DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 958 products of "DNA Damage/DNA Repair"
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L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11KCC-07
CAS:<p>KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.</p>Formula:C14H11N3OSPurity:98.86% - 99.01%Color and Shape:SolidMolecular weight:269.32Tasquinimod
CAS:<p>Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.</p>Formula:C20H17F3N2O4Purity:99.22% - >99.99%Color and Shape:SolidMolecular weight:406.36SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56Ceralasertib
CAS:<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Formula:C20H24N6O2SPurity:98% - 99.99%Color and Shape:SolidMolecular weight:412.51Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Formula:C19H19N3O2Purity:99.22%Color and Shape:SolidMolecular weight:321.37Razoxane
CAS:<p>Razoxane is used as an antimitotic agent with immunosuppressive properties.</p>Formula:C11H16N4O4Purity:99.75%Color and Shape:SolidMolecular weight:268.27Darglitazone Sodium
CAS:<p>Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.</p>Formula:C23H21N2NaO4SColor and Shape:SolidMolecular weight:444.48BGP-15
CAS:<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Formula:C14H24Cl2N4O2Purity:98.17% - 99.89%Color and Shape:SolidMolecular weight:351.27KU60019
CAS:<p>Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.</p>Formula:C30H33N3O5SPurity:95.9% - 99.36%Color and Shape:SolidMolecular weight:547.67GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formula:C13H9ClN2O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:276.68RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Formula:C22H17F2N2·CH3O4SPurity:99.72%Color and Shape:SolidMolecular weight:458.48AZ20
CAS:<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Formula:C21H24N4O3SPurity:98% - 99.69%Color and Shape:SolidMolecular weight:412.51Rabdosiin
CAS:<p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>Formula:C36H30O16Purity:98.64% - 99.49%Color and Shape:SolidMolecular weight:718.61PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Formula:C16H14BrN5O4S·HClPurity:97.82%Color and Shape:SolidMolecular weight:488.74Topovale
CAS:<p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>Formula:C23H23N3O5Purity:99.94%Color and Shape:SolidMolecular weight:421.45JW 55
CAS:<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48Pixantrone hydrochloride
CAS:<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Formula:C17H20ClN5O2Color and Shape:SolidMolecular weight:361.83Tretazicar
CAS:<p>CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.</p>Formula:C9H8N4O5Purity:99.41% - 99.7%Color and Shape:SolidMolecular weight:252.18Coralyne chloride
CAS:<p>Coralyne chloride is a protoberberine with strong anticancer activity.</p>Formula:C22H22ClNO4Purity:98.88%Color and Shape:SolidMolecular weight:399.87NU6027
CAS:<p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>Formula:C11H17N5O2Purity:98.36%Color and Shape:SolidMolecular weight:251.29Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formula:C19H23ClFN3O4Purity:99.85% - 99.89%Color and Shape:SolidMolecular weight:411.86NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formula:C21H23NO4Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:353.41Thiomyristoyl
CAS:<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Formula:C34H51N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:581.85Genz-644282
CAS:<p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>Formula:C22H21N3O5Purity:97.49%Color and Shape:SolidMolecular weight:407.42Pentamidine
CAS:<p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>Formula:C19H24N4O2Purity:98.64% - 99.67%Color and Shape:Crystallizes As Colorless Plates From Water SolidMolecular weight:340.42TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Formula:C11H7NOSPurity:99.75%Color and Shape:SolidMolecular weight:201.24AZD-2461
CAS:<p>AZD2461 is a novel PARP inhibitor.</p>Formula:C22H22FN3O3Purity:98% - 99.87%Color and Shape:SolidMolecular weight:395.43Clomesone
CAS:<p>Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.</p>Formula:C4H9ClO5S2Purity:99%Color and Shape:SolidMolecular weight:236.69Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formula:C31H32N8O5Purity:98%Color and Shape:SolidMolecular weight:596.64TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formula:C72H66N8O12S4Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:1363.6UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29SRT1720 hydrochloride
CAS:<p>SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).</p>Formula:C25H24ClN7OSPurity:98% - 99.93%Color and Shape:SolidMolecular weight:506.22KU-57788
CAS:<p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>Formula:C25H19NO3SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:413.49EDO-S101
CAS:<p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>Formula:C19H28Cl2N4O2Purity:98.02% - 99.44%Color and Shape:SolidMolecular weight:415.36SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3PARP1-IN-5 dihydrochloride
CAS:<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formula:C25H26Cl2N2O5SPurity:98.01%Color and Shape:SolidMolecular weight:537.46Furegrelate
CAS:<p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>Formula:C15H11NO3Purity:99.71%Color and Shape:SolidMolecular weight:253.25AZ32
CAS:<p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>Formula:C20H16N4OPurity:98.68% - 99.68%Color and Shape:SolidMolecular weight:328.37AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formula:C26H22N6O2Purity:99.18% - 99.86%Color and Shape:SolidMolecular weight:450.49DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24Bendamustine
CAS:<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Formula:C16H21Cl2N3O2Purity:≥98%Color and Shape:SolidMolecular weight:358.26γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9VE-821
CAS:<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formula:C18H16N4O3SPurity:97.19% - 99.97%Color and Shape:SolidMolecular weight:368.41Prulifloxacin
CAS:<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formula:C21H20FN3O6SPurity:99.47%Color and Shape:Yellow Or Slightly Yellow PowerMolecular weight:461.46Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H21ClFN3O4Purity:99.78% - 99.98%Color and Shape:SolidMolecular weight:397.8Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formula:C9H13N5NaO4Purity:99.93%Color and Shape:SolidMolecular weight:278.22
