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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1093 products of "Proteases/Proteasome"

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  • 6-Acetylnimbandiol

    CAS:
    6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.
    Formula:C28H34O8
    Color and Shape:Solid
    Molecular weight:498.56

    Ref: TM-T75506

    5mg
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    50mg
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  • TP0597850

    CAS:
    TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].
    Formula:C41H57N9O13S
    Color and Shape:Solid
    Molecular weight:916.01

    Ref: TM-T74714

    5mg
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    50mg
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  • α 1(I) Collagen (614-639), human

    CAS:
    This is a peptide inhibitor of collagen fibrillar matrix assembly.
    Formula:C134H189N37O39
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2942.16

    Ref: TM-TP1643

    100mg
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    500mg
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  • Cyanopeptolin 954

    CAS:
    Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.
    Formula:C46H63ClN8O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:955.5

    Ref: TM-T25280

    5mg
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  • BMS-767778

    CAS:
    BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29

    Ref: TM-T26857

    25mg
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  • Benzamidine

    CAS:
    Benzamidine is a reversible competitive inhibitor of trypsin with a Ki of 19 μM. It also exhibits inhibitory activity on an enzyme in homogenized porcine sperm acrosome, with a Ki of 4 μM.
    Formula:C7H8N2
    Color and Shape:Solid
    Molecular weight:120.15

    Ref: TM-T203133

    10mg
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    50mg
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  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200602

    10mg
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    50mg
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  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
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    500mg
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  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
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    50mg
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  • Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

    CAS:
    Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).
    Formula:C49H68N14O12S
    Color and Shape:Solid
    Molecular weight:1077.22

    Ref: TM-T36360

    1mg
    404.00€
  • GSK2336805

    CAS:
    GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.
    Formula:C42H52N8O8
    Color and Shape:Solid
    Molecular weight:796.91

    Ref: TM-T27461

    25mg
    2,300.00€
    50mg
    3,022.00€
    100mg
    4,085.00€
  • RJS308


    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
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  • Stevia Powder


    Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.
    Color and Shape:Odour Solid

    Ref: TM-TN8189

    10mg
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    50mg
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  • Zetomipzomib maleate

    CAS:
    Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.
    Formula:C34H46N4O12
    Color and Shape:Solid
    Molecular weight:702.758

    Ref: TM-T39653

    5mg
    1,415.00€
  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
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    50mg
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  • Histargin

    CAS:
    Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
    Formula:C14H25N7O4
    Color and Shape:Solid
    Molecular weight:355.39

    Ref: TM-T25504

    25mg
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  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    105.00€
    10mg
    157.00€
    50mg
    575.00€
  • Tyrosinase-IN-34


    Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7

    Ref: TM-T89968

    10mg
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    50mg
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  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53

    Ref: TM-T75492

    5mg
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    50mg
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  • MeOSuc-AAPA-CMK


    MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].
    Formula:C20H31ClN4O8
    Color and Shape:Solid
    Molecular weight:490.94

    Ref: TM-T80553

    5mg
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    50mg
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