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PPAR

PPAR

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.

Found 164 products of "PPAR"

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  • Cloxiquine

    CAS:
    <p>Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.</p>
    Formula:C9H6ClNO
    Purity:99.82% - 99.87%
    Color and Shape:Light Yellow Crystals
    Molecular weight:179.6
  • MA-0204

    CAS:
    <p>MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,</p>
    Formula:C25H27F3N2O4
    Purity:97.8%
    Color and Shape:Solid
    Molecular weight:476.49
  • Candesartan

    CAS:
    <p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>
    Formula:C24H20N6O3
    Purity:98.3% - 99.55%
    Color and Shape:Colorless Solid Crystalline
    Molecular weight:440.47
  • Retinoic acid

    CAS:
    <p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>
    Formula:C20H28O2
    Purity:97.21% - 99.6%
    Color and Shape:Yellow-Orange Powder
    Molecular weight:300.44
  • Clofibric acid

    CAS:
    <p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>
    Formula:C10H11ClO3
    Purity:99.47% - 99.8%
    Color and Shape:Pale Yellow Solid
    Molecular weight:214.65
  • GED-0507-34 Levo

    CAS:
    <p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>
    Formula:C10H13NO3
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:195.22
  • Fenofibric acid

    CAS:
    <p>Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.</p>
    Formula:C17H15ClO4
    Purity:99.36%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:318.75
  • NSC-87877

    CAS:
    <p>NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.</p>
    Formula:C19H13N3O7S2
    Purity:97.35%
    Color and Shape:Solid
    Molecular weight:459.45
  • Bezafibrate

    CAS:
    <p>Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES.</p>
    Formula:C19H20ClNO4
    Purity:99.56% - 99.82%
    Color and Shape:Solid
    Molecular weight:361.82
  • Muraglitazar

    CAS:
    <p>Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.</p>
    Formula:C29H28N2O7
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:516.54
  • LY518674

    CAS:
    <p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>
    Formula:C23H27N3O4
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:409.48
  • EHP-101

    CAS:
    <p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>
    Formula:C28H35NO3
    Purity:98.36%
    Color and Shape:Solid
    Molecular weight:433.58
  • NTP42

    CAS:
    <p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>
    Formula:C25H23F2N3O5S
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:515.53
  • Gemfibrozil

    CAS:
    <p>Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.</p>
    Formula:C15H22O3
    Purity:99.53% - 99.88%
    Color and Shape:Crystals From Hexane Solid
    Molecular weight:250.33
  • Rosiglitazone maleate

    CAS:
    <p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>
    Formula:C22H23N3O7S
    Purity:99.33% - 99.51%
    Color and Shape:Off-White Solid
    Molecular weight:473.50
  • Anandamide

    CAS:
    <p>Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also</p>
    Formula:C22H37NO2
    Purity:95.037% - 99.22%
    Color and Shape:Light Yellow Oil
    Molecular weight:347.53
  • Oleoylethanolamide

    CAS:
    <p>Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.</p>
    Formula:C20H39NO2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:325.53
  • Daidzein

    CAS:
    <p>Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.</p>
    Formula:C15H10O4
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:254.24
  • Fenofibrate

    CAS:
    <p>Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.</p>
    Formula:C20H21ClO4
    Purity:99.13% - 99.95%
    Color and Shape:Crystals From Isopropanol Solid
    Molecular weight:360.83
  • Mifobate

    CAS:
    <p>Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂,可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性,IC50为140 μM,具有抗肥胖和抗糖尿病作用。</p>
    Formula:C11H17ClO7P2
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:358.65
  • 5-Aminosalicylic Acid

    CAS:
    <p>5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!</p>
    Formula:C7H7NO3
    Purity:98.88% - 99.49%
    Color and Shape:Purplish-Tan Solid Powder
    Molecular weight:153.14
  • Pioglitazone hydrochloride

    CAS:
    <p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>
    Formula:C19H20N2O3S·HCl
    Purity:99.64% - >99.99%
    Color and Shape:White Crystals Or Crystalline Powder
    Molecular weight:392.90
  • MK-0533

    CAS:
    <p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>
    Formula:C28H24F3NO6
    Purity:99.03%
    Color and Shape:Soild
    Molecular weight:527.49
  • GW7647

    CAS:
    <p>GW 7647 is an effective and highly selective PPARα agonist. GW 7647 can reduce the production of nitric oxide in macrophages. Cost-effective and quality-assured.</p>
    Formula:C29H46N2O3S
    Purity:99.3% - 99.34%
    Color and Shape:Solid
    Molecular weight:502.75
  • Pioglitazone

    CAS:
    <p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>
    Formula:C19H20N2O3S
    Purity:95% - 99.57%
    Color and Shape:White Powder
    Molecular weight:356.44
  • Arhalofenate

    CAS:
    <p>Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.</p>
    Formula:C19H17ClF3NO4
    Purity:98.97%
    Color and Shape:Solid
    Molecular weight:415.79
  • β-Amyrone

    CAS:
    <p>beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.</p>
    Formula:C30H48O
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:424.7
  • Magnolol

    CAS:
    <p>Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.</p>
    Formula:C18H18O2
    Purity:99.49%
    Color and Shape:A Bioactive Compound Found In The Bark Of The Houpu Magnolia
    Molecular weight:266.33
  • WAY-620472

    CAS:
    <p>WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.</p>
    Formula:C23H21N5OS
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:415.51
  • Nuclear Receptor Compound Library


    <p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>
    Color and Shape:Odour Solid
  • Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-

    CAS:
    <p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>
    Formula:C24H23NO5S
    Purity:99.59%
    Color and Shape:Soild
    Molecular weight:437.51
  • PPAR agonist 6


    <p>PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].</p>
    Color and Shape:Odour Solid
  • SP4f


    <p>SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • Sulotroban potassium


    <p>Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.</p>
    Formula:C16H16KNO5S
    Purity:98.02%
    Color and Shape:Soild
    Molecular weight:373.46
  • Lipid Metabolism Compound Library


    <p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>
    Color and Shape:Odour Solid
  • 8-iso Prostaglandin F1β

    CAS:
    <p>8-iso Prostaglandin F1β,inducet vasoconstrictor effects in (PA), (PV) and (MA) through the activation of TXA2R, tyrosine kinase and Rho kinase.</p>
    Formula:C20H36O5
    Color and Shape:Solid
    Molecular weight:356.5
  • 8-iso Prostaglandin F1α

    CAS:
    <p>8-iso Prostaglandin F1α induces vasoconstrictor effects in (PA),(PV) and (MA) through activation of TXA2R, tyrosine kinases and Rho kinases.</p>
    Formula:C20H36O5
    Color and Shape:Solid
    Molecular weight:356.5
  • Anti-osteoporosis agent-10


    <p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>
    Color and Shape:Odour Solid
  • SP4e


    <p>SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.</p>
    Formula:C22H17ClN2O2S2
    Purity:99.79%
    Color and Shape:Soild
    Molecular weight:440.97
  • (±)-CBCQ

    CAS:
    <p>(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).</p>
    Formula:C21H28O3
    Color and Shape:Solid
    Molecular weight:328.45
  • CC618

    CAS:
    <p>CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.</p>
    Formula:C20H15F6N3O3S2
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:523.47
  • MCC-555

    CAS:
    <p>MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.</p>
    Formula:C21H16FNO3S
    Purity:99.07% - 99.82%
    Color and Shape:Solid
    Molecular weight:381.42
  • Sulotroban

    CAS:
    <p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>
    Formula:C16H17NO5S
    Purity:98.86% - 99.88%
    Color and Shape:Solid
    Molecular weight:335.37
  • AZD-9574

    CAS:
    <p>AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.</p>
    Formula:C21H22F2N6O2
    Purity:98.46% - 99.39%
    Color and Shape:Solid
    Molecular weight:428.44
  • E0924G

    CAS:
    <p>E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.</p>
    Formula:C12H12N2O3
    Color and Shape:Solid
    Molecular weight:232.24
  • Anti-obesity agent 1


    <p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>
    Formula:C21H22N2O6
    Color and Shape:Solid
    Molecular weight:398.409
  • PPARγ agonist 15


    <p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>
    Formula:C21H16N4O3S2
    Color and Shape:Solid
    Molecular weight:436.51
  • PPARγ agonist 16

    CAS:
    <p>PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.</p>
    Formula:C19H14BrNO4S
    Color and Shape:Solid
    Molecular weight:432.29
  • Mavodelpar free acid hydrochloride


    <p>Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.</p>
    Formula:C31H31ClFNO5
    Purity:98.13%
    Color and Shape:Soild
    Molecular weight:552.03
  • CUDA

    CAS:
    <p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>
    Formula:C19H36N2O3
    Purity:97.585%
    Color and Shape:Solid
    Molecular weight:340.5
  • GW590735

    CAS:
    <p>GW590735: PPARα agonist, EC50=4 nM, &gt;500x selective over PPARδ/γ, for dyslipidemia research.</p>
    Formula:C23H21F3N2O4S
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:478.48
  • PPARγ-IN-3


    <p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>
    Formula:C23H28FN7O3
    Color and Shape:Solid
    Molecular weight:469.51
  • GQ-16

    CAS:
    <p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>
    Formula:C19H16BrNO3S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:418.3
  • CP-868388 free base

    CAS:
    <p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>
    Formula:C26H33NO5
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:439.54
  • PPAR α/PPARA Protein, Human, Recombinant (His)


    <p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:31.36 kDa (predicted)
  • PPAR α/PPARA Protein, Mouse, Recombinant (His)


    <p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:31.49 kDa (predicted)
  • Balaglitazone

    CAS:
    <p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>
    Formula:C20H17N3O4S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:395.43
  • Ciprofibrate

    CAS:
    <p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>
    Formula:C13H14Cl2O3
    Purity:99.63% - >99.99%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:289.15
  • Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purity:97.02% - 99.94%
    Color and Shape:White Powder
    Molecular weight:434.35
  • MK-886

    CAS:
    <p>MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).</p>
    Formula:C27H34ClNO2S
    Purity:99.23% - 99.84%
    Color and Shape:Solid
    Molecular weight:472.08
  • LJ570

    CAS:
    <p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>
    Formula:C27H22O3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:394.46
  • Choline Fenofibrate

    CAS:
    <p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>
    Formula:C22H28ClNO5
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:421.91
  • Rosiglitazone

    CAS:
    <p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>
    Formula:C18H19N3O3S
    Purity:98.61% - 99.87%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:357.43
  • NPC 15199

    CAS:
    <p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>
    Formula:C21H23NO4
    Purity:99.93% - 99.94%
    Color and Shape:White Crystalline Powder
    Molecular weight:353.41
  • Seladelpar

    CAS:
    <p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>
    Formula:C21H23F3O5S
    Purity:99.18% - 99.41%
    Color and Shape:Solid
    Molecular weight:444.46
  • Norathyriol

    CAS:
    <p>Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.</p>
    Formula:C13H8O6
    Purity:99.35% - 99.55%
    Color and Shape:Solid
    Molecular weight:260.2
  • Pirinixic Acid

    CAS:
    <p>Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.</p>
    Formula:C14H14ClN3O2S
    Purity:98.27% - 99.92%
    Color and Shape:Solid
    Molecular weight:323.8
  • Bilobetin

    CAS:
    <p>Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.</p>
    Formula:C31H20O10
    Purity:97.74% - 99.69%
    Color and Shape:Solid
    Molecular weight:552.48
  • GW 501516

    CAS:
    <p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>
    Formula:C21H18F3NO3S2
    Purity:98.91% - 99.64%
    Color and Shape:White Solid
    Molecular weight:453.50
  • OPHIOPOGONIN D

    CAS:
    <p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>
    Formula:C44H70O16
    Purity:99.46% - ≥95%
    Color and Shape:Solid
    Molecular weight:855.02
  • BMS-687453

    CAS:
    <p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>
    Formula:C22H21ClN2O6
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:444.86
  • Licarin B

    CAS:
    <p>1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.</p>
    Formula:C20H20O4
    Purity:99.82% - ≥95%
    Color and Shape:Solid
    Molecular weight:324.37
  • Eupatilin

    CAS:
    <p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>
    Formula:C18H16O7
    Purity:98.53% - 99%
    Color and Shape:Solid
    Molecular weight:344.32
  • GW9662

    CAS:
    <p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>
    Formula:C13H9ClN2O3
    Purity:98% - 99.95%
    Color and Shape:Off-White Solid
    Molecular weight:276.68
  • SR1664

    CAS:
    <p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>
    Formula:C33H29N3O5
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:547.6
  • FH535

    CAS:
    <p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>
    Formula:C13H10Cl2N2O4S
    Purity:98.25% - 99.5%
    Color and Shape:Solid
    Molecular weight:361.2
  • Icariin

    CAS:
    <p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>
    Formula:C33H40O15
    Purity:97.82% - 98.3%
    Color and Shape:Solid
    Molecular weight:676.66
  • Glabrone

    CAS:
    <p>Glabrone shows antiviral activity against influenza virus.</p>
    Formula:C20H16O5
    Purity:99.08% - 99.55%
    Color and Shape:Solid
    Molecular weight:336.34
  • GW6471

    CAS:
    <p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>
    Formula:C35H36F3N3O4
    Purity:98.23% - 99.55%
    Color and Shape:Solid
    Molecular weight:619.67
  • Palmitelaidic Acid

    CAS:
    <p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>
    Formula:C16H30O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:254.41
  • NSC-87877 disodium

    CAS:
    <p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>
    Formula:C19H13N3O7S2·2Na
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:503.42
  • SR 16832

    CAS:
    <p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>
    Formula:C17H12ClN3O4
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:357.75
  • GW0742

    CAS:
    <p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>
    Formula:C21H17F4NO3S2
    Purity:99.75% - 99.85%
    Color and Shape:Solid
    Molecular weight:471.49
  • CDDO-Im

    CAS:
    <p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>
    Formula:C34H43N3O3
    Purity:98.3% - 99.61%
    Color and Shape:Solid
    Molecular weight:541.72
  • SC-236

    CAS:
    <p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>
    Formula:C16H11ClF3N3O2S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:401.79
  • Raspberry ketone

    CAS:
    <p>1.</p>
    Formula:C10H12O2
    Purity:99.84% - 99.89%
    Color and Shape:White Solid Crystalline
    Molecular weight:164.2
  • Fisetin

    CAS:
    <p>Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.</p>
    Formula:C15H10O6
    Purity:94.14% - 99.05%
    Color and Shape:Yellow To Brown Crystalline Powder
    Molecular weight:286.24
  • Ginsenoside Rh1

    CAS:
    <p>Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.</p>
    Formula:C36H62O9
    Purity:99% - 99.77%
    Color and Shape:Solid
    Molecular weight:638.87
  • Alpinetin

    CAS:
    <p>Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth &amp; activates caspases.</p>
    Formula:C16H14O4
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:270.28
  • Glabridin

    CAS:
    <p>Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.</p>
    Formula:C20H20O4
    Purity:99.78% - 99.99%
    Color and Shape:Light Yellow Powder Insoluble In Water
    Molecular weight:324.37
  • Convallatoxin

    CAS:
    <p>Convallatoxin is a natural product.</p>
    Formula:C29H42O10
    Purity:99.27% - 99.53%
    Color and Shape:Prisms From Methanol + Ether Solid
    Molecular weight:550.64
  • Methyl oleanonate

    CAS:
    <p>3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.</p>
    Formula:C31H48O3
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:468.71
  • Astaxanthin

    CAS:
    <p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>
    Formula:C40H52O4
    Purity:95.1% - 99.79%
    Color and Shape:Needles From Acetone/Light Petroleum Solid
    Molecular weight:596.84
  • Agrimol B

    CAS:
    <p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>
    Formula:C37H46O12
    Purity:99.06% - ≥95%
    Color and Shape:Solid
    Molecular weight:682.75
  • (E/Z)-Elafibranor

    CAS:
    <p>GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.</p>
    Formula:C22H24O4S
    Purity:98.36%
    Color and Shape:Solid
    Molecular weight:384.49
  • Adelmidrol

    CAS:
    <p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>
    Formula:C13H26N2O4
    Purity:99.35% - 99.73%
    Color and Shape:Solid
    Molecular weight:274.36
  • GW1929

    CAS:
    <p>GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).</p>
    Formula:C30H29N3O4
    Purity:98.1% - 98.21%
    Color and Shape:Solid
    Molecular weight:495.57
  • Bocidelpar

    CAS:
    <p>Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.</p>
    Formula:C25H27F3N2O3
    Purity:97.77%
    Color and Shape:Solid
    Molecular weight:460.49
  • Troglitazone

    CAS:
    <p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>
    Formula:C24H27NO5S
    Purity:98% - 99.8%
    Color and Shape:Yellow Solid
    Molecular weight:441.54
  • Tetradecylthioacetic acid

    CAS:
    <p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>
    Formula:C16H32O2S
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:288.49