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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1032 products of "Proteases/Proteasome"

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  • VD2173

    CAS:
    VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
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    50mg
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  • 5-epi-Arvestonate A

    CAS:

    5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.

    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
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    50mg
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  • Ichorcumab

    CAS:

    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

    Color and Shape:Liquid

    Ref: TM-T9901A-779

    1mg
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    5mg
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  • TP0628103

    CAS:
    TP0628103 (compound 18) acts as a selective MMP-7 inhibitor, exhibiting a potent IC 50 value of 0.17 nM, which is crucial in the contexts of cancer and fibrosis [1].
    Formula:C51H67ClF3N11O11S
    Color and Shape:Solid
    Molecular weight:1134.66

    Ref: TM-T87556

    10mg
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    50mg
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  • HCV-IN-7 hydrochloride

    CAS:
    HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H50Cl2N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:841.85

    Ref: TM-T11548L

    25mg
    1,369.00€
  • FiVe1

    CAS:

    FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.

    Formula:C18H16Cl2N4
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:359.25

    Ref: TM-T9657

    1mg
    313.00€
    5mg
    758.00€
    10mg
    1,035.00€
    25mg
    1,568.00€
    50mg
    2,118.00€
    100mg
    2,783.00€
  • Sofosbuvir impurity A

    CAS:
    Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45

    Ref: TM-T12956

    25mg
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    50mg
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    100mg
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  • SL44


    SL44 is an agonist of human caseinolytic protease P (HsClpP) with an EC50 of 1.30 μM. It inhibits LM3 proliferation with an IC50 of 3.1 μM and induces apoptosis in liver cancer cells by degrading respiratory chain complex subunits. In mouse models, SL44 demonstrates antitumor activity without significant toxicity (LD50=400 mg/kg) and exhibits favorable pharmacokinetic properties in rat models.
    Formula:C22H20ClFN4O
    Molecular weight:410.13097

    Ref: TM-T210251

    10mg
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    50mg
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  • LM11


    LM11 is a transglutaminase 2 (TG2) inhibitor that exhibits activity against glioblastoma cells by maintaining TG2 in a cytotoxic conformational state.

    Formula:C26H18Cl2N4O5
    Molecular weight:536.06543

    Ref: TM-T209326

    10mg
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    50mg
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  • H-Gly-Pro-Hyp-OH

    CAS:
    H-Gly-Pro-Hyp-OH is a potent and oral anti-photoaging collagen peptide and improves the hydration of human skin, elasticity and anti-wrinkle properties.
    Formula:C12H19N3O5
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:285.3

    Ref: TM-T82200

    10mg
    37.00€
    25mg
    54.00€
    50mg
    87.00€
  • TAPI1 acetate


    TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:559.65

    Ref: TM-T6009L

    1mg
    560.00€
    5mg
    1,198.00€
    10mg
    1,611.00€
    25mg
    2,385.00€
    50mg
    3,222.00€
  • PPACK II

    CAS:
    PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .
    Formula:C25H33ClN6O3
    Color and Shape:Solid
    Molecular weight:501.02

    Ref: TM-T73863

    5mg
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    50mg
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  • PSI-7409

    CAS:

    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).

    Formula:C10H16FN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.16

    Ref: TM-T12572

    25mg
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    50mg
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    100mg
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  • Dutogliptin tartrate

    CAS:
    Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C14H26BN3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.18

    Ref: TM-T11127

    25mg
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  • Linagliptin Methyldimer

    CAS:
    Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
    Formula:C50H56N16O4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:945.08

    Ref: TM-T67852

    1mg
    115.00€
    2mg
    166.00€
    5mg
    274.00€
    10mg
    406.00€
    25mg
    663.00€
    50mg
    919.00€
    100mg
    1,216.00€
  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
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    50mg
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  • MK-6169

    CAS:
    MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.
    Formula:C54H62FN9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1016.2

    Ref: TM-T24476

    25mg
    1,369.00€
  • Nostosin G


    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T75647

    5mg
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    50mg
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  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • Befovacimab

    CAS:
    Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.
    Color and Shape:Liquid

    Ref: TM-T76921

    5mg
    To inquire