Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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Tazarotene
CAS:<p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Formula:C21H21NO2SColor and Shape:Light YellowMolecular weight:351.46rac Phenylephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Phenylephrine is a selective α1-adrenergic receptor agonist used as a decongestant. Phenylephrine lowers intraocular pressure and is used as an agent to dilate the pupil.<br>References Lorenzetti, O.J. et al.: Exp. Eye Res., 12, 80 (1971); Ando, J. et al.: Nip. Yakur. Zas., 61, 471 (1965);<br></p>Formula:C9H14ClNO2Color and Shape:NeatMolecular weight:203.676-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one
CAS:Purity:98.0%Molecular weight:475.8500061035156Ref: 10-F549703
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire5-Chloro Dasatinib
CAS:Controlled ProductFormula:C22H25Cl2N7O2SColor and Shape:NeatMolecular weight:522.453-Rhodanineacetic Acid
CAS:Controlled ProductFormula:C5H5NO3S2Color and Shape:NeatMolecular weight:191.23rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS:Controlled Product<p>Impurity Metoprolol USP Related Compound B<br>Applications An intermediate for the synthesis of β-chlorohydrins and β-chloroamines. An impurity found in metoprolol. Metroprolol USP Related Compound B.<br>References Moore, R., et al.: Marine Natural Products, 1, 43 (1978),<br></p>Formula:C12H17ClO3Color and Shape:ColourlessMolecular weight:244.71(R)-Sulindac
CAS:Controlled Product<p>Applications (R)-Sulindac is the R-epimer metabolite of Sulinac (S699215). (S)-Sulindac increases the activity of the P 450 system better than (R)-Sulindac, but both epimers increase primarily the enzymes that oxidize (R)-Sulindac.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Duggan, D., et al.: J. Pharmacol. Exp. Ther., 1977, 201, 8 (1977), Hamman, M., et al.: Biochem. Pharmacol., 60, 7 (2000), Grimaud, R., et al.: J. Biol. Chem., 276, 48915 (2001),<br></p>Formula:C20H17FO3SColor and Shape:NeatMolecular weight:356.417-Chloro-1-Ethyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Ethyl Ester
CAS:Controlled Product<p>Impurity Norfloxacin Impurity 5<br>Applications 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester (Norfloxacin Impurity 5) is an impurity of Norfloxacin (N681000), an antibacterial agent and a contaminant of emerging concern (CECs).<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Formula:C14H13ClFNO3Color and Shape:Off-White To BeigeMolecular weight:297.71Diclazuril 6-Carboxamide
CAS:Controlled Product<p>Applications Diclazuril 6-Carboxamide is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br></p>Formula:C18H10Cl3N5O3Color and Shape:NeatMolecular weight:450.66Methylphenidate Hydrochloride
CAS:Controlled Product<p>Applications Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methylphenidate exhibits the pharmacologically usually desired effects. This compound is a 4:1 mixture of rac-erythro (M325670) and rac-threo (M325671).<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formula:C14H19NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:269.773-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
CAS:Controlled ProductFormula:C6H5F3N4OColor and Shape:Off White To Light GreyMolecular weight:206.136-(Butylamino)-N-(2,6-dimethylphenyl)hexanamide
CAS:Controlled Product<p>Applications 6-(Butylamino)-N-(2,6-dimethylphenyl)hexanamide is a structural isomer of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Formula:C18H30N2OColor and Shape:White To Off-WhiteMolecular weight:290.44rac Efavirenz
CAS:<p>Applications rac Efavirenz is a mixture of both enantiomers for Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995); Hadaruga, D. et al.: J. Med Chem., 48, 2432 (2005);<br></p>Formula:C14H9ClF3NO2Color and Shape:NeatMolecular weight:315.684-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide
CAS:<p>Impurity Amisulpride EP Impurity G<br>Applications 4-Amino-N-(1-ethyl-3-piperidinyl)-5-(ethylsulfonyl)-2-methoxybenzamide is an impurity of Amisulpride (A633250). Amisulpride EP Impurity G<br></p>Formula:C17H27N3O4SColor and Shape:Off White PowderMolecular weight:369.479Sitagliptin Carbamoyl β-D-Glucuronide Sodium Salt
CAS:Controlled ProductFormula:C23H22F6N5NaO9Color and Shape:NeatMolecular weight:649.431-Methyl-3-phenylpiperazine
CAS:Controlled Product<p>Applications Piperazine derivative used as reference materials for forensic laboratories. They affect the central and the autonomic nervous systems, the blood pressure, and smooth muscle.<br>References Brady, J., et al.: Drug Dev. Res., 20, 231 (1990), Winter, J., et al.: J. Pharmacol. Exp. Ther., 262, 682 (1992), Ator, N., et al.: Eur. J. Pharmacol., 241, 237 (1993), Forster, E., et al.: Eur. J. Pharmacol., 281, 81 (1995),<br></p>Formula:C11H16N2Color and Shape:Off WhiteMolecular weight:176.26Desmethyl Nintedanib
CAS:Controlled Product<p>Applications Desmethyl Nintedanib is an impurity of Intedanib (I666650), which is an antitumor agent. Desmethyl Nintedanib was used in the study of synthesizing indolinones as triple angiokinase inhibitors.<br>References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009);<br></p>Formula:C30H31N5O4Color and Shape:NeatMolecular weight:525.6N-Desbutyl Bupivacaine
CAS:Controlled Product<p>Impurity Bupivacaine USP Related Compound B<br>Applications N-Desbutyl Bupivacaine (Bupivacaine USP Related Compound B) is a major metabolite of Bupivacaine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bargetzi, M.J., et al.: Clin. Pharmacol. Ther., 46, 521 (1989), Shimada, T., et al.: J. Pharmacol. Exp. Ther., 270, 414 (1994), Attolini, L., et al.: Fundam. Clin. Pharmacol., 11, 152 (1997),<br></p>Formula:C14H20N2OColor and Shape:White To Light BeigeMolecular weight:232.32N-(4-Aminobenzoyl)-β-alanine
CAS:Controlled Product<p>Impurity Balsalazide Aminobenzoyl Impurity<br>Applications N-(4-aminobenzoyl)-β-Alanine is a metabolite of BX661A, a therapeutic agent used in the treatment of ulcerative colitis, chemotaxis and reactive oxygen species production in polymorphonuclear leukocyctes. Inhibits lipid peroxidation in large intestinal mucosa after mesenteric ischemia/reperfusion.<br>References Kimura, I. et al.: Arzneimittelforschung., 48, 1007 (1998); Kumamoto, T. et al.: Jpn. J. Pharmacol., 75, 187 (1997);<br></p>Formula:C10H12N2O3Color and Shape:NeatMolecular weight:208.21N-(2-Hydroxyethyl)nicotinamide
CAS:Controlled Product<p>Applications N-(2-Hydroxyethyl)nitotinamide is an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.<br>References Boschi, D., et al.: Bioorg. Med. Chem., 8, 1727 (2000); Nagai, H., et al.: Chem. Pharm. Bull., 32, 1063 (1984); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)<br></p>Formula:C8H10N2O2Color and Shape:NeatMolecular weight:166.18Ethyl 2-amino-2-(3-chloropyridin-4-yl)acetate hydrochloride
CAS:Purity:97.0%Molecular weight:251.11000061035156Pomalidomide-(d4 major)
CAS:Controlled Product<p>Applications Pomalidomide-d4 is the labeled anaxlogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Formula:C13H7D4N3O4Color and Shape:NeatMolecular weight:277.274-Desmethyl-3-methyl Celecoxib
CAS:Controlled Product<p>Impurity Celecoxib Related Compound A<br>Applications 4-Desmethyl-3-methyl Celecoxib is a meta positional isomer of Celecoxib (C251000) with selective inhibitory activity against human cyclooxygenase-2. USP Celecoxib Related Compound A<br>References Sreenivas, R.D. et al.: J. Pharmac. Biomed. Anal., 25, 21 (2001);<br></p>Formula:C17H14F3N3O2SColor and Shape:White To Light YellowMolecular weight:381.37Axitinib Iodo Tetrahydropyran
Controlled Product<p>Applications Axitinib Iodo Tetrahydropyran is an analog of Axitinib (A794650). Axitinib (A794650) is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003);Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);<br></p>Formula:C19H20IN3OColor and Shape:NeatMolecular weight:433.286(±)-Albuterol-d3 (3-hydroxymethyl-d2; α-d1)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (±)-Albuterol-d3 (3-hydroxymethyl-d2; alpha-d1) (CAS# 1219798-60-3) is a useful isotopically labeled research compound.<br></p>Formula:C132H3H18NO3Color and Shape:Off-WhiteMolecular weight:242.33Regorafenib
CAS:Controlled Product<p>Applications It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Dual action VEGFR & Raf inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000),<br></p>Formula:C21H15ClF4N4O3Color and Shape:Off White PowderMolecular weight:482.824-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
CAS:Purity:98%Molecular weight:534.6649780273438Clozapine-d4
CAS:Controlled Product<p>Applications Clozapine-d4 can act as modulators of dopamine receptors, serotonin receptors, adrenergic receptors, acetylcholine receptors, and/or histamine receptors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gant, T. G., U.S. Pat. Appl. Publ. (2010), US 20100166887 A1, 20100701<br></p>Formula:C182H4H15ClN4Color and Shape:Light Yellow To YellowMolecular weight:330.85Dehydro Aripiprazole
CAS:Controlled Product<p>Impurity Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G<br>Applications Dehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Zeidan, T.A., et al.: Crystal. Growth. Design., 13, 2036 (2013); Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);<br></p>Formula:C23H25Cl2N3O2Color and Shape:Off-WhiteMolecular weight:446.37Omeprazole sulfide N-Oxide
CAS:<p>Applications 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:Off-WhiteMolecular weight:345.422-(Piperazin-1-yl)acetic acid N-(2-pyridyl)amidetrihydrochloride dihydrate
CAS:Formula:C11H23Cl3N4O3Color and Shape:SolidMolecular weight:365.684-Phenyl-2-(pyrazin-2-yl)-1,3-thiazole-5-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:283.30999755859375Dehydro Amlodipine Oxalate
CAS:Controlled ProductFormula:C20H23ClN2O5·C2H2O4Color and Shape:White To Off-WhiteMolecular weight:496.89(+/-)-4-Hydroxy Mephenytoin-d3
CAS:Controlled Product<p>Applications A deuterated CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formula:C12H11D3N2O3Color and Shape:White To Off-WhiteMolecular weight:237.274-(1-piperazinyl)quinazoline dihydrochloride dihydrate
Purity:95.0%Molecular weight:323.22000122070318-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione
CAS:<p>Applications 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.<br>References Sutton, J., et al.: Bioorg. Med. Chem. Lett., 22, 1464 (2012); Lai, Z., et al.: Eur. J. Med. Chem., 83, 547 (2014)<br></p>Formula:C20H17BrN6O2Color and Shape:NeatMolecular weight:453.29(R)-Methotrimeprazine
CAS:Controlled ProductFormula:C19H24N2OSColor and Shape:NeatMolecular weight:328.473,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone
CAS:Controlled Product<p>Impurity Aripiprazole Butanoic Acid Impurity<br>Applications 3,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone is a metabolite of Aripiprazole (A771000); a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Also an antipsychotic. Aripiprazole Butanoic Acid Impurity<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998); Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998)<br></p>Formula:C13H15NO4Color and Shape:Off-WhiteMolecular weight:249.26rac FTY720 Phosphate
CAS:Controlled Product<p>Applications rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration.<br>References Igarashi, J., et al.: J. Biol. Chem., 275, 32363 (2000), Bandhuvula, P., et al.: J. Biol. Chem., 280, 33697 (2005),<br></p>Formula:C19H34NO5PColor and Shape:NeatMolecular weight:387.45Thiophene
CAS:Controlled Product<p>Applications Thiophene is used as a building block of various organic molecules and pharmaceuticals providing functional properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prasad, B. et al.: Chem. Comm., 48, 10434 (2012); Freitas, V. et al.: Struct. Chem., 24, 661 (2013);<br></p>Formula:C4H4SColor and Shape:ColourlessMolecular weight:84.14Genfatinib-d3 (Imatinib-d3)
CAS:Controlled Product<p>Applications Genfatinib-d3 (Imatinib-d3) is the labeled analogue of Genfatinib, a treatment of chronic myeloid leukemia (CML). It is a COVID19-related research product.<br>References Helmann, R., et. al.: J. Clin. Oncol., 32, 415 (2014)<br></p>Formula:C29D3H28N7OColor and Shape:NeatMolecular weight:496.62FG 2216
CAS:Controlled Product<p>Applications FG 2216 is an erythropoietic agent which is orally active prolyl-hydroxylase inhibitor which increases erythropoietin production in end-stage kidney disease.<br>References Bernhardt, W., et al.: J. Am. Soc. Nephrol., 21, 2151 (2010)<br></p>Formula:C12H9ClN2O4Color and Shape:WhiteMolecular weight:280.6645-Bromo-quinolin-8-ylamine hydrochloride
CAS:Formula:C9H8BrClN2Purity:95.0%Color and Shape:SolidMolecular weight:259.53Tofacitinib impurity N
CAS:Controlled Product<p>Impurity Tofacitinib Impurity (T528000)<br>Applications Tofacitinib impurity N is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.<br>References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)<br></p>Formula:C13H19N5Color and Shape:NeatMolecular weight:245.327-(Benzyloxy)quinolin-4-ol
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:251.28500366210938[2-(1H-indol-3-yl)ethyl](3-pyridinylmethyl)amine hydrobromide
CAS:Purity:95.0%Molecular weight:332.244995117187511-Morpholino-dibenzo[b,f][1,4]thiazepine
CAS:Controlled Product<p>Applications 11-Morpholino-dibenzo[b,f][1,4]thiazepine is part of a group of 11-(substituted-amino)dibenzo[b,f][1,4]thiazepine compounds that have analgesic and sedative properties.<br>References Schmutz, J. & Hunziker, F.: Patentschrift (Switz.), 7pp. (1969)<br></p>Formula:C17H16N2OSColor and Shape:NeatMolecular weight:296.39Linuron-d6
CAS:Controlled Product<p>Applications Labelled analog of a restricted use pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bradford, D., et al.: Environ. Sci. Technol., 44, 4609 (2010), Trtic-Petrovic, T., et al.: Anal. Bioanal. Chem., 397, 2233 (2010), Stewart, C., et al.: Weed Biol. Man., 10, 40 (2010),<br></p>Formula:C92H6H4Cl2N2O2Color and Shape:Off-WhiteMolecular weight:255.136-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-((1-methylpiperidin-4-yl)amino)quinazolin-7-ol (trihydrochloride)
Purity:98%Molecular weight:509.9(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS:<p>Applications (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.<br>References Chen, W., et al.: PCT Int. Appl. (2011), WO 2011046964 A2 20110421<br></p>Formula:C22H22N6OColor and Shape:White To Light YellowMolecular weight:386.454-(4-Bromophenyl)pyrazole
CAS:Formula:C9H7BrN2Purity:95.0%Color and Shape:SolidMolecular weight:223.073rac Penbutolol-d9
CAS:Controlled Product<p>Applications Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Formula:C18H20D9NO2Color and Shape:White To Off-WhiteMolecular weight:300.48[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol
CAS:Controlled Product<p>Applications [2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol is used in the preparation of azepine.<br>References Lypacewicz, Maria K. et al., Pol.(1998);<br></p>Formula:C18H22N2OColor and Shape:White To Light BeigeMolecular weight:282.38Indigo Carmine
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Indigo carmine is a dye consisting of an indigo dimer with sodium salts of sulfonic acids at positions 5 and 5'. This compound has been used as a tissue stain, pH indicator, and tool for the determination of hypochlorite in solutions.<br>References 1. Reinle, G.G. and Depuy, E.S. 1920. Cal State J Med. 18: 49-52. PMID: 187381042. Monson, F.C., et al. 1991. J. Urol. 145: 842-845. PMID: 20057163. Harriram, A., et al. 2003. J Environ Sci Health A Tox Hazard Subst Environ Eng. 3: 1055-1064. PMID: 127749084. Archer, T.L. 2009. J Clin Anesth. 21: 544-546. PMID: 200062695. Lee, B.E., et al. 2010. BMC Gastroenterol. 10 97. PMID: 207318306. Park, H.J., et al. 2010. J Clin Ultrasound. 38: 305-308. PMID: 20544866<br></p>Formula:C16H8N2O8S2·2NaColor and Shape:NeatMolecular weight:466.35Tenoxicam
CAS:Controlled Product<p>Applications Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Formula:C13H11N3O4S2Color and Shape:NeatMolecular weight:337.37Olaquindox
CAS:<p>Applications A growth stimulant.<br>References Barber, R.S., et al.: Anim. Feed Sci. Technol., 4, 117 (1979), Kwaga, J., et al.: Antimicrob. Agents Chemother., 34, 2423 (1990), Hugot, J., et al.: Lancet, 362, 2012 (2003),<br></p>Formula:C12H13N3O4Color and Shape:NeatMolecular weight:263.25Desamino Imiquimod N-Oxide
CAS:Controlled Product<p>Impurity Imiquimod USP Related Compound B<br>Applications Desamino Imiquimod N-Oxide (Imiquimod USP Related Compound B) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formula:C14H15N3OColor and Shape:NeatMolecular weight:241.297-chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:298.73001098632814-ethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875Etoricoxib N1’-Oxide
CAS:Controlled Product<p>Applications Etoricoxib N1’-Oxide is an impurity of Etoricoxib (E934100).<br>References Friesen, R., et al.: Bioorg. Med. Lett., 8, 2777 (1998), Botting, J., et al.: Drugs of Today, 35, 225 (19990, Talley, J., et al.: J. Med. Chem., 43, 775 (2000),<br></p>Formula:C18H15ClN2O3SColor and Shape:NeatMolecular weight:374.84Sodium Azide
CAS:<p>Applications Sodium azide is commonly used as a preservative in aqueous laboratory reagents and biological samples. Sodium azide’s toxicity can be attributed to its role as a reversible inhibitor of mitochondrial respiration and insulin secretion in human pancreatic cells. Acts as a catalyst for: Oxidative decarboxylation & Michael addition reactions.Used as a reagent for synthesis of Blue fluorescent copolymers; Metal phosphonates & Arenes via aminations. Actively involved in regioselective synthesis of prianosin B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, S. & Lamm, S.: Int. J. Toxicol., 22, 175 (2003); Misler, S., et al.: Pflügers Archiv., 421, 289 (1992)<br></p>Formula:N3·NaColor and Shape:White To Off-WhiteMolecular weight:65.012-[5-(Trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
CAS:Purity:97.0%Molecular weight:263.190002441406254-tert-Butylacetophenone
CAS:Controlled Product<p>Applications 4-tert-Butylacetophenone is an impurity arising in the synthesis of Ebastine (E320000). Ebastine impurity B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C12H16OColor and Shape:ColourlessMolecular weight:176.2510H-Phenothiazine 5-Oxide
CAS:<p>Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.<br>References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)<br></p>Formula:C12H9NOSColor and Shape:Light Beige To Light BrownMolecular weight:215.276-Amino-1,3-dimethyluracil
CAS:Controlled Product<p>Applications 6-Amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. It is also used as a starting material in the synthesis of fused pyrido-pyrimidines.<br>References Abu-Hashem, A., et al.: Lett. Drug. Des. Discov., 12, 471 (2015); Azev, Y., et al.: Mendeleev Commun., 25, 310 (2015)<br></p>Formula:C6H9N3O2Color and Shape:Light YellowMolecular weight:155.15Mebeverine Alcohol
CAS:Controlled Product<p>Applications A metabolite of Mebeverine (M202490), an antispasmodic.<br>References Greenwood, B., et al.: Eur. J. Pharmacol., 211, 143 (1992), van Outryve, M., et al.: J. Clin. Pharm. Ther., 20, 277 (1995), Kraemer, T., et al.: Drug Metab. Disp., 28, 339 (2000),<br></p>Formula:C16H27NO2Color and Shape:NeatMolecular weight:265.391,3-Dimethyl Barbituric Acid
CAS:Controlled Product<p>Applications 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid (B118650). All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.<br>References Gupta, K., et al.: Eur. J. Med. Chem., 17, 448 (1982), Weber, L., et al.: Curr. Med. Chem., 9, 2085 (2002), Skiles, J., et al.: Curr. Med. Chem., 11, 2911 (2004),<br></p>Formula:C6H8N2O3Color and Shape:NeatMolecular weight:156.14Pyrazinenitrile
CAS:Controlled Product<p>Impurity Pyrazinamide EP Impurity B<br>Applications Pyrazinenitrile (Pyrazinamide EP Impurity) is used as a single-source precursor in the synthesis of metal-free nitrogen-doped carbon nanoparticles (NCNPs). Also, it is an important intermediate in the production of pyrazinamide as an effective anti-tubercular drug.<br>References Panomsuwan, G., et al.: Carbon, 98, 411-420 (2016); Radnik, J., et al.: Catal. Commun., 71, 97-101 (2015);<br></p>Formula:C5H3N3Color and Shape:ColourlessMolecular weight:105.14-Cyanopyridine
CAS:Controlled Product<p>Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.<br>References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)<br></p>Formula:C6H4N2Color and Shape:WhiteMolecular weight:104.11Prothipendyl-d6 Hydrochloride
CAS:Controlled Product<p>Applications A labelled Phenothiazine (P318040) analog. Antipsychotic.<br>References Sartorelli, A.C., et al.: Experientia, 21, 457 ( 1965),<br></p>Formula:C16H13D6N3S•HClColor and Shape:NeatMolecular weight:291.443646Nitrendipine Propyl Ester
CAS:Controlled Product<p>Applications Nitrendipine Propyl Ester is an analogue of the antihypertensive drug Nitrendipine (N490150). Also, Nitrendipine Propyl Ester is an impurity of antihypertensive Lercanidipine (L179000). Lercanidipine impurity A.<br>References Ashimori, A., et al.: Chem. Pharm. Bull., 39, 108 (1991), Baindur, N., et al.: J. Med. Chem., 36, 3743 (1993), Zhang, B., et al.: Bioorg. Med. Chem. Lett., 20, 805 (2010),<br></p>Formula:C19H22N2O6Color and Shape:NeatMolecular weight:374.395,6,7,8-Tetradehydro Risperidone
CAS:Controlled Product<p>Applications 5,6,7,8-Tetradehydro Risperidone is an impurity of risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formula:C23H23FN4O2Color and Shape:NeatMolecular weight:406.454-(Methylsulfonyl)phenylacetic Acid
CAS:Controlled Product<p>Applications 4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.<br>References Eren, G., et al.: Bioorg. Med. Chem., 18, 6467 (2010); Weber, V., et al.: Bioorg. Med. Chem., 13, 4552 (2005)<br></p>Formula:C9H10O4SColor and Shape:NeatMolecular weight:214.24rac-Monepantel
CAS:Controlled Product<p>Applications rac-Monepantel is a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Formula:C20H13F6N3O2SColor and Shape:Off White SolidMolecular weight:473.391-[2-(2-Hydroxyethoxy)ethyl]piperazine
CAS:Formula:C8H18N2O2Color and Shape:NeatMolecular weight:174.24Rotigotine
CAS:<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Formula:C19H25NOSPurity:99.04% - 99.88%Color and Shape:SolidMolecular weight:315.475-Naphthalen-1-yl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Purity:95.0%Molecular weight:252.2729949951172TERT-BUTYL 3-(THIOPHEN-2-YL)PYRROLIDINE-1-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:253.360000610351562-Thiophenecarbonyl chloride
CAS:Formula:C5H3ClOSPurity:95%Color and Shape:LiquidMolecular weight:146.596,7-Bis(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbonitrile
CAS:Purity:98%Molecular weight:382.419006347656251,5-Dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:167.164001464843753-methyl-4-oxo-3,4-dihydro-7-quinazolinecarboxylic acid
CAS:Purity:95.0%Molecular weight:204.18499755859375Ref: 10-F311697
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