DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(422 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 958 products of "DNA Damage/DNA Repair"
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Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formula:C20H20N8Na2O5Purity:99.77% - 99.96%Color and Shape:SolidMolecular weight:498.49-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formula:C20H16N2O5Purity:98.28%Color and Shape:SolidMolecular weight:364.35Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H21ClFN3O4Purity:99.78% - 99.98%Color and Shape:SolidMolecular weight:397.8PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Formula:C14H16ClN3O4S2Purity:97.72%Color and Shape:SolidMolecular weight:389.88Xanthosine 5'-monophosphate sodium salt
CAS:<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formula:C10H11N4Na2O9PPurity:99% - 99.77%Color and Shape:SolidMolecular weight:408.17Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formula:C9H13N5NaO4Purity:99.93%Color and Shape:SolidMolecular weight:278.22Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formula:C10H9AgN4O2SPurity:99.04% - 99.58%Color and Shape:SolidMolecular weight:357.14AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formula:C18H20N8O2Purity:99.03% - 99.85%Color and Shape:SolidMolecular weight:380.4AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formula:C22H24N4O4Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:408.451-Oleoyl lysophosphatidic acid sodium
CAS:<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Formula:C21H40O7P·NaPurity:98.75% - 99.24%Color and Shape:SolidMolecular weight:458.51LMK-235
CAS:<p>LMK-235 is a potent HDAC inhibitor, and is used in cancer research.</p>Formula:C15H22N2O4Purity:98.18% - 99.68%Color and Shape:SolidMolecular weight:294.35MK-4827 Racemate
CAS:<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Formula:C19H20N4OPurity:99.86%Color and Shape:SolidMolecular weight:320.39Altretamine hydrochloride
CAS:<p>Altretamine hydrochloride is an alkylating antineoplastic agent.</p>Formula:C9H19ClN6Color and Shape:SolidMolecular weight:246.74Ensulizole
CAS:<p>Ensulizole, a water-soluble UV absorber, damages DNA by generating ROS under UV light, and absorbs UVB and some UVA.</p>Formula:C13H10N2O3SPurity:99.79%Color and Shape:White To Pale Beige Solid PowderMolecular weight:274.30Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formula:C19H23ClFN3O4Purity:99.85% - 99.89%Color and Shape:SolidMolecular weight:411.86EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C9H13N3O6Purity:99.14% - 99.73%Color and Shape:SolidMolecular weight:259.22Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formula:C20H15N3O6Purity:97.54%Color and Shape:Yellow Amorphous PowderMolecular weight:393.352',3',5'-triacetyl-5-Azacytidine
CAS:<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Formula:C14H18N4O8Purity:98.34%Color and Shape:SolidMolecular weight:370.31CXD101
CAS:<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Formula:C24H29N5OPurity:99.82%Color and Shape:SolidMolecular weight:403.52SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formula:C13H9ClN2O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:276.68M344
CAS:<p>M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.</p>Formula:C16H25N3O3Purity:98.18%Color and Shape:SolidMolecular weight:307.39NU1025
CAS:<p>NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.</p>Formula:C9H8N2O2Purity:99.86%Color and Shape:SolidMolecular weight:176.17AG14361
CAS:<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Formula:C19H20N4OPurity:98.7% - 99.93%Color and Shape:SolidMolecular weight:320.391,4-Naphthoquinone
CAS:<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Formula:C10H6O2Purity:99.24% - 99.56%Color and Shape:SolidMolecular weight:158.15CM-579 trihydrochloride
<p>CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.</p>Formula:C29H43Cl3N4O3Color and Shape:SolidMolecular weight:602.04NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Formula:C17H15NO3Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:281.31SirReal2
CAS:<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Formula:C22H20N4OS2Purity:98.96% - 99.75%Color and Shape:SolidMolecular weight:420.55PI-3065
CAS:<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Formula:C27H31FN6OSPurity:99.84% - ≥95%Color and Shape:SolidMolecular weight:506.64ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32Palifosfamide tromethamine
CAS:<p>Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.</p>Formula:C8H22Cl2N3O5PColor and Shape:SolidMolecular weight:342.16Azemiglitazone
CAS:<p>Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.</p>Formula:C19H17NO5SPurity:98.29% - 99.6%Color and Shape:SolidMolecular weight:371.41NMS-P118
CAS:<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Formula:C20H24F3N3O2Purity:98.79%Color and Shape:SolidMolecular weight:395.42Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Formula:C9H12N2O5Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:228.2Thymidine
CAS:<p>Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.</p>Formula:C10H14N2O5Purity:99.64% - 99.86%Color and Shape:White To Off-White Solid CrystallineMolecular weight:242.23T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Formula:C12H8ClN3O3Purity:98.25% - 99.98%Color and Shape:SolidMolecular weight:277.66SW-100
CAS:<p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.</p>Formula:C17H17ClN2O2Purity:98.34% - 98.47%Color and Shape:SolidMolecular weight:316.78Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formula:C22H24N6OSPurity:98.56% - 99.49%Color and Shape:SolidMolecular weight:420.53Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45L-778123 hydrochloride
CAS:<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Formula:C22H21Cl2N5OPurity:93.93% - 98.51%Color and Shape:SolidMolecular weight:442.34Prulifloxacin
CAS:<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formula:C21H20FN3O6SPurity:99.47%Color and Shape:Yellow Or Slightly Yellow PowerMolecular weight:461.46Ceralasertib
CAS:<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Formula:C20H24N6O2SPurity:98% - 99.99%Color and Shape:SolidMolecular weight:412.51VE-821
CAS:<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formula:C18H16N4O3SPurity:97.19% - 99.97%Color and Shape:SolidMolecular weight:368.41Indotecan
CAS:<p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>Formula:C26H26N2O7Purity:97% - 98%Color and Shape:SolidMolecular weight:478.49γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9Thiomyristoyl
CAS:<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Formula:C34H51N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:581.85AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Formula:C23H13Cl2N3O2Purity:98.31%Color and Shape:SolidMolecular weight:434.27Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formula:C10H12O2Purity:99.49% - 99.67%Color and Shape:SolidMolecular weight:164.2UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Formula:C16H13N3Purity:98.31%Color and Shape:SolidMolecular weight:247.29
