Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
Subcategories of "Stem Cell and Derivatives"
- Gamma-secretase(67 products)
- Hedgehog/Smoothened(49 products)
- Hippo pathway(7 products)
- JAK(245 products)
- Porcupine(8 products)
- ROCK(62 products)
- STAT(105 products)
- Stem Cells(129 products)
- TGF-beta/Smad(70 products)
- Wnt/beta-catenin(65 products)
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Found 436 products for "Stem Cell and Derivatives".
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GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:99.75%Color and Shape:White SolidMolecular weight:612.03Ref: TM-T9826
1mg93.00€5mg182.00€1mL*10mM (DMSO)245.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formula:C24H24N6O2Purity:98.44%Color and Shape:SolidMolecular weight:428.49Ref: TM-T5091
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)107.00€10mg128.00€25mg212.00€50mg319.00€100mg485.00€JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purity:98% - 99.81%Color and Shape:SolidMolecular weight:297.31WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formula:C28H32N4O3·xClHColor and Shape:SolidPeficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purity:98.67% - 99.89%Color and Shape:SolidMolecular weight:326.39Ref: TM-T6933
2mg38.00€5mg63.00€1mL*10mM (DMSO)70.00€10mg99.00€25mg172.00€50mg268.00€100mg416.00€200mg610.00€Cucurbitacin I
CAS:Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.Formula:C30H42O7Purity:96.69% - 99.8%Color and Shape:SolidMolecular weight:514.65Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34Ref: TM-T3080
1mg50.00€2mg71.00€5mg105.00€1mL*10mM (DMSO)110.00€10mg173.00€25mg358.00€50mg587.00€100mg888.00€200mg1,198.00€Lumiflavine
CAS:Lumiflavine (Lumilactoflavin) inhibits riboflavin uptake. It is produced by the photolysis of vitamin B2.Formula:C13H12N4O2Purity:97.09% - 98.01%Color and Shape:Yellow SolidMolecular weight:256.26XMU-MP-1
CAS:XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!Formula:C17H16N6O3S2Purity:99.68% - 99.97%Color and Shape:SolidMolecular weight:416.48Ref: TM-T4212
1mg50.00€2mg74.00€1mL*10mM (DMSO)89.00€5mg92.00€10mg144.00€25mg289.00€50mg485.00€100mg628.00€ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05% - 99.48%Color and Shape:White SolidMolecular weight:367.91SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H32ClN3OPurity:99.32% - 99.41%Color and Shape:SolidMolecular weight:365.94Ref: TM-T5129
1mg34.00€2mg44.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg105.00€25mg215.00€50mg334.00€100mg497.00€200mg755.00€2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:White SolidMolecular weight:350.2LY900009
CAS:LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.Formula:C23H27N3O4Purity:97.07%Color and Shape:SolidMolecular weight:409.48Ref: TM-T9015
1mg35.00€5mg80.00€1mL*10mM (DMSO)87.00€10mg112.00€25mg197.00€50mg290.00€100mg420.00€200mg590.00€Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purity:98.52% - >99.99%Color and Shape:SolidMolecular weight:425.46Ref: TM-T14687
1mg56.00€5mg137.00€1mL*10mM (DMSO)149.00€10mg248.00€25mg389.00€50mg575.00€100mg817.00€BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurity:97.69% - 99.97%Color and Shape:SolidMolecular weight:432.52MK-0752 Sodium
CAS:Sodium MK-0752 is a novel and potent gamma-secretase inhibitor that has been evaluated in clinical trials for the treatment of various types of cancer.Formula:C21H21ClF2NaO4SColor and Shape:SolidMolecular weight:465.89BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Formula:C17H13N5Purity:99.87%Color and Shape:SolidMolecular weight:287.32Ref: TM-T8330
1mg48.00€5mg96.00€1mL*10mM (DMSO)131.00€10mg133.00€25mg259.00€50mg371.00€100mg527.00€200mg713.00€FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formula:C28H32O6Purity:97.90% - 99.10%Color and Shape:SolidMolecular weight:464.55Ref: TM-T6838
2mg43.00€5mg63.00€1mL*10mM (DMSO)69.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€Gusacitinib HCl
CAS:Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Formula:C24H29ClN8O2Color and Shape:SolidMolecular weight:497
