
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(110 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(496 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(87 products)
- Serine Protease(51 products)
- p97(15 products)
Show 3 more subcategories
Found 992 products of "Proteases/Proteasome"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tyrosinase-IN-5
CAS:Tyrosinase-IN-5 (16c) inhibits tyrosinase with 0.02 μM IC50, reduces melanogenesis, and is low-toxicity.Formula:C18H13N3O6Color and Shape:SolidMolecular weight:367.31BRD-8899
CAS:BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].Formula:C17H22N4O3SColor and Shape:SolidMolecular weight:362.45APC-366 HCl
CAS:APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.Formula:C22H29ClN6O4Color and Shape:SolidMolecular weight:476.96HCV-IN-36
CAS:HCV-IN-36: oral HCV inhibitor, EC50 0.016 μM, CC50 8.78 μM, potent antiviral.Formula:C30H36ClN5Color and Shape:SolidMolecular weight:502.09GLS1 Inhibitor-3
CAS:GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.Formula:C30H32N10O2SColor and Shape:SolidMolecular weight:596.71AK 275
CAS:AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.Formula:C20H31N3O4Color and Shape:SolidMolecular weight:377.48MMP-2/9-IN-1
CAS:MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.Formula:C14H16IN7SColor and Shape:SolidMolecular weight:441.29AZD-9684
CAS:AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.Formula:C10H14N2O2SColor and Shape:SolidMolecular weight:226.3(R)-ND-336
CAS:(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.Formula:C16H18ClNO3S2Color and Shape:SolidMolecular weight:371.89L-873724
CAS:L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.Formula:C23H26F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:481.53ITX-4520
CAS:ITX-4520 novel highly potent, orally bioavailable inhibitor of hepatitis C virus (HCV) entry.Formula:C24H23F2N3OSColor and Shape:SolidMolecular weight:439.52JO146
CAS:JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。Formula:C31H44N3O7PColor and Shape:SolidMolecular weight:601.67GM 1489
CAS:GM 1489 is an MMP inhibitor, effective against MMP-1, -2, -3, -8, -9, reduces cancer cell invasion, and prevents ear thickening in mice.Formula:C27H33N3O4Color and Shape:SolidMolecular weight:463.57L 722151
CAS:L 722151 is an FXIIIa inhibitor.Formula:C8H9ClN2O5S3Purity:98%Color and Shape:SolidMolecular weight:344.82Immunoproteasome inhibitor 1
CAS:Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.Formula:C20H26N2O4Color and Shape:SolidMolecular weight:358.43CAA0225
CAS:CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.Formula:C28H29N3O5Color and Shape:SolidMolecular weight:487.55PF-00356231 hydrochloride
CAS:PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.Formula:C25H21ClN2O3SPurity:98.39%Color and Shape:SolidMolecular weight:464.96MDL 27399
CAS:MDL 27399 suppresses human neutrophil cathepsin G.Formula:C26H36N4O8Color and Shape:SolidMolecular weight:532.59Chymase-IN-1
CAS:Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).Formula:C20H15ClNO4PSPurity:99.17%Color and Shape:SolidMolecular weight:431.83Ref: TM-T10811
1mg155.00€5mg369.00€10mg525.00€25mg787.00€50mg1,054.00€100mg1,415.00€500mg2,802.00€1mL*10mM (DMSO)404.00€AM 4299 B
CAS:AM 4299 B is a novel inhibitor of a thiol protease.Formula:C16H27N3O7Purity:98%Color and Shape:SolidMolecular weight:373.4
