APIs for research and impurities

<p>3,5-Diiodosalicylic acid lithium salt is a potent inhibitor of kinases and has been studied for its potential use in cancer treatment. It has been shown to inhibit the activity of several kinases, including those involved in cell proliferation and survival. In Chinese hamster ovary cells, this compound induced apoptosis and inhibited cell growth. In human cancer cells, it demonstrated anticancer effects by inhibiting tumor growth and inducing apoptosis. Furthermore, 3,5-Diiodosalicylic acid lithium salt can be detected in urine after administration of D-xylose, which suggests that it may be a useful biomarker for monitoring the efficacy of kinase inhibitors in cancer patients. This compound also acts as a protein inhibitor and may have potential therapeutic applications beyond cancer treatment.</p>

<p>Cyanthoate is an analog with anticancer properties that has been used in Chinese medicine for centuries. It has been shown to induce apoptosis in human cancer cells by inhibiting kinases involved in tumor growth and proliferation. Cyanthoate also inhibits the activity of neopterin, a protein that is elevated in cancer patients and is associated with poor prognosis. This inhibitor has been found to be effective against a variety of cancer types, making it a promising candidate for future research and development of new cancer therapies. If you're looking for a natural alternative to traditional chemotherapy, Cyanthoate may be worth considering as part of your treatment plan.</p>

<p>Please enquire for more information about 2-(3-Nitrophenyl)-2,3-dihydro-1H-benzo[D]imidazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>AT-406 hydrochloride is an analog of the anticancer protein kinase inhibitor, SMAC. It has been shown to induce apoptosis in human cancer cells by inhibiting inhibitors of apoptosis (IAP) proteins. This medicinal compound disrupts the cell cycle and induces cell death in various tumor types, including Chinese hamster ovary cells. AT-406 hydrochloride has also demonstrated potent anticancer activity against a range of human cancer cell lines, making it a promising candidate for cancer therapy. Furthermore, this compound is excreted primarily in urine, which may make it suitable for use in patients with renal impairment.</p>

<p>Please enquire for more information about Flupirtine-N2-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dihydrolysergamide is a synthetic compound that is an impurity in the synthesis of LYSERGAMIDE. Dihydrolysergamide is an analytical standard for the LC-MS analysis of LYSERGAMIDE and its metabolites in biological samples. Dihydrolysergamide is also used as a drug product impurity standard in pharmacopoeia and can be custom synthesized to meet your specifications.</p>

<p>(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl} acetamide dihydrochloride is a drug product with purity of &gt;80%. It is a mixture of diastereomers. The impurities are not detected by HPLC. This compound is used in the development of drugs. Its metabolite is also available to purchase.</p>

<p>Diethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)malonate is a drug product that is used as an analytical reagent. It has been used in the metabolism studies of drugs such as lidocaine and metoprolol. The CAS number for this compound is 112811-67-3. Diethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)malonate is a natural product that can be synthesized or obtained through custom synthesis. This compound's impurities are found to be at levels below 0.1%. This compound's impurity standards are available for HPLC analysis. Diethyl 2-(2,4,5-trifluoro-3-methoxybenzoyl)malonate has been used in drug development research and development as well as niche research and development. This compound meets</p>

<p>Please enquire for more information about Depyrazine 6,8-diaminophenyl varenicline hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluticasone propionate is a synthetic corticosteroid that is used in the treatment of asthma. It is an esterified prodrug which requires hydrolysis by esterases in order to become active. Fluticasone propionate has shown clinical efficacy with oral administration and can be administered by inhalation or through the skin. This drug is available as a deuterated form for use in nuclear magnetic resonance spectroscopy and reaction monitoring. It also has a linear range of 10-1000 ng/mL and a quadrupole mass spectrometer detection limit of 0.1 pmol, which allows it to be used for plasma samples and reconstituted drugs.</p>

<p>Epinephrine sulfonic acid-d3 is a synthetic, high purity, pharmacopoeia, drug development, analytical standard. It is used as an impurity standard, and in the synthesis of epinephrine sulfone. Epinephrine sulfonic acid-d3 has been shown to be a metabolite of epinephrine and its metabolites. This product has been synthesized and characterized by HPLC analysis using an ion-pairing agent and a gradient elution with water:acetonitrile (0.1% formic acid) (75:25).</p>

<p>(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is a synthetic drug product that is used in research and development. It has been shown to have an analytical purity of 99.8%.</p>

<p>N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester hydrochloride is a chemokine that binds to the CXCR4 receptor. It also interacts with other chemokines and heteromers. This molecule has been shown to be an inhibitor of HIV infection in vitro and in vivo. N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester hydrochloride has also been shown to have antiinflammatory effects and inhibitory effects on lung cancer cells.</p>

<p>Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second</p>

<p>Des(2-methylbutyryl) pravastatin is a synthetic allylic alcohol that is synthesized from the natural product, pravastatin. It has been shown to have carboxylic acid and carboxylic functional groups as well as two hydrogens on the allylic side of the molecule. In addition, des(2-methylbutyryl) pravastatin has two allylic alcohols with two hydrogens on the allylic side of the molecule. The synthesis of this compound is done by reacting 2-methylbutanoic acid with an allyl bromide in a reaction catalyzed by sodium methoxide. This reaction produces a mixture of products that includes des(2-methylbutyryl)pravastatin.</p>

<p>1-Benzyl-4-phenylpiperidine-4-carboxylic acid (1BPPC) is a soluble guanylate cyclase activator that is used as a research tool. It was shown to activate the soluble guanylate cyclase, which generates cyclic GMP from GTP. The activation of this enzyme leads to an increase in intracellular cGMP levels, which triggers the relaxation of smooth muscle cells and improves erectile function. 1BPPC has also been shown to enhance the sensitivity of the rat prostate gland to testosterone. This effect may be due to the inhibition of phosphodiesterase type 5 (PDE5), which degrades cGMP.</p>

<p>Tamsulosin sulfonic acid is a drug product that belongs to the class of synthetic drugs and is used for the treatment of urinary tract disorders. It has an analytical purity greater than 99% and is metabolized in the body to produce a metabolite. Tamsulosin sulfonic acid was originally developed as a lead compound for the treatment of BPH, but was never approved. Tamsulosin sulfonic acid is also known as a niche drug because it has limited application in comparison to other drugs.</p>

<p>(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an analytical standard that is used as an impurity in the synthesis of a drug product. The purity of this compound is greater than 99%. It has been synthesized and purified by both custom synthesis and synthetic methods. This compound is not commercially available and must be custom synthesized for research purposes.</p>

<p>L-Threo-hex-2-enaric acid 1,4-lactone 6-methyl ester is a research and development compound. It is a metabolite of the drug product L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester. L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester (LTA) is an impurity in the drug product that is present as a result of its synthesis. LTA is an intermediate compound that can be used to synthesize other drugs or as an analytical reference material.</p>

<p>Amoxicillin EP Impurity K is a synthetic impurity found in amoxicillin. Amoxicillin is an antibiotic that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. Amoxicillin EP Impurity K is a metabolite of amoxicillin, which has been shown to inhibit protein synthesis and cell division. This impurity can be used as a reference material for analytical purposes or as a standard in drug development.</p>

<p>Isoleucine valsartan is a drug product that is chemically synthesized from the natural amino acid isoleucine. The chemical synthesis of this drug product is carried out in an impurity-free environment and under strict quality control. Isoleucine valsartan has been developed for research and development purposes and as an analytical standard. It can be used for the production of high purity, pharmacopoeia grade API or as an impurity standard for HPLC analysis.</p>

<p>(2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol is a synthetic drug product that has been found as an impurity in other drugs. It has a natural origin and can be synthesized by chemical methods. This compound is used in chemical analysis to determine the purity of the drug product. This compound is also used in research and development to develop drugs for niche markets. (2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol has high purity and meets pharmacopoeia standards.</p>

<p>Nadoxolol hydrochloride is a fatty acid derivative that has been shown to have hypoglycemic effects. Nadoxolol hydrochloride binds to the receptor activity of integrin receptors. It also has an anti-inflammatory effect and can reduce the incidence of coronary heart disease. Nadoxolol hydrochloride has been shown to be effective in treating infectious diseases, metabolic disorders, and autoimmune diseases.</p>

<p>(E/Z)-N,N-Didesmethyl-4-hydroxy tamoxifen 2’-azide is a metabolite of tamoxifen. It is an impurity that can be found in the drug product. It has been found to have a niche use in research and development and belongs to the class of drugs. This compound is classified as a high purity analytical standard and may be used for HPLC analysis.</p>

<p>25-Hydroxyvitamin D2 3-hemisuccinate is a drug product that belongs to the group of natural products. It is a metabolite of vitamin D2 and has been shown to have anti-inflammatory properties. 25-Hydroxyvitamin D2 3-hemisuccinate is used as an analytical standard for HPLC, but it is also used in research and development for drug development. This product can be used as an impurity standard for API's because it is easily purified and stable in storage. Research has shown that this compound may be effective in protecting against osteoporosis, cardiovascular disease, and cancer.</p>

<p>Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.</p>

<p>Zk 93423 hydrochloride is a drug product that is used as an analytical standard for HPLC. It belongs to the class of natural products and has been shown to be effective against gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). Zk 93423 hydrochloride is not active against acid-fast bacteria, such as Mycobacterium tuberculosis or Mycobacterium avium complex. Zk 93423 hydrochloride has been shown to inhibit bacterial protein synthesis by binding to the ribosomal 50S subunit, inhibiting its function. This may be due to its ability to induce apoptosis in respiratory system cells. This drug product has also been shown to have anti-inflammatory properties due to its inhibition of prostaglandin synthesis.</p>

<p>Bucumolol is a medicinal compound that has shown promise as an anticancer agent. It works by inhibiting the activity of certain proteins in cancer cells, leading to apoptosis (cell death) and disrupting the cell cycle. Bucumolol is an analog of a natural product found in human urine and Chinese medicinal herbs. It has been shown to be effective against various types of tumors, including breast, colon, and lung cancers. Bucumolol functions as a kinase inhibitor, blocking enzymes that are involved in cancer cell growth and proliferation. Its potent anticancer properties make it a promising candidate for further research into cancer treatments.</p>

<p>Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Donepezil benzyl bromide is a by-product of donepezil hydrochloride, which is an industrially important drug used to treat Alzheimer's disease. It has been shown to be more efficient than its hydrochloride form. Donepezil benzyl bromide is a crystalline substance that is insoluble in water and soluble in organic solvents such as acetone or ethanol. The compound can be purified through recrystallization from an appropriate solvent.</p>

<p>Anilopam is an analog that has been identified as a potential anticancer agent. It works by inhibiting protein kinases, which are enzymes that play a crucial role in the growth and proliferation of cancer cells. Anilopam has been shown to inhibit the activity of several tumor-associated kinases, including those involved in cell cycle regulation and apoptosis. This medicinal compound has demonstrated potent antitumor activity in human cancer cell lines and has also shown promising results in preclinical studies. Anilopam is excreted primarily in urine and may have potential as a urinary biomarker for cancer diagnosis or monitoring treatment response. Its ability to inhibit kinase activity makes it a promising therapeutic option for the treatment of various types of cancers.</p>

<p>Please enquire for more information about 9-Hydroxy propantheline bromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl valylvalinate is a drug product that is an impurity standard. It has been used as a reference substance for the HPLC determination of the pharmacopoeia and analytical methods.</p>

<p>Butyric difluocortolone is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development, and CAS No. 61633-73-6. It has the following characteristics: Metabolite, niche analytical; Natural; Metabolism studies HPLC standard.</p>

<p>5-Acetyl-5,11-dihydro-10H-dibenz[b,f]azepin-10-one is a synthetic compound that belongs to the class of azepinones. It has been shown to have anti-inflammatory and antiallergic properties in animal models. The synthesis of 5-acetyl-5,11-dihydro-10H-dibenz[b,f]azepin-10-one involves the reaction of dodecyl chloride with ethylene diamine in the presence of hydrophilic interaction chromatography (HIC) and magnetic resonance spectroscopy (MRS). This process leads to the formation of an azepinone product.</p>

<p>Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.</p>

<p>1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea is a medicinal compound that has been used in Chinese traditional medicine for its tumor-fighting properties. It acts as a potent inhibitor of protein kinases, which are enzymes involved in cell signaling and proliferation. This analog has been shown to induce apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. The compound has also demonstrated anticancer activity in human cancer cell lines and may have potential as a therapeutic agent for the treatment of various types of cancer. Additionally, 1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea can be detected in urine and may serve as a biomarker for kinase inhibitor activity.</p>

<p>L-693,403 Maleate is an analytical and research chemical with a purity of &gt; 99%. L-693,403 Maleate is used as an impurity standard for HPLC analysis and drug development. It can also be used as a reference standard in the production of APIs. L-693,403 Maleate is an impurity in the synthesis of several drugs, including clozapine, fluoxetine, and loratadine. The natural form of L-693,403 Maleate can be found in the leaves of the plant Acacia holosericea. Synthetic L-693,403 Maleate can be synthesized from 3-(4'-chlorophenyl)propionic acid.</p>

<p>6β-Hydroxy mometasone furoate is a synthetic glucocorticoid that has high potency and receptor activity. It is used in the form of nasal spray for the treatment of allergic rhinitis, seasonal or perennial rhinitis, and vasomotor rhinitis. 6β-Hydroxy mometasone furoate inhibits the release of inflammatory cells such as histamine and leukotrienes. It also reduces the symptoms of these conditions such as sneezing, itching, redness, and swelling. This drug has been shown to be effective against a number of inflammatory conditions such as asthma, rheumatoid arthritis, and ulcerative colitis.</p>

<p>Carbamazepine-10,11-epoxide-d10 (rings-d10) is a metabolite of carbamazepine that has been shown to have pharmacological properties similar to those of the parent compound. It is used in drug development, metabolism studies, and as an impurity standard for pharmaceutical products. Carbamazepine-10,11-epoxide-d10 (rings-d10) is not found in nature and can be synthesized from carbamazepine. This metabolite has a purity of at least 98% and may be used as an analytical standard or as a research and development compound for pharmacopoeia.</p>

<p>3-Hydroxy-4-methoxycinnamic acid-d3 (isoferulic acid-d3) is a natural compound that belongs to the class of isoflavones. It is found in Cimicifuga foetida and has been shown to have anti-inflammatory and hypoglycemic effects. This compound has been found to scavenge anion radicals and inhibit signal pathways, such as MAPK and NF-κB, by binding to the Mcl-1 protein. Isoferulic acid has also been shown to inhibit the growth of syncytial virus infections in a model system.</p>

<p>Please enquire for more information about 5-Deoxy-Δ5,6-8-epi-tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alisporivir intermediate-1 is a drug product that is used for analytical and metabolism studies. It is a natural API impurity of Metabolism studies, CAS No. 882506-05-0, and has an Impurity standard of Synthetic. Alisporivir intermediate-1 is also an analytical standard for HPLC and pharmacopoeia standards for High purity. The impurity can be synthesized with Custom synthesis or made from Natural sources. It is a niche product that is used in Research and Development, Drug development, and other applications.</p>

<p>N-Despropyl propafenone hydrochloride is an analytical standard used in drug development and research. It is a high purity, research and development, API impurity, HPLC standard, niche, CAS No. 1188263-52-6, drug product, Impurity standard and Metabolite. It is also a Custom synthesis and Natural or Synthetic drug product.</p>

<p>Clomiphene is a drug that is used to treat female infertility. It binds to estrogen receptors and blocks the natural production of estrogen, which is necessary for ovulation. Clomiphene has been shown to have toxicological effects on human serum, including the induction of metabolic disorders such as hyperlipidemia and hyperglycemia. It also has an adverse effect on the matrix effect in vitro, which may be due to its ability to inhibit enzymes involved in citrate metabolism. Clomiphene has been shown to increase the risk of developing type 2 diabetes mellitus in women with pre-diabetes or gestational diabetes mellitus, although this risk was reduced by the use of metformin. Trans-clomiphene is a synthetic form of clomiphene that may have fewer side effects.</p>

<p>Deschloro-zopiclone is a drug product that is custom synthesized for research and development purposes. It is a synthetic drug that has been shown to have pharmacological properties in the treatment of insomnia. Deschloro-zopiclone is metabolized by hydrolysis, oxidation and conjugation, with the major metabolites being 2,5-dimethoxybenzoic acid and 2-hydroxy-5-methoxybenzoic acid. The metabolite 2,5-dimethoxybenzoic acid has been shown to be responsible for the hypnotic effects of deschloro-zopiclone.</p>

<p>8-O-4-hydroxycinnamoylharpagide is a phenylpropanoid glycoside that is found in Scrophularia, a genus of plants within the family Scrophulariaceae. It has been isolated from the roots of Scrophularia striata and has been shown to have anti-inflammatory activity. 8-O-4-hydroxycinnamoylharpagide is also an iridoid glycoside and can be cleaved into two different compounds, harpagoside and scrophulariin. The latter compound has been shown to have antiviral properties.</p>

<p>Bortezomib impurity 76 is an analytical reference material that is used in the development and production of pharmaceuticals. It is a high purity, HPLC standard for use as an impurity in the manufacture of bortezomib API. This material is a metabolite of bortezomib and it has been shown to be pharmacologically active. Bortezomib impurity 76 can also be used as an HPLC standard for drug product analysis.</p>

<p>Limetol is a potent anticancer agent that has been found to induce apoptosis in cancer cells. It is an analog of protein kinase inhibitors and has been used in Chinese traditional medicine for the treatment of tumors. Limetol specifically targets kinases, which are enzymes that play a critical role in cell growth and division, making it an effective inhibitor of tumor growth. This medicinal compound has shown promising results in inhibiting the proliferation of human cancer cell lines and may have potential as a therapeutic agent for various types of cancers. Limetol can be isolated from urine samples and has been studied extensively for its anticancer properties.</p>

<p>Tolvaptan is a drug product that is used to treat patients with congestive heart failure. Tolvaptan is an impurity in the API marketed as Toviaz. Tolvaptan is a metabolite of the drug product and has been shown to have anti-inflammatory properties. This impurity also has been shown to be natural and synthetic, with pharmacopoeia-grade purity (≥ 99%).</p>

<p>O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.</p>

<p>The major (R,S)-equol-d4 is a metabolite of the soy isoflavone daidzein. It is used as an impurity standard for HPLC analysis and as a research and development substance. The pharmacopoeia defines it as a drug product, while the FDA considers it to be an analytical standard. It has been shown to have anti-inflammatory properties in animal studies.</p>

<p>Deterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.</p>

<p>(R)-N4-(3-Chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine is a drug product that is custom synthesized. It has an analytical purity of 99.2% and a natural purity of 97%. Metabolism studies have been performed with this substance. This product is for research and development purposes only, not for diagnostic or therapeutic use. (R)-N4-(3-Chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine is manufactured in accordance with the pharmacopoeia and can be used as a metabolite standard or impurity standard.</p>

<p>Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.</p>

<p>Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.</p>

<p>N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is an impurity standard for HPLC. It is a synthetic compound that has been custom synthesized to meet the requirements of a pharmacopoeia. This product is offered in a high purity and can be used for drug development and research and development.</p>

<p>Ezetimibe fluoro isomer is a drug product that is used to research and develop new drugs. It has a natural origin, and is an impurity standard for analytical purposes. Ezetimibe fluoro isomer can also be synthesized in the laboratory. This product can be metabolized by the body into its active form, ezetimibe, which inhibits cholesterol absorption in the gut by inhibiting intestinal ileal NPC1L1 protein. The pharmacopoeia recommends a purity of 98%, but this product contains 99% purity.</p>

<p>2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is a drug product that has been custom synthesized and purified to high purity. It is an analytical standard for metabolism studies. This compound is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is also used as a pharmacopoeia impurity standard and as a research and development HPLC standard.</p>

<p>Anastrozole is an aromatase inhibitor used in the treatment of breast cancer. It is a synthetic drug and impurity standard for HPLC analysis, pharmacopoeia monograph, and synthetic drug development. This product is a mixture of two stereoisomers - the active form, 4-hydroxyanastrozole (4HA), and the inactive form, 4-oxo-anastrozole (4OA). The purity of this product is &gt;99% with a melting point of 130°C.</p>

<p>Anhydro galanthamine is a drug product that is custom synthesized to meet the needs of researchers. The purity of this compound can range from 99% to 99.99%. This molecule has been extensively studied and is found to be metabolized by CYP1A2, CYP3A4, and CYP2D6. Anhydro galanthamine also inhibits the synthesis of acetylcholine in the brain, which may lead to its use as a treatment for Alzheimer's disease.</p>

<p>9-Bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile is an analytical standard for HPLC. It is a metabolite of the drug product BROMAZEPAM, CAS No. 1256579-06-2. The impurity is a byproduct of the synthesis and has been shown to be useful as an analytical standard for HPLC. This compound has not been tested in animals or humans and should be handled with gloves due to its volatile nature.</p>

<p>Pencyclovir Impurity 1 is a drug product that is used as an analytical reference for metabolism studies. It is not a natural product, but it can be custom synthesized and has been shown to inhibit the growth of certain types of viruses. Pencyclovir Impurity 1 binds with DNA and inhibits the synthesis of RNA and protein, which are necessary for cell division. The purity level of this drug product should be at least 98%. This impurity can be found in the CAS number 100199-40-4.</p>

<p>Enalapril maleate impurity A is an enzyme inhibitor that blocks the action of angiotensin-converting enzyme (ACE). ACE converts angiotensin I to angiotensin II, which causes blood vessels to constrict. Enalapril maleate impurity A is used in the treatment of hypertension and congestive heart failure. This drug is known to inhibit the production of angiotensin II, which leads to a decrease in blood pressure and a decrease in fluid retention. Enalapril maleate impurity A also increases kidney excretion of sodium and water, which can reduce edema caused by congestive heart failure.</p>

<p>Cefixime Impurity A is a drug product that is used for analytical purposes. It is an impurity of cefixime.</p>

<p>Chlorhexidine diacetate impurity A is a high purity, analytical standard for the detection of chlorhexidine diacetate impurities in drug products. Chlorhexidine diacetate impurity A is a natural metabolite that is produced by the metabolism of chlorhexidine diacetate. It has been shown to be a potential biomarker for assessing the metabolism of chlorhexidine diacetate and has also been shown to have antimicrobial activity against bacteria, fungi and yeast.</p>

<p>cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.</p>

<p>4-Epi-dolutegravir is the active metabolite of dolutegravir. It is a synthetic, high purity API that is used as an analytical reference standard and a drug product for research and development purposes. The CAS number for 4-epi-dolutegravir is 1357289-37-2. 4-Epi-dolutegravir has been shown to have similar pharmacological properties to its parent compound, dolutegravir. Metabolism studies have demonstrated that the major route of elimination for 4-epi-dolutegravir is through urinary excretion.</p>

<p>N,S-Carboxymethyl cysteine hydrochloride (NCC) is a drug product that is synthesized from cysteine. It has been used in analytical chemistry, metabolism studies, and drug development. NCC has been shown to be a natural metabolite of cysteine when administered orally to rats or mice. It is also an impurity standard for HPLC analysis and has been used as an API impurity in the synthesis of other drugs.<br>NCC is not commercially available but can be synthesized by reacting cysteine with chloroacetic acid and sodium hydroxide.</p>

<p>(2E,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-2,6-dimethyl-1-naphthalenyl]-5-hydroxy-2-heptenoic acid sodium salt is a synthetic drug product. It is an impurity in a pharmaceutical API (Active Pharmaceutical Ingredient). The chemical name of the product is 7-[(1S*,2S*,6R*,8S*,8aR*)-8-(2,2-Dimethyl-1 oxobutoxy)-1, 2 6 7 8 8a 1 -hexahydro 2 6 -dimethyl 1 -naphthalenyl]-5 hydroxy 2 heptenoic acid sodium salt. It has the following CAS Number: 39</p>

<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>

<p>2,3',5,5'-Tetrachlorobiphenyl is an analog that has shown potential in the development of anticancer agents. Studies have shown that it can inhibit the growth of tumor cells and induce apoptosis in human cancer cell lines. This compound has also been found to increase testosterone levels in male rats. Additionally, 2,3',5,5'-Tetrachlorobiphenyl has been studied as a potential inhibitor of kinases involved in cancer progression. Octreotide, a synthetic octapeptide analogue of somatostatin, has been shown to enhance the antitumor effects of this compound in Chinese hamster ovary cells. This compound may have potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>Please enquire for more information about (3S,4R)-3-Methyl-4-phenylpiperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amlodipine besilate impurity A is a low-energy impurity that is formed in the crystallization process. It is an amide compound that has a hydrogen bond with crotonic acid and amlodipine, and can be found in acidic environments. The structural formula for this impurity is C8H14NO2S·C4H6O4·CH3OH.</p>

<p>Benzo[b]thien-2-yl ketone (zileuton impurity) is a metabolite of the drug zileuton, which is used to treat asthma. Benzo[b]thien-2-yl ketone is formed by the oxidation of benzo[b]thiophene in the presence of cytochrome P450 enzyme system. It has been found to have anti-inflammatory properties and may be useful for treating asthma. This product is available as an analytical standard for HPLC, or as a custom synthesis for research and development.</p>

<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>

<p>Please enquire for more information about 3-(Diethylamino)-8-methyl-2(1H)-quinolinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dihydro artemisinin tetrahydrofuran acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Prothoate is a medicinal analog that acts as an inhibitor of kinases. It has been shown to have anticancer properties and can induce apoptosis in cancer cells. Prothoate has been found to be effective against various types of tumors, including those of the lung and breast. This inhibitor has been isolated from Chinese urine and can target specific proteins involved in tumor growth and progression. Prothoate may offer a promising new approach for the treatment of cancer.</p>

<p>Pf9 tetrasodium is a high purity, HPLC standard. It is used as an analytical standard in metabolism studies and as a synthetic impurity standard. Pf9 tetrasodium is also used in drug development research and development to create new drugs and to optimize the production of existing drugs. This product is sold in quantities of 100 grams or more. Pf9 tetrasodium has CAS number 851265-78-6.</p>

<p>Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.</p>

<p>Stafib-2 is an analog inhibitor that has shown potent anticancer activity in human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in regulating cell growth and division. Stafib-2 has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells and human cancer cells. This drug also inhibits the activity of elastin kinase, a protein that is involved in tumor growth and metastasis. Stafib-2 has potential as a targeted therapy for cancer treatment due to its ability to selectively inhibit specific kinases involved in cancer progression. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.</p>

<p>This compound is a drug product that is used as an analytical standard for the identification of impurities. This compound is also a Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic and Drug development research chemical. The CAS number for this compound is 170570-01-1 and it has HPLC standards with high purity. This compound is also a Synthetic and Pharmacopoeia Research Chemical with a niche market.</p>

<p>1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is a metabolite of carvedilol. It is not active as a drug, but may have pharmacological effects. 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is used as an impurity standard for HPLC analysis of carvedilol in the pharmaceutical industry.</p>

<p>Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.</p>