Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Atorvastatin Impurity 110 Calcium Salt
CAS:Formula:C35H39FN2O5C35H39FN2O5·5CaMolecular weight:586.70 0.5*40.08Cetilistat
CAS:<p>Cetilistat (ATL-962) is a drug for obesity and type 2 diabetes, blocking pancreatic lipase. Developed by Alizyme.</p>Formula:C25H39NO3Purity:97.12% - 97.47%Color and Shape:Off-White CrystMolecular weight:401.582-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formula:C11H11F3N2O4Purity:99.45% - 99.82%Color and Shape:SolidMolecular weight:292.21Torcetrapib
CAS:<p>Torcetrapib (CP-529414), a CETP inhibitor, curbs cholesteryl ester movement from HDL to LDL/VLDL; failed Phase III trials due to mortality increase.</p>Formula:C26H25F9N2O4Purity:98% - 99.59%Color and Shape:LipidMolecular weight:600.47Vitamin D3 Impurity 11
CAS:Formula:C30H50O5Color and Shape:White To Off-White SolidMolecular weight:490.73Fadrozole hydrochloride
CAS:<p>Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.</p>Formula:C14H14ClN3Purity:≥95%Color and Shape:SolidMolecular weight:259.73Enclomiphene citrate
CAS:<p>Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property</p>Formula:C32H36ClNO8Purity:99.95%Color and Shape:SolidMolecular weight:598.08γ-Tocopherol
CAS:<p>(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.</p>Formula:C28H48O2Purity:99.31% - 99.39%Color and Shape:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightMolecular weight:416.68Doxercalciferol
CAS:<p>Doxercalciferol, a synthetic vitamin D2, curbs parathyroid activity for treating secondary hyperparathyroidism and bone disorders.</p>Formula:C28H44O2Purity:99.03% - 99.69%Color and Shape:White Crystalline PowderMolecular weight:412.65Flurandrenolide
CAS:Controlled Product<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formula:C24H33FO6Color and Shape:NeatMolecular weight:436.51O,O-Dimethyl Methylphosphonate
CAS:Controlled Product<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Formula:C3H9O3PColor and Shape:NeatMolecular weight:124.0766a,9a-Difluoroprednisolone 21-Acetate
CAS:Controlled Product<p>Applications 6α,9α-Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.<br>References Toscano L., et al.: J. Med. chem., 20, 213 (1977);<br></p>Formula:C23H28F2O6Color and Shape:White To Off-WhiteMolecular weight:438.467-Ketoabiraterone Acetate
CAS:Controlled Product<p>Applications 7-Ketoabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Formula:C26H31NO3Color and Shape:NeatMolecular weight:405.536-Ethylchenodeoxycholic-d5 Acid
CAS:Controlled Product<p>Applications 6-Ethylchenodeoxycholic-d5 Acid is an isotope labelled compound of 6-Ethylchenodeoxycholic Acid (E899810), which is used in the investigative treatment of primary biliary cholangitis. Primary biliary cholangitis is an autoimmune disease of the liver that slowly progresses to cirrhosis.<br>References Ali, A. H, et al.: Expert Opin. Orphan Drugs, 4, 1011 (2016)<br></p>Formula:C26H39D5O4Color and Shape:NeatMolecular weight:425.66(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione
CAS:Formula:C23H30O5Color and Shape:ColourlessMolecular weight:386.48Betamethasone 17-Butyrate
CAS:Controlled Product<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Formula:C26H35FO6Color and Shape:NeatMolecular weight:462.5511-Deoxy Corticosterone-d7
CAS:Controlled Product<p>Applications Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Formula:C21H23D7O3Color and Shape:White To Off-WhiteMolecular weight:337.55β-Dihydrocortisone Acetate 21-Acetate
CAS:Controlled Product<p>Applications Cortisone (C696500) derivative.<br></p>Formula:C23H32O6Color and Shape:NeatMolecular weight:404.5Ethynyl Estradiol-2,4,16,16-d4
CAS:Controlled Product<p>Applications Isotope labelled Ethynyl Estradiol (E685100), an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.<br></p>Formula:C202H4H20O2Color and Shape:White To Light YellowMolecular weight:300.436β-Hydroxy-21-desacetyl Deflazacort
CAS:<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formula:C23H29NO6Color and Shape:NeatMolecular weight:415.48cis-Diethyl Stilbestrol
CAS:<p>Stability Isomerizes rapidly in Benzene, Chloroform, and Ether.Keep Shielded from light.<br>Applications A synthetic, nonsteroidal estrogen.Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.<br>References White, W. A. et. al.: J. Agric. Food Chem. 19(2), 388-390 (1971).<br></p>Formula:C18H20O2Color and Shape:NeatMolecular weight:268.35Digoxigenin Monodigitoxoside
CAS:Controlled Product<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formula:C29H44O8Color and Shape:BeigeMolecular weight:520.657-Keto Cholesterol
CAS:Controlled Product<p>Applications 7-Keto Cholesterol is a metabolite of Cholesterol.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),<br></p>Formula:C27H44O2Purity:~98%Color and Shape:NeatMolecular weight:400.647b-Fulvestrant
CAS:Controlled Product<p>Impurity Fulvestrant EP Impurity A<br>Applications Fulvestrant (F862500) impurity A. The S-isomer of Fulvestrant.<br>References Sharman, G.J., et al.: Mag. Resonance Chem., 39, 549 (2001),<br></p>Formula:C32H47F5O3SColor and Shape:Light Brown SolidMolecular weight:606.7721-Deacetoxy Deflazacort
CAS:Controlled Product<p>Applications An intermediate of Deflazacort (D228975), a systematic corticosteroid.<br>References Nathansohn, G. et al.: Steroids, 13, 365 (1969); Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980),<br></p>Formula:C23H29NO4Color and Shape:NeatMolecular weight:383.4821-Dehydro Dexamethasone Hydrate
CAS:Formula:C22H27FO5·H2OColor and Shape:White To Light YellowMolecular weight:408.46Difluprednate
CAS:Controlled Product<p>Applications A corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002), Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003), Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005),<br></p>Formula:C27H34F2O7Color and Shape:WhiteMolecular weight:508.55Exemestane
CAS:Controlled Product<p>Applications Exemestane is an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formula:C20H24O2Color and Shape:White To Light GreenMolecular weight:296.40Estradiol 17β-sulfate
CAS:Controlled Product<p>Applications Estradiol 17β-sulfate is a naturally occuring steroid in whihc can be converted into Estradiol(E888000)<br>References Takanashi, K., et al.: Steroids., 68, 383-392 (2003)<br></p>Formula:C18H24O5SPurity:>90%Color and Shape:NeatMolecular weight:352.45∆6-Testosterone
CAS:Controlled Product<p>Impurity Testosterone Decanoate EP Impurity I<br>Applications A metabolite of Testosterone (T155000). Controlled substance.<br>References Peng, S., et al.: Steroids, 67, 39 (2002), Pozo, O., et al.: Drug Metab. Dispos., 37, 2153 (2009),<br></p>Formula:C19H26O2Color and Shape:Beige To Light BrownMolecular weight:286.40Zilpaterol
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications Zilpaterol is a β-Adrenergic agonist. Growth promotant.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004)<br></p>Formula:C14H19N3O2Color and Shape:White To YellowMolecular weight:261.32N,O-Bis(trimethylsilyl)trifluoroacetamide (~90%)
CAS:Controlled Product<p>Applications Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Driscoll, J.S. et al.: J. Med. Chem., 34, 3280 (1991); Pan, L. et al.: J. Pharm. Biomed. Anal., 52, 589 (2010);<br></p>Formula:C8H18F3NOSi2Purity:~90%Color and Shape:Colourless To Light YellowMolecular weight:257.40Estradiol 17-Propionate
CAS:Controlled Product<p>Applications A 17β-estradiol ester as prodrug of Estradiol (E888000).<br>References Kabasakalian, P., et al.: J. Pharm. Sci., 55, 642 (1966), Marsh, M., et al.: Br. Med. Bull., 48, 426 (1992),<br></p>Formula:C21H28O3Color and Shape:White To Off-WhiteMolecular weight:328.456β-Hydroxy Betamethasone
CAS:Controlled Product<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Formula:C22H29FO6Color and Shape:NeatMolecular weight:408.466β-Hydroxy Dutasteride
<p>Applications 6β-Hydroxy Dutasteride is a hydroxylated derivative of Dutasteride (D735000).<br></p>Formula:C27H30F6N2O3Color and Shape:NeatMolecular weight:544.4317β-Carboxy-17α-formyloxy Dexamethasone
CAS:Formula:C22H27FO6Color and Shape:NeatMolecular weight:406.446β-Hydroxycortisone
CAS:<p>Applications 6β-Hydroxycortisone can be used as a probe to detect inhibition of CYP3A4 in vivo.<br>References Peng, C.C., et. al.: Clin. Pharmacol. Ther., 89, 888 (2011)<br></p>Formula:C21H28O6Color and Shape:NeatMolecular weight:376.442-Bromo 17β-Estradiol
CAS:<p>Stability Light Sensitive<br>Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.<br>References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)<br></p>Formula:C18H23BrO2Color and Shape:NeatMolecular weight:351.281,2-Dihydro Exemestane
CAS:Controlled Product<p>Impurity USP Exemestane Related Compound A<br>Applications 1,2-Dihydro Exemestane is a related compound of Exemestane (E957000).<br>References Johannessen, D., et al.: Clin. Cancer Res., 3, 1101 (1997), Kaufmann, M., et al.: J. Clin. Oncol., 18, 1399 (2000), Coombes, R., et al.: Lancet, 369, 559 (2007),<br></p>Formula:C20H26O2Color and Shape:NeatMolecular weight:298.4220(S)-Hydroxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity G<br>Applications 20(S)-Hydroxy Prednisolone (Prednisolone EP Impurity G) is a Prednisolone (P703740) metabolite.<br>References Kim, H., et al.: J. Med. Chem., 30, 2239 (1987), Addison, R., et al.: J. Steroid Biochem., Mol. Biol., 39, 83 (1991),<br></p>Formula:C21H30O5Color and Shape:NeatMolecular weight:362.46Cholesterol
CAS:<p>Applications Cholesterol is a major component of all biological membranes; ~25% of total brain lipid is Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. This compound is a contaminant of emerging concern (CECs).<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Formula:C27H46OColor and Shape:WhiteMolecular weight:386.6511-β,16-α,17-α,21-Tetrahydroxypregna-1,4-diene-3,20-dione
Formula:C21H28O6Color and Shape:NeatMolecular weight:376.445-ANDROSTEN-3,17-DIONE
CAS:Controlled Product<p>Applications 5-Androsten-3,17-dione has been used in the synthetic preparation of androstenediones for treatment of hormone-related disorders.<br>References Davies, H., et al.: U.S. (2011), WO 2011127232 A2<br></p>Formula:C19H26O2Purity:>90%Color and Shape:NeatMolecular weight:286.4116a,17-[(1RS)-Butylidenebis(oxy)]-11b-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity C, Budesonide Impurity C,<br>Applications 16α,17-[(1RS)-butylidenebis(oxy)]-11β-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Budesonide EP Impurity C) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br>References Ferraboschi, P. et al.: J. Pharm. Biomed. Anal., 47, 636 (2008);<br></p>Formula:C25H34O6Color and Shape:WhiteMolecular weight:430.53Spironolactone-d7 (Major)
CAS:Controlled Product<p>Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome. A representative lot was 19% d3; 47% d6; 12% d7; 7% d8; 3% d9; 3% d10 and 8% d11.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),<br></p>Formula:C24H25D7O4SColor and Shape:NeatMolecular weight:423.62Limaprost
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formula:C22H36O5Color and Shape:NeatMolecular weight:380.5217α-Dihydro Equilin
CAS:Controlled Product<p>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formula:C18H22O2Color and Shape:NeatMolecular weight:270.372-Hydroxy Atorvastatin Dihydrate Monosodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formula:C33H38FN2NaO8Color and Shape:NeatMolecular weight:632.654-Methyl Estradiol
CAS:Controlled Product<p>Impurity Estradiol EP Impurity C<br>Applications 4-Methyl Estradiol (Estradiol EP Impurity C) is an impurity of Estradiol (E888000).<br>References Zhu, B., et al.: Steroids, 70, 225 (2005), Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997),<br></p>Formula:C19H26O2Color and Shape:NeatMolecular weight:286.41Spiro[androsta-1,4-diene-6,2'-oxirane]-3,17-dione(Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Exemestane (E957000).<br>References Cavalcanti, G. et al.: Steroids 76, 1010 (2011)<br></p>Formula:C20H24O3Color and Shape:NeatMolecular weight:312.40Betamethasone-d5
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Glucocorticoid.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C22H24D5FO5Color and Shape:Off-White To Light YellowMolecular weight:397.49Formestane
CAS:Controlled Product<p>Applications An antitumor drug. An aromatase inhibitor.<br>References Brodie, A.M. and Njar, V.C.: Steroids, 65, 171 (2000), Lonning, P.E., et al.: J. Steroid Biochem, 77, 39 (2001)<br></p>Formula:C19H26O3Color and Shape:NeatMolecular weight:302.41Isoflupredone-d3 (d2 Major)
CAS:Controlled Product<p>Applications Labelled Isoflupredone (I816600). Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Formula:C21H24D3FO5Color and Shape:NeatMolecular weight:381.45δ 4-Tibolone
CAS:Controlled Product<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Clarkson, T., et al.: J. Clin. Endocrinol. Metab., 86, 5396 (2001), Landgren, M., et al.: Maturitas, 50, 222 (2005), Wang, M., et al.: Steroids, 71, 343 (2006), Verheul, H., et al.: Drug Metab. Dispos., 35, 1105 (2007),<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45(22S)-Budesonide
CAS:Controlled Product<p>Applications Budesonide (B689490) epimer S. Budesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H34O6Color and Shape:NeatMolecular weight:430.53Triamcinolone Hexacetonide
CAS:Controlled Product<p>Applications Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.<br>References Abd-El-Barr, M.M., et al.: J. Ocul. Pharmacol. Ther., 24, 197 (2007); Eberhard, B.A., et al.: J. Rheumatol., 31, 2507 (2004);<br></p>Formula:C30H41FO7Color and Shape:WhiteMolecular weight:532.64S-deacetyl spironolactone
CAS:<p>Applications A metabolite of Spironolactone.<br>References Morris, R., et al.: Eur. J. Clin. Pharmacol., 34, 233 (1988), Dasgupta, A., et al.: Am. J. Clin. Pathol., 111, 406 (1999)<br></p>Formula:C22H30O3SColor and Shape:NeatMolecular weight:374.549-Dehydrotestosterone
CAS:Controlled Product<p>Applications 9-Dehydrotestosterone, is the analogue of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Formula:C19H26O2Color and Shape:NeatMolecular weight:286.41Ciclesonide
CAS:Controlled Product<p>Applications A glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001),<br></p>Formula:C32H44O7Color and Shape:White To Off-WhiteMolecular weight:540.694,5-Dihydro Mometasone Furoate 6-Acetate
Controlled ProductFormula:C29H34Cl2O8Color and Shape:NeatMolecular weight:581.481Finasteride
CAS:Controlled ProductFormula:C23H36N2O2Color and Shape:White To Off-WhiteMolecular weight:372.54(3S,3aS,5aS,6R,9aS,9bS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]dodecahydro-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid
CAS:Controlled ProductFormula:C23H37NO4Color and Shape:NeatMolecular weight:391.5446α-Hydroxy Progesterone (>80%)
CAS:Controlled ProductFormula:C21H30O3Purity:>80%Color and Shape:NeatMolecular weight:330.46Estrone-d4
CAS:Controlled Product<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Formula:C18D4H18O2Color and Shape:White SolidMolecular weight:274.39Mifepristone-d3
CAS:Controlled Product<p>Applications A labelled progesterone receptor antagonist with partial agonist activity. Abortifacient.<br>References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)<br></p>Formula:C29D3H32NO2Color and Shape:Light Yellow SolidMolecular weight:432.61Dydrogesterone-d6 (Major)
CAS:Controlled Product<p>Applications Labelled Dydrogesterone. A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>Formula:C21H22D6O2Color and Shape:NeatMolecular weight:318.48Dienogest-d8 (major)
CAS:Controlled Product<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Formula:C20H17D8NO2Color and Shape:Light YellowMolecular weight:319.47Paricalcitol
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Formula:C27H44O3Color and Shape:NeatMolecular weight:416.64Lasofoxifene
CAS:<p>Applications A next-generation selective estrogen receptor modulator for treating disorders associated with increased bone turnover and osteopenia.<br>References Baumann, R., et al.: Biochem. Pharmacol., 55, 841 (1998), Ammann, P., et al.: Osteoporos Int., 10, 369 (1999), Alexandersen, P., et al.: J. Clin. Endocrinol. Metab., 86, 755 (2001), Bourrin, S., et al.: Bone, 30, 195 (2002), Buzdar, A., et al.: J. Clin. Oncol., 21, 1007 (2003),<br></p>Formula:C28H31NO2Color and Shape:NeatMolecular weight:413.55Betamethasone 11,21-Diacetate
CAS:Controlled Product<p>Impurity Betamethasone Acetate EP Impurity C<br>Applications Betamethasone 11β,21-Diacetate is an impurity of Betamethasone 21-Acetate (B327025); a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003); Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007)<br></p>Formula:C26H33FO7Color and Shape:WhiteMolecular weight:476.5311-Deoxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Formula:C21H28O4Color and Shape:Light BrownMolecular weight:344.445,6-trans-Vitamin D3
CAS:<p>5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol） is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.</p>Formula:C27H44OPurity:98.23%Color and Shape:SolidMolecular weight:384.643α-Hydroxy Tibolone
CAS:Controlled Product<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Formula:C21H30O2Color and Shape:White To Off-WhiteMolecular weight:314.465α-Pregnane-3β,20(S)-diol
CAS:Controlled Product<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Formula:C21H36O2Color and Shape:NeatMolecular weight:320.51Testosterone 17-O-Acetate
CAS:Controlled Product<p>Applications An Androgen.Controlled substance.<br>References Alikhan, A., et al.: J. App. Toxicol., 29, 590 (2009), Christy H., et al.: J. Steroid Biochem. Mol. Biol., 116, 171 (2009), Li, C., et al.: Steroids, 75, 859 (2010),<br></p>Formula:C21H30O3Color and Shape:NeatMolecular weight:330.4617α-Hydroxy Progesterone-d8
CAS:Controlled Product<p>Applications Labelled 17α-Hydroxyprogesterone (H952330). 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C212H8H22O3Color and Shape:Off-WhiteMolecular weight:338.51Equilin 3-Sulfate Sodium Salt (Stabilized with TRIS, 50% w/w)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Equilin 3-Sulfate Sodium Salt, is a metabolite of Equilin (E592800).<br>References Hajdu, A., et al.: Experientia, 27, 956 (1971), Adams, W.P., et al.: J. Pharma. Sci., 68, 986 (1979),<br></p>Formula:C18H19O5S·NaColor and Shape:NeatMolecular weight:370.40trans-Diethyl Stilbestrol
CAS:Controlled Product<p>Stability And Ether., Chloroform, Isomerizes Rapidly In Benzene<br>Applications A synthetic, nonsteroidal estrogen.Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References White, W. A. et. al.: J. Agric. Food Chem. 19(2), 388-390 (1971).<br></p>Formula:C18H20O2Color and Shape:NeatMolecular weight:268.356-β-Hydroxy Eplerenone
CAS:<p>Applications A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br></p>Formula:C24H30O7Color and Shape:White To Off-WhiteMolecular weight:430.49Dydrogesterone
CAS:Controlled Product<p>Applications A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45Spironolactone
CAS:Controlled Product<p>Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),<br></p>Formula:C24H32O4SColor and Shape:Off-WhiteMolecular weight:416.57Eplerenone-d3
CAS:Controlled Product<p>Applications Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formula:C24H27D3O6Color and Shape:NeatMolecular weight:417.51Isoflupredone
CAS:Controlled Product<p>Applications Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Formula:C21H27FO5Color and Shape:NeatMolecular weight:378.435β-Finasteride
CAS:Controlled Product<p>Applications 5β-Finasteride is an azasteroid and 5β-isomeric impurity of Finasteride (F342000).<br>References Cendrowska, I. et al.: J. Liq. Chrom. Rel. Technol., 22, 2259 (1999);<br></p>Formula:C23H36N2O2Color and Shape:Off-WhiteMolecular weight:372.54Medroxy Progesterone-d3
CAS:Controlled Product<p>Applications Labelled Medroxyprogesterone, an orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.<br>References Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007), Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007), Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008), Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008),<br></p>Formula:C22H29D3O3Color and Shape:NeatMolecular weight:347.51Testosterone Enanthate
CAS:Controlled Product<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Formula:C26H40O3Color and Shape:Colourless To Off-WhiteMolecular weight:400.594’-Hydroxy Dutasteride
Controlled Product<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C27H30F6N2O3Color and Shape:NeatMolecular weight:544.53(20S)-21-Hydroxy-20-methylpregn-4-en-3-one
CAS:Controlled Product<p>Applications (20S)-21-Hydroxy-20-methylpregn-4-en-3-one is a side chain degradation product of natural sterols. It is also an intermediate in the preparation of follicular fluid-meiosis activating sterol.<br>References Andor, A. et al.: Appl. Environ. Microbiol., 72, 6554 (2006); Blume, T. et al.: Org, Lett., 5, 1837 (2003);<br></p>Formula:C22H34O2Color and Shape:Off-WhiteMolecular weight:330.56α-Methyl Hydrocortisone 21-Hemisuccinate
CAS:<p>Applications An impurity of Methylhydrocortisone.<br>References Wang, C., et al.: Steroids, 66, 811 (2001),<br></p>Formula:C26H36O8Color and Shape:NeatMolecular weight:476.56Testosterone 17-Valerate
CAS:Controlled Product<p>Applications Testosterone ester. Testosterone 17-Valerate has been a useful compound in the development of immunochemical techniques for detection of anabolic androgenic steroids in food supplements.<br>References Ruelle, P., et al.: Int. J. Pharm., 157, 219 (1997), de la Torre, X., et al.: J. Pharm. Biomed. Anal., 24, 645 (2001), Adat, S., et al.: Lett. Drug Des. Discov., 1, 334 (2004), Holubova, B., et al.: Eur. Food Res. Technol., 245, 1011 (2019)<br></p>Formula:C24H36O3Color and Shape:NeatMolecular weight:372.541Estriol
CAS:Controlled Product<p>Applications A metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Formula:C18H24O3Color and Shape:White To Off-WhiteMolecular weight:288.3825-Hydroxy Vitamin D3 3-Sulfate Sodium Salt (90%)
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 (C125700).<br>References Higashi, T. et al.: Steroids, 65, 281 (2000); Higashi, T. et al.: Ann. Clin. Biochem., 36, 43 (1999);<br></p>Formula:C27H43NaO5SPurity:90%Color and Shape:NeatMolecular weight:502.6820,21-Dehydro Spironolactone
CAS:Controlled ProductFormula:C24H30O4SColor and Shape:NeatMolecular weight:414.56Androstane Spin Label (ASL)
CAS:Controlled Product<p>Applications Androstane Spin Label (ASL) is a spin labelled Androstane used to mimic Androstane.<br>References Scheidt, H., et al.: J. Biol. Chem., 278, 45563 (2003);<br></p>Formula:C23H38NO3Color and Shape:NeatMolecular weight:376.55Trilostane
CAS:Controlled Product<p>Applications An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.<br>References Komanicky, P., et al.: J. Clin. Endocrinol. Metab., 47, 1042 (1978), Mori, Y., et al., Chem. Pharm. Bull., 29, 2646 (1981), Williams, C.J., et al.: Cancer Treat. Rep., 71, 1197 (1987)<br></p>Formula:C20H27NO3Color and Shape:WhiteMolecular weight:329.43Sodium Pregnenolone-17α,21,21,21-d4 Sulfate
CAS:Controlled Product<p>Applications Sodium Pregnenolone-17alpha,21,21,21-d4 Sulfate (CAS# 1485492-21-4) is a useful isotopically labeled research compound.<br></p>Formula:C21H27D4NaO5SColor and Shape:NeatMolecular weight:422.5517β-Estradiol-d3 17-Acetate 3-β-D-Glucuronide
Controlled Product<p>Applications A labelled Estradiol (E888000) derivative.<br></p>Formula:C26H31D3O9Color and Shape:NeatMolecular weight:493.5611-Dehydrodexamethasone
CAS:Controlled ProductFormula:C22H27FO5Color and Shape:NeatMolecular weight:390.4452Zilpaterol-d7
CAS:Controlled Product<p>Applications b-Adrenergic agonist. Zipaterol, is used to promote growth. Zilpaterol is used to increase the size of cattle.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004),<br></p>Formula:C14H12D7N3O2Color and Shape:Light BrownMolecular weight:268.36Isoflupredone Acetate
CAS:Controlled Product<p>Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.<br>References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);<br></p>Formula:C23H29FO6Color and Shape:Off-WhiteMolecular weight:420.47Fluorometholone
CAS:Controlled Product<p>Applications Fluorometholone is a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formula:C22H29FO4Color and Shape:White To Off-WhiteMolecular weight:376.464-Hydroxy Atorvastatin Hemicalcium Salt
CAS:<p>Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);<br></p>Formula:C66H68CaF2N4O12Purity:>90%Color and Shape:NeatMolecular weight:1187.34Testosterone-d3 β-D-Glucuronide Monosodium Salt
CAS:Controlled Product<p>Applications Labelled Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug<br></p>Formula:C25H32D3NaO8Color and Shape:Off-WhiteMolecular weight:489.55Desonide 21-Acetate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Desonide 21-Acetate is a reactant in the synthesis of 7α-halogenocorticosteroids with anti-inflammatory activity.<br>References De, K., et. al.: J. Indian Chem. Soc., 79, 513 (2002)<br></p>Formula:C26H34O7Color and Shape:NeatMolecular weight:458.54Promestriene
CAS:Controlled Product<p>Applications A synthetic diethyl-ether of Estradiol with no distal hormonal effects, in patients undergoing surgical correction for stress urinary incontinence (SUI).<br>References Kelleher, C., et al.: Br. J. Obstet. Gynaecol., 104, 1374 (1997), Deffieux, X., et al.: J. Gynecol. Obstet. Biol. Reprod., 35, 678 (2006),<br></p>Formula:C22H32O2Color and Shape:NeatMolecular weight:328.49trans-Doxercalciferol
CAS:Controlled Product<p>Applications A Vitamin D derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koeffler, M.R., et al.: Blood, 74, 82 (1989),<br></p>Formula:C28H44O2Color and Shape:NeatMolecular weight:412.654-Hydroxy Estradiol 1-N7-Guanine
CAS:Controlled Product<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H27N5O4Color and Shape:NeatMolecular weight:437.4916α-Methyl-11-oxo Prednisolone
CAS:Controlled Product<p>Applications A 16α-substituted Prednisolone as potent topical antiinflammatory agent.<br>References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),<br></p>Formula:C22H28O5Color and Shape:White SolidMolecular weight:372.45Ospemifene
CAS:Controlled Product<p>Applications Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formula:C24H23ClO2Color and Shape:White To Off-WhiteMolecular weight:378.89δ-5(6)-Norethindrone Acetate
CAS:Controlled Product<p>Impurity Norethindrone Acetate EP Impurity C<br>Applications Δ-5(6)-Norethindrone Acetate (Norethindrone Acetate EP Impurity C) is an impurity of Norethindrone Acetate (N675990).<br></p>Formula:C22H28O3Color and Shape:NeatMolecular weight:340.46Estrone 3-Acetate
CAS:Controlled ProductFormula:C20H24O3Color and Shape:White To Off-WhiteMolecular weight:312.404-Hydroxy Ospemifene (Ospemifene Impurity)
CAS:<p>Applications 4-Hydroxy Ospemifene is an Ospemifene (O703000) impurity, used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formula:C24H23ClO3Color and Shape:NeatMolecular weight:394.89Prednisolone Caproate
CAS:Controlled ProductFormula:C27H38O6Color and Shape:NeatMolecular weight:458.59Desmosterol-d6
CAS:Controlled Product<p>Applications A labelled metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formula:C272H6H38OColor and Shape:NeatMolecular weight:390.67(2α)-Methyl Megestrol Acetate
CAS:Controlled Product<p>Impurity Megestrol Acetate EP Impurity H<br>Applications (2α)-Methyl Megestrol Acetate (Megestrol Acetate EP Impurity H) is a related impurity in Megestrol acetate (M208050).<br>References Schneider, F., et al.: Helv. Chim. Acta, 56, 2396 (1973), Aisner, J., et al.: Semin. Oncol., 15, 68 (1988), Krischenowski, D., et al.: Steroids, 58, 278 (1993), Bratoeff, E., et al.: Chem. Pharm. Bull., 51, 1132 (2003),<br></p>Formula:C25H34O4Color and Shape:NeatMolecular weight:398.54Digitoxin
CAS:<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Formula:C41H64O13Color and Shape:White To Off-WhiteMolecular weight:764.94(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Formula:C22H28O5Color and Shape:White To Light RedMolecular weight:372.45Testosterone 17-Isobutyrate
CAS:Controlled Product<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Formula:C23H34O3Color and Shape:Off-WhiteMolecular weight:358.514-Pregnen-17α, 20α-diol-3-one
CAS:Controlled ProductFormula:C21H32O3Color and Shape:NeatMolecular weight:332.48Finasteride Carboxylic Acid Methyl Ester
CAS:Controlled Product<p>Applications Finasteride Carboxylic Acid Methyl Ester is an metabolite of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993), Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997), McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998),<br></p>Formula:C24H36N2O4Color and Shape:NeatMolecular weight:416.554Progesterone
CAS:Controlled Product<p>Applications Steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.This compound is a contaminant of emerging concern (CECs).<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H30O2Color and Shape:WhiteMolecular weight:314.46BGP 15
CAS:Controlled Product<p>Applications BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.<br>References (1) Berkovich, L., et al.: Anticancer Drugs. 21, 609 (2010) (2) Szabados, E., et al. Biochem Pharmacol. 59, 937 (2000)<br></p>Formula:C14H22N4O2·2HClColor and Shape:NeatMolecular weight:351.272-Hydroxy-17β-estradiol
CAS:<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formula:C18H24O3Color and Shape:Light Yellow To Dark YellowMolecular weight:288.38Bisnorcholenaldehyde
CAS:Controlled Product<p>Applications Bisnorcholenaldehyde can be used to prepare 27-Nor-Δ4-dafachronic acid as a synthetic ligand of Caenorhabditis elegans DAF-12 receptor. It is also used to synthesize 3β,6α-dihydroxy-5α-cholan-23-one.<br>References Samaja, G., et al.: Bioorg. Med. Chem. Lett., 23, 2893 (2013); Nahar, L., et al.: Tetrahedron, 59, 8623 (2003)<br></p>Formula:C22H32O2Color and Shape:NeatMolecular weight:328.49Finasteride-d9
CAS:Controlled ProductFormula:C232H9H27N2O2Color and Shape:NeatMolecular weight:381.60Gestodene
CAS:Controlled Product<p>Applications Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981), Duesterberg, B., et al.: Seroids, 43, 43 (1984), Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985),<br></p>Formula:C21H26O2Color and Shape:NeatMolecular weight:310.43Ruscogenin
CAS:<p>Applications A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.<br>References Huang, Y. et al.: Drug Dev. Res., 69, 196 (2008); Huang, Y. et al.: J. Pharmacol. Sci., 108, 198 (2008); Song, J. et al.: J. Pharmacol. Sci., 113, 409 (2010);<br></p>Formula:C27H42O4Color and Shape:NeatMolecular weight:430.62Tetrahydrodehydrocorticosterone
CAS:Controlled Product<p>Applications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.<br>References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)<br></p>Formula:C21H32O4Color and Shape:NeatMolecular weight:348.482-Hydroxy Estrone
CAS:Controlled ProductFormula:C18H22O3Color and Shape:Off-White To Light BrownMolecular weight:286.37Cortisol 21-Sulfate Potassium Salt
CAS:Controlled Product<p>Applications Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Formula:C21H29KO8SColor and Shape:NeatMolecular weight:480.61δ7-Avenasterol (E/Z mixture)
CAS:<p>Applications Δ7-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>Formula:C29H48OColor and Shape:White To Off-WhiteMolecular weight:412.69Dutasteride
CAS:Controlled Product<p>Applications Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H30F6N2O2Color and Shape:NeatMolecular weight:528.53Eplerenone Hydroxyacid Potassium Salt
CAS:Controlled Product<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Formula:C24H31O7·KColor and Shape:Off-White To Light YellowMolecular weight:470.60Desogestrel-13C2,d2 (Major)
CAS:Controlled Product<p>Applications A labelled progestogen with low androgenic potency.<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formula:C2013C2H28D2OColor and Shape:NeatMolecular weight:314.4717-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid
Controlled Product<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Formula:C20H24O5Color and Shape:NeatMolecular weight:344.4010β-Peroxy ∆4-Tibolone
CAS:Controlled Product<p>Applications ∆4-Tibolone derivative. A potential impurity of ∆4-Tibolone (T437505).<br>References Grunwell, J.F., et al.: Steroids, 27, 759 (1976),<br></p>Formula:C21H28O4Color and Shape:NeatMolecular weight:344.44E,E-Dienestrol
CAS:Controlled Product<p>Applications A metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Formula:C18H18O2Color and Shape:NeatMolecular weight:266.3317-Hydroxy Pregnenolone
CAS:Controlled Product<p>Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Formula:C21H32O3Color and Shape:White To Off-WhiteMolecular weight:332.48Fulvestrant 3-β-D-Glucuronide
CAS:Controlled Product<p>Applications A metabolite of Fulvestrant (F862500).<br>References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),<br></p>Formula:C38H55F5O9SColor and Shape:Off-White To Light BeigeMolecular weight:782.89
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