Alcohols

(1R,4aS,7S,7aR)-Hexahydro-4,7-dimethylcyclopenta[c]pyran-1-ol is a chemical compound that belongs to the group of speciality chemicals. It is an intermediate for a number of different reactions in the synthesis of complex molecules and can be used as a building block for new compounds. This compound has a number of industrial applications and can be used in research as well as in the production of pharmaceuticals. The CAS number for this compound is 109215-55-6.

Clioquinol is a topical corticosteroid that is used to treat skin disorders such as pemphigoid, psoriasis, and eczema. It is also used to treat the inflammation associated with acne. Clioquinol has been shown to be effective in treating bacterial infections of the skin by inhibiting the growth of bacteria. This drug also has anti-inflammatory properties and can be used for the treatment of various inflammatory skin conditions. Clioquinol is not absorbed through the skin and does not affect the blood's ability to clot.

Androstenediol-3-acetate-17-benzoate is a chemical building block that has been used in the synthesis of various pharmaceuticals and other organic compounds. It is a versatile intermediate for the synthesis of complex natural products such as corticosteroids, sex hormone analogs, and other drugs. Androstenediol-3-acetate-17-benzoate has also been found to be an effective treatment for bronchitis.

2-Chloro-6-nitrobenzyl alcohol is a versatile building block that is used as a reactant in chemical synthesis. It is used to synthesize other compounds, such as pharmaceuticals and pesticides. This compound can also be used as an intermediate or scaffold in the synthesis of more complex compounds. 2-Chloro-6-nitrobenzyl alcohol has been shown to have a high quality and is useful for research purposes. It can be used in the production of fine chemicals, useful building blocks, and reagents.

5-Hexen-2-ol is a constituent of various natural products such as the racemosum and macrocyclic lactones. It has been found to have a broad spectrum of biological activities, including antibacterial, antifungal, antiparasitic and antimalarial activity. 5-Hexen-2-ol has also been used in the synthesis of various macrocyclic lactones and macrolactones. This compound has been found to inhibit penicillium growth by competitive inhibition of ergosterol biosynthesis.

Octacosanol is a mixture of eight fatty alcohols that can be found in wheat germ oil. It has been shown to have hypoglycemic effects and may be useful for the treatment of bowel disease. Octacosanol has been shown to have anti-inflammatory properties, which may be due to its ability to prevent the release of prostaglandin E2 from macrophages, thereby inhibiting the production of inflammatory mediators. It also binds to 2-adrenergic receptors and is thought to regulate energy metabolism by increasing levels of ATP in cells. Octacosanol is commonly used for elderly patients with metabolic disorders such as type II diabetes or hyperlipidemia.

2,2,2-tribromoethanol or TBE derives from ethanol, where the hydrogen atoms from one carbon are substituted by bromine. 2,2,2-tribromoethanol is frequently used as initiator for synthesising functionalised polymers with end hydroxyl groups. In addition, 2,2,2-tribromoethanol is also often used in a labroatory setting to anaethetise mice.

1-Benzylglycerol is a bifunctional reagent that can be used as an inorganic base or an organic solvent. It has been used to synthesize enantiopure compounds, such as fatty acids. 1-Benzylglycerol reacts with boron trifluoride etherate to form the corresponding ester, which is a reaction system for the synthesis of persulfates. The hydroxyl group on 1-benzylglycerol can be reacted with hydroxyl groups on fatty acids, catalyzed by lipase or chemoenzymes, to produce esters. 1-Benzylglycerol has been used in asymmetric synthesis and carbon tetrachloride immobilization reactions.

(R)-(+)-3-Benzyloxy-1,2-propanediol is a biologically active compound. It has been shown to have the ability to inhibit tumor growth and enhance the activity of certain anticancer drugs. (R)-(+)-3-Benzyloxy-1,2-propanediol is an enantiomer that has been found to be more potent than its counterpart. The biological function of (R)-(+)-3-Benzyloxy-1,2-propanediol is not entirely clear, but it may be involved in the metabolism of fatty acids and fatty acid esters. This compound can also increase levels of ATP in cells.

Trans-1,2-cyclohexanediol is a chemical compound that has been shown to have infectivity in the treatment of cardiac disorders. It has also been shown to be an effective anti-inflammatory agent and may have clinical relevance in the treatment of congestive heart disease. The mechanism of action is unknown, but it may be due to its ability to inhibit the production of prostaglandin E2 and thromboxane A2 by inhibiting cyclooxygenase. Trans-1,2-cyclohexanediol has also been shown to be metabolized into glucuronide conjugates, which are excreted through the kidneys.

3-Aminobutan-1-ol is an amine that is synthesized industrially by the reduction of soybean trypsin with borohydride. This chemical has been used as a substrate in asymmetric synthesis and can be detected by high detection sensitivity. 3-Aminobutan-1-ol binds to the carbonyl group of amino acid residues and causes a reaction with chloride ions for detection. The product of this reaction is an enantiomer, which can be separated from other reaction products by purified chiral stationary phases. 3-Aminobutan-1-ol is also involved in the biosynthesis of proteins and enzymes. It reacts with hydrochloric acid to form a salt, which can then be used as an enzyme inhibitor.

4,4-Dimethyl-1-[(3,4-methylenedioxy)phenyl]-1-penten-3-ol is a drug that has been used in the treatment of Dravet syndrome. This drug is also known as 3,4-methylenedioxyphenylacetone. It is a competitive inhibitor of the enzyme citrate synthase and inhibits the conversion of acetate to citrate. The effect of 4,4-dimethyl-1-[(3,4-methylenedioxy)phenyl]-1-penten-3-ol on sodium citrate concentrations is concentration dependent and results in an increase in plasma sodium concentrations with prolonged administration. Other drugs that are metabolized by the cytochrome P450 system may interact with 4,4-dimethyl-1-[(3,4 methylenedioxy)phenyl]-1 penten 3 ol and lead to increased levels of these drugs in the blood.

(3,4,5-Trimethoxyphenyl)methyl carbinol is a neuroprotective compound that belongs to the class of benzyl alcohols. It has been shown to have neuroprotective effects against daldinia-induced oxidative stress and biotoxicity. This compound has high electron transfer rates and can be used as an electron donor in enzymatic reactions. (3,4,5-Trimethoxyphenyl)methyl carbinol exhibits a high reactivity with alcohols and can be used in the synthesis of other compounds by transferring its alcohol group onto other molecules. The addition of deuterium atoms to this molecule has been shown to increase its reactivity with oxidants.

Applications 1,4-Cyclohexanediol is used as a reagent in the development of noviomimetics as C-terminal Hsp90 inhibitors.
References Anyika, M., et al.: ACS Med. Chem. Lett., 7, 67 (2016)

Applications 1-Butanol is a common chemical reagent used in biodiesel production. Also it has been used in the study the polarization of vapor-deposited 1-butanol films (1) as well as in the preparation of bioavailable CB1 antagonists (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Gavra, I. et al.: J. Chem. Phys. 2017 Mar 14;146(10):104701.2. Röver, S. et al.: J. Med. Chem. 2013 Dec 27;56(24):9874-96.

Applications 1-Ethynylcyclohexanol is used in the preparation of 9-methyladenines used as adenosine receptor antagonists. Also used in the cycloadition of alkynes to organic azides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harada, H. et al.: J. Med. Chem. 44, 170 (2001); Zhang, L. et al.: J. Am. Chem. Soc., 127, 15998 (2005);

Applications A substituted alkynyl phenoxy compound as new synergists in pesticidal compositions.
References Hefner,T., et al.: Bioorg. Med. Chem., 10, 1731 (2002),

Stability -20°C Freezer
Applications Useful reagent for preparing amino acid pentachlorophenol active esters.
References Kovacs, J., et al.: J. Am. Chem. Soc., 89, 183 (1967)

Applications 1-(Benzyloxy)-3-[[bis(benzyloxy)phosphoryl]oxy]propan-2-ol is an intermediate in the synthesis of Dihydroxyacetone Phosphate Lithium Salt (D450538), which is a metabolic intermediate involved in involved in a wide variety of metabolic pathways including glycolysis and lipid biosynthesis. In plants, Dihydroxyacetone phosphate is involved with the synthesis of vitamin B6.
References Jun Ogawa et. al.: et al.: Bioscience, biotechnology, and biochemistry, 67(4), undefined (2003-6-6); John P Richard, Biochemistry, 51(13), undefined (2012-3-14);

Applications 1,2-Butanediol is a glycol in human serum.
References Imbert, L., et al.: J. Anal. Toxicol., 38, 676 (2014)

Applications N-Benzylethanolamine is used in the synthesis of imidazoles as potent calcitonin (CGRP) antagonists. Also it aids in the preparation of benzofused hydroxamix acids, as useful fragments for the synthesis of histone deacetylase inhibitors.
References Tora, G. et al.: Bioorg. Med. Chem. Lett., 23, 5684 (2013); Marastoni, E. et al.: Bioorg. Med. Chem. Lett., 23, 4091 (2013);

Applications 2-(4-Octylphenyl)ethanol (cas# 162358-05-6) is a compound useful in organic synthesis.

Applications 2-Phenyl-4-nitrosophenol is an intermediate in the synthesis of (E)-2-((6-Hydroxy-[1,1'-biphenyl]-3-yl)((6-hydroxy-[1,1'-biphenyl]-3-yl)imino)methyl)benzoic Acid which is an impurity of (S)-Cloperastine (C587195); a drug used in the treatment of chronic non-productive cough. Also antitussive.
References Aliprandi, P. et al.: Drugs Exp. Clin. Res., 30, 133 (2004); Aliprandi, P. et al.: Clin. Drug Invest. 22, 209 (2002)

Applications 2,4,4-Trimethyl-2-pentanol is an intermediate formed from incubation of Sphingomonas sp. strain with xeno-estrogenic octylphenol. It was used in study comparing the relative binding affinities of low-molecular-weight proteins from humans versus male rats.
References Tanghe, Tom., et al.: Biodegradation, 11, 11 (2000); Borghoff, S., et al.: Toxicol. Appl. Pharm., 119, 228 (1993);

Applications 3-(2-Pentyl)phenol is an intermediate in the synthesis of Bufencarb (B689385), a carbamate pesticide used mainly as an insecticide.
References Nesterova, T.N., et al.: J. Chem. Thermodyn., 21, 385 (1989);

Applications 1,3-Bis(tert-Butyldimethylsiloxy)-2-propanol is an intermediate in the synthesis of 2-Linoleoyl-rac-glycerol (L467960), which is a atty acid monoglycerides in vegetable oils with medium unsaturation.
References Compton, D., et al.: J. Pharmacol. Exp. Ther., 277, 586 (1996), Devane, W., et al.: Science, 258, 1946 (1992),

Applications (S)-2-(Benzylamino)propan-1-ol is a useful research chemical for the preparation of cross-benzoin products of heteroaromatic aldehydes and amino aldehydes.
References Haghshenas, P., et al.: J. Org. Chem., 81, 12075-83 (2016);

Applications 1-(Phenylmethoxy)-3-(2-propen-1-yloxy)-2-propanol (cas# 83016-75-5) is a compound useful in organic synthesis.