Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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Silmitasertib sodium salt
CAS:<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Formula:C19H11ClN3NaO2Purity:99.49% - 99.62%Color and Shape:SolidMolecular weight:371.75Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Formula:C23H35NaO7Purity:97.14%Color and Shape:White Crystalline PowderMolecular weight:446.52NBDHEX
CAS:<p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>Formula:C12H15N3O4SPurity:97.38%Color and Shape:SolidMolecular weight:297.33Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Formula:C26H33FN4O7Purity:98% - 99.26%Color and Shape:SolidMolecular weight:532.56Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurity:97.16% - >99.99%Color and Shape:SolidMolecular weight:248.36Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formula:C47H51NO14Purity:98% - 99.92%Color and Shape:White PowderMolecular weight:853.91Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purity:99.06% - 99.67%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Formula:C26H30ClN3O6Purity:99.58% - 99.89%Color and Shape:Yellow SolidMolecular weight:515.99BIX 02565
CAS:<p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>Formula:C26H30N6O2Purity:97.44% - 99.7%Color and Shape:SolidMolecular weight:458.56Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formula:C8H14N2O4PtPurity:97% - 99.93%Color and Shape:SolidMolecular weight:397.29Colistin sulfate
CAS:<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Formula:C53H100N16O17SPurity:98%Color and Shape:PowderMolecular weight:1253.51Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14Lomustine
CAS:<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Formula:C9H16ClN3O2Purity:98.36% - 99.44%Color and Shape:Solid SolidMolecular weight:233.7Itraconazole
CAS:<p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>Formula:C35H38Cl2N8O4Purity:98% - 99.90%Color and Shape:Off-White Crystalline SolidMolecular weight:705.63Phenformin hydrochloride
CAS:<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formula:C10H16ClN5Purity:97.11% - 99.80%Color and Shape:Lactic AcidosisMolecular weight:241.72Memantine hydrochloride
CAS:<p>Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.</p>Formula:C12H22ClNPurity:99.56% - 99.96%Color and Shape:Crystalline SolidMolecular weight:215.76Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purity:98.22% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Formula:C27H29NO11·HClPurity:98% - 99.52%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formula:C24H25FNNaO4Purity:98.54% - 99.56%Color and Shape:Light Yellow Solid PowderMolecular weight:433.45Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formula:C27H30FN5O3Purity:98.82%Color and Shape:SolidMolecular weight:491.56Reserpine
CAS:<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formula:C33H40N2O9Purity:98.85% - 99.81%Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Molecular weight:608.68ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Formula:C23H28ClN7O3SPurity:98.32%Color and Shape:SolidMolecular weight:518.03Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formula:C6H12N2O4PtPurity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:371.25Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Formula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Formula:C28H28ClNO4SPurity:98% - 99.97%Color and Shape:Light Yellow SolidMolecular weight:510.044LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Formula:C23H26O3Purity:98.65%Color and Shape:SolidMolecular weight:350.45Pyrazinamide
CAS:<p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>Formula:C5H5N3OPurity:99.71% - 99.9%Color and Shape:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Molecular weight:123.11Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formula:C25H29I2NO3·HClPurity:99.82% - ≥95%Color and Shape:White To Cream Crystalline PowderMolecular weight:681.78Dexamethasone
CAS:<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Formula:C22H29FO5Purity:98% - 99.91%Color and Shape:Crystals From Ether (Ntp 1992)Molecular weight:392.46Avermectin B1
CAS:<p>Avermectin B1 is served as anthelmintic and insecticide.</p>Formula:C48H72O14Purity:mixture - mixtureColor and Shape:White PowderMolecular weight:873.09Mevastatin
CAS:<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formula:C23H34O5Purity:99.12%Color and Shape:White-Yellowish To Yellow Powder Solid PowderMolecular weight:390.51Cytarabine
CAS:<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formula:C9H13N3O5Purity:99.83% - 99.93%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:243.22Thalidomide
CAS:<p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>Formula:C13H10N2O4Purity:98.88% - 99.88%Color and Shape:White SolidMolecular weight:258.23Doxazosin mesylate
CAS:<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Formula:C24H29N5O8SPurity:99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:547.58Trimetazidine dihydrochloride
CAS:<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Formula:C14H24Cl2N2O3Purity:99.58%Color and Shape:Crystalline SolidMolecular weight:339.258Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Formula:C25H35N7O9S4Purity:99.63%Color and Shape:SolidMolecular weight:705.85Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05MLi-2
CAS:<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Formula:C21H25N5O2Purity:98.96%Color and Shape:SolidMolecular weight:379.46Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Dihydroartemisinin
CAS:<p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>Formula:C15H24O5Purity:98% - 99.41%Color and Shape:White SolidMolecular weight:284.35Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47Sophocarpine monohydrate
CAS:<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formula:C15H22N2OPurity:99.55%Color and Shape:SolidMolecular weight:246.35Dexamethasone acetate
CAS:<p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>Formula:C24H31FO6Purity:99.22% - 99.65%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:434.50Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formula:C24H40O4Purity:99.70% - 99.93%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57TTNPB
CAS:<p>TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),</p>Formula:C24H28O2Purity:99.55%Color and Shape:White SolidMolecular weight:348.48Naringin
CAS:<p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>Formula:C27H32O14Purity:99.23%Color and Shape:Beige Creamish Powder Solid Solid Particulate/PowderMolecular weight:580.53
