Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(95 products)
- CDK(501 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(262 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
Show 10 more subcategories
Found 3485 products of "Cell Cycle/Checkpoint"
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Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Formula:C28H33N5O4SPurity:98.33%Color and Shape:SolidMolecular weight:535.663,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formula:C7H10BrNO2Purity:98.49%Color and Shape:Light Beige Crystalline PowderMolecular weight:220.062'-Fluorothymidine
CAS:<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Formula:C10H13FN2O5Purity:99.67%Color and Shape:SolidMolecular weight:260.2210-Deazaaminopterin
CAS:<p>10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.</p>Formula:C20H21N7O5Color and Shape:SolidMolecular weight:439.42Digeranyl bisphosphonate
CAS:<p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>Formula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Formula:C29H36ClN5O4Purity:98%Color and Shape:SolidMolecular weight:554.08DNA Gyrase-IN-5
CAS:<p>DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.</p>Formula:C25H15BrClN5Color and Shape:SolidMolecular weight:500.78Syntelin
CAS:<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Formula:C21H20N6O2S3Color and Shape:SolidMolecular weight:484.62Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formula:C16H18N8O2SColor and Shape:SolidMolecular weight:386.43MDK6204
CAS:<p>MDK6204 is a selective inhibitor of CLK1 and CLK2.</p>Formula:C20H20N6OPurity:98%Color and Shape:SolidMolecular weight:360.41Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Formula:C15H21N5O7SColor and Shape:SolidMolecular weight:415.42Cyclapolin 9
CAS:<p>Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.</p>Formula:C9H4F3N3O4SPurity:99.5%Color and Shape:SolidMolecular weight:307.21Binucleine 2
CAS:<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Formula:C13H11ClFN5Color and Shape:SolidMolecular weight:291.71Cdc7-IN-4
CAS:<p>Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.</p>Formula:C22H24F3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.45IRE1α kinase-IN-7
CAS:<p>IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic</p>Formula:C28H25F3N6OColor and Shape:SolidMolecular weight:518.531-Methylcytosine
CAS:<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Formula:C5H7N3OPurity:99.88%Color and Shape:SolidMolecular weight:125.13ANI-7
CAS:<p>ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).</p>Formula:C13H8Cl2N2Purity:99.07%Color and Shape:SolidMolecular weight:263.12WF-536 Hydrochloride
CAS:<p>WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.</p>Formula:C14H16ClN3OColor and Shape:SolidMolecular weight:277.75Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formula:C30H32Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:604.95BA-1049
CAS:<p>BA-1049 is a selective ROCK2 inhibitor.</p>Formula:C16H21N3O2SColor and Shape:SolidMolecular weight:319.42M443
CAS:<p>M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.</p>Formula:C31H30F3N7O2Purity:98.95%Color and Shape:SolidMolecular weight:589.61XIE18-6
CAS:<p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>Formula:C18H15NO6SPurity:99.712%Color and Shape:SolidMolecular weight:373.38CI-898 HCl
CAS:<p>CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.</p>Formula:C19H26Cl3N5O3Color and Shape:SolidMolecular weight:478.8CDK4/6-IN-14
CAS:<p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>Formula:C24H27ClFN7OColor and Shape:SolidMolecular weight:483.97IRE1α kinase-IN-9
CAS:<p>IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.</p>Formula:C24H24N2O6Purity:98%Color and Shape:SolidMolecular weight:436.46Trimetrexate glucuronate
CAS:<p>Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.</p>Formula:C25H33N5O10Color and Shape:SolidMolecular weight:563.564TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59Thiarabine
CAS:<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Formula:C9H13N3O4SPurity:98%Color and Shape:SolidMolecular weight:259.28ROCK-IN-4
CAS:<p>ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.</p>Formula:C20H26ClFN4O7SColor and Shape:SolidMolecular weight:520.96USP28-IN-2
CAS:<p>USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.</p>Formula:C23H20Cl2N2O3SColor and Shape:SolidMolecular weight:475.39IRE1α kinase-IN-8
CAS:<p>IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α.</p>Formula:C23H22N2O5Purity:98%Color and Shape:SolidMolecular weight:406.43Dihydro-5-azacytidine acetate
CAS:<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formula:C10H18N4O7Purity:98%Color and Shape:SolidMolecular weight:306.27Cdc7-IN-5
CAS:<p>Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.</p>Formula:C25H23N3O5Purity:97.15%Color and Shape:SolidMolecular weight:445.47JH-XIV-68-3
CAS:<p>JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.</p>Formula:C21H17F3N8OColor and Shape:SolidMolecular weight:454.41CM03
CAS:<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Formula:C34H44N6O6Purity:98.65%Color and Shape:SolidMolecular weight:632.75Akt1&PKA-IN-2
CAS:<p>Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.</p>Formula:C20H17Cl2N3OColor and Shape:SolidMolecular weight:386.27CDK1-IN-1
CAS:<p>CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.</p>Formula:C27H23N5O3Color and Shape:SolidMolecular weight:465.5Werner syndrome RecQ helicase-IN-4
CAS:<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Formula:C32H33F3N8O5Purity:98.27%Color and Shape:SolidMolecular weight:666.65FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.45-Aminouridine
CAS:<p>5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.</p>Formula:C9H13N3O6Purity:99.53%Color and Shape:SolidMolecular weight:259.22CDK7-IN-2
CAS:<p>CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.</p>Formula:C26H39N7O3Color and Shape:SolidMolecular weight:497.63CB10-277
CAS:<p>CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.</p>Formula:C9H11N3O2Color and Shape:SolidMolecular weight:193.2Edatrexate
CAS:<p>Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.</p>Formula:C22H25N7O5Color and Shape:SolidMolecular weight:467.48Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Formula:C17H17FN4OS2Color and Shape:SolidMolecular weight:376.47CDK4/6-IN-7
CAS:<p>CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.</p>Formula:C18H18ClN5O3Color and Shape:SolidMolecular weight:387.82BI8622
CAS:<p>BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.</p>Formula:C25H26N6OPurity:98.28%Color and Shape:SolidMolecular weight:426.51Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Formula:C31H55N3O6Purity:97.22%Color and Shape:SolidMolecular weight:565.78CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Formula:C28H24ClN3O3Color and Shape:SolidMolecular weight:485.96DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formula:C17H12Cl2N2O2Purity:99.34%Color and Shape:SolidMolecular weight:347.2αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67SPC-839
CAS:<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Formula:C18H14N4O3SColor and Shape:SolidMolecular weight:366.39ARN22089
CAS:<p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>Formula:C23H27N5Purity:98.37%Color and Shape:SolidMolecular weight:373.49MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55TH470
CAS:<p>TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,</p>Formula:C30H31N5O5S2Color and Shape:SolidMolecular weight:605.73cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Formula:C23H17FN2O4Color and Shape:SolidMolecular weight:404.39Aurora kinase inhibitor-10
CAS:<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Formula:C21H19F5N6O4SColor and Shape:SolidMolecular weight:546.47Dyrk1A-IN-5
CAS:<p>Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.</p>Formula:C16H9IN2O2Color and Shape:SolidMolecular weight:388.16Crozbaciclib fumarate
CAS:<p>Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.</p>Formula:C32H34F2N6O4Color and Shape:SolidMolecular weight:604.65Mequindox
CAS:<p>Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].</p>Formula:C11H10N2O3Color and Shape:SolidMolecular weight:218.21SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Formula:C34H26N6O2Purity:98%Color and Shape:SolidMolecular weight:550.61CRT-0105446
CAS:<p>CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Formula:C20H18F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:421.44Akt1&PKA-IN-1
CAS:<p>Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.</p>Formula:C20H17Cl2N3OColor and Shape:SolidMolecular weight:386.27Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Formula:C24H31N7Color and Shape:SolidMolecular weight:417.555-Ethynyluridine
CAS:<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Formula:C11H12N2O6Purity:99.78%Color and Shape:SolidMolecular weight:268.22Aurora Kinases-IN-3
CAS:<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Formula:C20H16F3N3O4Color and Shape:SolidMolecular weight:419.35TCS 2312
CAS:<p>checkpoint kinase 1 (chk1) inhibitor</p>Formula:C25H24N4O2Purity:98%Color and Shape:SolidMolecular weight:412.48Trimetrexate
CAS:Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.Formula:C19H23N5O3Purity:98%Color and Shape:SolidMolecular weight:369.42Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formula:C15H13F3N2O2Purity:99.86%Color and Shape:SolidMolecular weight:310.27SRPIN-803
CAS:<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Formula:C14H9F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:370.31GSK317354A
CAS:<p>GSK317354A is a GRK2 inhibitor.</p>Formula:C25H18F4N6OColor and Shape:SolidMolecular weight:494.44BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formula:C27H30N4O3Purity:98%Color and Shape:SolidMolecular weight:458.55CDK8-IN-4
CAS:<p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>Formula:C20H18N4OColor and Shape:SolidMolecular weight:330.38CDK12-IN-3
CAS:<p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>Formula:C23H28F2N8OPurity:99.85%Color and Shape:SolidMolecular weight:470.52DNA Gyrase-IN-4
CAS:<p>DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.</p>Formula:C22H15Cl2NO4SColor and Shape:SolidMolecular weight:460.33FUBP1-IN-2
CAS:<p>FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.</p>Formula:C26H26ClN3O4Color and Shape:SolidMolecular weight:479.96Cdc7-IN-1
CAS:<p>Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.</p>Formula:C21H16ClN3O4Color and Shape:SolidMolecular weight:409.82IXA6
CAS:<p>IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.</p>Formula:C22H20ClN3O3SPurity:98.63%Color and Shape:SolidMolecular weight:441.93KSI-3716
CAS:<p>KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.</p>Formula:C17H11BrCl2N2O2Purity:98.94%Color and Shape:SolidMolecular weight:426.09CLK1/2-IN-3
CAS:<p>CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.</p>Formula:C21H21N5O2Purity:99.04%Color and Shape:SolidMolecular weight:375.42360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Formula:C27H23I2N5O2Purity:98%Color and Shape:SolidMolecular weight:703.31CDK12-IN-E9
CAS:<p>CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.</p>Formula:C24H30N6O2Color and Shape:SolidMolecular weight:434.53PD-1/PD-L1-IN-NP19
CAS:<p>PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.</p>Formula:C33H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:555.06NSC 625987
CAS:<p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>Formula:C15H13NO2SPurity:98%Color and Shape:SolidMolecular weight:271.33AS2863619 free base
CAS:<p>AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.</p>Formula:C16H12N8OColor and Shape:SolidMolecular weight:332.325,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Formula:C21H22N6O5Purity:98%Color and Shape:SolidMolecular weight:438.44HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Formula:C22H21ClN2O5Color and Shape:SolidMolecular weight:428.87Centrinone-B
CAS:<p>Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.</p>Formula:C27H27F2N7O5S2Purity:98.71%Color and Shape:SolidMolecular weight:631.67MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Formula:C24H25N3O3SColor and Shape:SolidMolecular weight:435.54L 888607 Racemate
CAS:<p>L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.</p>Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84Ilorasertib hydrochloride
CAS:<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Formula:C25H22ClFN6O2SPurity:98.45%Color and Shape:SolidMolecular weight:525CLK1-IN-1
CAS:<p>CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).</p>Formula:C24H16FN5OColor and Shape:SolidMolecular weight:409.42THZ1-R
CAS:<p>THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.</p>Formula:C31H30ClN7O2Purity:98%Color and Shape:SolidMolecular weight:568.07Antibacterial agent 124
CAS:<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Formula:C16H17ClFN3O2Color and Shape:SolidMolecular weight:337.78JA2131
CAS:<p>JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.</p>Formula:C13H19N5O2S2Color and Shape:SolidMolecular weight:341.45Poloxipan
CAS:<p>Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.</p>Formula:C14H10BrN3O3SColor and Shape:SolidMolecular weight:380.22Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Formula:C20H22N4O5SPurity:99.39% - 99.39%Color and Shape:SolidMolecular weight:430.48
