolidMolecular weight:478.82Ref: TM-T22062
5mg35.00€1mL*10mM (DMSO)40.00€10mg54.00€25mg108.00€50mg178.00€100mg286.00€200mg425.00€Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formula:C27H32F2N8Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:506.59TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formula:C72H66N8O12S4Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:1363.6BMS-5
CAS:BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formula:C17H14Cl2F2N4OSPurity:98.01% - 99.88%Color and Shape:SolidMolecular weight:431.29Ref: TM-T4598
1mg40.00€2mg52.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg116.00€25mg188.00€50mg281.00€100mg420.00€2′-Deoxy-2′-fluoroguanosine
CAS:2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Formula:C10H12FN5O4Purity:99.89%Color and Shape:SolidMolecular weight:285.23Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purity:98%Color and Shape:SolidMolecular weight:596.64CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formula:C12H14N2OSPurity:96.50%Color and Shape:SolidMolecular weight:234.32NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurity:98.03% - 99.46%Color and Shape:SolidMolecular weight:433.48Ref: TM-T8886
1mg74.00€5mg170.00€1mL*10mM (DMSO)188.00€10mg274.00€25mg472.00€50mg655.00€100mg944.00€200mg1,264.00€Sarecycline free base
CAS:Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.Formula:C24H29N3O8Purity:98%Color and Shape:SolidMolecular weight:487.5Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purity:98.65% - 99.86%Color and Shape:SolidMolecular weight:500.6Ref: TM-T2077
5mg46.00€1mL*10mM (DMSO)49.00€10mg66.00€25mg81.00€50mg96.00€100mg110.00€200mg161.00€500mg260.00€LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.02THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purity:97.42% - 99.27%Color and Shape:SolidMolecular weight:566.05TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Ref: TM-T5310
1mg50.00€5mg99.00€1mL*10mM (DMSO)102.00€10mg152.00€25mg245.00€50mg353.00€100mg492.00€200mg700.00€Trimethoprim sulfate
CAS:Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.Formula:C28H38N8O10SColor and Shape:SolidMolecular weight:678.72SNS-314
CAS:SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.Formula:C18H15ClN6OS2Purity:98%Color and Shape:SolidMolecular weight:430.93CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formula:C14H12N6O2SPurity:99.54%Color and Shape:SolidMolecular weight:328.35Ref: TM-T9615
1mg50.00€5mg114.00€1mL*10mM (DMSO)126.00€10mg177.00€25mg356.00€50mg557.00€100mg858.00€200mg1,153.00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purity:98.26% - 99.85%Color and Shape:SolidMolecular weight:384.43Ref: TM-T3553
1mg34.00€2mg48.00€5mg70.00€1mL*10mM (DMSO)77.00€10mg109.00€25mg177.00€50mg263.00€100mg389.00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purity:98.68% - 99.77%Color and Shape:SolidMolecular weight:385.85Ref: TM-T4321
1mg34.00€2mg43.00€5mg63.00€1mL*10mM (DMSO)69.00€10mg88.00€25mg130.00€50mg198.00€100mg298.00€Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purity:99.64%Color and Shape:SolidMolecular weight:507.18Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.02% - 98.59%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg46.00€5mg73.00€10mg92.00€1mL*10mM (DMSO)93.00€25mg178.00€50mg295.00€100mg477.00€500mg1,018.00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.52Ref: TM-T6753
2mg38.00€5mg57.00€1mL*10mM (DMSO)84.00€10mg92.00€25mg160.00€50mg231.00€100mg343.00€200mg485.00€2-Aminofluorene
CAS:2-Aminofluorene (2-Fluorenamine) is a biochemical.Formula:C13H11NPurity:99.9%Color and Shape:Light Yellow CrystallineMolecular weight:181.23Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5524
1mg66.00€2mg89.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg401.00€50mg580.00€100mg797.00€200mg1,099.00€Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:543.61ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89Ref: TM-T1855
5mg52.00€10mg74.00€1mL*10mM (DMSO)74.00€25mg129.00€50mg210.00€100mg294.00€200mg470.00€500mg763.00€AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formula:C24H26F3N7O2Purity:99.59%Color and Shape:SolidMolecular weight:501.5Hydroxyfasudil
CAS:Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Formula:C14H17N3O3SPurity:98.13%Color and Shape:SolidMolecular weight:307.37ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36Ref: TM-T2670
2mg33.00€5mg47.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg135.00€50mg222.00€100mg331.00€200mg470.00€HQ461
CAS:HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Formula:C15H15N5OS2Purity:98.11%Color and Shape:SolidMolecular weight:345.44Ref: TM-T9849
1mg43.00€2mg56.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg144.00€25mg319.00€50mg537.00€100mg767.00€500mg1,558.00€CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formula:C27H27N7O2SPurity:95.44% - 99.4%Color and Shape:SolidMolecular weight:513.61AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formula:C21H17N3O2Purity:99.19%Color and Shape:SolidMolecular weight:343.38TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Formula:C13H13Cl3N4Color and Shape:SolidMolecular weight:331.63A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Ref: TM-T2254
2mg42.00€5mg50.00€1mL*10mM (DMSO)67.00€10mg77.00€25mg152.00€50mg258.00€100mg505.00€500mg1,108.00€HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formula:C28H27N3O3Color and Shape:SolidMolecular weight:453.53IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purity:98.26% - 99.83%Color and Shape:SolidMolecular weight:473.88Ref: TM-T8842
1mg138.00€5mg295.00€1mL*10mM (DMSO)309.00€10mg505.00€25mg733.00€50mg888.00€100mg1,251.00€BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41P18IN011
CAS:P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Formula:C15H12N2O5SPurity:97.63%Color and Shape:SolidMolecular weight:332.33DUB-IN-2
CAS:Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.Formula:C15H9N5OPurity:98.96%Color and Shape:SolidMolecular weight:275.26Ref: TM-T11111
1mg54.00€5mg155.00€1mL*10mM (DMSO)169.00€10mg233.00€25mg467.00€50mg682.00€100mg990.00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:>99.99%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg124.00€2mg170.00€5mg260.00€1mL*10mM (DMSO)286.00€10mg409.00€25mg677.00€50mg954.00€100mg1,288.00€Y16 acetate(429653-73-6 free base)
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoAFormula:C51H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1091.24BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3BVDV-IN-1
CAS:BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Formula:C20H22N4OPurity:98.43%Color and Shape:SolidMolecular weight:334.41Ref: TM-T9103
1mg38.00€5mg86.00€1mL*10mM (DMSO)95.00€10mg124.00€25mg241.00€50mg355.00€100mg507.00€200mg687.00€Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purity:97.64% - 98.59%Color and Shape:SolidMolecular weight:452.51Ref: TM-T6867
2mg46.00€5mg70.00€1mL*10mM (DMSO)74.00€10mg95.00€25mg158.00€50mg236.00€100mg356.00€500mg848.00€Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formula:C14H18ClN3O3SPurity:98.05%Color and Shape:SolidMolecular weight:343.83Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32Ref: TM-T5673
1mg34.00€1mL*10mM (DMSO)71.00€5mg73.00€10mg94.00€25mg177.00€50mg323.00€100mg460.00€200mg622.00€STAMBP-IN-1
CAS:STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFormula:C27H28N4O4SPurity:99.64%Color and Shape:SolidMolecular weight:504.6Ref: TM-T8706
1mg67.00€5mg152.00€1mL*10mM (DMSO)192.00€10mg236.00€25mg507.00€50mg730.00€100mg1,018.00€LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39Ref: TM-T4061
1mg35.00€5mg79.00€1mL*10mM (DMSO)94.00€10mg111.00€25mg215.00€50mg319.00€100mg442.00€200mg583.00€α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Formula:C16H26N4O11Purity:98.46%Color and Shape:SolidMolecular weight:450.4MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg52.00€5mg124.00€1mL*10mM (DMSO)136.00€10mg177.00€25mg301.00€50mg424.00€100mg605.00€200mg797.00€HMN-214
CAS:HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Formula:C22H20N2O5SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:424.47Ref: TM-T2438
1mg38.00€2mg50.00€5mg80.00€1mL*10mM (DMSO)87.00€10mg117.00€25mg207.00€50mg333.00€100mg477.00€500mg1,063.00€TAK-960
CAS:TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Formula:C27H34F3N7O3Purity:97.06%Color and Shape:SolidMolecular weight:561.6Ref: TM-T7200
1mg60.00€2mg85.00€5mg114.00€10mg161.00€1mL*10mM (DMSO)161.00€25mg279.00€50mg464.00€100mg672.00€PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5Cyclo(-RGDfK) TFA
CAS:Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.69RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formula:C23H20N6O3Purity:99.04% - 99.72%Color and Shape:SolidMolecular weight:428.44RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Formula:C16H14N2O2SPurity:98.81%Color and Shape:SolidMolecular weight:298.36Ref: TM-T8591
1mg120.00€1mL*10mM (DMSO)243.00€5mg264.00€10mg395.00€25mg627.00€50mg890.00€100mg1,198.00€200mg1,603.00€5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.Formula:C8H13N3SPurity:99.03%Color and Shape:SolidMolecular weight:183.27NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.76T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53Ref: TM-T5416
1mg48.00€5mg96.00€1mL*10mM (DMSO)107.00€10mg144.00€25mg254.00€50mg424.00€100mg627.00€200mg998.00€DUB-IN-1
CAS:DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).Formula:C20H11N5OPurity:98.33% - 98.96%Color and Shape:SolidMolecular weight:337.33Ref: TM-T11110
1mg62.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg173.00€25mg334.00€50mg469.00€100mg618.00€200mg848.00€GNE-6776
CAS:GNE-6776 is a selective USP7 inhibitor.Formula:C20H20N4O2Purity:96.59% - 98.2%Color and Shape:SolidMolecular weight:348.4PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Formula:C18H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:342.82Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Formula:C22H22FN5O7Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:487.44Ref: TM-TQ0063
1mg105.00€5mg245.00€1mL*10mM (DMSO)264.00€10mg389.00€25mg645.00€50mg888.00€100mg1,234.00€500mg2,457.00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formula:C36H48N6O9Purity:99.33%Color and Shape:SolidMolecular weight:708.8SR18662
SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Formula:C16H19Cl2N3O4SPurity:98.97% - 99.2%Color and Shape:SolidMolecular weight:420.31Ref: TM-T22429
1mg46.00€5mg90.00€1mL*10mM (DMSO)100.00€10mg152.00€25mg295.00€50mg475.00€100mg680.00€200mg888.00€500mg1,378.00€BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34Aurora kinase inhibitor-2
CAS:Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Formula:C23H20N4O3Purity:98.66%Color and Shape:SolidMolecular weight:400.43Ref: TM-T9040
1mg63.00€5mg138.00€1mL*10mM (DMSO)150.00€10mg200.00€25mg360.00€50mg532.00€100mg788.00€200mg1,063.00€MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Formula:C24H25F3N6SPurity:98% - 99.92%Color and Shape:SolidMolecular weight:486.56GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Formula:C29H30N8O5Purity:99.14% - 99.71%Color and Shape:SolidMolecular weight:570.6GDC0575 monohydrochloride
CAS:GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.Formula:C16H21BrClN5OPurity:97.85%Color and Shape:SolidMolecular weight:414.73Ref: TM-T27407
1mg43.00€2mg55.00€5mg80.00€1mL*10mM (DMSO)93.00€10mg103.00€25mg177.00€50mg255.00€100mg356.00€200mg520.00€TH5427 hydrochloride
CAS:TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.Formula:C20H21Cl3N8O3Color and Shape:SolidMolecular weight:527.79OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurity:98.69%Color and Shape:SolidMolecular weight:533.59Ref: TM-T5485
1mg88.00€5mg187.00€1mL*10mM (DMSO)220.00€10mg298.00€25mg533.00€50mg755.00€100mg1,008.00€200mg1,359.00€Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purity:95.29% - >99.99%Color and Shape:SolidMolecular weight:603.67CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurity:99.66%Color and Shape:SolidMolecular weight:486.38Ref: TM-T8930
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg85.00€25mg159.00€50mg244.00€100mg359.00€200mg512.00€TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.13Ref: TM-T2069
1mg37.00€2mg48.00€5mg72.00€1mL*10mM (DMSO)79.00€10mg96.00€25mg188.00€50mg366.00€100mg545.00€HMN-176
CAS:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Formula:C20H18N2O4SPurity:98.92% - 98.99%Color and Shape:SolidMolecular weight:382.43Ref: TM-T3643
1mg40.00€2mg52.00€1mL*10mM (DMSO)74.00€5mg84.00€10mg113.00€25mg178.00€50mg333.00€100mg495.00€500mg1,071.00€DMT-2′Fluoro-dU Phosphoramidite
CAS:DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Formula:C39H46FN4O8PPurity:99.5%Color and Shape:SolidMolecular weight:748.78Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Formula:C13H16NNaO4SPurity:99.64%Color and Shape:SolidMolecular weight:305.32InhA-IN-2
CAS:N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.Formula:C16H15ClN2O2S2Purity:98.4%Color and Shape:SolidMolecular weight:366.89Ref: TM-T9734
1mg93.00€5mg182.00€1mL*10mM (DMSO)187.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,071.00€
![5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8912.webp&w=3840&q=75)
