
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(36 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(501 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 994 products of "Proteases/Proteasome"
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PF 00356231
CAS:PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
Formula:C25H20N2O3SPurity:99.35%Color and Shape:SolidMolecular weight:428.5Calpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formula:C19H17FN6O5SColor and Shape:SolidMolecular weight:460.44Grazoprevir potassium salt
CAS:Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.
Formula:C38H49KN6O9SColor and Shape:SolidMolecular weight:805APC-6860
CAS:APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.Formula:C9H7IN2SColor and Shape:SolidMolecular weight:302.13PROTAC CG167
PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)Formula:C65H79N13O11SColor and Shape:SolidMolecular weight:1250.47N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formula:C33H36N6O6Purity:98%Color and Shape:White To Off-White PowderMolecular weight:612.68Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS:Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormula:C26H36ClN7O7SColor and Shape:SolidMolecular weight:626.12Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFormula:C24H35N5O4·xC2HF3O2Color and Shape:SolidBPHA
CAS:BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.Formula:C21H20N2O4SPurity:99.44%Color and Shape:SolidMolecular weight:396.46Ref: TM-T36712
1mg167.00€5mg442.00€10mg620.00€25mg954.00€50mg1,305.00€100mg1,738.00€200mg2,322.00€1mL*10mM (DMSO)442.00€Ala-Phe-Pro-pNA TFA
Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.Color and Shape:Odour SolidPlasma kallikrein-IN-1
CAS:Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.Formula:C23H25F2N7OColor and Shape:SolidMolecular weight:453.498Obtusifolin-2-O-glucoside
CAS:Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].Formula:C22H22O10Color and Shape:SolidMolecular weight:446.4LXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
Formula:C27H22FN7O6Purity:99.89%Color and Shape:SoildMolecular weight:559.51NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formula:C62H111N11O12Purity:98%Color and Shape:SolidMolecular weight:1202.635JC-10
CAS:JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.Formula:C25H29Cl2IN4Purity:95%Color and Shape:SolidMolecular weight:583.34Aristololactam IIIa
CAS:Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.Formula:C16H9NO4Color and Shape:SolidMolecular weight:279.25Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.Formula:C21H24O8Color and Shape:SolidMolecular weight:404.415BAY 1217224
CAS:BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.
Formula:C24H27ClFN3O5Color and Shape:SolidMolecular weight:491.94Monodes(N-carboxymethyl)valine Daclatasvir
CAS:Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.Formula:C33H39N7O3Color and Shape:SolidMolecular weight:581.71Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Formula:C10H23BN2O6SPurity:98%Color and Shape:SolidMolecular weight:310.18

