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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 992 products of "Proteases/Proteasome"

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  • BMS-212122

    CAS:
    BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.
    Formula:C43H36F6N4O2
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:754.76

    Ref: TM-T30506

    1mg
    315.00€
    5mg
    745.00€
    10mg
    1,018.00€
    25mg
    1,431.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
    500mg
    4,410.00€
  • ZED-1227

    CAS:

    ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas

    Formula:C26H36N6O6
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:528.6

    Ref: TM-T17289

    1mg
    248.00€
    5mg
    553.00€
    10mg
    847.00€
    25mg
    1,549.00€
    50mg
    2,670.00€
  • VBY-825

    CAS:
    VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
    Formula:C23H29F4N3O5S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:535.55

    Ref: TM-T13288

    1mg
    250.00€
    2mg
    371.00€
    5mg
    620.00€
    10mg
    882.00€
    25mg
    1,314.00€
    50mg
    1,765.00€
    100mg
    2,385.00€
  • Napsagatran hydrate

    CAS:
    Napsagatran hydrate is a novel and specific inhibitor of thrombin.
    Formula:C26H36N6O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.66

    Ref: TM-T16273

    25mg
    To inquire
    50mg
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    100mg
    To inquire
  • GLS-1-IN-1


    GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
    Formula:C26H25FN4OS
    Color and Shape:Solid
    Molecular weight:460.57

    Ref: TM-T62905

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Odiparcil

    CAS:
    Odiparcil is an orally active beta-d-thioxyloside analog.
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35

    Ref: TM-T16377

    2mg
    161.00€
    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,386.00€
  • ZINC09518833

    CAS:
    ZINC09518833 is an α-ketoamide non-peptide proteasome inhibitor with an IC50 value of 12.4 μM. It can bind with both the active and inactive sites of the proteasome. ZINC09518833 shows promise for use in research related to multiple myeloma (MM).
    Formula:C24H25N3O5
    Color and Shape:Solid
    Molecular weight:435.47

    Ref: TM-T200622

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • PLGLAG

    CAS:
    PLGLAG is a peptide chain that acts as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the PLGLAG linker are primarily sensitive to MMP-2 and MMP-9 in vivo. PLGLAG is applicable in cancer research.
    Formula:C24H42N6O7
    Color and Shape:Solid
    Molecular weight:526.63

    Ref: TM-TP3961

    10mg
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    50mg
    To inquire
  • Tyrosinase-IN-37

    CAS:
    Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.
    Formula:C12H12N6S
    Color and Shape:Solid
    Molecular weight:272.33

    Ref: TM-T200626

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tyrosinase-IN-33

    CAS:
    Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.
    Formula:C19H17NS2
    Color and Shape:Solid
    Molecular weight:323.48

    Ref: TM-T200002

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • GB111-NH2

    CAS:
    GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].
    Formula:C33H39N3O6
    Color and Shape:Solid
    Molecular weight:573.68

    Ref: TM-T86493

    10mg
    To inquire
    50mg
    To inquire
  • Verducatib

    CAS:
    Verducatib is an inhibitor of cathepsins (cathepsin).
    Formula:C31H35FN4O3
    Color and Shape:Solid
    Molecular weight:530.633

    Ref: TM-T205396

    10mg
    To inquire
    50mg
    To inquire
  • MMP-13-IN-1

    CAS:
    MMP-13-IN-1, with an IC50 value of 16 nM, is a potent and selective inhibitor of MMP-13, suitable for atherosclerosis research [1].
    Formula:C19H16F3N3O3
    Color and Shape:Solid
    Molecular weight:391.34

    Ref: TM-T86912

    10mg
    To inquire
    50mg
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  • JBJ-08-178-01

    CAS:
    JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.
    Formula:C31H30N8O3
    Color and Shape:Solid
    Molecular weight:562.62

    Ref: TM-T200308

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AEP-IN-1


    APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.
    Formula:C18H27N3O3
    Color and Shape:Solid
    Molecular weight:333.43

    Ref: TM-T61004

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RIPK1-IN-26

    CAS:
    RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.
    Formula:C15H20FNO2
    Color and Shape:Solid
    Molecular weight:265.32

    Ref: TM-T200690

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • BAY-7598

    CAS:
    BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).
    Formula:C28H31N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.56

    Ref: TM-T10474

    25mg
    3,348.00€
    50mg
    4,213.00€
    100mg
    5,580.00€
  • GW311616 hydrochloride

    CAS:
    GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
    Formula:C19H32ClN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.99

    Ref: TM-T11525L

    1mg
    273.00€
    5mg
    818.00€
    10mg
    1,359.00€
  • BMT-052

    CAS:
    BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).
    Formula:C30H17D9F4N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:635.61

    Ref: TM-T26871

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • HsClpP activator-1

    CAS:
    HsClpP activator-1 (compound 24) is a potent activator of HsClpP, with an EC50 of 0.22 μM. It effectively inhibits cancer cell growth, exhibiting IC50 values ranging from 0.1 to 1 μM.
    Formula:C23H20F5N3O2
    Color and Shape:Solid
    Molecular weight:465.42

    Ref: TM-T210884

    10mg
    To inquire
    50mg
    To inquire