
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(110 products)
- DPP-4(23 products)
- Glutaminase(44 products)
- HIV Protease(495 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(88 products)
- Serine Protease(51 products)
- p97(15 products)
Show 3 more subcategories
Found 993 products of "Proteases/Proteasome"
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Diethyl pyimDC
CAS:Diethyl pyimDC is an inhibitor of human collagen prolyl 4-hydroxylase 1 (CP4H1).Formula:C14H15N3O4Color and Shape:SolidMolecular weight:289.29Tyrosinase-IN-6
CAS:Tyrosinase-IN-6 (4B) is a potent tyrosinase inhibitor (IC50=3.80 μM) with good antioxidant activity.Formula:C24H31N3O2Color and Shape:SolidMolecular weight:393.52Aldumastat
CAS:Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.Formula:C20H24F2N4O3Purity:99.87%Color and Shape:SolidMolecular weight:406.43Garvagliptin
CAS:Garvagliptin has antidiabetic activity.Formula:C18H23F2N3O3SPurity:98%Color and Shape:SolidMolecular weight:399.46Alicapistat
CAS:Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).Formula:C25H27N3O4Purity:98%Color and Shape:SolidMolecular weight:433.5ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99NNGH
CAS:NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.Formula:C13H20N2O5SPurity:98.41%Color and Shape:SolidMolecular weight:316.37VEL-0230
CAS:VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.Formula:C14H24NNaO5Color and Shape:SolidMolecular weight:309.33MK-4882
CAS:MK-4882 is an effective inhibitor of HCV NS5A.Formula:C42H50N8O7Purity:98%Color and Shape:SolidMolecular weight:778.9PK44 phosphate
CAS:PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).Formula:C17H19F5N7O5PColor and Shape:SolidMolecular weight:527.349BAY8040
CAS:BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.Formula:C21H16F3N5O2Color and Shape:SolidMolecular weight:427.38SA 152
CAS:SA 152 is an organophosphoric inhibitor.Formula:C19H12F12NO2PColor and Shape:SolidMolecular weight:545.26AA10 TG2 inhibitor
CAS:AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).Formula:C32H36N4O5Color and Shape:SolidMolecular weight:556.65DPP-4-IN-1
CAS:DPP-4-IN-1 inhibits DPP-4 with 49 nM IC50, ideal for diabetes study, akin to Alogliptin.Formula:C19H19ClN6Color and Shape:SolidMolecular weight:366.85ACH-806
CAS:ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.Formula:C19H20F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:411.44CAY10704
CAS:CAY10704: Potent HCV inhibitor, EC50=17 nM, low cytotoxicity, good in mice, liver-targeted, not hepatotoxic, weak against dengue.Formula:C18H20Cl2N2Color and Shape:SolidMolecular weight:335.27ASPER-29
CAS:ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.Formula:C31H29BrN2O5SColor and Shape:SolidMolecular weight:621.54Sortin1
CAS:Sortin1, a chemical genetic-hit compound, specifically induces mislocalization of both soluble and membrane-associated vacuolar markers in plants and yeast.Formula:C26H19NO6Purity:98%Color and Shape:SolidMolecular weight:441.43MDK7677
CAS:MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.Formula:C12H10N4O3Color and Shape:SolidMolecular weight:258.23Furaprofen
CAS:Furaprofen is an HCV inhibitor with anti-inflammatory activity that inhibits carrageenan-induced paw edema in rats.Formula:C17H14O3Purity:98.49% - 99.52%Color and Shape:SolidMolecular weight:266.29
