Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(545 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(249 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3860 products of "Cell Cycle/Checkpoint"
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Lerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Formula:C26H36Cl2N8OPurity:97.4%Color and Shape:SolidMolecular weight:547.52Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.91%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg46.00€10mg58.00€25mg92.00€50mg160.00€100mg236.00€200mg353.00€500mg580.00€1mL*10mM (DMSO)49.00€Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaOtelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purity:>95%Color and Shape:LiquidTegafur
CAS:Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.Formula:C8H9FN2O3Purity:99.16% - 99.89%Color and Shape:White Crystalline PowderMolecular weight:200.17Centrinone
CAS:Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).Formula:C26H25F2N7O6S2Purity:98.76%Color and Shape:SolidMolecular weight:633.65Cirtuvivint
CAS:Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.Formula:C24H25N7OPurity:99.95% - 99.96%Color and Shape:SolidMolecular weight:427.5Cyclin K degrader 1
Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.Formula:C23H17Cl2N5O2Purity:99.76%Color and Shape:SolidMolecular weight:466.32HLM006474
CAS:HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).Formula:C25H25N3O2Purity:99.04% - 99.20%Color and Shape:SolidMolecular weight:399.48Procaine
CAS:Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.
Formula:C13H20N2O2Purity:99.57% - 99.73%Color and Shape:Anhydrous Plates Tables From Ligroin Or Ether SolidMolecular weight:236.31Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Formula:C22H21F3N4OPurity:98.89%Color and Shape:SolidMolecular weight:414.423MKC8866
CAS:MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.Formula:C18H19NO7Purity:99.28% - 99.854%Color and Shape:SolidMolecular weight:361.35Ref: TM-T15594
1mg84.00€2mg109.00€5mg177.00€10mg250.00€25mg423.00€50mg557.00€100mg760.00€200mg1,018.00€1mL*10mM (DMSO)192.00€TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Formula:C19H15Cl2NO3Purity:97.22%Color and Shape:SolidMolecular weight:376.23Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Formula:C14H18N4O3Purity:99.80% - 99.81%Color and Shape:White To Yellowish PowderMolecular weight:290.32TAK-901
CAS:TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFormula:C28H32N4O3SPurity:99.02% - 99.59%Color and Shape:SolidMolecular weight:504.64Ref: TM-T2709
1mg35.00€5mg70.00€10mg104.00€25mg202.00€50mg329.00€100mg525.00€200mg748.00€1mL*10mM (DMSO)79.00€MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.82%Color and Shape:SolidMolecular weight:561.3Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaCinoxacin
CAS:Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.Formula:C12H10N2O5Purity:99.62% - 99.98%Color and Shape:SolidMolecular weight:262.22Gemifloxacin mesylate
CAS:Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventuallyFormula:C19H24FN5O7SPurity:97.24% - ≥95%Color and Shape:Beige SolidMolecular weight:485.49LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for
Formula:C20H21N7O7Purity:99.7%Color and Shape:SolidMolecular weight:471.42Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaTAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
Formula:C25H24N2O3Purity:98.58%Color and Shape:SoildMolecular weight:400.47ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Carmofur
CAS:Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Formula:C11H16FN3O3Purity:98.53% - 99.98%Color and Shape:SolidMolecular weight:257.26BMVC-8C3O
CAS:BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.Formula:C42H53I3N4O3Purity:99.72%Color and Shape:SolidMolecular weight:1042.61Ref: TM-T13584
1mg101.00€5mg192.00€10mg285.00€25mg462.00€50mg623.00€100mg858.00€200mg1,153.00€1mL*10mM (DMSO)371.00€Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.42JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Formula:C20H16Cl3N3O4Purity:99.29%Color and Shape:SolidMolecular weight:468.72Ref: TM-T15611
1mg44.00€5mg93.00€10mg152.00€25mg334.00€50mg587.00€100mg1,044.00€1mL*10mM (DMSO)95.00€Rifapentine
CAS:Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.Formula:C47H64N4O12Purity:95.74% - ≥98%Color and Shape:SolidMolecular weight:877.03Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg34.00€5mg54.00€10mg87.00€25mg149.00€50mg255.00€100mg384.00€200mg538.00€1mL*10mM (DMSO)64.00€SIBA
CAS:SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formula:C14H21N5O3SPurity:99.48%Color and Shape:SolidMolecular weight:339.41Ref: TM-T12908
1mg52.00€5mg94.00€10mg117.00€25mg220.00€50mg329.00€100mg469.00€200mg652.00€1mL*10mM (DMSO)104.00€GSK-1520489A
CAS:GSK-1520489A is an active PKMYT1 inhibitor.Formula:C21H23N5O3SPurity:99.85%Color and Shape:SolidMolecular weight:425.5NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Ref: TM-T16359
2mg39.00€5mg60.00€10mg92.00€25mg177.00€50mg285.00€100mg414.00€200mg580.00€1mL*10mM (DMSO)67.00€SU056
CAS:SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
Formula:C20H16FNO5Purity:99.89%Color and Shape:SoildMolecular weight:369.34R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86Ref: TM-T12609
1mg50.00€5mg112.00€10mg170.00€25mg280.00€50mg371.00€100mg525.00€200mg712.00€1mL*10mM (DMSO)124.00€XPW1
CAS:XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.Formula:C36H39ClFN7O2Purity:98.08%Color and Shape:SoildMolecular weight:656.19Vitamin D2
CAS:Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.Formula:C28H44OPurity:98.73% - 99.89%Color and Shape:Prisms From Acetone 1998)Molecular weight:396.65Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Formula:C18H16N8Na2O7S3·5H2OPurity:99.77% - 99.78%Color and Shape:White Or Almost White Crystalline Powder OdorlessMolecular weight:661.6Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formula:C23H30N6O3S2Purity:99.76%Color and Shape:SolidMolecular weight:502.65Rifaximin
CAS:Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.Formula:C43H51N3O11Purity:99.18% - 99.40%Color and Shape:Red-Orange Crystalline PowderMolecular weight:785.88Butylparaben
CAS:Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.Formula:C11H14O3Purity:98.15%Color and Shape:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Molecular weight:194.23hSMG-1 inhibitor 11j
CAS:hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
Formula:C27H28ClN7O3SPurity:99.22% - 99.65%Color and Shape:SolidMolecular weight:566.07Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
Formula:C31H30N4OPurity:99.45%Color and Shape:SolidMolecular weight:474.6Ref: TM-T12006
1mg40.00€2mg52.00€5mg88.00€10mg144.00€25mg298.00€50mg512.00€100mg740.00€500mg1,539.00€Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:Pale Yellow SolidMolecular weight:370.38BT173
CAS:BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.Formula:C18H12BrN3O2Purity:98.247%Color and Shape:SolidMolecular weight:382.21Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Formula:C27H36N8O5Purity:99.9%Color and Shape:SolidMolecular weight:552.63Ref: TM-T15732
2mg34.00€5mg49.00€10mg70.00€25mg92.00€50mg109.00€100mg165.00€200mg258.00€500mg459.00€1mL*10mM (DMSO)60.00€CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Formula:C23H18N6O2SPurity:97.24% - 99.10%Color and Shape:SolidMolecular weight:442.49Ref: TM-T14916
1mg82.00€5mg192.00€10mg304.00€25mg522.00€50mg713.00€100mg1,018.00€1mL*10mM (DMSO)212.00€Trilaciclib hydrochloride
CAS:Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Formula:C24H32Cl2N8OPurity:99.69% - 99.89%Color and Shape:SolidMolecular weight:519.47Enrofloxacin
CAS:Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
Formula:C19H22FN3O3Purity:99.43% - >99.99%Color and Shape:Pale Yellow CrystalsMolecular weight:359.39NMDI14
CAS:NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).Formula:C21H25N3O4SPurity:97.79% - 99.37%Color and Shape:SolidMolecular weight:415.51Ref: TM-T12235
1mg35.00€5mg74.00€10mg119.00€25mg236.00€50mg356.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)84.00€
