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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • Trilaciclib hydrochloride

    CAS:
    <p>Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).</p>
    Formula:C24H32Cl2N8O
    Purity:99.69% - 99.89%
    Color and Shape:Solid
    Molecular weight:519.47
  • MYCi975

    CAS:
    <p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>
    Formula:C25H16Cl2F6N2O2
    Purity:99.3% - 99.82%
    Color and Shape:Solid
    Molecular weight:561.3
  • SU056

    CAS:
    <p>SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.</p>
    Formula:C20H16FNO5
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:369.34
  • Enrofloxacin

    CAS:
    <p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>
    Formula:C19H22FN3O3
    Purity:99.43% - >99.99%
    Color and Shape:Pale Yellow Crystals
    Molecular weight:359.39
  • NU6140

    CAS:
    <p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>
    Formula:C23H30N6O2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:422.52
  • TAK-901

    CAS:
    <p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>
    Formula:C28H32N4O3S
    Purity:99.02% - 99.59%
    Color and Shape:Solid
    Molecular weight:504.64
  • R-10015

    CAS:
    <p>R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.</p>
    Formula:C20H19ClN6O2
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:410.86
  • Metarrestin

    CAS:
    <p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>
    Formula:C31H30N4O
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:474.6
  • Abrilumab

    CAS:
    <p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>
    Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)
    Color and Shape:Liquid
  • Tadocizumab

    CAS:
    <p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>
    Purity:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)
    Color and Shape:Liquid
  • CDK2-IN-4

    CAS:
    <p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>
    Formula:C23H18N6O2S
    Purity:97.24% - 99.10%
    Color and Shape:Solid
    Molecular weight:442.49
  • Ribociclib succinate

    CAS:
    <p>Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>
    Formula:C27H36N8O5
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:552.63
  • JH-RE-06

    CAS:
    <p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>
    Formula:C20H16Cl3N3O4
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:468.72
  • Mps1-IN-3

    CAS:
    <p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>
    Formula:C26H31N7O4S
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:537.63
  • GSK-1520489A

    CAS:
    <p>GSK-1520489A is an active PKMYT1 inhibitor.</p>
    Formula:C21H23N5O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:425.5
  • Vitamin D2

    CAS:
    <p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>
    Formula:C28H44O
    Purity:98.73% - 99.89%
    Color and Shape:Prisms From Acetone 1998)
    Molecular weight:396.65
  • DI-87

    CAS:
    <p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>
    Formula:C23H30N6O3S2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:502.65
  • Hycanthone

    CAS:
    <p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>
    Formula:C20H24N2O2S
    Purity:98.78%
    Color and Shape:Yellow-Orange Powder (Ntp 1992)
    Molecular weight:356.48
  • XPW1

    CAS:
    <p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>
    Formula:C36H39ClFN7O2
    Purity:98.08%
    Color and Shape:Soild
    Molecular weight:656.19
  • Efalizumab

    CAS:
    <p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>
    Purity:SDS-PAGE:95% SEC-HPLC:98.77%
    Color and Shape:Liquid
    Molecular weight:146.14 kDa