Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,687 products)
- Apoptosis(6,097 products)
- Cell Cycle/Checkpoint(4,691 products)
- Chromatin/Epigenetics(2,376 products)
- Cytoskeletal Signaling(1,472 products)
- DNA Damage/DNA Repair(2,921 products)
- Endocrinology/Hormones(3,611 products)
- Enzyme(3,655 products)
- GPCR/G-Protein(8,755 products)
- Immunology and Inflammation(3,765 products)
- Influenza Virus(298 products)
- JAK/STAT signaling(407 products)
- MAPK Signaling(1,230 products)
- Membrane Transporter/Ion Channel(2,947 products)
- Metabolism(9,940 products)
- Microbiology/Virology(7,347 products)
- Neuroscience(10,240 products)
- Other Inhibitors(36,533 products)
- Oxidation-Reduction(43 products)
- PI3K/Akt/mTOR Signaling(1,437 products)
- Proteases/Proteasome(1,675 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,028 products)
- Ubiquitination(1,682 products)
Show 16 more subcategories
Found 66582 products of "Inhibitors"
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Afizagabar
CAS:<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Formula:C19H12FN3O2SColor and Shape:SolidMolecular weight:365.38Anticancer agent 103
CAS:Compound 103 (Compound 2k) serves as a potent anticancer agent [1].Formula:C18H20BrN3OColor and Shape:SolidMolecular weight:374.28RCB16007
CAS:<p>RCB16007 is a Yellow Fever Virus (YFV) inhibitor that also demonstrates inhibitory action against the West Nile virus with an effective concentration (EC50) of</p>Formula:C18H14ClN5O2SColor and Shape:SolidMolecular weight:399.85Inz-1
CAS:Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Formula:C16H14N2O2Purity:99.55% - 99.88%Color and Shape:SolidMolecular weight:266.29Itch-Targeting Compound 1
CAS:Compound 1: Anti-itch, combats bites, allergens, infections, vermination, dialysis-related itching.Formula:C25H36ClN3O3Purity:98%Color and Shape:SolidMolecular weight:462.03GGFG-Eribulin
CAS:<p>Eribulin-GGFG (Compound GGFG) is a drug-linker conjugate for antibody-drug conjugates (ADCs).</p>Formula:C55H77N5O15Color and Shape:SolidMolecular weight:1048.22TASP0412098
CAS:TASP0412098 is a potent, selective CRTH2 antagonist with oral activity.Formula:C27H23ClN2O3Purity:98%Color and Shape:SolidMolecular weight:458.94hDHODH-IN-1
CAS:hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Formula:C17H14N2O2Purity:99.97%Color and Shape:SolidMolecular weight:278.31GLL398
CAS:<p>GLL398: Oral ERα down-regulator, binds strongly (IC50=1.14nM), degrades ERα in MCF-7 cells (IC50=0.21μM).</p>Formula:C25H23BO4Color and Shape:SolidMolecular weight:398.26EPI-7170
CAS:EPI-7170: Ralaniten analogue, blocks androgen receptor, inhibits transcription in AR & variants, fights enzalutamide-resistant prostate cancer.Formula:C22H28Cl3NO6SColor and Shape:SolidMolecular weight:540.88Antiproliferative agent-18
CAS:Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].Formula:C26H27FN2OSColor and Shape:SolidMolecular weight:434.57Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan
CAS:Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising Exatecan tethered by a maleimidopropyl (Mal)Formula:C57H65FN10O15Color and Shape:SolidMolecular weight:1149.18Kv3 modulator 4
CAS:Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.Formula:C20H24N2O4Purity:98%Color and Shape:SolidMolecular weight:356.42Piprofurol
CAS:Piprofurol is used as a Calcium channel blocker.Formula:C26H33NO6Purity:98%Color and Shape:SolidMolecular weight:455.54GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Formula:C20H25N5O4SColor and Shape:SolidMolecular weight:431.51mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Formula:C19H22N2O2Color and Shape:SolidMolecular weight:310.392-Ethynyl Adenosine
CAS:2-Ethynyl Adenosine, Adenosine derivative, tracks novel polyadenylated transcription, non-radioactive AMPylation reporter.Formula:C12H13N5O4Color and Shape:SolidMolecular weight:291.26ND-378
CAS:ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.Formula:C18H19NO4S2Purity:98%Color and Shape:SolidMolecular weight:377.48DA-3934
CAS:DA-3934 targets gastrin/CCK-B receptors, not CCK-A, and reduces rat gastric acid secretion dose-dependently.Formula:C35H35N5O7Purity:98%Color and Shape:SolidMolecular weight:637.68Mesendogen
CAS:Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Formula:C18H16ClF3N2OSPurity:99.66%Color and Shape:SolidMolecular weight:400.85hCAIX-IN-16
CAS:hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formula:C20H20N8O2SPurity:98%Color and Shape:SolidMolecular weight:436.49CP-122288
CAS:<p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>Formula:C16H23N3O2SPurity:98%Color and Shape:SolidMolecular weight:321.44MAO A/HSP90-IN-1
CAS:MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.Formula:C24H29ClN2O4Purity:98%Color and Shape:SolidMolecular weight:444.95Adapiprazine
CAS:Adapiprazine is prochlorperazine that works as an anesthetic drug.Formula:C29H36ClN3SPurity:98%Color and Shape:SolidMolecular weight:494.13CDK4/6-IN-17
CAS:CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.Formula:C27H28F4N8Purity:98%Color and Shape:SolidMolecular weight:540.56ICMT-IN-49
CAS:ICMT-IN-49 (Compound 2) acts as an ICMT inhibitor with an IC50 value of 0.12 μM [1].Formula:C27H31NO3Color and Shape:SolidMolecular weight:417.54Duocarmycin Analog
CAS:<p>Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.</p>Formula:C34H31ClN4O5Purity:98%Color and Shape:SolidMolecular weight:611.09Icalcaprant
CAS:<p>Icalcaprant is a kappa-opioid receptor antagonist [1].</p>Formula:C23H26N4O3Purity:98%Color and Shape:SolidMolecular weight:406.48BChE/HDAC6-IN-1
CAS:BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6.Formula:C34H43N5O5Purity:98%Color and Shape:SolidMolecular weight:601.74G-38963
CAS:<p>G-38963 is a potent and highly specific MEK inhibitor (MEKi).</p>Formula:C16H13FIN3O4Color and Shape:SolidMolecular weight:457.2GNE-207
CAS:GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM).Formula:C29H30N6O3Purity:98%Color and Shape:SolidMolecular weight:510.59Arbemnifosbuvir
CAS:<p>Arbemnifosbuvir, a drug interfering with the nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12), is utilized</p>Formula:C24H33FN7O7PPurity:98%Color and Shape:SolidMolecular weight:581.53(S)-FTY720-phosphonate
CAS:<p>FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury.</p>Formula:C20H36NO4PPurity:98%Color and Shape:SolidMolecular weight:385.48Oxidized ATP trisodium salt
CAS:Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (Formula:C10H11N5Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:571.11BMS-986172
CAS:<p>BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM</p>Formula:C24H22F7N7O3Purity:98%Color and Shape:SolidMolecular weight:589.47Perindopril acyl-β-D-glucuronide
CAS:<p>Perindopril acyl-β-D-glucuronide is a metabolite of the ACE inhibitor perindopril [1].</p>Formula:C25H40N2O11Purity:98%Color and Shape:SolidMolecular weight:544.59TAK 029
CAS:TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.Formula:C19H23N5O7Color and Shape:SolidMolecular weight:433.42Beclin1-ATG14L interaction inhibitor 1
CAS:<p>Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.</p>Formula:C23H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:468.53JG-23
CAS:JG-23, a 4-chloro-modified analog, effectively induces t-tau degradation and demonstrates robust metabolic stability, exhibiting an extended half-life (T1/2) ofFormula:C19H16ClN3OS2Color and Shape:SolidMolecular weight:401.93LY 154045
CAS:LY 154045 is a selective antagonist of N-methylaspartate.Formula:C20H27NOColor and Shape:SolidMolecular weight:297.43YKL-5-124 TFA (1957203-01-8 free base)
YKL-5-124 TFA is a potent, selective, irreversible and covalent inhibitor of CDK7 (IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively).Formula:C30H34F3N7O5Purity:98%Color and Shape:SolidMolecular weight:629.63c-Met-IN-10
CAS:c-Met-IN-10: potent kinase inhibitor (IC50=16 nM), halts cancer cell activity/movement, induces apoptosis, for anticancer research.Formula:C26H21FN6O5Color and Shape:SolidMolecular weight:516.48AGN-190121
CAS:AGN-190121 is an RAR agonist that can synergize with RXR ligands to induce hypertriglyceridemia.Formula:C20H22O2Color and Shape:SolidMolecular weight:294.39WAY-328127
CAS:<p>WAY-328127 is an active molecule, exhibiting an inhibitory effect on the (11β-hydroxysteroid dehydrogenase type 1) [(11β-HSD1)] enzyme.</p>Formula:C15H15FN2O2Color and Shape:SolidMolecular weight:274.29Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Formula:C17H22BrNOS2Purity:98%Color and Shape:SolidMolecular weight:400.4KRAS G12C inhibitor 21
CAS:KRAS G12C inhibitor 21 is a KRAS G12C inhibitor.Formula:C34H30ClN3O4Color and Shape:SolidMolecular weight:580.07PLK1/BRD4-IN-1
CAS:PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).Formula:C31H43N9O2Color and Shape:SolidMolecular weight:573.73MB-28767
CAS:MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.Formula:C22H30O5Color and Shape:SolidMolecular weight:374.47URAT1 inhibitor 6
CAS:URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone,Formula:C9H7BrN3NaO2S2Color and Shape:SolidMolecular weight:356.2Methotrexate-γ-monoamide
CAS:Methotrexate-gamma-monoamide is a Methotrexate analog.Formula:C20H23N9O4Color and Shape:SolidMolecular weight:453.45Tyropeptin A-4
CAS:Tyropeptin A-4 is used as a proteasome inhibitor.Formula:C31H41N3O6Purity:98%Color and Shape:SolidMolecular weight:551.67TRC160334 sodium
CAS:TRC160334 is a HIF hydroxylases inhibitor.Formula:C14H15N3O5SColor and Shape:SolidMolecular weight:337.35Raluridine
CAS:Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.Formula:C9H10ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:264.64Crisdesalazine
CAS:Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1).Formula:C16H14F3NO3Purity:98.96%Color and Shape:SolidMolecular weight:325.28TIM-3-IN-2
CAS:<p>TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.</p>Formula:C25H23N3O6Purity:98.93%Color and Shape:SolidMolecular weight:461.47ALK5-IN-32
CAS:<p>ALK5-IN-32 selectively inhibits ALK-5 (IC50: 10-100 nM), blocks TGF-β/SMAD pathway, and may curb tumor growth, aiding proliferative disease research.</p>Formula:C23H23FN8Color and Shape:SolidMolecular weight:430.48F81-1144b
CAS:F81-1144b inhibits MMPs, cuts VLDL-TAG and TAG, reduces liver FA synthesis, and lowers insulin and glucose in serum.Formula:C27H37N3O5Color and Shape:SolidMolecular weight:483.6Henatinib
CAS:Henatinib: orally active multi-kinase inhibitor targeting VEGFR-2, c-kit, PDGFR with antitumor effects.Formula:C25H29FN4O4Color and Shape:SolidMolecular weight:468.52ZL-2201
CAS:<p>ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.</p>Formula:C20H25N9O5SPurity:98%Color and Shape:SolidMolecular weight:503.54PF-06862309
CAS:PF-06862309 is a PI3K inhibitorFormula:C20H26F3N8O7PColor and Shape:SolidMolecular weight:578.44MSI-1436
CAS:MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)Formula:C37H72N4O5SPurity:98%Color and Shape:SolidMolecular weight:685.06Oleoyl-L-carnitine chloride
CAS:<p>Oleoyl-L-carnitine, a long-chain acylcarnitine, acts as a selective inhibitor of glycine transporter 2 (GlyT2; IC50 = 340 nM) while demonstrating significantly</p>Formula:C25H48NO4·ClColor and Shape:SolidMolecular weight:462.11Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Formula:C30H31FN4O4SColor and Shape:SolidMolecular weight:562.65MEN-10573
CAS:MEN-10573 is a cyclic pseudopeptide and potent tachykinin NK-2 receptor antagonist.Formula:C45H56N8O8Color and Shape:SolidMolecular weight:836.97NCATS-SM1440
CAS:NCATS-SM1440 is a Lactate Dehydrogenase Inhibitor with Optimized Cell Activity and Pharmacokinetic Properties.Formula:C30H22F2N4O4S3Color and Shape:SolidMolecular weight:636.71PRMT5-IN-28
CAS:<p>PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes</p>Formula:C18H19ClN4O5Purity:98%Color and Shape:SolidMolecular weight:406.82WM-586
CAS:<p>WM-586 is a covalent inhibitor of WDR5 that impedes the WDR5-MYC binding.</p>Formula:C20H20F3N5O3SPurity:98%Color and Shape:SolidMolecular weight:467.47WAY-606376
CAS:WAY-606376 具有潜在的抗肿瘤活性，可用于研究免疫疾病。Formula:C18H13N3O2SPurity:99.48%Color and Shape:SolidMolecular weight:335.38FPL-65447 hydrochloride
CAS:FPL-65447 HCl is a D1 agonist for renal/cardiac failures and sepsis treatment.Formula:C17H22ClNO3Color and Shape:SolidMolecular weight:323.82CRX000227
CAS:<p>CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].</p>Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55Glycosidase-IN-2
CAS:Glycosidase-IN-2 is a glycosidase inhibitor with hypoglycemic activity.Formula:C13H23NO5Purity:98%Color and Shape:SolidMolecular weight:273.33Zaldaride (free base)
CAS:Zaldaride (free base) is a calmodulin antagonist.Formula:C26H28N4O2Color and Shape:SolidMolecular weight:428.53Demethylasterriquinone B1
CAS:insulin receptor (IR) activatorFormula:C32H30N2O4Purity:98%Color and Shape:SolidMolecular weight:506.59AR453588 hydrochloride
CAS:AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.Formula:C25H26ClN7O2S2Purity:98%Color and Shape:SolidMolecular weight:556.1CDK4/6-IN-15
CAS:CDK4/6-IN-15: Oral, selective CDK4/6 inhibitor, halts cancer cell growth, G1 arrest, suppresses Rb phosphorylation.Formula:C21H27FN8SColor and Shape:SolidMolecular weight:442.56Ulonivirine
CAS:Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.Formula:C18H8ClF6N5O3Color and Shape:SolidMolecular weight:491.73Duocarmycin MA
CAS:Duocarmycin MA: ADCs toxin for multi-drug resistant cells; DNA alkylating agent binding in DNA minor groove.Formula:C34H31ClN4O5Purity:98%Color and Shape:SolidMolecular weight:611.09TIE-2/VEGFR-2 kinase-IN-4
CAS:<p>TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting inhibitory</p>Formula:C26H17F4N5O4Color and Shape:SolidMolecular weight:539.44Naloxonazine dihydrochloride
CAS:μ1 receptor antagonistFormula:C38H43ClN4O6Purity:98%Color and Shape:SolidMolecular weight:687.22UZH1b
CAS:<p>UZH1b, an enantiomer of UZH1a (a METTL3 inhibitor), exhibits substantially reduced activity against METTL3, with an IC50 value of 28 µM [1].</p>Formula:C32H42N6O3Purity:98%Color and Shape:SolidMolecular weight:558.71Inogatran
CAS:Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.Formula:C21H38N6O4Purity:98%Color and Shape:SolidMolecular weight:438.56GSK-598809
CAS:GSK598809, a D3 receptor antagonist in Phase I trials, may lessen drug cravings by reducing reward cues.Formula:C23H25F4N5OSColor and Shape:SolidMolecular weight:495.54TBC-3486
CAS:TBC-3486 is a novel potent inhibitor of integrin α4, being 200-fold more potent in inhibiting α4β1 than α4β7.Formula:C27H31N3O6S2Color and Shape:SolidMolecular weight:557.68Cymipristone
CAS:Cymipristone, a progesterone receptor antagonist, is used potentially for termination of intrauterine pregnancy.Formula:C34H43NO2Purity:98%Color and Shape:SolidMolecular weight:497.71GRL-8234
CAS:GRL-8234 is a small-molecule BACE1 inhibitor that reverses memory impairments and age-related cognitive decline.Formula:C36H42N4O6SColor and Shape:SolidMolecular weight:658.81SC 53228
CAS:<p>SC 53228 is a specific leukotriene B4 receptor antagonist.</p>Formula:C31H41NO7Color and Shape:SolidMolecular weight:539.66Nampt-IN-10 TFA
CAS:Nampt-IN-10 TFA, a NAMPT inhibitor, shows potency in A2780 (IC50: 5 nM) and CORL23 (IC50: 19 nM), suitable for ADC payloads.Formula:C29H29F4N5O4Color and Shape:SolidMolecular weight:587.21557PF-915275
CAS:PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.Formula:C18H14N4O2SPurity:99.58% - 99.61%Color and Shape:SolidMolecular weight:350.39RO116-9132/238
CAS:<p>RO116-9132/238 is a bioactive chemical.</p>Formula:C28H40Cl2N3O4Color and Shape:SolidMolecular weight:553.54ICMT-IN-5
CAS:<p>ICMT-IN-5 (compound 46) is an ICMT inhibitor with an IC50 value of 0.3 μM [1].</p>Formula:C22H28FNOColor and Shape:SolidMolecular weight:341.46PF-02367982
CAS:<p>PF-02367982 is a potent, selective nonsteroidal progesterone antagonist.</p>Formula:C19H20N4O2Color and Shape:SolidMolecular weight:336.39Rohitukine
CAS:Rohitukine: anticancer, modulates apoptosis, antiadipogenic, antidyslipidemic, gastroprotective, antifertility, antileishmanial.Formula:C16H19NO5Color and Shape:SolidMolecular weight:305.33Maytansinoid B
CAS:<p>Maytansinoid B, an ADC cytotoxin, conjugates with antibodies to create antibody-drug conjugates (ADCs).</p>Formula:C36H51ClN4O10Color and Shape:SolidMolecular weight:735.26VU0652925
CAS:VU0652925 is a PAR4 antagonist. VU0652925 has a P-sel IC50 of 39.2 pM (-pIC50±SEM: 10.41±0.04) and a PAC1 IC50 of 43.0 pM (-pIC50±SEM: 10.4±0.04).Formula:C24H18N4O4S2Color and Shape:SolidMolecular weight:490.55RXFP1 receptor agonist-5
CAS:RXFP1 receptor agonist-5 (Example 98) is an agonist that targets the RXFP1 receptor and demonstrates its bioactivity by inhibiting cAMP production in HEK293Formula:C30H23F6N3O7Color and Shape:SolidMolecular weight:651.51Pristinamycin IA
CAS:Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.Formula:C45H54N8O10Purity:97.44%Color and Shape:SolidMolecular weight:866.96Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72MDK-0757
CAS:MDK-0757 is a novel inhibitor of heat shock protein 90 (Hsp90).Formula:C20H18FN5OPurity:98%Color and Shape:SolidMolecular weight:363.39BTK-IN-11
CAS:<p>BTK-IN-11: potent BTK inhibitor; may research autoimmune, inflammatory diseases, cancer. (Patent WO2022063101A1, Z2)</p>Formula:C26H22ClN5O3Color and Shape:SolidMolecular weight:487.94Gö 7874
CAS:Gö 7874 is a potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC).Formula:C27H26N4O4Color and Shape:SolidMolecular weight:470.52BMS-186511
CAS:BMS-186511: An FT inhibitor targeting malignant cells in NF1, halting growth and spread without affecting related enzymes.Formula:C34H60N3O7PSColor and Shape:SolidMolecular weight:685.89LY-393675
CAS:<p>LY-393675 is an antagonist of metabotropic glutamate receptor (mGluR).</p>Formula:C21H21NO4SColor and Shape:SolidMolecular weight:383.46HSP90-IN-27
CAS:<p>HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].</p>Formula:C18H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:343.44CIDD-0149897
CAS:<p>CIDD-0149897 is a potent, selective, and brain-penetrant agonist of ERβ that exhibits antitumor activity in glioblastoma [1].</p>Formula:C15H10FNO3Purity:98%Color and Shape:SolidMolecular weight:271.24Zelquistinel
CAS:Zelquistinel, an NMDA receptor agonist, aids research on depression, anxiety, and psychiatric disorders.Formula:C15H25N3O5Color and Shape:SolidMolecular weight:327.38LX7101
CAS:LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Formula:C23H29N7O3Purity:99.08%Color and Shape:SolidMolecular weight:451.52RET-IN-17
CAS:RET-IN-17 inhibits RET kinase; may help in IBS pain and RET-activated cancers.Formula:C27H28F4N4O4Color and Shape:SolidMolecular weight:548.53K-Ras G12C-IN-1
CAS:K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.Formula:C22H23Cl2N3O3Color and Shape:SolidMolecular weight:448.34Upadacitinib tartrate
CAS:Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.Formula:C21H33F3N6O11Purity:98%Color and Shape:SolidMolecular weight:602.521(2R,3S)-E1R
CAS:(2R,3S)-E1R, an enantiomer of E1R, is a sigma-1 receptor modulator for treating cognitive disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28L-163491
CAS:L-163491: partial agonist at angiotensin II receptor type 1, less so at type 2, used in research, may treat viral lung inflammation.Formula:C36H40N4O5SColor and Shape:SolidMolecular weight:640.79GSK737
CAS:<p>GSK737 is a dual inhibitor of BRD4 BD1 and BD2, exhibiting pIC50 values of 5.3 and 7.3, respectively.</p>Formula:C20H21N5O2Purity:98%Color and Shape:SolidMolecular weight:363.41ICMT-IN-22
CAS:ICMT-IN-22 (compound 62) acts as an ICMT inhibitor with an IC50 value of 0.63 μM [1].Formula:C22H28ClNO2Color and Shape:SolidMolecular weight:373.92HOE961
CAS:HOE961, a diacetate ester prodrug of S2242, is an oral anti-orthopoxvirus agent effective against cowpox.Formula:C13H17N5O5Color and Shape:SolidMolecular weight:323.3T145
CAS:T145 halts key bacteria growth at sub μg/ml, deters resistance, and may enhance drug lifespan.Formula:C18H16N2O5Purity:98%Color and Shape:SolidMolecular weight:340.33Co 102862
CAS:<p>Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.</p>Formula:C14H12FN3O2Purity:99.82%Color and Shape:SolidMolecular weight:273.26KRAS G12D modulator-1
CAS:KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and isFormula:C30H36FN5O4Purity:98%Color and Shape:SolidMolecular weight:549.64LY2780301
CAS:LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.Formula:C25H27F4N7OColor and Shape:SolidMolecular weight:517.52BT424
CAS:BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Formula:C22H15BCl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.08Atherospermidine
CAS:Atherospermidine is a smooth muscle relaxant aporphines from Artabotrys maingayi.Formula:C18H11NO4Color and Shape:SolidMolecular weight:305.28Uridine 5'-diphosphate
CAS:<p>Uridine 5'-diphosphate acts as a P2Y6 receptor agonist, exhibiting an EC50 value of 0.013 μM for the human P2Y6 receptor [1].</p>Formula:C9H14N2O12P2Purity:98%Color and Shape:SolidMolecular weight:404.16YG1702
CAS:YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Formula:C23H30N2O7SColor and Shape:SolidMolecular weight:478.56CD73-IN-10
CAS:CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.Formula:C15H13F2N5O2Color and Shape:SolidMolecular weight:333.29β-Catenin modulator-5
CAS:β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].Formula:C21H22N2O2SColor and Shape:SolidMolecular weight:366.48Eleven-Nineteen-Leukemia Protein IN-2
CAS:Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45MDL-72392
CAS:MDL-72392 is a monoamine oxidase inhibitor.Formula:C9H10FNOColor and Shape:SolidMolecular weight:167.18PF-05241328
CAS:PF-05241328 is an effective and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (IC50: 31 nM).Formula:C19H21ClN4O4SPurity:98%Color and Shape:SolidMolecular weight:436.91Furodysinin
CAS:<p>Furodysinin is an agonist of human leukotriene B4 receptor.</p>Formula:C15H20OColor and Shape:SolidMolecular weight:216.32CMP3a
CAS:CMP3a, a NEK2 inhibitor, hinders GBM in mice and enhances radiotherapy by disrupting EZH2.Formula:C28H27F3N6O2SColor and Shape:SolidMolecular weight:568.6110-Nitrolinoleic acid
CAS:10-Nitrolinoleate, a nitration product of linoleate, modulates PPARγ, enhancing glucose uptake, and aids in muscle relaxation via NO/cGMP pathway.Formula:C18H31NO4Color and Shape:SolidMolecular weight:325.44LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Formula:C16H27BN4O4Color and Shape:SolidMolecular weight:350.22AS1468240
CAS:AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.Formula:C25H25Cl2N5O3Color and Shape:SolidMolecular weight:514.45-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Formula:C19H23ClFNO2Purity:98%Color and Shape:SolidMolecular weight:351.84CDK7-IN-14
CAS:<p>CDK7-IN-14, a potent CDK7 inhibitor from pyrimidines, may treat transcriptionally dysregulated cancers (CN114249712A).</p>Formula:C22H24F3N6OPColor and Shape:SolidMolecular weight:476.43CC214-1
CAS:CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in vitro tool compound for exploring the biology of mTOR kinases.Formula:C20H21N7O2Purity:97.16%Color and Shape:SolidMolecular weight:391.43Sulfamidopyrine sodium salt
CAS:Sulfamidopyrine (Melaminsulfone) sodium salt, an active compound suitable for analytical study [1], is a variant of Sulfamidopyrine in its sodium salt form.Formula:C12H14N3NaO4SColor and Shape:SolidMolecular weight:319.31ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Formula:C9H15ClN2OColor and Shape:SolidMolecular weight:202.68PRMT5-IN-25
CAS:<p>PRMT5-IN-25 (compound 503) is a potent inhibitor of PRMT5, exhibiting an inhibition constant (K i) of 0.06 nM and demonstrating antiproliferative properties [1</p>Formula:C24H21F3N6OPurity:98%Color and Shape:SolidMolecular weight:466.4610β,17β-dihydroxyestra-1,4-dien-3-one
CAS:10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) has neuroprotective effects, can improve cognitive dysfunction, and can be used to study brain injury.Formula:C18H24O3Color and Shape:SolidMolecular weight:288.38THR-β agonist 1
CAS:THRβ Agonist 1 is a potent and selective THRβ agonist. THRβ Agonist 1 has the potential to be used in studies of thyroid hormone receptor related disorders.Formula:C17H14Cl2FN5O4Color and Shape:SolidMolecular weight:442.23Montelukast alcohol
CAS:Montelukast alcohol is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.Formula:C29H28ClNO2Color and Shape:SolidMolecular weight:457.99Antiarrhythmic agent-1
CAS:Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiacFormula:C25H27N3O4SColor and Shape:SolidMolecular weight:465.56ASP-4000 HCl
CAS:ASP-4000 HCl is an inhibitor of dipeptidyl peptidase 4 (DPP) with anti-hyperglycemic activity.Formula:C12H18ClN3O2Color and Shape:SolidMolecular weight:271.74NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Formula:C20H20O5Purity:98%Color and Shape:SolidMolecular weight:340.37PF-06250112
CAS:PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM.Formula:C22H20F2N6O2Purity:98%Color and Shape:SolidMolecular weight:438.43MEN-10612
CAS:<p>MEN-10612 is a cyclic pseudopeptide and potent tachykinin NK-2 receptor antagonist.</p>Formula:C43H60N8O6Color and Shape:SolidMolecular weight:784.99CT1113
CAS:CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDXFormula:C25H29N5O2SColor and Shape:SolidMolecular weight:463.6RUNX-IN-1
CAS:<p>RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their</p>Formula:C71H88Cl2N24O11Purity:98%Color and Shape:SolidMolecular weight:1524.52UCPH-102
CAS:<p>UCPH-102: Selective EAAT1 inhibitor, IC50 0.43 μM, treats Alzheimer's, ALS, chronic pain, OCD; crosses blood-brain barrier, targets T-ALL cells.</p>Formula:C21H18N2O2Color and Shape:SolidMolecular weight:330.38TRAP-6-IN-1
CAS:<p>TRAP-6-IN-1 inhibits collagen/TRAP-6, IC50: 17.12/11.88 μM, blocks platelet aggregation.</p>Formula:C18H20O3Color and Shape:SolidMolecular weight:284.35Ciprostene (free base)
CAS:Ciprostene, a stable prostacyclin analog, lowers blood pressure, increases heart rate, and inhibits platelets; tested in vascular disease patients.Formula:C22H36O4Color and Shape:SolidMolecular weight:364.52Vadaclidine
CAS:Vadaclidine is an orally acting antinociceptive muscarinic agonist.Formula:C13H21N3S2Color and Shape:SolidMolecular weight:283.46Antimalarial agent 10
CAS:<p>Compound 17b, an amino alcohol-quinoline, targets Pf3D7 (IC50: 14.9 nM) and PfW2 (IC50: 11 nM) with selectivity index >770.</p>Formula:C23H22F6N2O2Color and Shape:SolidMolecular weight:472.42SB 204070
CAS:Potent and selective 5-HT4 receptor antagonistFormula:C19H28Cl2N2O4Purity:98%Color and Shape:SolidMolecular weight:419.34Anti-osteoporosis agent-7
CAS:Compound 133, also known as Anti-osteoporosis agent-7, is a potential anti-osteoporosis agent that exhibits significant inhibition of osteoclast formation.Formula:C18H19Cl2NO3Color and Shape:SolidMolecular weight:368.25SARS-CoV-2-IN-44
CAS:<p>SARS-CoV-2-IN-44, an inhibitor of SARS-CoV-2, effectively suppresses viral replication with an EC50 value of 0.6μM and exhibits negligible cytotoxicity in Calu-</p>Formula:C18H16O5Purity:98%Color and Shape:SolidMolecular weight:312.32Thaspine acetate
CAS:Thaspine: inhibits topoisomerase IB, reduces VEGF, stops endothelial cell growth via PI3K/MAPK pathways.Formula:C22H23NO8Color and Shape:SolidMolecular weight:429.425O-2050
CAS:O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.Formula:C23H31NO4SPurity:98%Color and Shape:SolidMolecular weight:417.56BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Color and Shape:SolidMolecular weight:518.5GS-6201
CAS:GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor.Formula:C21H21F3N6O2Purity:99.78% - 99.94%Color and Shape:SolidMolecular weight:446.43pan-KRAS-IN-2
CAS:Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12DFormula:C34H34F2N4O3Purity:98%Color and Shape:SolidMolecular weight:584.66GSK2973980A
CAS:GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).Formula:C25H19F5N4O4Purity:98%Color and Shape:SolidMolecular weight:534.43Lepadin H
CAS:Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancingFormula:C26H45NO3Purity:98%Color and Shape:SolidMolecular weight:419.64EMD638683 S-Form
CAS:EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 S-Form is the S-form of EMD638683.Formula:C18H18F2N2O4Color and Shape:SolidMolecular weight:364.34BMS-561390
CAS:<p>BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formula:C14H12ClF3N2OColor and Shape:SolidMolecular weight:316.71Lysyl-aspartyl-glutamyl-leucine
CAS:Lysyl-aspartyl-glutamyl-leucine maintains type II surface membrane proteins in the endoplasmic reticulum.Formula:C21H37N5O9Color and Shape:SolidMolecular weight:503.55Lp-PLA2-IN-9
CAS:Lp-PLA2-IN-9, a tetracyclic pyrimidinone, inhibits rhLp-PLA2 (pIC50: 10.1), promising for neurodegenerative research.Formula:C25H19ClF5N3O4Color and Shape:SolidMolecular weight:555.88JNJ-10258859
CAS:JNJ-10258859 is a potent, and selective phosphodiesterase type 5 inhibitor with a K(i) of 0.23 nM.Formula:C30H24N4O3Color and Shape:SolidMolecular weight:488.54LGD-2941
CAS:LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.Formula:C17H16F6N2O2Color and Shape:SolidMolecular weight:394.31NK3R-IN-1
CAS:<p>NK3R-IN-1 (compound 16x), an orally active imidazolepiperazine derivative, acts as a Neurokinin Receptor NK3R inhibitor and has been shown to reduce blood</p>Formula:C17H16FN5OSPurity:98%Color and Shape:SolidMolecular weight:357.41Galectin-3 antagonist 2
CAS:<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Formula:C22H23NO10Purity:98%Color and Shape:SolidMolecular weight:461.42CYP17-IN-1
CAS:<p>CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.</p>Formula:C18H17FN2SPurity:99.14% - 99.83%Color and Shape:SolidMolecular weight:312.4ALP/Carbonic anhydrase-IN-1
CAS:<p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>Formula:C15H16N2Purity:98%Color and Shape:SolidMolecular weight:224.3SARS-CoV-2 3CLpro-IN-11
SARS-CoV-2 3CLpro-IN-11, potent inhibitor: IC50 of 140nM for 3CLpro; 240nM for SARS-CoV-1; 70nM for MERS-CoV; broad-spectrum antiviral.Formula:C25H36N3NaO9SColor and Shape:SolidMolecular weight:577.62WEE1-IN-4
CAS:Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor.Formula:C20H11ClN2O3Color and Shape:SolidMolecular weight:362.77FEN1-IN-5
CAS:<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Formula:C21H17N3O4SPurity:98%Color and Shape:SolidMolecular weight:407.44NBI-961
CAS:NBI-961, a potent NEK2 inhibitor, suppresses proteasomal degradation and effectively induces G2/mitosis arrest and apoptosis within diffuse large B cellFormula:C28H27F3N6O2SColor and Shape:SolidMolecular weight:568.61HSD17B13-IN-2
CAS:<p>HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1</p>Formula:C21H23F2NO4Color and Shape:SolidMolecular weight:391.41SM-32504
CAS:SM-32504 is a potent inhibitor of ACAT.Formula:C32H38N4O3Purity:98%Color and Shape:SolidMolecular weight:526.67Nivocasan
CAS:<p>Nivocasan (GS-9450/LB-84451), a caspase-inhibitor, reduces ALT in NASH, shows hepatoprotective effects in fibrosis models.</p>Formula:C21H22FN3O5Color and Shape:SolidMolecular weight:415.41PHD-IN-2
CAS:<p>PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of</p>Formula:C26H27N7O4Purity:98%Color and Shape:SolidMolecular weight:501.54NMS-P953
CAS:NMS-P953: JAK2 inhibitor, reduces tumor growth in SET-2 model, confirmed in vivo action, good pharmacokinetics and safety.Formula:C16H11ClF3N5OColor and Shape:SolidMolecular weight:381.74MF 13
CAS:MF 13 exhibits tumor apoptosis activity.Formula:C23H34Cl2N4O4Color and Shape:SolidMolecular weight:501.45BAY-R 1005
CAS:<p>BAY-R 1005, a synthetic glycolipid analogue (GLA) with immunoenhancing properties, is designed to modulate antibody synthesis [1].</p>Formula:C44H87N3O8Color and Shape:SolidMolecular weight:786.18Cyclic HPMPC
CAS:Cyclic HPMPC: Potent antiviral, raises O2 in mice with lethal vaccinia, lowers guinea pig CMV replication.Formula:C8H12N3O5PColor and Shape:SolidMolecular weight:261.17R1498
CAS:<p>R1498 inhibits CDK2, targets angiogenesis and mitosis, and is an oral treatment for liver and stomach cancer.</p>Formula:C18H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:338.79S 16020-2
CAS:<p>S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors.</p>Formula:C22H26Cl2N4O2Color and Shape:SolidMolecular weight:449.376Lifirafenib
CAS:Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinantFormula:C25H17F3N4O3Purity:97.99% - 98%Color and Shape:SolidMolecular weight:478.42WRN inhibitor 4
CAS:<p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formula:C16H14N2O5SColor and Shape:SolidMolecular weight:346.36Firuglipel
CAS:<p>Firuglipel is an orally available and selective agonist of GPR119.</p>Formula:C25H26FN3O5Purity:98%Color and Shape:SolidMolecular weight:467.49DuP-532
CAS:<p>DuP-532, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension and heart failure.</p>Formula:C23H19F5N6O2Color and Shape:SolidMolecular weight:506.43DosatiLink-1
CAS:<p>DosatiLink-1 acts as an inhibitor of the Abelson murine leukemia (ABL) enzyme [1].</p>Formula:C69H93Cl2F2N13O17SColor and Shape:SolidMolecular weight:1517.52CI-949
CAS:<p>CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).</p>Formula:C20H20N6O3Purity:98%Color and Shape:SolidMolecular weight:392.41AMG151 HCl
CAS:<p>ARRY-403 (AMG-151) is an oral glucokinase activator for type 2 diabetes with an EC50 of 79 nM and favorable drug properties.</p>Formula:C20H20Cl2N6O3S2Color and Shape:SolidMolecular weight:527.4392-Furoyl-LIGRLO-amide TFA
CAS:2-Furoyl-LIGRLO-amide TFA is a potent and selective agonist of the proteinase-activated receptor 2 (PAR2), exhibiting a pD2 value of 7.0 [1] [2].Formula:C38H64F3N11O10Color and Shape:SolidMolecular weight:891.98A-357300
CAS:A-357300: potent reversible MetAP2 inhibitor, IC50=0.12 uM; promising for neuroblastoma treatment.Formula:C15H22ClN3O3SColor and Shape:SolidMolecular weight:359.87SARS-CoV-2-IN-1
CAS:SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 and 0.58 μM, respectively).Formula:C31H39N5O7Purity:98%Color and Shape:SolidMolecular weight:593.67P2X3 antagonist 38
CAS:<p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>Formula:C22H25F3N6O3Purity:98%Color and Shape:SolidMolecular weight:478.47AGN194204
CAS:AGN194204 (IRX4204), an oral RXR agonist, inactive against RAR, has Kd 0.4-3.8 nM & EC50 0.08-0.8 nM, with anti-inflammatory and anticarcinogenic properties.Formula:C24H32O2Purity:98%Color and Shape:SolidMolecular weight:352.51Fervenulin
CAS:<p>Fervenulin, from Streptomyces sp. CMU-MH021, halts egg hatch (MIC: 30 μg/mL) and kills J2 larvae (MIC: 120 μg/mL) of M. incognita.</p>Formula:C7H7N5O2Purity:99.75%Color and Shape:SolidMolecular weight:193.16
