Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 124 products of "Lipoxygenase"
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Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29Diethylcarbamazine citrate
CAS:<p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>Formula:C10H21N3O·C6H8O7Purity:99.61%Color and Shape:White Crystalline Powder And Animals (Epa 1998)Molecular weight:391.42Meclofenoxate hydrochloride
CAS:<p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>Formula:C12H16ClNO3·HClPurity:97.05%Color and Shape:White Crystal PowderMolecular weight:294.17Lagunamycin
CAS:<p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>Formula:C19H21N3O4Color and Shape:SolidMolecular weight:355.3913-epi-12-oxo Phytodienoic Acid
CAS:<p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Formula:C20H36O3Color and Shape:SolidMolecular weight:324.5055-Lipoxygenase-IN-3
CAS:<p>Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>Formula:C19H16ClN5OColor and Shape:SolidMolecular weight:365.82Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Color and Shape:SolidMolecular weight:284.26715-LOX-1 inhibitor 1
CAS:<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Formula:C22H21ClN2O4Color and Shape:SolidMolecular weight:412.87DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Formula:C8H10N4SPurity:98%Color and Shape:SoildMolecular weight:194.26(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424CMI977
CAS:<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Formula:C16H19FN2O4Purity:98%Color and Shape:SolidMolecular weight:322.33E 6080 HCl
CAS:<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:SoildMolecular weight:413.945-LOX-IN-5
<p>Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research</p>Formula:C19H18BrN3O2SPurity:98%Color and Shape:SolidMolecular weight:432.33ZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.44CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Formula:C13H14ClN3Purity:99.36%Color and Shape:SoildMolecular weight:247.72h15-LOX-2 inhibitor 2
<p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.422-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formula:C11H10OPurity:98.33%Color and Shape:SolidMolecular weight:158.21-Naphthyl 3,5-dinitrobenzoate
CAS:<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Formula:C17H10N2O6Purity:99.79%Color and Shape:SolidMolecular weight:338.27ThioLox
CAS:<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Formula:C15H18N2OSPurity:99.98%Color and Shape:SoildMolecular weight:274.385-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.42mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formula:C20H22N4O6SMolecular weight:446.12601Caffeoylcalleryanin
CAS:<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Formula:C22H24O11Color and Shape:SolidMolecular weight:464.4Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Formula:C13H16FeN2O2Color and Shape:SolidMolecular weight:288.12Myxochelin A
CAS:<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Formula:C20H24N2O7Color and Shape:SolidMolecular weight:404.419CJ-13,610 hydrochloride
CAS:<p>CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological</p>Formula:C22H24ClN3O2SPurity:98.5%Color and Shape:SoildMolecular weight:429.96LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Formula:C21H25FN4O2SColor and Shape:SolidMolecular weight:416.51Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Formula:C16H14N2SPurity:99.34%Color and Shape:SolidMolecular weight:266.36Lipoxygenase
CAS:<p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>Color and Shape:SolidAureusidin
CAS:<p>Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.</p>Formula:C15H10O6Purity:98.17% - 99.18%Color and Shape:SolidMolecular weight:286.24Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C19H15NO4Color and Shape:SolidMolecular weight:321.33Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formula:C11H11N2NaO2SColor and Shape:SolidMolecular weight:258.274',5-Dihydroxyflavone
CAS:<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Formula:C15H10O4Purity:99.81%Color and Shape:SolidMolecular weight:254.24Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Formula:C12H16O4S2Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:288.384-MMPB
CAS:<p>15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.</p>Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:SolidMolecular weight:246.3LOX-IN-3 dihydrochloride
CAS:<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Formula:C13H15Cl2FN2O2SPurity:99.96%Color and Shape:SolidMolecular weight:353.24Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formula:C18H18O4Purity:99.88% - 99.91%Color and Shape:SolidMolecular weight:298.33Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formula:C9H10N2OPurity:97.24%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19Chebulagic acid
CAS:<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Formula:C41H30O27Purity:97.82% - 99.8%Color and Shape:SolidMolecular weight:954.66Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.26PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Formula:C19H26O3Purity:99.39%Color and Shape:SolidMolecular weight:302.41Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Formula:C20H16O5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:336.34SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Formula:C16H11N3O2Purity:99.55%Color and Shape:Dark Red SolidMolecular weight:277.283-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:<p>3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).</p>Formula:C32H50O5Purity:98.24%Color and Shape:SolidMolecular weight:514.74Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36β-Aminopropionitrile hydrochloride
CAS:<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Formula:C3H7ClN2Purity:99.32%Color and Shape:SolidMolecular weight:106.55β-Boswellic acid
CAS:<p>β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic</p>Formula:C30H48O3Purity:99.2% - 99.91%Color and Shape:Off-White SolidMolecular weight:456.7ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Formula:C12H13NO3Purity:98.9%Color and Shape:Off-White To Light Tan Crystalline PowderMolecular weight:219.24BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Formula:C15H14ClN3OPurity:99.34%Color and Shape:SolidMolecular weight:287.74Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:SolidMolecular weight:314.29Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Formula:C9H8O4Purity:98.89% - 99.3%Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Molecular weight:180.162,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Formula:C20H20ClN3O3Purity:99.94%Color and Shape:SolidMolecular weight:385.845-O-Demethylnobiletin
CAS:<p>5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.</p>Formula:C20H20O8Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:388.37FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Formula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31ML351
CAS:<p>ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).</p>Formula:C15H11N3OPurity:97.67%Color and Shape:SolidMolecular weight:249.27Linoleyl alcohol
CAS:<p>Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].</p>Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Formula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Formula:C21H19N3O4S2Purity:98.02% - 98.2%Color and Shape:SolidMolecular weight:441.5211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25CAY10698
CAS:<p>CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).</p>Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.645-LOX inhibitor
CAS:<p>5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.</p>Formula:C22H27N5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.48a-Boswellic Acid
CAS:Controlled Product<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Formula:C30H48O3Color and Shape:NeatMolecular weight:456.70Golocdacimab
CAS:<p>Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.</p>Purity:95%Color and Shape:Liquid4-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24tHGA
CAS:<p>tHGA is a potent inhibitor of lipoxygenase.</p>Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4L 652343
CAS:<p>L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.</p>Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.482-TEDC
CAS:<p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>Formula:C16H13NO4SPurity:99.75%Color and Shape:SolidMolecular weight:315.34Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37RWJ 63556
CAS:<p>RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.</p>Formula:C11H10FNO3S2Purity:99.92%Color and Shape:SolidMolecular weight:287.33AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:<p>PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.</p>Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5Enazadrem
CAS:<p>Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.</p>Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41Fluindione
CAS:<p>Fluindione is a hematologic drug.</p>Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23LY 269415
CAS:<p>LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.</p>Formula:C19H28N2O2SColor and Shape:SolidMolecular weight:348.5YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96Lipoxygenin
CAS:<p>Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.</p>Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44LP117
CAS:<p>LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).</p>Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95ICI 211965
CAS:<p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51Fenleuton
CAS:<p>Fenleuton is a 5-lipoxygenase inhibitor.</p>Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31LY 221068
CAS:<p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.53L 656224
CAS:<p>L 656224 is a 5-LO inhibitor.</p>Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83Texasin
CAS:<p>Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.</p>Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26Cgp 8065
CAS:<p>Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.</p>Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44EP6
CAS:<p>EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.</p>Formula:C24H30N4OPurity:98%Color and Shape:SolidMolecular weight:390.52HZ52
CAS:<p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>Formula:C24H26ClN3O2SColor and Shape:SolidMolecular weight:456RG 6866
CAS:<p>RG 6866 is a inhibitor of 5-lipoxygenase.</p>Formula:C16H17NO3Purity:98%Color and Shape:SolidMolecular weight:271.31L-651392
CAS:<p>L-651392 is an inhibitor of leukotriene.</p>Formula:C14H10BrNO3SColor and Shape:SolidMolecular weight:352.2MLS000536924
CAS:<p>MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.</p>Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38A-69412
CAS:<p>A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.</p>Formula:C7H10N2O3Purity:99.54%Color and Shape:SolidMolecular weight:170.17Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Formula:C18H28O2Purity:99.95%Color and Shape:SolidMolecular weight:276.41Butibufen
CAS:<p>Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.</p>Formula:C14H20O2Purity:98.11% - 98.91%Color and Shape:SolidMolecular weight:220.31Lonapalene
CAS:<p>Lonapalene is a topically effective inhibitor of 5-lipoxygenase.</p>Formula:C16H15ClO6Purity:98.67% - 99.33%Color and Shape:SolidMolecular weight:338.74S-2474
CAS:<p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>Formula:C20H31NO3SPurity:99.03%Color and Shape:SolidMolecular weight:365.535-LOX-IN-1
CAS:<p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>Formula:C20H18N2O2SPurity:97.45%Color and Shape:SolidMolecular weight:350.43h15-LOX-2 inhibitor 1
CAS:<p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>Formula:C17H13F3N2SPurity:98%Color and Shape:SolidMolecular weight:334.365,6-dehydro Arachidonic Acid
CAS:<p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>Formula:C20H30O2Color and Shape:SolidMolecular weight:302.45A 78773
CAS:<p>A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.</p>Formula:C15H13FN2O4Color and Shape:SolidMolecular weight:304.27L 670630
CAS:<p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>Formula:C25H26O3Purity:98%Color and Shape:SolidMolecular weight:374.47AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43A 79175
CAS:<p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>Formula:C15H13FN2O4Purity:98%Color and Shape:SolidMolecular weight:304.27CMI-392
CAS:<p>CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).</p>Formula:C31H37ClN2O8SPurity:98%Color and Shape:SolidMolecular weight:633.15MLS000545091
CAS:<p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>Formula:C14H15ClN2OPurity:99.84%Color and Shape:SolidMolecular weight:262.73Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.725-Lipoxygenase-In-1
CAS:<p>5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.</p>Formula:C23H28N4O2SColor and Shape:SolidMolecular weight:424.5617(S)-HpDHA
CAS:<p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Formula:C18H17NO4S3Purity:97.299% - 99.49%Color and Shape:SolidMolecular weight:407.53PXS-6302 hydrochloride
CAS:<p>PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3</p>Formula:C10H11ClF3NO2SPurity:99.89%Color and Shape:SoildMolecular weight:301.71Setileuton
CAS:<p>Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.</p>Formula:C22H17F4N3O4Purity:98.85% - 99.35%Color and Shape:SolidMolecular weight:463.38h15-LOX-2 inhibitor 3
CAS:<p>Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.</p>Formula:C22H13N5O3Color and Shape:SolidMolecular weight:395.37AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5ALOX15-IN-1
<p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>Formula:C24H31N3O5SColor and Shape:SolidMolecular weight:473.595-LOX/MAOs-IN-1
CAS:<p>Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.</p>Formula:C18H18N2O2Color and Shape:SolidMolecular weight:294.35L 691816
CAS:<p>L 691816 is an effective inhibitor of the 5-LO reaction.</p>Formula:C36H35ClN6OSPurity:98%Color and Shape:SolidMolecular weight:635.22ALOX15-IN-2
CAS:<p>ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.</p>Formula:C23H29N3O4SPurity:98.10%Color and Shape:SolidMolecular weight:443.56CJ-13,610
CAS:<p>CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.</p>Formula:C22H23N3O2SPurity:99.64%Color and Shape:SolidMolecular weight:393.5
