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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1063 products of "Proteases/Proteasome"

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  • Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

    CAS:
    Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).
    Formula:C49H68N14O12S
    Color and Shape:Solid
    Molecular weight:1077.22

    Ref: TM-T36360

    1mg
    384.00€
  • AR-H067637

    CAS:
    AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.
    Formula:C21H21ClF2N4O4
    Color and Shape:Solid
    Molecular weight:466.87

    Ref: TM-T26657

    25mg
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    50mg
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    100mg
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  • Talabostat isomer mesylate


    Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).
    Formula:C10H23BN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.18

    Ref: TM-T13069

    25mg
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    50mg
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    100mg
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  • Tyrosinase/elastase-IN-1


    Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase
    Formula:C33H52O5
    Color and Shape:Solid
    Molecular weight:528.76

    Ref: TM-T74243

    5mg
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    50mg
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  • Rivulariapeptolides 1121


    Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
    Formula:C56H83N9O15
    Color and Shape:Solid
    Molecular weight:1122.31

    Ref: TM-T75650

    5mg
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    50mg
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  • Leptosin D

    CAS:
    Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)
    Formula:C25H24N4O3S2
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T75472

    5mg
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    50mg
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  • Apovincamine

    CAS:
    Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.
    Formula:C21H24N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.44

    Ref: TM-T21047

    25mg
    1,444.00€
  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64

    Ref: TM-T14180

    1mg
    187.00€
    5mg
    472.00€
    10mg
    687.00€
    25mg
    1,074.00€
    50mg
    1,444.00€
  • Sofosbuvir impurity N

    CAS:
    Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C20H25FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.404

    Ref: TM-T12969

    25mg
    2,808.00€
    50mg
    3,492.00€
    100mg
    4,500.00€
  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • PSI-353661

    CAS:
    PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.
    Formula:C24H32FN6O8P
    Color and Shape:Solid
    Molecular weight:582.52

    Ref: TM-T74301

    5mg
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    50mg
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  • LMP7/LMP2-IN-1

    CAS:
    LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.
    Formula:C16H27BN4O3
    Color and Shape:Soild
    Molecular weight:334.22

    Ref: TM-T88971

    10mg
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    50mg
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  • VD2173

    CAS:
    <p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
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    50mg
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  • Suc-AAP-Abu-pNA

    CAS:
    Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,
    Formula:C25H34N6O9
    Color and Shape:Solid
    Molecular weight:562.57

    Ref: TM-T36351

    1mg
    139.00€
  • Tyrosinase-IN-32


    Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.
    Formula:C15H19NO3
    Color and Shape:Solid
    Molecular weight:261.32

    Ref: TM-TN8160

    10mg
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    50mg
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  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • Acetyl-Calpastatin(184-210)(human) TFA


    Acetyl-Calpastatin(184-210)(human) TFA inhibits μ-calpain (Ki 0.2 nM) and cathepsin L (Ki 6 μM) selectively and reversibly.
    Formula:C144H231F3N36O46S
    Color and Shape:Solid
    Molecular weight:3291.65

    Ref: TM-T75794

    5mg
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    50mg
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  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,626.00€
  • 5-epi-Arvestonate A

    CAS:
    <p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>
    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
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    50mg
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  • Ellipyrone B


    Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57

    Ref: TM-T75493

    5mg
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    50mg
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