Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(545 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(249 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3860 products of "Cell Cycle/Checkpoint"
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Diaveridine
CAS:Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide.Formula:C13H16N4O2Purity:99.10%Color and Shape:White SolidMolecular weight:260.29Enoxacin hydrate
CAS:Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.Formula:C15H17FN4O3H2OPurity:99.50%Color and Shape:SolidMolecular weight:347.34AZ1495
CAS:AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.Formula:C21H31N5O2Purity:98.81%Color and Shape:SolidMolecular weight:385.5Ref: TM-T14367
1mg93.00€5mg156.00€10mg245.00€25mg349.00€50mg494.00€100mg750.00€200mg1,009.00€1mL*10mM (DMSO)170.00€Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Formula:C27H36N8O5Purity:99.9%Color and Shape:SolidMolecular weight:552.63Ref: TM-T15732
2mg34.00€5mg49.00€10mg70.00€25mg92.00€50mg109.00€100mg165.00€200mg258.00€500mg459.00€1mL*10mM (DMSO)60.00€JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Formula:C20H16Cl3N3O4Purity:99.29%Color and Shape:SolidMolecular weight:468.72Ref: TM-T15611
1mg44.00€5mg93.00€10mg152.00€25mg334.00€50mg587.00€100mg1,044.00€1mL*10mM (DMSO)95.00€DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formula:C15H11N3O2Purity:98.14%Color and Shape:SolidMolecular weight:265.27AZ-Dyrk1B-33
CAS:AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.Formula:C19H16N4Purity:99.91%Color and Shape:SolidMolecular weight:300.36Ref: TM-T14364
1mg44.00€5mg92.00€10mg147.00€25mg289.00€50mg419.00€100mg583.00€200mg787.00€1mL*10mM (DMSO)100.00€Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Formula:C12H13ClN4Purity:99.67%Color and Shape:CrystalsMolecular weight:248.71Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg34.00€5mg54.00€10mg87.00€25mg149.00€50mg255.00€100mg384.00€200mg538.00€1mL*10mM (DMSO)64.00€HBX 19818
CAS:HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).Formula:C25H28ClN3OPurity:97.71%Color and Shape:SolidMolecular weight:421.96Ref: TM-T15464
1mg35.00€5mg80.00€10mg111.00€25mg177.00€50mg253.00€100mg353.00€200mg502.00€1mL*10mM (DMSO)89.00€TAME hydrochloride
CAS:TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.Formula:C14H23ClN4O4SPurity:99.11% - 99.21%Color and Shape:White Fine Crystalline PowderMolecular weight:378.87Netarsudil Dihydrochloride
CAS:Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.Formula:C28H29Cl2N3O3Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:526.45GSK-1520489A
CAS:GSK-1520489A is an active PKMYT1 inhibitor.Formula:C21H23N5O3SPurity:99.85%Color and Shape:SolidMolecular weight:425.5XPW1
CAS:XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.Formula:C36H39ClFN7O2Purity:98.08%Color and Shape:SoildMolecular weight:656.19Cyclin K degrader 1
Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.Formula:C23H17Cl2N5O2Purity:99.76%Color and Shape:SolidMolecular weight:466.32Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaCirtuvivint
CAS:Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.Formula:C24H25N7OPurity:99.95% - 99.96%Color and Shape:SolidMolecular weight:427.5Butylparaben
CAS:Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.Formula:C11H14O3Purity:98.15%Color and Shape:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Molecular weight:194.23LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for
Formula:C20H21N7O7Purity:99.7%Color and Shape:SolidMolecular weight:471.42HLM006474
CAS:HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).Formula:C25H25N3O2Purity:99.04% - 99.20%Color and Shape:SolidMolecular weight:399.48TAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
Formula:C25H24N2O3Purity:98.58%Color and Shape:SoildMolecular weight:400.47MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.82%Color and Shape:SolidMolecular weight:561.3Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purity:>95%Color and Shape:LiquidLerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Formula:C26H36Cl2N8OPurity:97.4%Color and Shape:SolidMolecular weight:547.52TAK-901
CAS:TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFormula:C28H32N4O3SPurity:99.02% - 99.59%Color and Shape:SolidMolecular weight:504.64Ref: TM-T2709
1mg35.00€5mg70.00€10mg104.00€25mg202.00€50mg329.00€100mg525.00€200mg748.00€1mL*10mM (DMSO)79.00€Trilaciclib hydrochloride
CAS:Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Formula:C24H32Cl2N8OPurity:99.69% - 99.89%Color and Shape:SolidMolecular weight:519.47Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Ref: TM-T16359
2mg39.00€5mg60.00€10mg92.00€25mg177.00€50mg285.00€100mg414.00€200mg580.00€1mL*10mM (DMSO)67.00€Rifapentine
CAS:Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.Formula:C47H64N4O12Purity:95.74% - ≥98%Color and Shape:SolidMolecular weight:877.03Vitamin D2
CAS:Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.Formula:C28H44OPurity:98.73% - 99.89%Color and Shape:Prisms From Acetone 1998)Molecular weight:396.65R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purity:98.68%Color and Shape:SolidMolecular weight:410.86Ref: TM-T12609
1mg50.00€5mg112.00€10mg170.00€25mg280.00€50mg371.00€100mg525.00€200mg712.00€1mL*10mM (DMSO)124.00€SIBA
CAS:SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formula:C14H21N5O3SPurity:99.48%Color and Shape:SolidMolecular weight:339.41Ref: TM-T12908
1mg52.00€5mg94.00€10mg117.00€25mg220.00€50mg329.00€100mg469.00€200mg652.00€1mL*10mM (DMSO)104.00€Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaPaprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.91%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg46.00€10mg58.00€25mg92.00€50mg160.00€100mg236.00€200mg353.00€500mg580.00€1mL*10mM (DMSO)49.00€SU056
CAS:SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
Formula:C20H16FNO5Purity:99.89%Color and Shape:SoildMolecular weight:369.34DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formula:C23H30N6O3S2Purity:99.76%Color and Shape:SolidMolecular weight:502.65MALAT1-IN-1
CAS:MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.Formula:C19H21N3O2Purity:99.58%Color and Shape:SolidMolecular weight:323.39Ref: TM-T16007
5mg39.00€10mg63.00€25mg120.00€50mg224.00€100mg432.00€200mg623.00€1mL*10mM (DMSO)44.00€Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
Formula:C31H30N4OPurity:99.45%Color and Shape:SolidMolecular weight:474.6Ref: TM-T12006
1mg40.00€2mg52.00€5mg88.00€10mg144.00€25mg298.00€50mg512.00€100mg740.00€500mg1,539.00€Nadifloxacin
CAS:Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.Formula:C19H21FN2O4Purity:99.03% - 99.7%Color and Shape:Off-White Crystalline SolidMolecular weight:360.38Pefloxacin Mesylate Dihydrate
CAS:Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase).Formula:C17H20FN3O3·CH4O3S·2H2OPurity:99.79%Color and Shape:SolidMolecular weight:465.49Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Formula:C18H16N8Na2O7S3·5H2OPurity:99.77% - 99.78%Color and Shape:White Or Almost White Crystalline Powder OdorlessMolecular weight:661.6Ribavirin
CAS:Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Formula:C8H12N4O5Purity:99.09% - 99.83%Color and Shape:Less Solid Colourless SolidMolecular weight:244.20PTBP1-RNA-binding inhibitor P6 TFA
PTBP1-RNA-binding inhibitor P6 TFA is a stapled peptide inhibitor of PTBP1, used to inhibit RNA alternative splicing events regulated by PTBP1.Color and Shape:Odour SolidCa2+ channel agonist 1
CAS:Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.Formula:C19H26N6OPurity:97.71%Color and Shape:SolidMolecular weight:354.45Ref: TM-T10659
1mg97.00€5mg188.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,130.00€1mL*10mM (DMSO)217.00€CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Formula:C23H18N6O2SPurity:97.24% - 99.10%Color and Shape:SolidMolecular weight:442.49Ref: TM-T14916
1mg82.00€5mg192.00€10mg304.00€25mg522.00€50mg713.00€100mg1,018.00€1mL*10mM (DMSO)212.00€Cinoxacin
CAS:Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.Formula:C12H10N2O5Purity:99.62% - 99.98%Color and Shape:SolidMolecular weight:262.22Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Formula:C14H19N5O4Purity:99.85% - 99.99%Color and Shape:Off-White PowderMolecular weight:321.33MKC9989
CAS:MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.Formula:C17H20O7Purity:99.3%Color and Shape:SolidMolecular weight:336.34Ref: TM-T12071
1mg51.00€5mg156.00€10mg226.00€25mg376.00€50mg543.00€100mg730.00€1mL*10mM (DMSO)140.00€BRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Formula:C16H16N4Purity:99.43%Color and Shape:SolidMolecular weight:264.33Ref: TM-T14778
1mg34.00€5mg66.00€10mg92.00€25mg177.00€50mg268.00€100mg398.00€200mg575.00€1mL*10mM (DMSO)73.00€Procaine hydrochloride
CAS:Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.Formula:C13H20N2O2·HClPurity:99.1% - 99.22%Color and Shape:White Crystalline PowderMolecular weight:272.77
