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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 994 products of "Proteases/Proteasome"

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  • PF 00356231

    CAS:

    PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).

    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    185.00€
    5mg
    415.00€
    10mg
    622.00€
    25mg
    1,119.00€
    50mg
    1,679.00€
    100mg
    2,520.00€
    200mg
    3,780.00€
  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • Grazoprevir potassium salt

    CAS:

    Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.

    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805

    Ref: TM-T19948

    50mg
    To inquire
    100mg
    To inquire
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13

    Ref: TM-T39029

    5mg
    873.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
    To inquire
    500mg
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  • Dansyl-Glu-Gly-Arg-Chloromethylketone

    CAS:
    Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated
    Formula:C26H36ClN7O7S
    Color and Shape:Solid
    Molecular weight:626.12

    Ref: TM-T80094

    5mg
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    50mg
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  • Cathepsin C-IN-6


    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T79496

    5mg
    To inquire
    50mg
    To inquire
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T36712

    1mg
    167.00€
    5mg
    442.00€
    10mg
    620.00€
    25mg
    954.00€
    50mg
    1,305.00€
    100mg
    1,738.00€
    200mg
    2,322.00€
    1mL*10mM (DMSO)
    442.00€
  • Ala-Phe-Pro-pNA TFA


    Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.
    Color and Shape:Odour Solid

    Ref: TM-TXB-00595

    10mg
    To inquire
    50mg
    To inquire
  • Plasma kallikrein-IN-1

    CAS:
    Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
    Formula:C23H25F2N7O
    Color and Shape:Solid
    Molecular weight:453.498

    Ref: TM-T40312

    5mg
    873.00€
  • Obtusifolin-2-O-glucoside

    CAS:
    Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].
    Formula:C22H22O10
    Color and Shape:Solid
    Molecular weight:446.4

    Ref: TM-T75572

    5mg
    To inquire
    50mg
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  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.

    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    315.00€
    2mg
    472.00€
    5mg
    595.00€
    10mg
    947.00€
    25mg
    1,396.00€
    50mg
    1,890.00€
    100mg
    2,547.00€
  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • JC-10

    CAS:
    JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34

    Ref: TM-TD0056

    1mg
    118.00€
  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
    To inquire
    50mg
    To inquire
  • Nitidanin


    Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415

    Ref: TM-T125599

    1mg
    To inquire
    5mg
    To inquire
  • BAY 1217224

    CAS:

    BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.

    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94

    Ref: TM-T39124

    25mg
    7,590.00€
  • Monodes(N-carboxymethyl)valine Daclatasvir

    CAS:
    Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.
    Formula:C33H39N7O3
    Color and Shape:Solid
    Molecular weight:581.71

    Ref: TM-T37915

    5mg
    299.00€
    10mg
    507.00€
  • Talabostat isomer mesylate


    Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).
    Formula:C10H23BN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.18

    Ref: TM-T13069

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire