CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 1045 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Enantiomer of Sofosbuvir


    <p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45
  • BI-1915

    CAS:
    <p>BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.</p>
    Formula:C21H37N5O3
    Color and Shape:Solid
    Molecular weight:407.55
  • Deleobuvir

    CAS:
    <p>Deleobuvir(BI207127) is an inhibitor of non-nucleoside hepatitis C virus NS5B polymerase for the treatment of hepatitis C.</p>
    Formula:C34H33BrN6O3
    Color and Shape:Solid
    Molecular weight:653.57
  • Plasma kallikrein-IN-2


    <p>Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.</p>
    Formula:C28H24ClF3N8O3
    Color and Shape:Solid
    Molecular weight:612.99
  • Valopicitabine dihydrochloride

    CAS:
    <p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>
    Formula:C15H25ClN4O6
    Color and Shape:Solid
    Molecular weight:392.84
  • Cathepsin C-IN-4


    <p>Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).</p>
    Formula:C21H14ClF3N4S
    Color and Shape:Solid
    Molecular weight:446.88
  • SMCypI C31


    <p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>
    Formula:C27H30N4O2S
    Color and Shape:Solid
    Molecular weight:474.62
  • (1R,3S)-THCCA-Asn


    <p>(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.</p>
    Formula:C24H24N4O6
    Color and Shape:Solid
    Molecular weight:464.47
  • RO5461111

    CAS:
    <p>RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) &amp; 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation &amp; lupus nephritis.</p>
    Formula:C27H24F6N4O4S
    Color and Shape:Solid
    Molecular weight:614.56
  • CE-2072

    CAS:
    <p>CE-2072 is a synthetic host serine proteases inhibitor.</p>
    Formula:C33H41N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.71
  • Antiplatelet agent 3

    CAS:
    <p>Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.</p>
    Formula:C38H32N2O5
    Color and Shape:Solid
    Molecular weight:596.671
  • Cathepsin C-IN-3


    <p>Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).</p>
    Formula:C28H21F3N6OS
    Color and Shape:Solid
    Molecular weight:546.57
  • Zetomipzomib

    CAS:
    <p>KZR-616: Immunoproteasome inhibitor targeting LMP7 (IC50: 39/57 nM) &amp; LMP2 (IC50: 131/179 nM), potential in autoimmune disease research.</p>
    Formula:C30H42N4O8
    Color and Shape:Solid
    Molecular weight:586.68
  • Human enteropeptidase-IN-2


    <p>Human enteropeptidase-IN-2 is a potent inhibitor of enteropeptidase (enteropeptidase) and can be used in anti-obesity studies.</p>
    Formula:C20H19F3N4O7
    Color and Shape:Solid
    Molecular weight:484.38
  • SD-2590 HCl

    CAS:
    <p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>
    Formula:C22H26ClF3N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.96
  • SBI-581


    <p>SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.</p>
    Formula:C24H21N3O2
    Color and Shape:Solid
    Molecular weight:383.44
  • TG-2-IN-4

    CAS:
    <p>TG-2-IN-4 (compound 8), an inhibitor of transglutaminase 2 (TG2) with an IC 50 value of less than 0.5 mM, is utilized in the study of inflammatory disorders [1].</p>
    Formula:C34H40N6O5
    Color and Shape:Solid
    Molecular weight:612.72
  • Faldaprevir

    CAS:
    <p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>
    Formula:C40H49BrN6O9S
    Purity:99.04% - 99.19%
    Color and Shape:Solid
    Molecular weight:869.82
  • HCV-IN-38


    <p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>
    Formula:C22H24ClF3N4O4
    Color and Shape:Solid
    Molecular weight:500.9
  • SAR107375

    CAS:
    <p>SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].</p>
    Formula:C24H30ClN5O5S2
    Color and Shape:Solid
    Molecular weight:568.11