CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 1085 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • BI 224436

    CAS:
    BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.
    Formula:C27H26N2O4
    Color and Shape:Solid
    Molecular weight:442.51
  • SD-2590 HCl

    CAS:
    SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.
    Formula:C22H26ClF3N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.96
  • Odiparcil

    CAS:
    Odiparcil is an orally active beta-d-thioxyloside analog.
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35
  • SMCypI C31


    SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).
    Formula:C27H30N4O2S
    Color and Shape:Solid
    Molecular weight:474.62
  • CE-2072

    CAS:
    CE-2072 is a synthetic host serine proteases inhibitor.
    Formula:C33H41N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.71
  • Cathepsin C-IN-4


    Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
    Formula:C21H14ClF3N4S
    Color and Shape:Solid
    Molecular weight:446.88
  • Narlaprevir

    CAS:
    Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.
    Formula:C36H61N5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:707.96
  • CM-352

    CAS:
    CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.
    Formula:C24H29N3O6S
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:487.57
  • Freselestat

    CAS:
    Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.
    Formula:C23H28N6O4
    Color and Shape:Solid
    Molecular weight:452.51
  • Tyrosinase-IN-35

    CAS:
    <p>Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.</p>
    Formula:C17H15N5OS
    Color and Shape:Solid
    Molecular weight:337.40
  • MIV-247

    CAS:
    MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.
    Formula:C17H24F3N3O4
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:391.39
  • Vaniprevir

    CAS:
    Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.
    Formula:C38H55N5O9S
    Purity:97.41%
    Color and Shape:Solid
    Molecular weight:757.94
  • JTK-109

    CAS:
    JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
    Formula:C37H33ClFN3O4
    Purity:98.48% - 99.68%
    Color and Shape:Solid
    Molecular weight:638.13
  • IDX184

    CAS:
    IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3
    Formula:C25H35N6O9PS
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:626.62
  • PD 151746

    CAS:
    <p>PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.</p>
    Formula:C11H8FNO2S
    Purity:98.63% - ≥95%
    Color and Shape:Solid
    Molecular weight:237.25
  • Sebetralstat

    CAS:
    <p>Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.</p>
    Formula:C26H26FN5O4
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:491.51
  • ALLM

    CAS:
    ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].
    Formula:C19H35N3O4S
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:401.56

    Ref: TM-T14187

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • MMP13-IN-2

    CAS:
    <p>MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.</p>
    Formula:C24H19FN6O4S
    Color and Shape:Solid
    Molecular weight:506.51

    Ref: TM-T41079

    ne
    Discontinued
    Discontinued product
  • 3-Deazaadenosine

    CAS:
    3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.
    Formula:C11H14N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:266.25

    Ref: TM-T10111L

    5mg
    Discontinued
    Discontinued product