
Inhibitors
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,901 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,153 products)
- Metabolism(10,140 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,405 products)
- Other Inhibitors(35,850 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Found 66518 products of "Inhibitors"
Strictamine
CAS:Strictamine is a akuammiline alkaloid.Formula:C20H22N2O2Color and Shape:SolidMolecular weight:322.41Mycalolide B
CAS:Mycalolide-B, from marine sponges, blocks actomyosin ATPase, stopping ATP-triggered contraction without Ca2+.
Formula:C52H74N4O17Color and Shape:SolidMolecular weight:1027.175TLR7/8 agonist 4 hydroxy-PEG10-acid
CAS:TLR7/8 agonist 4-PEG10-acid (compound 9) is a potent ADC linker for cancer therapy with a cleavable bond.
Formula:C41H68N6O12Color and Shape:SolidMolecular weight:837.025Denileukin diftitox
CAS:Denileukin diftitox is a diphtheria/IL-2 fusion toxin targeting cells with high-affinity IL-2 receptors.Color and Shape:SolidDehydroaustinol
CAS:Dehydroaustinol is a natural product that can be used as a reference standard. The CAS number of Dehydroaustinol is 82893-33-2.Formula:C25H28O8Color and Shape:SolidMolecular weight:456.4912α-Methyl androsterone
CAS:2α-Methyl androsterone, a metabolite of mesterolone and drostanolone, is classified as an anabolic androgenic steroid.Formula:C20H32O2Color and Shape:SolidMolecular weight:304.47D-Erythritol 4-phosphate
CAS:D-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate.Formula:C4H11O7PColor and Shape:SolidMolecular weight:202.10N-cis-octadec-9Z-enoyl-L-Homoserine lactone
CAS:Quorum sensing involves bacteria using AHLs to coordinate gene expression for biofilm formation and virulence, via LuxR regulators.Formula:C22H39NO3Color and Shape:SolidMolecular weight:365.558cis-Tadalafil
CAS:Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.
Formula:C22H19N3O4Purity:99.89%Color and Shape:SolidMolecular weight:389.42-Methylquinazolin-4-ol
CAS:Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.Formula:C9H8N2OPurity:99.98%Color and Shape:SolidMolecular weight:160.17Clindamycin Sulfoxide
CAS:Clindamycin sulfoxide, an active clindamycin metabolite formed by CYP3A4, inhibits P. prevotti, B. fragilis, C. sordelli with MICs 2, 2, 1 mg/L.Formula:C18H33ClN2O6SColor and Shape:SolidMolecular weight:440.98Tribromonitromethane
CAS:Tribromonitromethane is a member of the class of Halonitromethanes, a newly identified group of disinfection by-products (DBPs) found in drinking water.
Formula:CBr3NO2Color and Shape:SolidMolecular weight:297.728Saflufenacil
CAS:Saflufenacil is a uracil-based herbicide used to control annual broadleaf weeds in soybeans and corn.Formula:C17H17ClF4N4O5SPurity:98.12%Color and Shape:SolidMolecular weight:500.85Aceclofenac methyl ester
CAS:Aceclofenac methyl ester belongs to the aryl propionic acid derivativesFormula:C17H15Cl2NO4Color and Shape:SolidMolecular weight:368.214-N-Nonyloxyphenol
CAS:4-N-Nonyloxyphenol, kaolinite nanotube photosensitizer, degrades phenolic pesticides, and disrupts endocrine.
Formula:C15H24O2Purity:99.94%Color and Shape:SoildMolecular weight:236.357-Acetyllycopsamine
CAS:Lycopsamine `1-acetate is a bioactive chemical.
Formula:C17H27NO6Color and Shape:SolidMolecular weight:341.4Sintamil
CAS:Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.Formula:C18H20ClN3O4Color and Shape:SolidMolecular weight:377.82Tylophorine
CAS:Tylophorine, from Tylophora indica, has anti-inflammatory, antitumor effects, halts G1 phase in cancer cells by suppressing cyclin A2.Formula:C24H27NO4Color and Shape:SolidMolecular weight:393.48Nornidulin
CAS:Nornidulin, a depsidone from A. nidulans, fights various bacteria, fungi, MRSA (MIC=2 μg/ml), and has larvicidal (LC50=1.7 μg/ml) and cytotoxic properties.Formula:C19H15Cl3O5Color and Shape:SolidMolecular weight:429.6716-Deacetyloleandrin
CAS:16-Deacetyloleandrin is a biochemical.Formula:C30H46O8Color and Shape:SolidMolecular weight:534.69THK01
CAS:THK01: ROCK2 inhibitor (IC50=5.7nM), less effective on ROCK1 (923nM). Hinders breast cancer spread via ROCK2-STAT3. For cancer research.Formula:C20H13N3O2Color and Shape:SolidMolecular weight:327.34(-)-Benzotetramisole
CAS:(-)-Benzotetramisole, a benzannulated tetraimidazole derivative, serves as an efficient, selective catalyst for conversions.Formula:C15H12N2SPurity:98.7%Color and Shape:SolidMolecular weight:252.33Isochromophilone VI
CAS:Isochromophilone VI is a natural product that can be used as a reference standard. The CAS number of Isochromophilone VI is 167173-91-3.Formula:C23H28ClNO5Color and Shape:SolidMolecular weight:433.93MC-VC-PAB-MMAD
MC-VC-PAB-MMAD: potent antitumor ADC w/ cleavable linker & MMAD, a tubulin inhibitor.
Formula:C71H105N11O14SColor and Shape:SolidMolecular weight:1368.72Viquidacin
CAS:NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.Formula:C25H29FN2O4S2Color and Shape:SolidMolecular weight:504.64ALK-IN-13
CAS:ALK-IN-13 is an ALK inhibitor.
Formula:C29H39ClN7O2PColor and Shape:SolidMolecular weight:584.1Formylmethanofuran
CAS:Formylmethanofuran is regarded as intermediate in the reduction of CO2 to methane.Formula:C35H44N4O16Color and Shape:SolidMolecular weight:776.749Melarsomine
CAS:Melarsomine is a trivalent arsenic drug used to treat canine heartworm and other worms. It's key in related research.Formula:C13H21AsN8S2Color and Shape:SolidMolecular weight:428.41PCSK9 degrader 1
CAS:PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function.
Formula:C34H34FN3O6SColor and Shape:SolidMolecular weight:631.71Alphitonin
CAS:Alphitonin: a flavonoid in L. leptolepis wood, metabolized from quercetin by E. ramulus in the gut.
Formula:C15H12O7Color and Shape:SolidMolecular weight:304.25Propargyl-PEG1-THP
CAS:Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.
Formula:C10H16O3Color and Shape:SolidMolecular weight:184.235CAY10606
CAS:CAY10606 has a wide range of applications in life science related research.
Formula:C22H18ClNO3Color and Shape:SolidMolecular weight:379.84Neoaureothin
CAS:Neoaureothin, a Streptomyces metabolite, is an AR antagonist with anti-androgen and cytotoxic effects, also active against B. xylophilus.
Formula:C28H31NO6Color and Shape:SolidMolecular weight:477.557Dehydrozingerone
CAS:Dehydrozingerone, a natural versatile compound, is known for diverse biochemical effects.Formula:C11H12O3Purity:99.89%Color and Shape:SolidMolecular weight:192.21Thyminalkamine
CAS:Thyminalkamine is a biochemical.
Formula:C9H14Cl3N3O2Color and Shape:SolidMolecular weight:302.58N-Acetyl-α-D-glucosamine 1-phosphate disodium
CAS:N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linkedFormula:C8H15NNaO9PColor and Shape:SolidMolecular weight:323.17Suicin 65
Suicin 65, a class I type B lantibiotic synthesized by Streptococcus suis, exhibits activity against all S. suis isolates [1].Color and Shape:Odour SolidABzOH
CAS:2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.
Formula:C12H10O2Purity:99.43%Color and Shape:SolidMolecular weight:186.21IL-17 modulator 3
CAS:IL-17 modulator 3 targets IL-17, with potential for inflammation, cancer, autoimmune study.Formula:C31H45N7O4Color and Shape:SolidMolecular weight:579.746Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColor and Shape:SolidMolecular weight:672.39IDO1-IN-7
CAS:IDO1-IN-7 is a potent IDO1 inhibitor with a 6.1 nM IC50 and immunomodulatory effects for cancer research.Formula:C22H19ClFN3O3Color and Shape:SolidMolecular weight:427.86Neamine
CAS:Neamine: antibiotic, anti-angiogenic, battles bacteria, cancer, protects nerves.Formula:C12H26N4O6Color and Shape:SolidMolecular weight:322.36Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine
CAS:Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine: an ISAC with anti-HER2, STING agonist ADU-S100, linker; for cancer research.Formula:C51H65N17O19P2S2·xC6H15NColor and Shape:SolidMolecular weight:1447.44Gemtuzumab
CAS:Gemtuzumab, a humanized IgG4 monoclonal antibody, targets CD33 antigen; used to create ADC for acute myeloid leukemia research.Purity:SDS-PAGE:98.4%;SEC-HPLC:95.5%Color and Shape:LiquidMolecular weight:145.2 kDaJAMI1001A
CAS:JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.Formula:C16H17F3N4O3SColor and Shape:SolidMolecular weight:402.39T-91825
CAS:T-91825 (PPI-0903M), an active N-phosphono cephalosporin, is potent against various bacteria and stems from TAK-599.Formula:C22H20N8O5S4Color and Shape:SolidMolecular weight:604.69CCG258208 hydrochloride
GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) & GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.
Color and Shape:Solid2-Amino-6-bromopyridine
CAS:2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.Formula:C5H5BrN2Purity:99.98%Color and Shape:SolidMolecular weight:173.01CAY10591
CAS:SIRT1 activated by CAY10591, mimics caloric restriction, extends lifespan, inhibits apoptosis, suppresses TNF-α, and promotes fat mobilization.
Formula:C20H25N5O2Color and Shape:SolidMolecular weight:367.44Commendamide
CAS:Commendamide, natural, mimics N-acyl-amides, activates GPR132 with EC50 of 11.8 μM, made by Cbeg12 gene in commensal bacteria.Formula:C18H35NO4Color and Shape:SolidMolecular weight:329.47Paspaline
CAS:Paspaline is an indole-diterpene.Formula:C28H39NO2Color and Shape:SolidMolecular weight:421.617-MAD-MDCPT
CAS:7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).Formula:C22H19N3O6Color and Shape:SolidMolecular weight:421.409Helenalin tiglate
CAS:Helenalin tiglate is a useful organic compound for research related to life sciences. The catalog number is T123976 and the CAS number is 89708-26-9.Formula:C20H24O5Color and Shape:SolidMolecular weight:344.4071,3,6-Trihydroxy-2,5-dimethoxyxanthone
1,3,6-Trihydroxy-2,5-dimethoxyxanthone is a useful organic compound for research related to life sciences and the catalog number is T124992.Formula:C30H22O14Color and Shape:SolidMolecular weight:606.492Glutamylputrescine
CAS:Glutamylputrescine catalyzes the gamma-glutamylation of putrescine.Formula:C9H19N3O3Color and Shape:SolidMolecular weight:217.27Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Formula:C21H32BrNO2Color and Shape:SolidMolecular weight:410.39UCM 549
CAS:UCM 549 is a bioactive chemical.Formula:C19H21NO2Color and Shape:SolidMolecular weight:295.3817(R)-HETE
CAS:Kidney sodium transport is partly controlled by 17-HETE, a CYP450 metabolite of arachidonic acid, with the (S) enantiomer inhibiting ATPase at 2 μM.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473Bengamide B
CAS:Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.Formula:C32H58N2O8Color and Shape:SolidMolecular weight:598.81D-threo-PPMP
CAS:D-threo-PPMP, a powerful glucosylceramide (GlcCer) synthase inhibitor, effectively impedes karyokinesis and decreases cyst formation.
Formula:C29H50N2O3Color and Shape:SolidMolecular weight:474.73Resveratrol-3-O-sulfate sodium
CAS:Resveratrol-3-O-sulfate reduces IL-1α/β, IL-6, TNF-α in LPS-stimulated U-937 cells, inhibits Caco-2 cell growth, induces apoptosis, and binds mitoNEET.Formula:C14H11NaO6SColor and Shape:SolidMolecular weight:330.29Ajacusine
CAS:Ajacusine is a biochemical.Formula:C43H52N2O11Color and Shape:SolidMolecular weight:772.88Eritoran
CAS:Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.Formula:C66H126N2O19P2Color and Shape:SolidMolecular weight:1313.66Triisocetyl citrate
CAS:Triisocetyl citrate is a bioactive chemical.Formula:C54H104O7Color and Shape:SolidMolecular weight:865.4Cefmetazole
CAS:Cefmetazole is a second-generation semi-synthetic β-lactam cephalosporin antibiotic with antimicrobial activity.Formula:C15H17N7O5S3Color and Shape:SolidMolecular weight:471.5328-Deoxybetulin methyleneamine
CAS:28-Deoxybetulin methyleneamine, a triterpenoid derived from betulin, aids in creating antiviral triterpene compounds.Formula:C31H53NOColor and Shape:SolidMolecular weight:455.771(±)10(11)-EpDPA
CAS:Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495Terchebulin
CAS:Terchebulin is a useful organic compound for research related to life sciences. The catalog number is T126044 and the CAS number is 132854-40-1.Formula:C48H28O30Color and Shape:SoildMolecular weight:1084.722GSK040
CAS:GSK040: Potent BET BD2 inhibitor, pIC50 8.3, 5000x selectivity over BD1, for oncology & immunology research.Formula:C29H34N4O4Color and Shape:SolidMolecular weight:502.6Thailanstatin D
CAS:Thailanstatin D blocks AR-V7 splicing, disrupts U2AF65/SAP155 binding, and induces apoptosis in CRPC xenografts.
Formula:C28H41NO8Color and Shape:SolidMolecular weight:519.635Setidegrasib
CAS:KRAS G12D inhibitor 17, a quinazoline-linked prolinamide, degrades mutant KRAS protein; a PROTAC.Formula:C60H65FN12O7SColor and Shape:SolidMolecular weight:1117.3Isariin D
CAS:Isariin D is a new cyclodepsipeptide.
Formula:C26H45N5O7Color and Shape:SolidMolecular weight:539.66Trifluoperazine N-Glucuronide
CAS:Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity.Formula:C27H32F3N3O6SColor and Shape:SolidMolecular weight:583.62Adrenocorticotropic hormone
CAS:ACTH, a polypeptide, is secreted by the pituitary gland and regulates cortisol and androgen.Color and Shape:SolidPyrenophorol
CAS:Pyrenophorol is a useful organic compound for research related to life sciences. The catalog number is T125304 and the CAS number is 22248-41-5.Formula:C16H24O6Color and Shape:SolidMolecular weight:312.362Prazobind
CAS:Prazobind is a prazosinoid substance that blocks insulin stimulation of IP1 (inositol phosphate) accumulation and is an effective α1 adrenoceptor blocker.Formula:C23H27N5O3Color and Shape:SolidMolecular weight:421.501Rachelmycin
CAS:Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Formula:C37H33N7O8Color and Shape:SolidMolecular weight:703.712D,L-erythro-PDMP
CAS:D,L-erythro-PDMP inhibits growth in rabbit fibroblasts and blocks UDP-glucose: ceramide glucosyltransferase.Formula:C23H38N2O3Color and Shape:SolidMolecular weight:390.568LAS190792
CAS:LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.Formula:C39H43ClN4O9S2Color and Shape:SolidMolecular weight:811.36BMS-753426
CAS:BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
Formula:C25H33F3N6O2Color and Shape:SolidMolecular weight:506.57417-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
CAS:A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the onesFormula:C24H33F3O5Color and Shape:SolidMolecular weight:458.518Fmoc-Phe-Lys(Trt)-PAB
CAS:Fmoc-Phe-Lys(Trt)-PAB is a cleavable linker for antibody-drug conjugates (ADCs) synthesis.
Formula:C56H54N4O5Color and Shape:SolidMolecular weight:863.071Setosusin
CAS:Setosusin, a meroterpenoid from C. setosus, reduces Aβ-induced neurotoxicity in PC12 cells (EC50 = 112.6 μM).Formula:C29H38O8Color and Shape:SolidMolecular weight:514.615ODN 2395
CAS:ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].
Color and Shape:SolidMolecular weight:7035Dracorhodin
CAS:Dracorhodin, from sanguis draconis, is a flavylium-type anthocyanin that causes vasodilation.Formula:C17H14O3Color and Shape:SolidMolecular weight:266.296DOSPA
CAS:DOSPA, a cationic lipid, exhibits significant potential when formulated with DNA as a transfection system [1].Formula:C54H115Cl5N6O3Color and Shape:SolidMolecular weight:1073.79Anhydroepiophiobolin A
CAS:Anhydroepiophiobolin A, a sesterterpenoid from B. oryzae, is cytotoxic to various cancer cells and phytotoxic in leaf assays.
Formula:C25H34O3Color and Shape:SolidMolecular weight:382.544TRPA1-IN-1
CAS:TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.Formula:C19H17ClN6O3Color and Shape:SolidMolecular weight:412.83Tolypomycin Y
CAS:Tolypomycin Y is a naturally occurring ansamycin antibiotic.
Formula:C43H54N2O14Purity:98%Color and Shape:SolidMolecular weight:822.905Camellianin B
CAS:Camellianin B, a flavonoid from Camellianin A, has antioxidant effects and blocks ACE.Formula:C27H30O14Color and Shape:SolidMolecular weight:578.523MC-betaglucuronide-MMAE-1
CAS:MC-betaglucuronide-MMAE-1: ADC drug-linker with MMAE, inhibits tubulin polymerization, has potent antitumor effects.Formula:C66H98N8O20Color and Shape:SolidMolecular weight:1323.546Fuscin
CAS:Fuscin, a quinonoid from O. fuscum, inhibits ADP/ATP translocase, depletes glutathione, disrupts NADH oxidation, and blocks MIP-1α/CCR5 binding (IC50: 21µM).Formula:C15H16O5Color and Shape:SolidMolecular weight:276.288Hydroxydehydro Nifedipine Carboxylate
CAS:Hydroxydehydro nifedipine carboxylate is a metabolite of nifedipine .1Formula:C16H14N2O7Color and Shape:SolidMolecular weight:346.295Propargyl-C8-amido-PEG2-NHS ester
CAS:Propargyl-C8-amido-PEG2-NHS ester: a non-cleavable linker for antibody-drug synthesis, enabling targeted drug delivery.
Formula:C22H34N2O7Color and Shape:SolidMolecular weight:438.51MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
CAS:MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan: ADC's agent-linker, with DNA topoisomerase I inhibitor Exatecan (IC50=2.2 μM).Formula:C55H60FN9O13Color and Shape:SolidMolecular weight:1074.124-oxo-2-Nonenal
CAS:4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.
Formula:C9H14O2Color and Shape:SolidMolecular weight:154.209Quinelorane
CAS:Quinelorane is dextrorotary isomer.Formula:C14H22N4Color and Shape:SolidMolecular weight:246.35COG 133 TFA
CAS:COG 133 TFA: APOE peptide fragment; binds LDL receptor; anti-inflammatory; neuroprotective; nAChR antagonist; IC 50 445 nM.
Formula:C99H182F3N37O21Color and Shape:SolidMolecular weight:2283.78Desacetylcephapirin sodium
CAS:Desacetyl cefapirin, a cefapirin metabolite, combats E. coli, K. pneumoniae, P. mirabilis, S. aureus; MICs: 120, 24, 34, 0.42 μg/ml.Formula:C15H15N3NaO5S2Color and Shape:SolidMolecular weight:404.41

