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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 992 products of "Proteases/Proteasome"

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  • SSR-182289A (Free)

    CAS:
    SSR-182289A (Free) is a thrombin inhibitor.
    Formula:C30H33F2N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:597.68

    Ref: TM-T28857

    25mg
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    50mg
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    100mg
    To inquire
  • AMG-222 tosylate

    CAS:
    AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.
    Formula:C39H47N9O6S
    Color and Shape:Solid
    Molecular weight:769.91

    Ref: TM-T71354

    25mg
    3,866.00€
    50mg
    5,111.00€
    100mg
    7,220.00€
  • Duazomycin sodium

    CAS:
    Duazomycin (Duazomycin A) sodium acts as a glutamine antagonist. It significantly enhances the efficacy of 6-Mercaptopurine (6-MP) in treating experimental autoimmune encephalomyelitis (EAE) without increasing toxicity.
    Formula:C8H10N3NaO4
    Color and Shape:Solid
    Molecular weight:235.17

    Ref: TM-T211286

    10mg
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    50mg
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  • NAPAP

    CAS:
    NAPAP is a thrombin inhibitor with potent anticoagulant activity (Ki: 2.1 nM). It selectively inhibits thrombin through a rapid binding mechanism while exhibiting weaker inhibition of trypsin, Factor Xa, and plasmin. NAPAP can be utilized for research into thrombotic conditions, including venous thrombosis and myocardial infarction.
    Formula:C27H31N5O4S
    Color and Shape:Solid
    Molecular weight:521.63

    Ref: TM-T210606

    10mg
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    50mg
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  • Faldaprevir

    CAS:
    Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.
    Formula:C40H49BrN6O9S
    Purity:99.04% - 99.19%
    Color and Shape:Solid
    Molecular weight:869.82

    Ref: TM-T19685

    1mg
    250.00€
    5mg
    610.00€
    10mg
    853.00€
    25mg
    1,243.00€
  • CM-352

    CAS:
    CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.
    Formula:C24H29N3O6S
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:487.57

    Ref: TM-T70470

    1mg
    374.00€
    5mg
    793.00€
    10mg
    973.00€
    25mg
    1,279.00€
  • Beclabuvir

    CAS:
    Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.
    Formula:C36H45N5O5S
    Purity:99.87% - 99.93%
    Color and Shape:Solid
    Molecular weight:659.84

    Ref: TM-T10493

    1mg
    128.00€
  • Cyclophilin inhibitor 1

    CAS:
    Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.
    Formula:C31H39N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:593.67

    Ref: TM-T10919

    25mg
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    50mg
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    100mg
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  • ABT-072

    CAS:
    ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.
    Formula:C24H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.55

    Ref: TM-T14086

    25mg
    1,691.00€
    50mg
    2,205.00€
    100mg
    3,345.00€
  • Cathepsin C-IN-5

    CAS:

    Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.

    Formula:C21H17ClN6OS
    Color and Shape:Solid
    Molecular weight:436.92

    Ref: TM-T62494

    25mg
    812.00€
    50mg
    1,054.00€
    100mg
    1,529.00€
  • Tyrosinase-IN-35

    CAS:
    Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.
    Formula:C17H15N5OS
    Color and Shape:Solid
    Molecular weight:337.40

    Ref: TM-T200078

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Feniralstat

    CAS:
    Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.
    Formula:C26H25F2N5O4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:509.51

    Ref: TM-T63507

    1mg
    178.00€
    5mg
    467.00€
    10mg
    668.00€
    25mg
    1,369.00€
    50mg
    1,783.00€
    1mL*10mM (DMSO)
    532.00€
  • Pyridoxatin

    CAS:
    Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.
    Formula:C15H21NO3
    Color and Shape:Solid
    Molecular weight:263.33

    Ref: TM-T70891

    1mg
    298.00€
    500µg
    178.00€
  • HCV-IN-7

    CAS:
    HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H48N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:768.92

    Ref: TM-T11548

    25mg
    2,313.00€
    50mg
    3,042.00€
    100mg
    4,140.00€
  • Idraparinux Na

    CAS:
    Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor
    Formula:C38H55Na9O49S7
    Color and Shape:Solid
    Molecular weight:1727.14

    Ref: TM-T70536

    25mg
    6,094.00€
    50mg
    8,082.00€
    100mg
    11,700.00€
  • Freselestat quarterhydrate


    ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.
    Formula:C23H30N6O5
    Color and Shape:Solid
    Molecular weight:457.03

    Ref: TM-T62846

    25mg
    1,026.00€
    50mg
    1,341.00€
    100mg
    2,052.00€
  • Faldaprevir sodium

    CAS:
    Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.
    Formula:C40H48BrN6NaO9S
    Color and Shape:Solid
    Molecular weight:891.81

    Ref: TM-T71215

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Tyrosinase-IN-29

    CAS:
    Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.
    Formula:C10H9NO2
    Color and Shape:Solid
    Molecular weight:175.18

    Ref: TM-T88534

    10mg
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    50mg
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  • Anti-infective agent 10

    CAS:
    Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.
    Formula:C26H25N3O7S
    Color and Shape:Solid
    Molecular weight:523.56

    Ref: TM-T207374

    10mg
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    50mg
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  • DPP-4-IN-15

    CAS:
    DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.
    Formula:C17H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:381.372

    Ref: TM-T205036

    10mg
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    50mg
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