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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1032 products of "Proteases/Proteasome"

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  • N-CBZ-Phe-Arg-AMC TFA


    N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:726.7

    Ref: TM-T76010

    1mg
    54.00€
    5mg
    115.00€
    10mg
    169.00€
    25mg
    331.00€
    50mg
    526.00€
  • L 659286

    CAS:
    L 659286 is one kind of cephalosporin derivative.
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51

    Ref: TM-T32460

    25mg
    1,369.00€
  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
    To inquire
    500mg
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  • Tyrosinase-IN-34


    Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7

    Ref: TM-T89968

    10mg
    To inquire
    50mg
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  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53

    Ref: TM-T75492

    5mg
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    50mg
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  • Leptosin D

    CAS:
    Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)
    Formula:C25H24N4O3S2
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T75472

    5mg
    To inquire
    50mg
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  • Activated Protein C (390-404), human

    CAS:
    Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.
    Formula:C91H130N22O23
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1900.14

    Ref: TM-TP1628

    100mg
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    500mg
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  • Histatin 5

    CAS:
    Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29

    Ref: TM-TP1741

    1mg
    172.00€
    5mg
    593.00€
    10mg
    940.00€
  • Fibrinogen-Binding Peptide

    CAS:
    Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.
    Formula:C25H39N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.62

    Ref: TM-TP1736

    100mg
    To inquire
    500mg
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  • GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002

    Ref: TM-T38858

    5mg
    922.00€
  • Sofigatran

    CAS:
    Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.
    Formula:C24H44N4O4S
    Color and Shape:Solid
    Molecular weight:484.7

    Ref: TM-T39310

    5mg
    873.00€
  • Chetoseminudin B

    CAS:
    Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].
    Formula:C17H21N3O3S2
    Color and Shape:Solid
    Molecular weight:379.5

    Ref: TM-T75471

    5mg
    To inquire
    50mg
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  • STK33-IN-1

    CAS:
    STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527

    Ref: TM-T38835

    5mg
    922.00€
  • CRA-2059 hydrochloride


    CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
    Color and Shape:Solid

    Ref: TM-T38051

    5mg
    315.00€
    10mg
    492.00€
    25mg
    960.00€
  • Plasma kallikrein-IN-1

    CAS:
    Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
    Formula:C23H25F2N7O
    Color and Shape:Solid
    Molecular weight:453.498

    Ref: TM-T40312

    5mg
    873.00€
  • Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)


    Fluorogenic substrate for cathepsins D & E; cleaves at Phe-Phe bond; not for B, H, L. Useful for assays and studies.
    Color and Shape:Odour Solid

    Ref: TM-T38254

    5mg
    208.00€
    10mg
    336.00€
    25mg
    665.00€
  • JC-10

    CAS:
    JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34

    Ref: TM-TD0056

    1mg
    118.00€
  • Tilpisertib fosmecarbil TFA

    CAS:
    Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.
    Formula:C37H37ClF3N8O9P
    Color and Shape:Solid
    Molecular weight:861.16

    Ref: TM-T88817

    10mg
    To inquire
    50mg
    To inquire
  • Atecegatran TFA

    CAS:
    Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease.
    Formula:C23H22ClF5N4O6
    Purity:97.47% - 99.77%
    Color and Shape:Solid
    Molecular weight:580.89

    Ref: TM-T30191L

    1mg
    185.00€
    5mg
    459.00€
    50mg
    1,415.00€
    100mg
    1,872.00€
  • Rivulariapeptolides 1185


    Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.
    Formula:C61H87N9O15
    Color and Shape:Solid
    Molecular weight:1186.39

    Ref: TM-T75649

    5mg
    To inquire
    50mg
    To inquire