Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3035 products of "Immunology and Inflammation"
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Fudosteine
CAS:<p>Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.</p>Formula:C6H13NO3SPurity:99.59%Color and Shape:Off-White CrystallineMolecular weight:179.24Erdosteine
CAS:<p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>Formula:C8H11NO4S2Purity:99.43% - 99.94%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:249.31(3E,4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one
CAS:Formula:C20H30O5Purity:98%Color and Shape:SolidMolecular weight:350.4492S-Nitroso-N-acetyl-DL-penicillamine
CAS:<p>S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .</p>Formula:C7H12N2O4SPurity:97.42% - >99.99%Color and Shape:Green Crystalline SolidMolecular weight:220.25GSK3145095
CAS:<p>GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.</p>Formula:C20H17F2N5O2Purity:99.50%Color and Shape:SolidMolecular weight:397.38TBK1/IKKε-IN-2
CAS:<p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>Formula:C26H27N5O3Purity:98.89%Color and Shape:SolidMolecular weight:457.524-Imidazoleacetic acid HCl
CAS:Formula:C5H7ClN2O2Purity:97%Color and Shape:SolidMolecular weight:162.5743Emapalumab
CAS:<p>Emapalumab (NI-0501), an IgG1 antibody, blocks interferon gamma, curbing inflammation. Used in HLH studies, it binds IFN-γ tightly (Kd=1.4 pM).</p>Purity:SDS-PAGE:95% SEC-HPLC:97.56%Color and Shape:LiquidMolecular weight:145.22 kDaTheralizumab
CAS:<p>Theralizumab (TGN1412) is a monoclonal antibody for treating leukemia and arthritis by stimulating T cells.</p>Purity:95%Color and Shape:LiquidAdrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formula:C9H11NO3·HClPurity:99.94%Color and Shape:SolidMolecular weight:217.65Sabatolimab
CAS:<p>Sabatolimab (MBG453) is a humanized IgG4 antibody that inhibits TIM-3 to modulate immunity and shows promise as an immunosuppressant.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145 kDa (average)4-Hydroxyantipyrine
CAS:<p>4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.</p>Formula:C11H12N2O2Purity:99.85%Color and Shape:SolidMolecular weight:204.23Suxibuzone
CAS:<p>Suxibuzone is a prodrug for joint/muscle pain relief in horses, derived from phenylbutazone.</p>Formula:C24H26N2O6Purity:99.85%Color and Shape:SolidMolecular weight:438.47N-Demethylricinine
CAS:<p>N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor.</p>Formula:C7H6N2O2Purity:99.11%Color and Shape:SolidMolecular weight:150.13Oxiracetam
CAS:<p>Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.</p>Formula:C6H10N2O3Purity:99.67%Color and Shape:White Crystalline PowderMolecular weight:158.16Salsalate
CAS:<p>Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic</p>Formula:C14H10O5Purity:99.76%Color and Shape:SolidMolecular weight:258.23BPK-29 hydrochloride
CAS:<p>"BPK-29 hydrochloride targets NR0B1, altering C274 and hinders KEAP1-mutant cancer cell growth."</p>Formula:C26H33Cl2N3O3Purity:99.06%Color and Shape:SolidMolecular weight:506.46Metacetamol
CAS:<p>Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.</p>Formula:C8H9NO2Purity:99.76% - 99.90%Color and Shape:Physical Description Light Gray Solid (Ntp 1992)Molecular weight:151.166-Methoxy-2-naphthoic acid
CAS:<p>6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.</p>Formula:C12H10O3Purity:99.25%Color and Shape:White To Off-White Powder Crystals Crystalline Powder And/Or ChunksMolecular weight:202.21Cobolimab
CAS:<p>Cobolimab (TSR-022) is a TIM-3 antibody with IC50 of 0.4464 nM, showing antitumor effects in melanoma and liver cancer studies.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:142.84 kDaTheophylline
CAS:<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Formula:C7H8N4O2Purity:99.65% - 99.98%Color and Shape:White Solid PowderMolecular weight:180.16SM-276001
CAS:<p>SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.</p>Formula:C16H21N7OPurity:99.91%Color and Shape:SolidMolecular weight:327.38Baicalin
CAS:<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Formula:C21H18O11Purity:90.08% - 99.32%Color and Shape:Yellow PowderMolecular weight:446.36Atazanavir
CAS:<p>Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.</p>Formula:C38H52N6O7Purity:98% - 99.95%Color and Shape:Crystalline SolidMolecular weight:704.86Articaine hydrochloride
CAS:<p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>Formula:C13H21ClN2O3SPurity:99.76%Color and Shape:White Crystalline PowderMolecular weight:320.84CU-T12-9
CAS:<p>CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).</p>Formula:C17H13F3N4O2Purity:99.84%Color and Shape:SolidMolecular weight:362.31Brodalumab
CAS:<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Purity:98.3%Color and Shape:LiquidMolecular weight:144.06 kDaRisankizumab
CAS:<p>Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.</p>Purity:SDS-PAGE:95.3%;SEC-HPLC:98.3%Color and Shape:LiquidMolecular weight:145.85 kDaHistamine dihydrochloride
CAS:Formula:C5H11Cl2N3Purity:96%Color and Shape:SolidMolecular weight:184.0669Ibritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Purity:96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Color and Shape:Odour LiquidAChE-IN-82
<p>AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.</p>Formula:C21H18N4O5S2Color and Shape:SolidMolecular weight:470.52Coltuximab
<p>Coltuximab is a humanized anti-CD19 antibody that can be used to synthesize ADC compounds (Coltuximab Ravtansine).</p>Purity:95.3% (SDS-PAGE); 98.6% (SEC-HPLC) - 95.3% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:Odour LiquidSjDX5-271
CAS:<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Formula:C137H215N47O49SColor and Shape:SolidMolecular weight:3336.52ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Purity:97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:Odour LiquidNemvaleukin alfa
CAS:<p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>Purity:98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)Color and Shape:LiquidNrf2/HO-1 activator 3
<p>Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.</p>Formula:C27H26N2O6Color and Shape:SolidMolecular weight:474.51NBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formula:C62H88N14O20Color and Shape:SolidMolecular weight:1349.44(R)-Zadavotide guraxetan
CAS:<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Formula:C63H92IN11O23Color and Shape:SolidMolecular weight:1498.37Simlukafusp alfa
CAS:<p>Simlukafusp alfa (FAP-IL2v) is a tumor-targeting immune cytokine, a human IgG1 antibody with antitumor activity and immunostimulatory properties.</p>Purity:97.3% (SDS-PAGE); 94.3% (SEC-HPLC) - 97.3% (SDS-PAGE); 94.3% (SEC-HPLC)Color and Shape:Liquid4-ACETAMIDOANTIPYRINE
CAS:<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C13H15N3O2Color and Shape:SolidMolecular weight:245.28STING agonist-17
CAS:<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formula:C43H53N13O8Color and Shape:SolidMolecular weight:879.96C2 Ceramide (d14:1/2:0)
CAS:<p>C2 Ceramide (d14:1/2:0), a bioactive sphingolipid, causes lipotoxic cardiomyopathy when fed to Drosophila at 100 μM.</p>Formula:C16H31NO3Color and Shape:SolidMolecular weight:285.42C12-rrw-NH2
<p>C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.</p>Formula:C35H58N10O5Color and Shape:SolidMolecular weight:698.9KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Color and Shape:Odour LiquidPMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formula:C47H63F3N10O8Color and Shape:SolidMolecular weight:953.06Tetrachlorohydroquinone
CAS:<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Formula:C6H2Cl4O2Color and Shape:SolidMolecular weight:247.89FITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidPF-06426779
CAS:<p>PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.</p>Formula:C17H18FN3O4Color and Shape:SolidMolecular weight:347.346Ladanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4Benz-AP
CAS:<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formula:C20H13NO2Color and Shape:SolidMolecular weight:299.32
