CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3477 products of "Cell Cycle/Checkpoint"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • GRGDSP
    Targetmol
    + Info

    GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Formula:C22H37N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.58

    Ref: TM-TP1421

  • Chrysomycin A
    Targetmol
    + Info

    Chrysomycin A

    CAS:
    <p>Chrysomycin A is an antibiotic that can be derived from Streptomyces.</p>
    Formula:C28H28O9
    Color and Shape:Solid
    Molecular weight:508.52

    Ref: TM-T36467

  • Isocytosine
    Targetmol
    + Info

    Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C4H5N3O
    Color and Shape:White To Off-White Solid
    Molecular weight:111.1

    Ref: TM-PDK0016

  • TLR7 agonist 12
    Targetmol
    + Info

    TLR7 agonist 12

    CAS:
    <p>TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Formula:C14H19N5O8
    Color and Shape:Solid
    Molecular weight:385.33

    Ref: TM-T75213

  • CymitQuimica logo
    Targetmol
    + Info

    Antibacterial agent 144

    <p>Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.</p>
    Formula:C26H23N7O3
    Color and Shape:Solid
    Molecular weight:481.51

    Ref: TM-T79282

  • CymitQuimica logo
    Targetmol
    + Info

    Clofarabine-5'-diphosphate trisodium

    <p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H10ClFN5Na3O9P2
    Color and Shape:Solid
    Molecular weight:529.58

    Ref: TM-T203582

  • CDK7-IN-5
    Targetmol
    + Info

    CDK7-IN-5

    CAS:
    <p>CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).</p>
    Formula:C34H45N9O2
    Color and Shape:Solid
    Molecular weight:611.795

    Ref: TM-T39247

  • 5'-O-DMT-ibu-dC
    Targetmol
    + Info

    5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Formula:C34H37N3O7
    Color and Shape:Solid
    Molecular weight:599.67

    Ref: TM-T38405

  • CymitQuimica logo
    Targetmol
    + Info

    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T78307

  • Ac-dA Phosphoramidite
    Targetmol
    + Info

    Ac-dA Phosphoramidite

    CAS:
    <p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C42H50N7O7P
    Color and Shape:Solid
    Molecular weight:795.878

    Ref: TM-T38425

  • PLK1-IN-2
    Targetmol
    + Info

    PLK1-IN-2

    CAS:
    <p>PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.</p>
    Formula:C24H27FN8OS
    Color and Shape:Solid
    Molecular weight:494.59

    Ref: TM-T40265

  • PROTAC CDK9 degrader-2
    Targetmol
    + Info

    PROTAC CDK9 degrader-2

    CAS:
    <p>PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.</p>
    Formula:C39H36N6O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.74

    Ref: TM-T17728

  • CymitQuimica logo
    Targetmol
    + Info

    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Color and Shape:Solid
    Molecular weight:563.13

    Ref: TM-T74585

  • CymitQuimica logo
    Targetmol
    + Info

    IRE1-IN-2

    <p>IRE1-IN-2 (compound G15) functions as a potent inhibitor of IRE1. It effectively suppresses lipid accumulation induced by FFA, exhibiting an IC50 value of 2.06 μM.</p>
    Formula:C16H20O6
    Color and Shape:Solid
    Molecular weight:308.12599

    Ref: TM-T207625

  • Ac-MRGDH-NH2
    Targetmol
    + Info

    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727

    Ref: TM-TP3057

  • CymitQuimica logo
    Targetmol
    + Info

    Anti-c-myc Antibody (9E10)

    <p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-960

  • CymitQuimica logo
    Targetmol
    + Info

    DSPE-PEG3000-iRGD

    <p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>
    Color and Shape:Odour Solid

    Ref: TM-TCL-01149

  • α-Methyl-DL-aspartic acid
    Targetmol
    + Info

    α-Methyl-DL-aspartic acid

    CAS:
    <p>α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.</p>
    Formula:C5H9NO4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:147.13

    Ref: TM-T78044

  • MRK-952
    Targetmol
    + Info

    MRK-952

    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Formula:C20H20ClF3N6
    Color and Shape:Solid
    Molecular weight:436.861

    Ref: TM-T205743

  • Pseudouridimycin
    Targetmol
    + Info

    Pseudouridimycin

    CAS:
    <p>Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.</p>
    Formula:C17H26N8O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.44

    Ref: TM-T16673

  • WRN inhibitor 17
    Targetmol
    + Info

    WRN inhibitor 17

    CAS:
    <p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>
    Formula:C33H34F4N4O6S
    Color and Shape:Solid
    Molecular weight:690.71

    Ref: TM-T203305

  • CymitQuimica logo
    Targetmol
    + Info

    CD532 hydrochloride

    <p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>
    Color and Shape:Solid

    Ref: TM-T36932

  • Clofarabine-5'-triphosphate
    Targetmol
    + Info

    Clofarabine-5'-triphosphate

    CAS:
    <p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>
    Formula:C10H14ClFN5O12P3
    Color and Shape:Solid
    Molecular weight:543.62

    Ref: TM-T203136

  • CymitQuimica logo
    Targetmol
    + Info

    PROTAC MTP3 degrade-1

    <p>PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.</p>
    Formula:C44H38N6O8
    Color and Shape:Solid
    Molecular weight:778.27511

    Ref: TM-T207468

  • CymitQuimica logo
    Targetmol
    + Info

    N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine

    <p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H22N2O7
    Color and Shape:Solid
    Molecular weight:330.33

    Ref: TM-T75214

  • CDK5-IN-1
    Targetmol
    + Info

    CDK5-IN-1

    CAS:
    <p>CDK5-IN-1: Potent CDK5 inhibitor (&lt;10 nM) used in kidney disease research.</p>
    Formula:C24H25FN6O3S
    Color and Shape:Solid
    Molecular weight:496.56

    Ref: TM-T40263

  • Clofarabine-5'-diphosphate
    Targetmol
    + Info

    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64

    Ref: TM-T203181

  • Echistatin
    Targetmol
    + Info

    Echistatin

    CAS:
    <p>Potent αVβ3 integrin blocker, stops osteoclast binding &amp; bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>
    Formula:C217H341N71O74S9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5417.1

    Ref: TM-TP2098

  • CymitQuimica logo
    Targetmol
    + Info

    PAT-LM1

    <p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1103

  • α2β1 Integrin Ligand Peptide
    Targetmol
    + Info

    α2β1 Integrin Ligand Peptide

    CAS:
    <p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>
    Formula:C14H22N4O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:390.35

    Ref: TM-TP1484

  • CTP Synthetase-IN-1 Ammonium salt
    Targetmol
    + Info

    CTP Synthetase-IN-1 Ammonium salt

    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:529.56

    Ref: TM-T72505L

  • TAS-119
    Targetmol
    + Info

    TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36

    Ref: TM-T34787

  • SMS 121
    Targetmol
    + Info

    SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Formula:C20H21NO5
    Purity:98.29%
    Color and Shape:Soild
    Molecular weight:355.38

    Ref: TM-T205876

  • CymitQuimica logo
    Targetmol
    + Info

    Chrexanthomycin C

    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Color and Shape:Solid
    Molecular weight:636.51

    Ref: TM-T75527

  • 5'-O-DMT-N4-Bz-2'-F-dC
    Targetmol
    + Info

    5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Formula:C37H34FN3O7
    Color and Shape:Solid
    Molecular weight:651.68

    Ref: TM-T37137

  • CDK6/9-IN-1
    Targetmol
    + Info

    CDK6/9-IN-1

    CAS:
    <p>CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).</p>
    Formula:C22H25ClN8O
    Color and Shape:Solid
    Molecular weight:452.95

    Ref: TM-T40047

  • JAMM protein inhibitor 2 
    Targetmol
    + Info

    JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Formula:C21H26N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:338.44

    Ref: TM-T9892

  • 3'-Deoxyuridine-5'-triphosphate trisodium
    Targetmol
    + Info

    3'-Deoxyuridine-5'-triphosphate trisodium

    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08

    Ref: TM-T35658

  • SNX7
    Targetmol
    + Info

    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Formula:C15H14N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:238.28

    Ref: TM-T77613

  • JB300
    Targetmol
    + Info

    JB300

    CAS:
    <p>JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.</p>
    Formula:C43H45ClFN7O10S
    Color and Shape:Solid
    Molecular weight:906.375

    Ref: TM-T204223

  • 5'-O-DMT-PAC-dA
    Targetmol
    + Info

    5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74

    Ref: TM-T37139

  • CymitQuimica logo
    Targetmol
    + Info

    UnyLinker 12 TEA

    <p>UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.</p>
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655

    Ref: TM-TSW-00947

  • Gantofiban
    Targetmol
    + Info

    Gantofiban

    CAS:
    <p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>
    Formula:C21H29N5O6
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:447.48

    Ref: TM-T68078

  • 11H-Benzo[a]carbazole
    Targetmol
    + Info

    11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Formula:C16H11N
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:217.27

    Ref: TM-TN9686

  • CymitQuimica logo
    Targetmol
    + Info

    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Formula:C36H39ClN4O9S
    Color and Shape:Solid
    Molecular weight:738.21263

    Ref: TM-T207280

  • CymitQuimica logo
    Targetmol
    + Info

    GK13S

    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Color and Shape:Solid
    Molecular weight:390.44

    Ref: TM-T75182

  • CymitQuimica logo
    Targetmol
    + Info

    N7-Methyl-2'-O-(2-methoxyethyl) guanosine

    <p>N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H21N5O6
    Color and Shape:Solid
    Molecular weight:355.35

    Ref: TM-T75060

  • EFdA-TP
    Targetmol
    + Info

    EFdA-TP

    CAS:
    <p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>
    Formula:C12H15FN5O12P3
    Color and Shape:Solid
    Molecular weight:533.195

    Ref: TM-T41110

  • CCT241533 dihydrochloride
    Targetmol
    + Info

    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41

    Ref: TM-T36704

  • CymitQuimica logo
    Targetmol
    + Info

    5'-DMTr-3'dA(Bz)-methylphosphonami dite

    <p>5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoid</p>
    Formula:C45H51N6O6P
    Color and Shape:Solid
    Molecular weight:802.9

    Ref: TM-T75217