Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(939 products)
- ACK(1 products)
- AChR(575 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,945 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(561 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(297 products)
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Found 5398 products of "Neuroscience"
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BChE-IN-35
<p>BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).</p>Formula:C35H39N5O2Color and Shape:SolidMolecular weight:561.72(S)-Vamicamide
CAS:<p>(S)-Vamicamide is an anti-anticholinergic compound.</p>Formula:C18H23N3OPurity:99.48% - 99.65%Color and Shape:SoildMolecular weight:297.39Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour SolidCalcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidMAO-B-IN-36
<p>MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.</p>Formula:C20H14O3Color and Shape:SolidMolecular weight:302.32CNS-Penetrant Compound Library
<p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour Solid8-hydroxy Amoxapine
CAS:<p>8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2</p>Formula:C17H16ClN3O2Color and Shape:SolidMolecular weight:329.78M4 mAChR agonist-1
CAS:<p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).</p>Formula:C14H18N4OSPurity:99.14%Color and Shape:SolidMolecular weight:290.38Neural Regeneration Compound Library
<p>A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidHamaline
CAS:<p>Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.</p>Formula:C20H19ClN2OPurity:99.88%Color and Shape:SoildMolecular weight:338.83AChE-IN-43
<p>AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].</p>Color and Shape:Odour Solidβ-Amyloid (1-15)
CAS:<p>β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.</p>Formula:C78H107N25O27Purity:99.88%Color and Shape:SolidMolecular weight:1826.84Minesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Formula:C21H31ClN4O5Purity:99.85% - 99.88%Color and Shape:SolidMolecular weight:454.95LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Formula:C20H22N2Purity:97.91% - 98.79%Color and Shape:SolidMolecular weight:290.4Apoptosis Compound Library
<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>Color and Shape:Odour Solid(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Formula:C15H23NO2SPurity:98.19%Color and Shape:SoildMolecular weight:281.41Isonaringin
CAS:<p>Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.</p>Formula:C27H32O14Color and Shape:SolidMolecular weight:580.531H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formula:C10H12N2O2SPurity:99.96%Color and Shape:SoildMolecular weight:224.28MK-0969
CAS:<p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Formula:C24H30F2N4O2Color and Shape:SolidMolecular weight:444.52Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Purity:95% - 97.10%Color and Shape:LiquidMolecular weight:145.93 kDaPemedolac
CAS:<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Formula:C22H23NO3Purity:>99.99%Color and Shape:SolidMolecular weight:349.42AChE/BChE-IN-26
<p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>Color and Shape:Odour SolidPyridostigmine bromide
CAS:<p>Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.</p>Formula:C9H13BrN2O2Purity:99.00% - 99.98%Color and Shape:White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidMolecular weight:261.123-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formula:C3H10NO3PPurity:99.84%Color and Shape:Light Yellow LiquidMolecular weight:139.09Neuronal Signaling Compound Library
<p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Color and Shape:Odour SolidAntidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.37ACG548B
CAS:<p>ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.</p>Formula:C38H34Br2Cl2N4Color and Shape:SolidMolecular weight:777.43Small Cardioactive Peptide B (SCPB)
CAS:<p>SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).</p>Formula:C52H80N14O11S2Purity:98%Color and Shape:SolidMolecular weight:1141.41ANQ-9040
CAS:<p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>Formula:C36H58N2O5SColor and Shape:SolidMolecular weight:630.92SQ-3
<p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>Formula:C21H21FN2OColor and Shape:SolidMolecular weight:336.4Methyl ganoderate A acetonide
CAS:<p>Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.</p>Formula:C34H50O7Color and Shape:SolidMolecular weight:570.76C175-0062
CAS:<p>C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].</p>Formula:C21H18N2O5Color and Shape:SolidMolecular weight:378.38Aceclidine (hydrochloride)
CAS:<p>agonist of muscarinic receptors</p>Formula:C9H16ClNO2Purity:98%Color and Shape:SolidMolecular weight:205.68Camlipixant
CAS:<p>Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.</p>Formula:C23H24F2N4O4Purity:99.37%Color and Shape:SoildMolecular weight:458.46Sodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidCoumarinic acid
CAS:<p>Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].</p>Formula:C9H8O3Color and Shape:SolidMolecular weight:164.168-Aminoadenine
CAS:<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Color and Shape:LiquidnAChR modulator-2
CAS:<p>nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66LtIA-F
<p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>Formula:C86H121N25O22S4Color and Shape:SolidMolecular weight:1985.31LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Formula:C23H32N2O3Color and Shape:SolidMolecular weight:384.51AMI-193
CAS:<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Formula:C22H26FN3O2Purity:99.65%Color and Shape:SolidMolecular weight:383.46Dapoxetine
CAS:<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>Formula:C21H23NOPurity:99.73%Color and Shape:White To Off-White Crystalline PowderMolecular weight:305.42β-Amyloid (1-9)
CAS:<p>This is an N-terminal fragment of beta amyloid.</p>Formula:C42H60N14O17Purity:98%Color and Shape:SolidMolecular weight:1033.01Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formula:C10H13ClN2Purity:99.89%Color and Shape:SolidMolecular weight:196.68Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Color and Shape:SolidMolecular weight:3116.54Encecalinol
CAS:<p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>Formula:C14H18O3Color and Shape:SolidMolecular weight:234.29Anagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Formula:C15H21ClN2OColor and Shape:SolidMolecular weight:280.79Methylatropine (nitrate)
CAS:<p>Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>Formula:C18H26N2O6Color and Shape:SolidMolecular weight:366.414Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:<p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>Formula:C22H27Cl3F3N3SColor and Shape:SolidMolecular weight:528.89Chrysophanol-1-O-β-gentiobioside
CAS:<p>Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme</p>Formula:C27H30O14Color and Shape:SolidMolecular weight:578.52AChE/BChE-IN-14
<p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>Formula:C19H23NO3Color and Shape:SolidMolecular weight:313.39Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.5Lupanine hydrochloride
CAS:<p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>Formula:C15H25ClN2OColor and Shape:SolidMolecular weight:284.83DISC-0974
<p>DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.</p>Color and Shape:LiquidMolecular weight:145.5kDaGABA-A Receptor Ligand-1
<p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>Formula:C20H20FN3OColor and Shape:SolidMolecular weight:337.391Fasciculic acid B
CAS:<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Formula:C36H60O9Purity:98%Color and Shape:SolidMolecular weight:636.86Cabergoline
CAS:<p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>Formula:C26H37N5O2Purity:97.69% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:451.6HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formula:C18H22O2Color and Shape:SolidMolecular weight:270.37epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Formula:C28H30N2O7Color and Shape:SolidMolecular weight:506.2053CHF-5022
CAS:<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formula:C17H12F4O2Color and Shape:SolidMolecular weight:324.27CGP 35348
CAS:<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Formula:C8H20NO4PPurity:≥98%Color and Shape:SolidMolecular weight:225.22SSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Formula:C17H24FN5O2Color and Shape:SolidMolecular weight:349.414-P-PDOT
CAS:<p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>Formula:C19H21NOPurity:99.91%Color and Shape:SolidMolecular weight:279.38Epiboxidine
CAS:<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23Emraclidine
CAS:<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Formula:C20H21F3N4OPurity:99.96%Color and Shape:SolidMolecular weight:390.4Nardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33Withasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formula:C28H36O4Color and Shape:SolidMolecular weight:436.58Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Formula:C43H58N2O17Purity:98.03% - 98.91%Color and Shape:SolidMolecular weight:874.92Blestrin D
CAS:<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Formula:C30H24O6Color and Shape:SolidMolecular weight:480.51SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04JH-XII-03-02
CAS:<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Formula:C43H51N9O10Purity:98%Color and Shape:SolidMolecular weight:853.92Calmodulin Binding Peptide 1
CAS:<p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>Formula:C231H373N69O70S2Purity:98%Color and Shape:SolidMolecular weight:5301.1TIP 39, Tuberoinfundibular Neuropeptide
CAS:<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Formula:C202H325N61O54SPurity:98%Color and Shape:SolidMolecular weight:4504.2AChE-IN-40
<p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>Formula:C23H27NO4Color and Shape:SolidMolecular weight:381.46TC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43AChE-IN-45
<p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>Color and Shape:Odour SolidBrexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formula:C25H19D8N3O3SPurity:98%Color and Shape:SolidMolecular weight:457.61TRV-7019
CAS:<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formula:C14H12INO3Color and Shape:SolidMolecular weight:369.15pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formula:C10H13Cl2NO2Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:250.12YS-370
CAS:<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Formula:C37H35BrN4O3Purity:98.055%Color and Shape:SolidMolecular weight:663.6VU6028418
CAS:<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Color and Shape:SolidGABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Formula:C15H17BrO4SColor and Shape:SolidMolecular weight:373.26GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formula:C16H17ClN4O2Color and Shape:SolidMolecular weight:332.791,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25(R)-(+)-Anatabine
CAS:<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Formula:C10H12N2Purity:98%Color and Shape:SolidMolecular weight:160.22(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.47[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Formula:C120H206N44O35SPurity:98%Color and Shape:SolidMolecular weight:2857.285-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formula:C25H30N4O2SColor and Shape:SolidMolecular weight:450.6LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.581-Ethyl-1H-indole
CAS:<p>1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.</p>Formula:C10H11NPurity:98.80%Color and Shape:SolidMolecular weight:145.2BACE1-IN-15
<p>BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.</p>Color and Shape:Odour SolidJF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:SolidSyk Inhibitor II hydrochloride
CAS:<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formula:C14H16ClF3N6OPurity:99.05%Color and Shape:SolidMolecular weight:376.77Fasciculic acid C
CAS:<p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formula:C38H63NO11Purity:98%Color and Shape:SolidMolecular weight:709.91Neuroprotective Compound Library
<p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>Color and Shape:Odour SolidRiluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formula:CC7H5F3OS15N2Color and Shape:SolidMolecular weight:237.18
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