Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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DDO-7263
CAS:<p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>Formula:C14H9F2N3OPurity:99.85%Color and Shape:SolidMolecular weight:273.24Keap1-Nrf2-IN-16
CAS:<p>Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.</p>Formula:C73H114N16O26Color and Shape:SolidMolecular weight:1631.78AMPCP
CAS:<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Formula:C11H15N5Na2O9P2Color and Shape:SolidMolecular weight:469.194-CPPC
CAS:<p>4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.</p>Formula:C14H9NO6Purity:97.50% - 98.03%Color and Shape:SolidMolecular weight:287.22Fenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Formula:C22H17ClN2O5Color and Shape:SolidMolecular weight:424.83TLR8 agonist 5
CAS:<p>TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.</p>Formula:C31H40N6O5Color and Shape:SolidMolecular weight:576.69PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formula:C22H24N4O3SPurity:98.09% - 99.64%Color and Shape:SolidMolecular weight:424.52ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Formula:C14H10N4Purity:98.55%Color and Shape:SolidMolecular weight:234.26Glabrescone C
CAS:<p>Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.</p>Formula:C19H22O7Color and Shape:SolidMolecular weight:362.37TLR7/8 agonist 8
CAS:<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Formula:C24H30N6OColor and Shape:SolidMolecular weight:418.53PF 184
CAS:<p>IKKβ inhibitor</p>Formula:C32H32ClFN6O4Purity:98%Color and Shape:SolidMolecular weight:619.09NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Formula:C12H13ClO3Purity:99.64%Color and Shape:SolidMolecular weight:240.68IKK-IN-4
CAS:<p>IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].</p>Formula:C18H19N5SColor and Shape:SolidMolecular weight:337.44DNA polymerase-IN-1
CAS:<p>DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.</p>Formula:C10H7ClO4Purity:99.16%Color and Shape:SolidMolecular weight:226.61TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Formula:C21H22N4O2Color and Shape:SolidMolecular weight:362.42Arginase inhibitor 1
CAS:<p>Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).</p>Formula:C13H27BN2O4Color and Shape:SolidMolecular weight:286.18(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Formula:C27H34N6O2Color and Shape:SolidMolecular weight:474.6Factor B-IN-2
CAS:<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Formula:C25H32N2O4Color and Shape:SolidMolecular weight:424.53STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Formula:C47H67NO9S2Purity:98%Color and Shape:SolidMolecular weight:854.17Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Formula:C24H19FN2O3SPurity:98%Color and Shape:SolidMolecular weight:434.48RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46TLR4 agonist-1
CAS:<p>TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1</p>Formula:C81H158N3O15PColor and Shape:SolidMolecular weight:1445.11hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Formula:C18H23F2N3Purity:98%Color and Shape:SolidMolecular weight:319.39Aminoguanidine hemisulfate
CAS:<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Formula:CH6N4H2SO4Purity:98%Color and Shape:SolidMolecular weight:123.115IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Formula:C48H50I2N2O5Purity:98%Color and Shape:SolidMolecular weight:988.73GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Formula:C19H20N2O4Purity:99.69%Color and Shape:SolidMolecular weight:340.37TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Formula:C27H37N7O2Purity:>99.99%Color and Shape:SolidMolecular weight:491.63Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Formula:C12H12N2O3SPurity:98%Color and Shape:SolidMolecular weight:264.3NLRP3-IN-21
CAS:<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Formula:C20H13Cl2F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:529.32MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8IRAK4-IN-28
CAS:<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Formula:C27H31N9O3Purity:98%Color and Shape:SolidMolecular weight:529.59CCT374705
CAS:<p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>Formula:C21H18ClF3N4O2Color and Shape:SolidMolecular weight:450.84Galectin-3 antagonist 2
CAS:<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Formula:C22H23NO10Purity:98%Color and Shape:SolidMolecular weight:461.42BF738735
CAS:<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Formula:C21H19FN4O3SPurity:90%Color and Shape:SolidMolecular weight:426.46RIPK2-IN-3
CAS:<p>RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.</p>Formula:C25H22N4O2Purity:99.57%Color and Shape:SolidMolecular weight:410.47h-NTPDase-IN-3
CAS:<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Formula:C16H10N4SPurity:98.24%Color and Shape:SolidMolecular weight:290.34NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Formula:C24H27ClF3N5O4SColor and Shape:SolidMolecular weight:574.02(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Formula:C20H26O4Purity:98%Color and Shape:SolidMolecular weight:330.42Antitumor agent-114
CAS:<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Formula:C39H50F2N10O13P2Purity:98%Color and Shape:SolidMolecular weight:966.82NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Formula:C20H20O5Purity:98%Color and Shape:SolidMolecular weight:340.37BI 7446
CAS:<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Formula:C20H22FN9O10P2S2Purity:98%Color and Shape:SolidMolecular weight:693.52CD73-IN-6
CAS:<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Formula:C20H15N7O2Color and Shape:SolidMolecular weight:385.38FCE-27164
CAS:<p>FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.</p>Formula:C45H34N10Na6O23S6Purity:96.04%Color and Shape:SolidMolecular weight:1413.11Dexamethasone palmitate
CAS:<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Formula:C38H59FO6Purity:99.28%Color and Shape:SolidMolecular weight:630.87CD73-IN-10
CAS:<p>CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.</p>Formula:C15H13F2N5O2Color and Shape:SolidMolecular weight:333.29TLR7 agonist 14
CAS:<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Formula:C29H36N6O3Color and Shape:SolidMolecular weight:516.63BD-AcAc 2
CAS:<p>BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.</p>Formula:C8H16O4Purity:99.62%Color and Shape:SolidMolecular weight:176.21NLRP3-IN-18
CAS:<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Formula:C19H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:339.82Friluglanstat
CAS:<p>Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].</p>Formula:C25H20ClF3N4O3Purity:98%Color and Shape:SolidMolecular weight:516.9CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Formula:C19H24N6O3Color and Shape:SolidMolecular weight:384.43MAPK-IN-1
CAS:<p>MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.</p>Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34NLRP3-IN-22
CAS:<p>NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].</p>Formula:C19H12F3NO4SPurity:98%Color and Shape:SolidMolecular weight:407.36W-54011
CAS:<p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>Formula:C30H37ClN2O2Purity:96.8%Color and Shape:SolidMolecular weight:493.08OATD-02
CAS:<p>OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory</p>Formula:C12H25BN2O4Purity:98%Color and Shape:SolidMolecular weight:272.15Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Formula:C39H35N3O12S2Color and Shape:SolidMolecular weight:801.845J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Formula:C16H12N2O3SPurity:96.12%Color and Shape:SolidMolecular weight:312.34JT002
CAS:<p>JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)</p>Formula:C20H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:432.49Nitric oxide production-IN-1
CAS:<p>Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.</p>Formula:C33H52O15Purity:98%Color and Shape:SolidMolecular weight:688.76TMV-IN-2
CAS:<p>TMV-IN-2, a chalcone, inhibits TMV with an EC50 of 89.9 μg/mL, used in infection and tumor studies.</p>Formula:C27H23FO4Color and Shape:SolidMolecular weight:430.473'-Azido-3'-deoxy-5-methylcytidine
CAS:<p>3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related</p>Formula:C10H14N6O4Purity:99.55%Color and Shape:SolidMolecular weight:282.26Ro26-4550
CAS:<p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>Formula:C26H30N4O3Purity:98%Color and Shape:SolidMolecular weight:446.54Keap1-Nrf2-IN-6
<p>Keap1-Nrf2-IN-6 is a potent, selective inhibitor of the Keap1-Nrf2 protein−protein interaction (PPI), demonstrating an inhibitory concentration (IC50) of 41 nM</p>Formula:C30H34N4O8SColor and Shape:SolidMolecular weight:610.68PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Formula:C32H32ClFN6O4Color and Shape:SolidMolecular weight:619.09RPR-106541
CAS:<p>RPR-106541, a GR agonist, is used potentially for the treatment of asthma.</p>Formula:C24H34F2O4SColor and Shape:SolidMolecular weight:456.59IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Formula:C18H18ClNSPurity:99.77%Color and Shape:SolidMolecular weight:315.86TMV-IN-4
CAS:<p>TMV-IN-4, a TMV inhibitor, enhances plant defense and TMV resilience by interacting with helicase, increasing peroxidase and SOD activity.</p>Formula:C18H21NO4Color and Shape:SolidMolecular weight:315.36CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Formula:C16H23ClN5O7PPurity:98.61%Color and Shape:SolidMolecular weight:463.81(R)-MALT1-IN-7
CAS:<p>(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.</p>Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45Bay 65-1942 (R form)
CAS:<p>Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.</p>Formula:C22H25N3O4Purity:98%Color and Shape:SolidMolecular weight:395.45BW 755C
CAS:<p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>Formula:C10H10F3N3Purity:96.52%Color and Shape:SolidMolecular weight:229.2ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Formula:C27H28Cl2N4O5SPurity:98%Color and Shape:SolidMolecular weight:591.51CD73-IN-11
CAS:<p>CD73-IN-11 is a potent inhibitor used to prepare medication for cancer by blocking adenosine production, which fosters tumor growth.</p>Formula:C14H10F3N5O2Color and Shape:SolidMolecular weight:337.26STING Agonist D61
CAS:<p>STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline</p>Formula:C29H29F3N8O4Color and Shape:SolidMolecular weight:610.60GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Formula:C21H24F3N7OPurity:99.86% - 99.86%Color and Shape:SolidMolecular weight:447.46Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Formula:C27H43N3O11Color and Shape:SolidMolecular weight:585.64Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Formula:C21H19F3N4O6SPurity:99.18%Color and Shape:SolidMolecular weight:512.46Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Formula:C10H16N4Na2O6Purity:98%Color and Shape:SolidMolecular weight:334.24Dimethoxycurcumin
CAS:<p>Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.</p>Formula:C23H24O6Purity:99.87%Color and Shape:SolidMolecular weight:396.43MALT1-IN-9
CAS:<p>MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.</p>Formula:C16H12ClF3N6OColor and Shape:SolidMolecular weight:396.75Nrf2-IN-1
CAS:<p>Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).</p>Formula:C21H22ClN3O2Purity:95.00% - 99.68%Color and Shape:SolidMolecular weight:383.87Glutathione ethyl ester
CAS:<p>Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels.</p>Formula:C12H21N3O6SPurity:98.958%Color and Shape:SoildMolecular weight:335.38Nrf2 activator-7
CAS:<p>Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.</p>Formula:C35H32N2O11S2Color and Shape:SolidMolecular weight:720.77STING agonist-3
CAS:<p>STING agonist-3: non-nucleotide, selective, anti-tumor with pEC50=7.5, pIC50=9.5, could enhance cancer therapy.</p>Formula:C37H42N12O6Purity:98%Color and Shape:SolidMolecular weight:750.81COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Formula:C20H32O6Color and Shape:SolidMolecular weight:368.5TIM-3-IN-2
CAS:<p>TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.</p>Formula:C25H23N3O6Purity:98.93%Color and Shape:SolidMolecular weight:461.47TLR8 agonist 6
CAS:<p>Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.</p>Formula:C19H29N7O2Color and Shape:SolidMolecular weight:387.48Lobenzarit sodium
CAS:<p>Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.</p>Formula:C14H8ClNNa2O4Purity:99.35%Color and Shape:SolidMolecular weight:335.65IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Formula:C21H21N5O4SPurity:98.86%Color and Shape:SolidMolecular weight:439.49CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Formula:C15H19NO3Purity:98%Color and Shape:SolidMolecular weight:261.323M-011
CAS:<p>3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.</p>Formula:C18H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:391.49Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72Stobadine
CAS:<p>Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.</p>Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Formula:C21H22N4O2SPurity:98%Color and Shape:SolidMolecular weight:394.49HBF-0259
CAS:<p>HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.</p>Formula:C16H12Cl2FN5Purity:98.07% - 99.42%Color and Shape:SolidMolecular weight:364.2TLR7 agonist 4
CAS:<p>TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).</p>Formula:C23H34N6O3Color and Shape:SolidMolecular weight:442.55NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Formula:C23H27N3O4Purity:99.67%Color and Shape:SolidMolecular weight:409.48C5aR-IN-1
CAS:<p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>Formula:C36H39F4N3O2Color and Shape:SolidMolecular weight:621.71
