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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Oxidopamine hydrobromide

    CAS:
    <p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>
    Formula:C8H12BrNO3
    Purity:98.22% - 99.88%
    Color and Shape:Beige To Brown Fine Crystalline Powder
    Molecular weight:250.09
  • MLi-2

    CAS:
    <p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>
    Formula:C21H25N5O2
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:379.46
  • Cytarabine

    CAS:
    <p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>
    Formula:C9H13N3O5
    Purity:99.83% - 99.93%
    Color and Shape:Fine Off-White Crystalline Powder
    Molecular weight:243.22
  • Mevastatin

    CAS:
    <p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>
    Formula:C23H34O5
    Purity:99.12%
    Color and Shape:White-Yellowish To Yellow Powder Solid Powder
    Molecular weight:390.51
  • Ketanserin

    CAS:
    <p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>
    Formula:C22H22FN3O3
    Purity:99.19% - 99.73%
    Color and Shape:Solid
    Molecular weight:395.43
  • Glibenclamide

    CAS:
    <p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>
    Formula:C23H28ClN3O5S
    Purity:99.05% - 99.75%
    Color and Shape:Solid
    Molecular weight:494.00
  • Thalidomide

    CAS:
    <p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>
    Formula:C13H10N2O4
    Purity:98.88% - 99.88%
    Color and Shape:White Solid
    Molecular weight:258.23
  • Chenodeoxycholic acid

    CAS:
    <p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>
    Formula:C24H40O4
    Purity:99.70% - 99.93%
    Color and Shape:White - Almost White Solid Powder
    Molecular weight:392.57
  • Dexamethasone

    CAS:
    <p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46
  • Phenformin hydrochloride

    CAS:
    <p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>
    Formula:C10H16ClN5
    Purity:97.11% - 99.80%
    Color and Shape:Lactic Acidosis
    Molecular weight:241.72
  • Spironolactone

    CAS:
    <p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>
    Formula:C24H32O4S
    Purity:99.87%
    Color and Shape:White Powder
    Molecular weight:416.57
  • Doxorubicin hydrochloride

    CAS:
    <p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>
    Formula:C27H29NO11·HCl
    Purity:98% - 99.52%
    Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
    Molecular weight:579.99
  • Trimetazidine dihydrochloride

    CAS:
    <p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>
    Formula:C14H24Cl2N2O3
    Purity:99.58%
    Color and Shape:Crystalline Solid
    Molecular weight:339.258
  • Hydroxyurea

    CAS:
    <p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>
    Formula:CH4N2O2
    Purity:99.85% - 99.92%
    Color and Shape:Solid
    Molecular weight:76.05
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Formula:C28H28ClNO4S
    Purity:98% - 99.97%
    Color and Shape:Light Yellow Solid
    Molecular weight:510.044
  • Avermectin B1

    CAS:
    <p>Avermectin B1 is served as anthelmintic and insecticide.</p>
    Formula:C48H72O14
    Purity:mixture - mixture
    Color and Shape:White Powder
    Molecular weight:873.09
  • Doxazosin mesylate

    CAS:
    <p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>
    Formula:C24H29N5O8S
    Purity:99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:547.58
  • Pictilisib dimethanesulfonate

    CAS:
    <p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>
    Formula:C25H35N7O9S4
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:705.85
  • Reserpine

    CAS:
    <p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>
    Formula:C33H40N2O9
    Purity:98.85% - 99.81%
    Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Molecular weight:608.68
  • Lapatinib Ditosylate

    CAS:
    <p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>
    Formula:C29H26ClFN4O4S·2C7H8O3S
    Purity:99.41%
    Color and Shape:Yellow Solid
    Molecular weight:925.46