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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1095 products of "Proteases/Proteasome"

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  • MMP-9/MMP-13 Inhibitor I

    CAS:
    MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.
    Formula:C25H25N3O6S
    Color and Shape:Solid
    Molecular weight:495.55

    Ref: TM-T37172

    25mg
    780.00€
  • Z-FG-NHO-Bz

    CAS:
    Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].
    Formula:C26H25N3O6
    Color and Shape:Solid
    Molecular weight:475.49

    Ref: TM-T80740

    5mg
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    50mg
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  • NVP-DPP728 dihydrochloride

    CAS:
    NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27

    Ref: TM-T39481

    25mg
    1,444.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
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    50mg
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  • MeOSuc-AAPA-CMK


    MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].
    Formula:C20H31ClN4O8
    Color and Shape:Solid
    Molecular weight:490.94

    Ref: TM-T80553

    5mg
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    50mg
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  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,884.00€
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805

    Ref: TM-T19948

    50mg
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    100mg
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  • Enzyme-IN-1

    CAS:
    Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。
    Formula:C36H50N4O7
    Color and Shape:Solid
    Molecular weight:650.8

    Ref: TM-T74878

    5mg
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    50mg
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  • CRA-2059 hydrochloride


    CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
    Color and Shape:Solid

    Ref: TM-T38051

    5mg
    333.00€
    10mg
    518.00€
    25mg
    1,014.00€
  • Nitidanin


    Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415

    Ref: TM-T125599

    1mg
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    5mg
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  • Tyrosinase-IN-32


    Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.
    Formula:C15H19NO3
    Color and Shape:Solid
    Molecular weight:261.32

    Ref: TM-TN8160

    10mg
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    50mg
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  • RJS308


    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
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    50mg
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  • α 1 Antichymotrypsin, Human Plasma

    CAS:
    Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.
    Color and Shape:Solid

    Ref: TM-TP3129

    10mg
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    50mg
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  • 15,16-Dihydrotanshindiol C


    15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337

    Ref: TM-T123985

    1mg
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    5mg
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  • Dutogliptin

    CAS:
    Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C10H20BN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.10

    Ref: TM-T11128

    25mg
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    50mg
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    100mg
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  • Fotagliptin benzoate

    CAS:
    Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.
    Formula:C24H25FN6O3
    Color and Shape:Solid
    Molecular weight:464.49

    Ref: TM-T73875

    5mg
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    50mg
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  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
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    50mg
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  • L 659286

    CAS:
    L 659286 is one kind of cephalosporin derivative.
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51

    Ref: TM-T32460

    25mg
    1,444.00€
  • Acetyl-Calpastatin(184-210)(human)

    CAS:
    Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
    Formula:C142H230N36O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3177.65

    Ref: TM-TP2056

    1mg
    1,454.00€
  • Fotagliptin

    CAS:
    Fotagliptin is a dipeptidyl peptidase IV inhibitor.
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37

    Ref: TM-T27353

    5mg
    1,491.00€
    50mg
    3,022.00€
    100mg
    4,085.00€