Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(70 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
Show 10 more subcategories
Found 3477 products of "Cell Cycle/Checkpoint"
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Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaOrbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.426-Mercaptopurine
CAS:<p>6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.</p>Formula:C5H4N4SPurity:99.53% - 99.63%Color and Shape:Yellow Crystalline Powder SolidMolecular weight:152.18Levofloxacin hydrate
CAS:<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:Pale Yellow SolidMolecular weight:370.38ATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67BMS-1001 hydrochloride
CAS:<p>BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect</p>Formula:C35H35ClN2O7Purity:97.36%Color and Shape:SolidMolecular weight:631.11TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Formula:C28H32N4O3SPurity:99.02% - 99.59%Color and Shape:SolidMolecular weight:504.64Abciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaRifaximin
CAS:<p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>Formula:C43H51N3O11Purity:99.18% - 99.40%Color and Shape:Red-Orange Crystalline PowderMolecular weight:785.88HLM006474
CAS:<p>HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).</p>Formula:C25H25N3O2Purity:98.45% - 99.04%Color and Shape:SolidMolecular weight:399.48Avotaciclib
CAS:<p>Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic</p>Formula:C13H11N7OPurity:98.02%Color and Shape:SolidMolecular weight:281.27Lerociclib dihydrochloride
CAS:<p>Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/</p>Formula:C26H36Cl2N8OPurity:97.4%Color and Shape:SolidMolecular weight:547.52Foralumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidBMVC-8C3O
CAS:<p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>Formula:C42H53I3N4O3Purity:99.72%Color and Shape:SolidMolecular weight:1042.61Trilaciclib hydrochloride
CAS:<p>Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).</p>Formula:C24H32Cl2N8OPurity:99.69% - 99.89%Color and Shape:SolidMolecular weight:519.47NU6140
CAS:<p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.82%Color and Shape:SolidMolecular weight:561.3Cirtuvivint
CAS:<p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>Formula:C24H25N7OPurity:99.46% - >99.99%Color and Shape:SolidMolecular weight:427.5Cinoxacin
CAS:<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Formula:C12H10N2O5Purity:99.62% - 99.98%Color and Shape:SolidMolecular weight:262.22Cibisatamab
CAS:<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaButylparaben
CAS:<p>Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.</p>Formula:C11H14O3Purity:98.15%Color and Shape:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Molecular weight:194.23LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formula:C20H21N7O7Purity:99.7%Color and Shape:SolidMolecular weight:471.42BT173
CAS:<p>BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.</p>Formula:C18H12BrN3O2Purity:98.247%Color and Shape:SolidMolecular weight:382.21Procaine
CAS:<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Formula:C13H20N2O2Purity:99.57% - 99.73%Color and Shape:Anhydrous Plates Tables From Ligroin Or Ether SolidMolecular weight:236.31Tidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Purity:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:LiquidOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Purity:>95%Color and Shape:LiquidJH-RE-06
CAS:<p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>Formula:C20H16Cl3N3O4Purity:99.29%Color and Shape:SolidMolecular weight:468.72Carmofur
CAS:<p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>Formula:C11H16FN3O3Purity:98.53% - 99.98%Color and Shape:SolidMolecular weight:257.26Mps1-IN-3
CAS:<p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Hu7691 free base
CAS:<p>Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.</p>Formula:C22H21F3N4OPurity:98.89%Color and Shape:SolidMolecular weight:414.423GSK-1520489A
CAS:<p>GSK-1520489A is an active PKMYT1 inhibitor.</p>Formula:C21H23N5O3SPurity:99.85%Color and Shape:SolidMolecular weight:425.5Enrofloxacin
CAS:<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Formula:C19H22FN3O3Purity:99.43% - >99.99%Color and Shape:Pale Yellow CrystalsMolecular weight:359.39SU056
CAS:<p>SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.</p>Formula:C20H16FNO5Purity:99.89%Color and Shape:SoildMolecular weight:369.34R-10015
CAS:<p>R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.</p>Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86XPW1
CAS:<p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>Formula:C36H39ClFN7O2Purity:98.08%Color and Shape:SoildMolecular weight:656.19Vitamin D2
CAS:<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Formula:C28H44OPurity:98.73% - 99.89%Color and Shape:Prisms From Acetone 1998)Molecular weight:396.65Efalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaHycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48DI-87
CAS:<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Formula:C23H30N6O3S2Purity:99.76%Color and Shape:SolidMolecular weight:502.65Ceftriaxone sodium hydrate
CAS:<p>Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.</p>Formula:C18H16N8Na2O7S3·5H2OPurity:99.77% - 99.78%Color and Shape:White Or Almost White Crystalline Powder OdorlessMolecular weight:661.6Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidCyclin K degrader 1
<p>Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.</p>Formula:C23H17Cl2N5O2Purity:99.76%Color and Shape:SolidMolecular weight:466.32Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Formula:C31H30N4OPurity:99.45%Color and Shape:SolidMolecular weight:474.6Gemifloxacin mesylate
CAS:<p>Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually</p>Formula:C19H24FN5O7SPurity:97.24% - ≥95%Color and Shape:Beige SolidMolecular weight:485.49hSMG-1 inhibitor 11j
CAS:<p>hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.</p>Formula:C27H28ClN7O3SPurity:99.22% - 99.65%Color and Shape:SolidMolecular weight:566.07Ribociclib succinate
CAS:<p>Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>Formula:C27H36N8O5Purity:99.9%Color and Shape:SolidMolecular weight:552.63CDK2-IN-4
CAS:<p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>Formula:C23H18N6O2SPurity:97.24% - 99.10%Color and Shape:SolidMolecular weight:442.49Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Purity:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Color and Shape:LiquidTAO Kinase inhibitor 2
CAS:<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Formula:C25H24N2O3Purity:98.58%Color and Shape:SoildMolecular weight:400.47MKC8866
CAS:<p>MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.</p>Formula:C18H19NO7Purity:99.28% - 99.854%Color and Shape:SolidMolecular weight:361.35
