
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(110 products)
- DPP-4(20 products)
- Glutaminase(44 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(95 products)
- Serine Protease(56 products)
- p97(15 products)
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Found 1093 products of "Proteases/Proteasome"
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6-Acetylnimbandiol
CAS:6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.Formula:C28H34O8Color and Shape:SolidMolecular weight:498.56TP0597850
CAS:TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].Formula:C41H57N9O13SColor and Shape:SolidMolecular weight:916.01α 1(I) Collagen (614-639), human
CAS:This is a peptide inhibitor of collagen fibrillar matrix assembly.Formula:C134H189N37O39Purity:98%Color and Shape:SolidMolecular weight:2942.16Cyanopeptolin 954
CAS:Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.Formula:C46H63ClN8O12Purity:98%Color and Shape:SolidMolecular weight:955.5BMS-767778
CAS:BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C19H20Cl2N4O2Color and Shape:SolidMolecular weight:407.29Benzamidine
CAS:Benzamidine is a reversible competitive inhibitor of trypsin with a Ki of 19 μM. It also exhibits inhibitory activity on an enzyme in homogenized porcine sperm acrosome, with a Ki of 4 μM.Formula:C7H8N2Color and Shape:SolidMolecular weight:120.15Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Color and Shape:Odour SolidN-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formula:C33H36N6O6Purity:98%Color and Shape:White To Off-White PowderMolecular weight:612.68Phaeosphaone D
CAS:Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).Formula:C20H27N3O3S2Color and Shape:SolidMolecular weight:421.58Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
CAS:Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).Formula:C49H68N14O12SColor and Shape:SolidMolecular weight:1077.22GSK2336805
CAS:GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.Formula:C42H52N8O8Color and Shape:SolidMolecular weight:796.91RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Formula:C63H75N13O11SColor and Shape:SolidMolecular weight:1222.42Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Color and Shape:Odour SolidZetomipzomib maleate
CAS:Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.Formula:C34H46N4O12Color and Shape:SolidMolecular weight:702.758Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofColor and Shape:Odour SolidHistargin
CAS:Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formula:C14H25N7O4Color and Shape:SolidMolecular weight:355.39Talabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Formula:C9H19BN2O3Color and Shape:SolidMolecular weight:214.07Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColor and Shape:SolidMolecular weight:429.7Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53MeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formula:C20H31ClN4O8Color and Shape:SolidMolecular weight:490.94

