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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 992 products of "Proteases/Proteasome"

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  • Tyrosinase-IN-5

    CAS:
    Tyrosinase-IN-5 (16c) inhibits tyrosinase with 0.02 μM IC50, reduces melanogenesis, and is low-toxicity.
    Formula:C18H13N3O6
    Color and Shape:Solid
    Molecular weight:367.31

    Ref: TM-T61425

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • BRD-8899

    CAS:
    BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].
    Formula:C17H22N4O3S
    Color and Shape:Solid
    Molecular weight:362.45

    Ref: TM-T61361

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • APC-366 HCl

    CAS:
    APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.
    Formula:C22H29ClN6O4
    Color and Shape:Solid
    Molecular weight:476.96

    Ref: TM-T70193

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • HCV-IN-36

    CAS:
    HCV-IN-36: oral HCV inhibitor, EC50 0.016 μM, CC50 8.78 μM, potent antiviral.
    Formula:C30H36ClN5
    Color and Shape:Solid
    Molecular weight:502.09

    Ref: TM-T63407

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • GLS1 Inhibitor-3

    CAS:
    GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.
    Formula:C30H32N10O2S
    Color and Shape:Solid
    Molecular weight:596.71

    Ref: TM-T64211

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AK 275

    CAS:
    AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.
    Formula:C20H31N3O4
    Color and Shape:Solid
    Molecular weight:377.48

    Ref: TM-T25009

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MMP-2/9-IN-1

    CAS:
    MMP-2/9-IN-1 (Compound 4a) is a potent dual inhibitor of MMP-2 (IC50: 56 nM) and MMP-9 (IC50: 38 nM). leading to DNA fragmentation.
    Formula:C14H16IN7S
    Color and Shape:Solid
    Molecular weight:441.29

    Ref: TM-T62555

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • AZD-9684

    CAS:
    AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.
    Formula:C10H14N2O2S
    Color and Shape:Solid
    Molecular weight:226.3

    Ref: TM-T26725

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • (R)-ND-336

    CAS:
    (R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.
    Formula:C16H18ClNO3S2
    Color and Shape:Solid
    Molecular weight:371.89

    Ref: TM-T61491

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • L-873724

    CAS:
    L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.
    Formula:C23H26F3N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.53

    Ref: TM-T16092

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • ITX-4520

    CAS:
    ITX-4520 novel highly potent, orally bioavailable inhibitor of hepatitis C virus (HCV) entry.
    Formula:C24H23F2N3OS
    Color and Shape:Solid
    Molecular weight:439.52

    Ref: TM-T27641

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • JO146

    CAS:
    JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。
    Formula:C31H44N3O7P
    Color and Shape:Solid
    Molecular weight:601.67

    Ref: TM-T73532

    25mg
    1,224.00€
    50mg
    1,594.00€
    100mg
    2,250.00€
  • GM 1489

    CAS:
    GM 1489 is an MMP inhibitor, effective against MMP-1, -2, -3, -8, -9, reduces cancer cell invasion, and prevents ear thickening in mice.
    Formula:C27H33N3O4
    Color and Shape:Solid
    Molecular weight:463.57

    Ref: TM-T37983

    1mg
    239.00€
    5mg
    1,108.00€
  • L 722151

    CAS:
    L 722151 is an FXIIIa inhibitor.
    Formula:C8H9ClN2O5S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:344.82

    Ref: TM-T24349

    25mg
    1,783.00€
  • Immunoproteasome inhibitor 1

    CAS:
    Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.
    Formula:C20H26N2O4
    Color and Shape:Solid
    Molecular weight:358.43

    Ref: TM-T61320

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CAA0225

    CAS:
    CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.
    Formula:C28H29N3O5
    Color and Shape:Solid
    Molecular weight:487.55

    Ref: TM-T26938

    25mg
    1,783.00€
  • PF-00356231 hydrochloride

    CAS:
    PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.
    Formula:C25H21ClN2O3S
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:464.96

    Ref: TM-T12414

    1mg
    67.00€
    5mg
    177.00€
    10mg
    284.00€
    25mg
    464.00€
    50mg
    642.00€
    100mg
    853.00€
    500mg
    To inquire
  • MDL 27399

    CAS:
    MDL 27399 suppresses human neutrophil cathepsin G.
    Formula:C26H36N4O8
    Color and Shape:Solid
    Molecular weight:532.59

    Ref: TM-T25783

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Chymase-IN-1

    CAS:
    Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
    Formula:C20H15ClNO4PS
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:431.83

    Ref: TM-T10811

    1mg
    155.00€
    5mg
    369.00€
    10mg
    525.00€
    25mg
    787.00€
    50mg
    1,054.00€
    100mg
    1,415.00€
    500mg
    2,802.00€
    1mL*10mM (DMSO)
    404.00€
  • AM 4299 B

    CAS:
    AM 4299 B is a novel inhibitor of a thiol protease.
    Formula:C16H27N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.4

    Ref: TM-T25068

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€