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Stem Cell and Derivatives

Stem Cell and Derivatives

Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.

Subcategories of "Stem Cell and Derivatives"

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Found 693 products of "Stem Cell and Derivatives"

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  • Casein kinase 1δ-IN-7
    Targetmol
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    Casein kinase 1δ-IN-7

    CAS:
    <p>Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.</p>
    Formula:C17H14N4O2S
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:338.38

    Ref: TM-T77708

  • SJ1008030
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    SJ1008030

    CAS:
    <p>SJ1008030, a JAK2 PROTAC, degrades JAK2; EC50: 5.4 nM, IC50: 32.09 nM in MHH-CALL-4 cells for leukemia research.</p>
    Formula:C42H43N13O7S
    Color and Shape:Solid
    Molecular weight:873.94

    Ref: TM-T74580

  • JAK1/TYK2-IN-1
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    JAK1/TYK2-IN-1

    CAS:
    <p>JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).</p>
    Formula:C18H20F3N7O
    Color and Shape:Solid
    Molecular weight:407.401

    Ref: TM-T39314

  • YAP/TEAD-IN-1
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    YAP/TEAD-IN-1

    <p>YAP/TEAD-IN-1 (compound 4) is a potent inhibitor of YAP and TEAD, exhibiting antioxidant properties. It demonstrates antiproliferative effects on tumor cells while showing minimal cytotoxic activity towards normal human cells.</p>
    Formula:C32H30N8O
    Color and Shape:Solid
    Molecular weight:542.634

    Ref: TM-T204795

  • FDA-Approved Kinase Inhibitor Library
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    FDA-Approved Kinase Inhibitor Library

    <p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>
    Color and Shape:Liquid

    Ref: TM-L1610

  • Epigenetics Compound Library
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    Epigenetics Compound Library

    <p>Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new</p>
    Color and Shape:Odour Solid

    Ref: TM-L1200

  • CIA-1 (Free base)
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    CIA-1 (Free base)

    CAS:
    <p>CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.</p>
    Formula:C17H19N3O2S
    Purity:99%
    Color and Shape:Solid
    Molecular weight:329.42

    Ref: TM-T71534L

  • Tyrosine Kinase Inhibitor Library
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    Tyrosine Kinase Inhibitor Library

    <p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>
    Color and Shape:Odour Solid

    Ref: TM-L2200

  • Kinase Inhibitor Library
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    Kinase Inhibitor Library

    <p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>
    Color and Shape:Odour Solid

    Ref: TM-L1600

  • CymitQuimica logo
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    YAP-IN-1

    <p>YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206234

  • SJ10542
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    SJ10542

    CAS:
    <p>SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.</p>
    Formula:C41H46N12O5S
    Color and Shape:Solid
    Molecular weight:818.95

    Ref: TM-T74429

  • FRM-024
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    FRM-024

    CAS:
    <p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>
    Formula:C22H22ClN5O2
    Color and Shape:Solid
    Molecular weight:423.9

    Ref: TM-T39492

  • 1(R),2(S)-epoxy Cannabidiol
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    1(R),2(S)-epoxy Cannabidiol

    CAS:
    <p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>
    Formula:C21H30O3
    Color and Shape:Solid
    Molecular weight:330.46

    Ref: TM-T203031

  • Foxy-5 Ammonium Salt
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    Foxy-5 Ammonium Salt

    <p>Foxy-5 Ammonium Salt, a WNT5A mimetic, blocks epithelial cancer cell migration without β-catenin impact and curbs prostate cancer spread.</p>
    Formula:C26H46N7O12S2
    Purity:97.70%
    Color and Shape:Solid
    Molecular weight:712.26

    Ref: TM-TP1565L1

  • YAP-TEAD-IN-1 acetate
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    YAP-TEAD-IN-1 acetate

    <p>YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.</p>
    Formula:C95H148ClN23O23S2
    Purity:98.11% - 99.57%
    Color and Shape:Soild
    Molecular weight:2079.92

    Ref: TM-TP2160L1

  • Carboxylesterase-IN-2
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    Carboxylesterase-IN-2

    CAS:
    <p>Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 &lt;= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.</p>
    Formula:C13H12N4OS
    Purity:99.92%
    Color and Shape:Soild
    Molecular weight:272.33

    Ref: TM-T77524

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    Fresolimumab

    CAS:
    <p>Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.</p>
    Purity:> 95% - > 95%
    Color and Shape:Liquid
    Molecular weight:144.4 kDa

    Ref: TM-T76681

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    TEAD-IN-19

    <p>TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, showing inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% for TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at 10 μM. It exhibits strong antiproliferative and antimigratory effects on prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds potential for research in the field of cancer therapeutics.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206604

  • Notch 1 TFA
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    Notch 1 TFA

    <p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>
    Formula:C64H98N15F3O25S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1614.81

    Ref: TM-T19483

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    LH168

    <p>LH168 is a potent and selective probe for WDR5, with a SPR Kd value of 13 nM.</p>
    Formula:C29H31F3N6O2S
    Color and Shape:Solid
    Molecular weight:584.66

    Ref: TM-T205103