PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
- AMPK(170 products)
- ATM/ATR(72 products)
- DNA-PK(49 products)
- EGFR(572 products)
- MELK(7 products)
- PDK(9 products)
- PI3K(231 products)
- S6 Kinase(6 products)
- gsk-3(109 products)
- mTOR(163 products)
Show 2 more subcategories
Found 984 products of "PI3K/Akt/mTOR Signaling"
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Parsaclisib
CAS:Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)
Formula:C20H22ClFN6O2Purity:98.59%Color and Shape:SolidMolecular weight:432.88LCH-7749944
CAS:LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.Formula:C20H22N4O2Purity:99.48%Color and Shape:SolidMolecular weight:350.41Ref: TM-T11826
1mg50.00€5mg103.00€10mg156.00€25mg269.00€50mg403.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)110.00€Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.9Indazole
CAS:Indazole, a heterocyclic compound, offers diverse biological activities.Formula:C7H6N2Purity:99.59% - 99.85%Color and Shape:White Or Beige Crystalline PowderMolecular weight:118.14BRD0705
CAS:BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Formula:C20H23N3OPurity:99.01%Color and Shape:SolidMolecular weight:321.42Ref: TM-T10606
1mg94.00€5mg173.00€10mg253.00€25mg374.00€50mg525.00€100mg702.00€1mL*10mM (DMSO)190.00€Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purity:99.4% - 99.95%Color and Shape:Colorless Crystals From Ethanol + Ether White Crystalline PowderMolecular weight:512.33NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.68Ref: TM-T16355
2mg39.00€5mg60.00€10mg87.00€25mg159.00€50mg231.00€100mg355.00€200mg505.00€1mL*10mM (DMSO)84.00€Petosemtamab
CAS:Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.
Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.97 kDaTenalisib
CAS:Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)Formula:C23H18FN5O2Purity:99.71%Color and Shape:SolidMolecular weight:415.42Ref: TM-T13119
1mg35.00€2mg50.00€5mg77.00€10mg105.00€25mg178.00€50mg289.00€100mg434.00€1mL*10mM (DMSO)84.00€AV-412
CAS:AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).Formula:C41H44ClFN6O7S2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:851.41Ref: TM-T10419
1mg42.00€2mg55.00€5mg90.00€10mg137.00€25mg240.00€50mg403.00€100mg582.00€1mL*10mM (DMSO)129.00€LTURM34
CAS:LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.Formula:C24H18N2O3SPurity:99.34%Color and Shape:SolidMolecular weight:414.48Ref: TM-T15789
5mg43.00€10mg71.00€25mg138.00€50mg231.00€100mg344.00€200mg505.00€1mL*10mM (DMSO)47.00€Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Gefitinib
CAS:Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.Formula:C22H24ClFN4O3Purity:99.92% - >99.99%Color and Shape:Light-Yellow Crystalline PowderMolecular weight:446.90Allitinib
CAS:Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]Formula:C24H18ClFN4O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:448.88Ref: TM-T14336
1mg50.00€5mg105.00€10mg172.00€25mg313.00€50mg467.00€100mg663.00€1mL*10mM (DMSO)128.00€Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47O-Desmethyl gefitinib
CAS:O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.Formula:C21H22ClFN4O3Purity:97.17%Color and Shape:SolidMolecular weight:432.88Ref: TM-T16369
1mg52.00€5mg105.00€10mg167.00€25mg324.00€50mg518.00€100mg742.00€1mL*10mM (DMSO)114.00€MELK-IN-1
CAS:MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).Formula:C31H33N5O4Purity:99.84%Color and Shape:SolidMolecular weight:539.62Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.469-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purity:99.32%Color and Shape:SolidMolecular weight:404.35Ref: TM-T14066
1mg50.00€2mg66.00€5mg94.00€10mg155.00€25mg309.00€50mg447.00€100mg667.00€1mL*10mM (DMSO)110.00€SAR405 R enantiomer
CAS:SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.Formula:C19H21ClF3N5O2Purity:98.04%Color and Shape:SolidMolecular weight:443.85Ref: TM-T12831
1mg46.00€5mg96.00€10mg149.00€25mg248.00€50mg359.00€100mg502.00€200mg683.00€1mL*10mM (DMSO)94.00€
