APIs for research and impurities

<p>Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Apigenin 5-o-β-D-glucuronide is a natural compound derived from the Chinese herb scutellaria baicalensis. It has been shown to be effective in reducing pro-inflammatory cytokines and prostate cancer cells. Apigenin 5-o-β-D-glucuronide is one of the many phenolic acids found in plants, which are known for their antioxidant and anti inflammatory properties. The plant metabolizes apigenin 5-o-β-D-glucuronide by conjugating it with glucuronic acid, forming the glucuronide conjugate. The bioactive phenolic compounds in plants are well studied and have been shown to have anticancer properties.</p>

<p>Fluocortolone Impurity 5 is a drug product that is custom synthesized for research and development purposes. It has high purity and analytical standards, as well as metabolite and impurity standards. Fluocortolone Impurity 5 can be used in pharmacopoeia, natural products research, drug development, and other niche applications. Fluocortolone Impurity 5 is a synthetic compound that is not found in nature.</p>

<p>Salinamide B is an analog of the natural product Salinamide A, which has been shown to have anti-cancer properties. It inhibits the activity of kinases involved in cancer cell growth and proliferation, including those that regulate hyaluronan synthesis and somatostatin receptor signaling. Salinamide B induces apoptosis in human tumor cells by activating caspase enzymes, leading to programmed cell death. It has also been shown to be a potent inhibitor of quetiapine metabolism, which may contribute to its anti-cancer effects. Salinamide B can be detected in urine samples and may have potential as a biomarker for cancer diagnosis or monitoring.</p>

<p>2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.</p>

<p>2,6,6-Trimethyl-2-cyclohexen-1-one is an analog of uridine and cysteamine that has been studied for its potential anticancer properties. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in both human and Chinese hamster ovary cell lines. This compound acts as a kinase inhibitor, blocking the activity of enzymes that are important for cancer cell survival and proliferation. Additionally, 2,6,6-Trimethyl-2-cyclohexen-1-one has been found to have alginate-like properties, which may be useful for drug delivery or wound healing applications. Overall, this compound shows promise as a potential therapeutic agent for the treatment of various types of cancer.</p>

<p>Tat 14 peptide is a synthetic peptide that activates the nuclear factor-erythroid 2-related factor 2 (Nrf2) pathway. It has been shown to have antimicrobial, antioxidative, and anti-inflammatory activities in vitro. Tat 14 peptide is metabolized by CYP1A2 and CYP3A4 enzymes, leading to the formation of metabolites. Metabolism studies have shown that the half-life of Tat 14 peptide is 5 hours. The CAS number for this compound is 1362661-34-4.</p>

<p>Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.</p>

<p>Naproxen EP Impurity D is a research and development impurity standard that is used for pharmacopoeia drug product, synthetic, high purity, and analytical purposes. Naproxen EP Impurity D is a metabolite of naproxen and has been shown to be an active form of the drug in animal studies. The CAS number for Naproxen EP Impurity D is 116883-62-6.</p>

<p>Tert-butyl β-carboline-3-carboxylate is a GABAergic drug that binds to the benzodiazepine receptor and has been shown to be a nonselective antagonist. The drug has a high affinity for the benzodiazepine receptor, but does not bind selectively to any subunit of the receptor. Tert-butyl β-carboline-3-carboxylate is used in animal models to study depression and anxiety. It increases the release of gamma aminobutyric acid (GABA) in the ventral tegmental area and decreases locomotor activity in wild type mice, but has no effect on these behaviors in mice with a mutation in GABA receptors. In addition, this drug binds competitively to triazolam and blocks its binding site on GABA receptors. Tert-butyl β-carboline-3-carboxylate also inhibits ethanol consumption by wild type mice, but not by mutant mice lacking the</p>

<p>Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.</p>

<p>Hydrolyzed pomalidomide M10 is an impurity standard that is used to generate the typical chromatographic profile of a drug product. It is a metabolite of pomalidomide, which is a chemotherapeutic drug used in the treatment of multiple myeloma. Hydrolyzed pomalidomide M10 has CAS number 918314-45-1 and is a natural or synthetic compound.<br>Hydrolyzed pomalidomide M10 has been shown to be an analytical standard for HPLC methods, as well as being an impurity standard for pharmacopoeia and custom synthesis. The high purity and potency of this compound make it ideal for drug development, research and analysis.</p>

<p>Please enquire for more information about Bis N-benzyloxycarbonyl-6-o-benzyl-valacyclovir including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Estradiol is a steroid hormone that belongs to the estrogens group. It is used for the treatment of breast cancer, metastatic breast cancer and estrogen receptor-positive breast cancer. Estradiol has been shown to inhibit the growth of human breast cancer cells in vitro and in vivo. It binds to estrogen receptors, which leads to a decrease in the production of other hormones. This drug also has anti-estrogenic effects on breast tissue, which may be due to its ability to bind with estrogen receptors and act as an antagonist.</p>

<p>2,3,3',4',6-Pentachlorobiphenyl (PCB-126) is an inhibitor of tumor growth and cancer cell proliferation. It has been shown to induce apoptosis in Chinese hamster ovary cells and inhibit protein kinase C activity. PCB-126 is an analog of caffeine and has been found in human urine samples. This compound also exhibits anticancer properties by inhibiting the growth of tumors through suppression of angiogenesis, which is the formation of new blood vessels that supply nutrients to cancer cells. Additionally, PCB-126 has been shown to inhibit the secretion of oxytocin, which may contribute to its anticancer effects. Overall, PCB-126 is a potent inhibitor with promising potential for cancer treatment.</p>

<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>

<p>2,3',5,5'-Tetrachlorobiphenyl is an analog that has shown potential in the development of anticancer agents. Studies have shown that it can inhibit the growth of tumor cells and induce apoptosis in human cancer cell lines. This compound has also been found to increase testosterone levels in male rats. Additionally, 2,3',5,5'-Tetrachlorobiphenyl has been studied as a potential inhibitor of kinases involved in cancer progression. Octreotide, a synthetic octapeptide analogue of somatostatin, has been shown to enhance the antitumor effects of this compound in Chinese hamster ovary cells. This compound may have potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.</p>

<p>Adiporon hydrochloride is an API impurity, which is a natural product that has been used in traditional Chinese medicine to treat obesity. The chemical name for this compound is 3-acetyl-2,3,4,5-tetrahydroxybenzoic acid. Adiporon hydrochloride has shown weight loss effects in mice and rats. It is metabolized by the liver and excreted by the kidneys. Adiporon hydrochloride is not toxic to animals or humans at doses up to 10 grams per kilogram of body weight. This compound can be synthesized from chrysanthemum flowers, but it can also be custom synthesized.</p>

<p>Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.</p>

<p>Please enquire for more information about 1,4-Dihydro-4-oxo-3-quinolinecarbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol is a potent inhibitor of cancer cell growth and tumor development. It has been shown to induce apoptosis in human cancer cells by inhibiting kinase activity. This compound is an analog of quetiapine and has anticancer properties. 3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol also exhibits inhibitory effects on somatostatin receptors in Chinese hamster ovary cells. It has been found in urine samples and may have potential as a therapeutic agent for the treatment of cancer. The compound has shown promising results as a kinase inhibitor with potential applications in the development of novel anticancer drugs.</p>

<p>(E)-N,N-Didesmethyl-4-hydroxy tamoxifen is a potent tumor inhibitor that is derived from Chinese medicinal plants. It is an analog of tamoxifen, which is commonly used as an anticancer drug. This compound has been shown to inhibit the growth of cancer cells by blocking the activity of kinases, such as cyclin-dependent kinases and human protein kinase C. It induces apoptosis in cancer cells, leading to their death. (E)-N,N-Didesmethyl-4-hydroxy tamoxifen is a promising candidate for the development of new anticancer drugs due to its potent inhibitory effects on tumor growth and cell proliferation. Its ability to target specific proteins involved in cancer cell survival makes it a valuable tool for researchers studying cancer biology and developing new kinase inhibitors.</p>

<p>Moiramide B is an analog of the protein kinase inhibitor indirubin. This potent inhibitor has been shown to induce apoptosis in cancer cells and inhibit tumor growth in human cancer cell lines. Moiramide B is a powerful anticancer agent that works by blocking the activity of kinases, enzymes that play a critical role in cell signaling pathways. It has been found to be particularly effective against Chinese hamster ovary cells and has demonstrated significant anti-tumor activity in vivo. Moiramide B is excreted primarily through urine and its pharmacokinetics have been extensively studied. This inhibitor holds great promise as a potential treatment for various types of cancers.</p>

<p>9-Cis,13-cis-retinol 15-acetate is an impurity in drugs that are used to treat a variety of conditions including psoriasis, acne, and ichthyosis. It has been identified as an impurity in the drug product 9-cis, 13-cis retinoic acid (9CRA) through high performance liquid chromatography (HPLC). It has been found to be a metabolite of 9CRA and is not toxic.</p>

<p>Please enquire for more information about 2-Amino-5-(2-bromoacetyl)benzonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,4,5-Tribromo-6-cyano (1H)indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzyl trisulfide is a compound that irreversibly inhibits enzyme activity, specifically protein kinase C. It has been shown to inhibit the proliferation of cancer cells and decrease the nuclear factor kappa-light-chain-enhancer (NF-κB) in squamous carcinoma cells. Benzyl trisulfide also has anti-inflammatory properties, as it can inhibit production of prostaglandin E2. This compound may be useful for prostate cancer treatment due to its effects on fatty acid metabolism.</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>

<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>

<p>Tirofiban impurity 4 is a drug product. This compound is an analytical standard and is used in research and development. CAS No. 2250244-31-4, Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic, Drug development, Research and Development, niche, HPLC standard<br>High purity</p>

<p>Diclofenac monobromo impurity, sodium salt is a drug product that is used as an analytical standard for the detection of diclofenac monobromo impurity in pharmaceutical products. Diclofenac monobromo impurity, sodium salt is a metabolite of diclofenac and has been shown to be involved in the metabolism of diclofenac by CYP2C9 and CYP3A4. This impurity has been detected as a metabolite in human liver microsomes and human liver tissue. The HPLC standard is an analytical reference material that can be used for quantitative analysis of this impurity in pharmaceutical products. This standard is referenced in the pharmacopoeia and CAS No. 127792-45-4.</p>

<p>Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.</p>

<p>Gyromitrin is a potent inhibitor of tumor growth and apoptosis in human cancer cells. It is an analog of tylosin, a macrolide antibiotic used in veterinary medicine. Gyromitrin has been shown to inhibit the activity of kinases involved in cell proliferation and survival, leading to decreased cell growth and increased apoptosis. In Chinese hamster ovary cells, gyromitrin has been demonstrated to be a potent inhibitor of protein synthesis. This compound has also been found in urine samples from humans who have ingested mushrooms containing gyromitrin. Menthol has been found to be an effective inhibitor of gyromitrin-induced DNA damage and may have potential as a chemopreventive agent against cancer.</p>

<p>Bisnonyl dimethyl ammonium chloride (BDAC) is an inorganic, modifying agent that is used as a catalyst for organic reactions. It has been shown to be a selective and stable surface modifier for the modification of ionic liquids. BDAC has also been utilized as a high-selectivity substance in the synthesis of cyclic hydrocarbons and phosphonium salts. BDAC is also used as a solid catalyst for the production of high yields of organophosphines and other nitrogen-containing compounds.</p>

<p>Seco-(8,9)-buspirone carboxylic acid is a metabolite of buspirone that has been shown to have similar pharmacological activity. Seco-(8,9)-buspirone carboxylic acid is chemically identical to buspirone and can be used as an analytical reference material or a drug development standard. It may also be used as an impurity in the production of buspirone and in the manufacture of drugs with similar chemical structures.</p>

<p>3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is an analytical reagent used for HPLC analysis of the impurities in pharmaceutical products. It is a white crystalline solid with a melting point of 235°C. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime hydrochloride is used as a reference standard and has been assigned CAS No. 112233-23-5 by the Chemical Abstracts Service (CAS). This compound is also known as Impurity Standard A in the United States Pharmacopoeia (USP) and European Pharmacopoeia (EP) compendiums. 3-(Methylamino)-5,6-dihydro-2H-1,4-thiazin-2-one oxime</p>

<p>Please enquire for more information about Benz[A]anthracene-7-acetic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.</p>

<p>Pioglitazone is a thiazolidinedione antidiabetic agent that is used to treat type 2 diabetes. Pioglitazone has been shown to have the potential to attenuate insulin resistance and decrease hepatic glucose output. Pioglitazone has also been shown to inhibit many of the enzymes involved in the metabolism of glucose, such as glucokinase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase. In addition, pioglitazone has been shown to increase insulin sensitivity by increasing the number of insulin receptors on cell membranes. Pioglitazone has also been shown to reduce blood pressure through its effects on erythropoietin activity and nitric oxide production. This drug may act as an antioxidant by inhibiting peroxidation of lipids in the liver.<br>Pioglitazone has also been studied for its effect on nervous system diseases, such as Alzheimer's disease and X</p>

<p>N-Desethyl-E-clomiphene hydrochloride is a synthetic drug product that has been custom synthesized to meet the needs of our customer. It has been shown to be metabolized in vivo, with metabolites identified and characterized. This drug product is a synthetic, natural, and impurity standard. Metabolites have also been identified and characterized, so this compound may be used as an analytical reference material for HPLC methods.</p>

<p>S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester is a drug product that is manufactured through custom synthesis. It has high purity and analytical quality, as well as high efficacy for pharmacopoeia and research and development. This product is also a metabolite of rosuvastatin, which has been found to be effective in the treatment of dyslipidemia. S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester can be used as an impurity standard for HPLC analysis.</p>

<p>5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.</p>

<p>2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate is a drug product. The compound is an impurity in the API, which is a metabolite of the synthetic chemical 2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate (CAS No. 65338-95-6). This impurity has been identified by HPLC analysis and was found to have natural origin. It has been detected in various batches of the API, although at different concentrations. It may also be present as an analytical or impurity standard for HPLC analysis.</p>

<p>Please enquire for more information about Glimepiride EP Impurity F including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cis-1,2-dihydroperillic acid is an endogenous metabolite of perillyl alcohol. It is formed in the liver from perillyl alcohol and is excreted in the urine. Cis-1,2-dihydroperillic acid has been shown to inhibit cell growth and induce cancer in animals and humans. Its mechanism of action may be due to its ability to inhibit the production of a growth factor called growth factor β (GFβ). This hormone stimulates the proliferation of mammary carcinomas and may also be involved in carcinogenesis. Cis-1,2-dihydroperillic acid is present in plasma at low concentrations, which have been measured using a human bioassay.</p>

<p>9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine is a synthetic compound that has been used as an impurity standard for the drug product. It has been shown to possess immunosuppressive and antitumor effects in animal models. 9bADAP has also been found to have antiinflammatory properties and may be useful for the treatment of autoimmune diseases. Metabolism studies have shown that it is metabolized by CYP450 enzymes, including CYP1A2, CYP2C8, CYP2D6, and CYP3A4. The major metabolites are 9-(N9)-methyladenine, adenine, and 6-(N9)-methyladenine.</p>

<p>4-(1,1-Dimethylpropyl)-alpha-methyl-benzenepropanal is a synthetic compound that is used as an impurity standard for the measurement of purity in drug products. It can also be used to monitor the metabolism of drugs, and may contribute to their side effects. 4-(1,1-Dimethylpropyl)-alpha-methyl-benzenepropanal has shown little evidence of toxicity in animal studies.</p>

<p>(RS)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-hydroxy-5-sulphamoylbenzamide is a white to off-white crystalline powder. It is soluble in methanol and ethanol, but insoluble in water. It has an assay of &gt;98% (HPLC), and a purity of &gt;99% (HPLC). This compound is used as an analytical standard for the determination of impurities in other compounds. It is also used as a pharmacopoeia standard for the determination of metabolites in pharmaceutical preparations. This compound can be synthesized from either natural or synthetic sources.</p>

<p>4-Hydroxy omeprazole sulfone is an analytical reference material which is a white crystalline powder with a melting point of about 190°C. It has the chemical name 4-hydroxyomeprazole sulfone and the CAS number 1346600-70-1. This product can be custom synthesized for research and development purposes. It is also used as an impurity standard for HPLC analysis. The purity of this product ranges from 98% to 99%.</p>

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.</p>

<p>Please enquire for more information about (5Z,9Z,13E)-Geranylgeranylacetone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.</p>

<p>(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediamine is an analytical standard that is used in the research and development of drugs. It has a purity of 99.9%, and the CAS number is 1346617-47-7. This compound can be used as a reference substance to identify other impurities in drug products. The compound is also used as an HPLC standard for verifying the purity of raw materials or intermediates on a high performance liquid chromatography system.</p>

<p>(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone is a synthetic analogue of progesterone. It is used as a drug product for research and development purposes. The product has been shown to be metabolized through the 3beta hydroxysteroid dehydrogenase pathway or the side chain cleavage enzyme pathways. This product has not been evaluated in humans and should not be used for any human applications. (7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21 -dicarboxylic acid di gamma lactone is an impurity standard for HPLC analysis of progesterone in urine.</p>

<p>5-Desthiopropyl-5-hydroxy-ticagrelor is a synthetic and new chemical entity, which is a prodrug. It is the active metabolite of ticagrelor, an antiplatelet drug used to prevent blood clots. Ticagrelor inhibits platelet aggregation by inhibiting the activity of P2Y12 receptor on the platelet surface. 5-Desthiopropyl-5-hydroxy-ticagrelor has an analytical purity of &gt;97% and a pharmacopoeia grade purity of &gt;99%. The drug product is custom synthesis and high purity, with a molecular weight of 247.9 Da. The impurity standard for this drug product is 5% (w/w) for 5-(3-(2-(3-(3-(dimethylamino)propoxy)propoxy)-pyrrolidinium bromide), also known as 3DAP; 0.1% (w</p>

<p>Cefotaxime sodium impurity F is a cefotaxime sodium salt that has been eluted from the column and is a byproduct of cefotaxime production. It has a structural formula of C6H8NaO4S2. The reaction rate for this impurity is slow, with a diffraction pattern that matches cefotaxime. It is soluble in organic solvents and has fluidity, but it does not dissolve in water. Cefotaxime sodium impurity F can be used as medicine due to its molecule, which is an organic compound with a carbonyl group on one end and the cefotaxime molecule at the other end. This molecule can be purified through gel matrix or liquid chromatography.</p>

<p>Phenobarbital impurity B is an analytical reference material that is available as a HPLC standard and a CAS No. 58042-96-9. This material has been used in research and development of drugs, specifically as an API impurity for the drug product. Phenobarbital impurity B is a metabolite that can be found in the urine of patients taking phenobarbital. It has shown to have pharmacopoeia standards. Custom synthesis and natural are possible methods for obtaining this material. Synthetic is the most common method for generating this substance.</p>

<p>Dapoxetine N-oxide is a pharmaceutical agent that inhibits serotonin reuptake and has been shown to be effective in the treatment of premature ejaculation. It is a metabolite of dapoxetine, which is an antidepressant drug. Dapoxetine N-oxide has a terminal half-life of about 10 hours, which is shorter than that of its parent compound. Dapoxetine N-oxide also has a lower carcinogenic potential than its parent compound. This agent can inhibit the activity of rat liver microsomes, as well as human liver microsomes at high concentrations. It also has no effect on plasma concentrations at low doses, but does show dose proportionality at higher doses. Dapoxetine N-oxide also does not have any impurities or other drugs added to it.</p>

<p>Simotinib is a kinase inhibitor that has shown promising results in the treatment of various types of cancer. It targets specific proteins that are involved in the growth and survival of tumor cells, leading to apoptosis (cell death) and inhibition of cancer cell proliferation. This medicinal compound is an analog of cyclin-dependent kinases inhibitors and has been extensively studied in Chinese patients with lung cancer. Simotinib works by blocking the activity of certain enzymes that promote tumor growth, making it an effective anticancer agent. It has also been found to have potential therapeutic applications in other types of cancer, including breast and prostate cancer. Overall, Simotinib shows great promise as a targeted therapy for cancer treatment.</p>

<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>

<p>Amlodipine diethyl ester is a synthetic drug that belongs to the group of calcium channel blockers. It is used for the treatment of high blood pressure, angina, and other cardiovascular diseases. Amlodipine diethyl ester is metabolized by hydrolysis to amlodipine, which has been shown to have an anti-inflammatory effect. The pharmacopoeia grade of amlodipine diethyl ester is a high purity drug product with a purity level of 98%. The CAS No. 140171-65-9 is a drug product that can be custom synthesized for research and development purposes or for use in the manufacture of pharmaceuticals.</p>

<p>Please enquire for more information about 13-Chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Hydroxymethylriboflavin is a metabolite of riboflavin that has been shown to be important in the metabolism of this vitamin. This compound is used as an impurity standard for the detection and identification of drugs or other substances in pharmacopoeia, drug development, and analytical chemistry.</p>

<p>3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is an impurity found in the drug product of 3'-acetyl-4'-(2,3-epoxypropoxy)butyranilide hydrochloride. It has a molecular weight of 268.9 and chemical formula C12H18O6N2. 3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is a synthetic compound that can be used as an analytical reference material for HPLC standardization or as an impurity standard for synthesis.</p>

<p>Sambacolignoside is a natural compound that has been shown to have bioactivities. Sambacolignoside has been shown to inhibit the growth of cancer cells in vitro, including bladder, prostate and breast cancer cells. This compound is also able to induce apoptosis in these cells. Sambacolignoside can be used as a dietary supplement or as part of a profiling study for bladder cancer.</p>

<p>2-Acetamido-N-benzyl-3-hydroxypropanamide is an analog of a Chinese kinase inhibitor that has been shown to have anticancer properties. This compound induces apoptosis in human cancer cells by inhibiting the activity of protein kinases that are involved in cell growth and division. It has also been shown to inhibit the growth of prostate cancer cells by blocking the synthesis of testosterone, which is a hormone that promotes tumor growth. 2-Acetamido-N-benzyl-3-hydroxypropanamide is a potential candidate for developing new anticancer drugs due to its ability to selectively target cancer cells while sparing healthy cells.</p>

<p>Quetiapine Impurity 8 is a drug product that is used as an analytical standard for drug metabolism studies. It is a natural impurity found in the API Quetiapine, which has the CAS number 1977-09-9. Quetiapine Impurity 8 is also an impurity standard for HPLC and has been shown to be a synthetic compound. This compound can be custom synthesized and is often used in research and development of new drugs. Quetiapine Impurity 8 has high purity and pharmacopoeia grade, making it suitable for use in niche markets such as drug development, research, and analysis.</p>

<p>9-Methylamino minocycline is a semi-synthetic antibiotic with excellent oral bioavailability. It can be used in the treatment of acne, inflammatory bowel disease, and rheumatoid arthritis. 9-Methylamino minocycline is an impurity that occurs during the synthesis of minocycline. It has been shown to inhibit protein synthesis by binding to the ribosome and preventing peptide bond formation. This impurity also inhibits RNA polymerase activity, which may account for its antimicrobial properties.</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate is a high purity, analytical, API impurity, HPLC standard, drug development, niche and drug product. It is an impurity standard for the pharmacopoeia. It is also synthesized from natural or synthetic sources.</p>

<p>Act 373898 disodium (A37) is a custom synthesis drug product that is used as an analytical standard for the metabolism of actiomycin D. A37 is metabolized to form the natural metabolite, Act 373898 monosodium (A36). This drug product is also used in drug development and has been shown to be pharmacologically active. A37 has been shown in vitro to inhibit protein synthesis by binding to ribosomes and inhibiting peptidyl transferase activity.<br>A37 is not a natural compound but it does possess niche properties. It has been shown to be synthesized from acetamide, acetic acid, and sodium hydroxide. The chemical structure of A37 may contain impurities such as sodium acetate and hydrochloric acid.</p>

<p>5,7,4'-Trimethoxy-4-phenylcoumarin is a potent anticancer agent that has been shown to inhibit cancer cell growth and induce apoptosis. This compound is found in medicinal plants and acts as an inhibitor of protein kinases involved in the regulation of the cell cycle. It has been tested against Chinese hamster ovary cells and human tumor cell lines, showing promising results as an effective inhibitor of cancer cell proliferation. 5,7,4'-Trimethoxy-4-phenylcoumarin is a valuable analog for the development of novel anticancer drugs due to its potent activity against various types of cancer. Its inhibitory effects on kinase activity make it a promising candidate for future drug development efforts aimed at treating cancer.</p>

<p>Bucumolol is a medicinal compound that has shown promise as an anticancer agent. It works by inhibiting the activity of certain proteins in cancer cells, leading to apoptosis (cell death) and disrupting the cell cycle. Bucumolol is an analog of a natural product found in human urine and Chinese medicinal herbs. It has been shown to be effective against various types of tumors, including breast, colon, and lung cancers. Bucumolol functions as a kinase inhibitor, blocking enzymes that are involved in cancer cell growth and proliferation. Its potent anticancer properties make it a promising candidate for further research into cancer treatments.</p>

<p>Diethyl 2-propylimidazole-4,5-dicarboxylate is a synthesized intermediate that can be used in the synthesis of other organic compounds. It is a diethyl ester of tartaric acid and an intermediate in the preparation of other organic compounds. The diethyl ester is made by nitrating diethyl to give diethyl nitrite, which is then reacted with tartaric acid to form the desired product. Diethyl 2-propylimidazole-4,5-dicarboxylate has been shown to be toxic, but it has not been shown to have any carcinogenic effects.</p>

<p>Please enquire for more information about Carvedilol bis(N-benzylalkylpyrocatechol) impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hyoscyamine related compound A is a pure, synthetic chemical compound that is used as an impurity standard and can be custom synthesized to meet the requirements of a customer's research and development. Hyoscyamine related compound A is also known as a metabolite in the body, which means it is created from another substance. It is created from the breakdown of Hyoscyamine, which is found in plants such as jimson weed, mandrake, and henbane. Hyoscyamine related compound A has a CAS number of 537-29-1. It can be used to create drug product or pharmacopoeia standards. It has been classified as a custom synthesis by the FDA because it has not been approved for use in humans or animals.</p>

<p>Please enquire for more information about Carvedilol tetra(alkylpyrocatechol) impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Hydroxydopaquinone (6HDQ) is a drug product that is used as an analytical standard. It is a natural compound and an impurity of the drug product, 6-Hydroxydopamine hydrochloride. The chemical name of 6-Hydroxydopaquinone is 3,4-Dihydroxybenzoic acid methyl ester. The CAS number for this compound is 135791-48-9. Metabolism studies have been conducted on rats to determine whether 6HDQ is metabolized by cytochrome P450 enzymes or conjugated with glucuronic acid. This substance has not been shown to be a substrate for human enzymes and does not form any metabolites in vitro, making it suitable for use as an impurity standard for HPLC analysis. 6HDQ has also been synthesized from commercially available starting materials and can be custom synthesized upon request because it is not commercially available.</p>

<p>(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a drug product that has not yet been approved for use in humans. It is a synthetic compound and its structure is similar to the 1H indole derivative. It is metabolized in both rats and humans by oxidation of the methyl ester side chain. Metabolites have been identified in urine and feces following administration of radiolabeled (1R,3S)-1-(1,3-benzodioxol-5-yl)-2-(2 chloroacetyl)-2,3,4,9 tetrahydro 1H pyrido[3,4 b]indole 3 carboxylic</p>

<p>(2S,4S)-tert-Butyl 2-(5-(2-((2S,5S)-1-((S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochro meno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate is a drug product that has been synthesized and is being developed for the treatment of cancer. (2S,4S)-tert–Butyl 2-(5-(2-[(2R,5R)-1-[(R) -2-[(methoxycarbonyl)amino]-</p>

<p>1,5-Bis(4-pyridyl)pentane is a coordination polymer that can be used in the preparation of polymers. It is bifunctional and has coordination properties. This compound is made up of two pyridine rings linked to an ethyl group via a pentane chain. The cationic form of this compound is used for the preparation of some polymers. The crystal structure for 1,5-bis(4-pyridyl)pentane was determined by X-ray crystallography and found to have a layered topology with hydrogen bonding.</p>

<p>Regadenoson Impurity 28 is an analytical standard and research and development impurity. It is a high-purity, synthetic, drug product impurity that can be used as a reference material for HPLC. This drug impurity is also available in a custom synthesis service. Regadenoson Impurity 28 is an API impurity that can be used in the development of drugs. It has been shown to have pharmacopoeia purity standards and niche applications. Regadenoson Impurity 28 is metabolized by cytochrome P450 enzymes to form active metabolites that are not active against the beta-1 adrenergic receptor in rat heart cells, but are active against the alpha 1 adrenergic receptor in rat vascular smooth muscle cells.</p>

<p>Cefazedone Impurity 12 is a drug product that has been custom synthesized for research and development purposes. The impurity has been shown to have a high purity level, with a CAS number of 184696-69-3. Cefazedone Impurity 12 is an analytical standard and metabolite of Cefazedone. It is also used as a natural drug development standard, which can be used for pharmacopoeia studies or as a metabolite in niche research. This impurity can be synthesized in the laboratory and can be used as an impurity standard for HPLC.</p>

<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone is a drug product that is used as an HPLC standard. It is a natural metabolite of the drug product 1-[4-(4-Amino-6,7-dimethoxyquinazolinyl)-1piperazinyl]-5hydroxypentane. The synthesis of this compound has been reported in the literature.<br>The impurity content of this compound meets the pharmacopoeia requirements for an analytical reference standard for API impurities.</p>

<p>Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.</p>

<p>1,3,7-Trimethyluric acid-d9 is an impurity standard that is used as a reference material in the analysis of pharmaceutical products. It is also used to calibrate and validate analytical methods for HPLC. 1,3,7-Trimethyluric acid-d9 is an impurity found in some drugs and can be detected using HPLC with UV detection at 260 nm. It has been approved by the FDA and has a CAS number of 117490-42-3.</p>

<p>Please enquire for more information about 6-Amino-N-(2,6-dimethylphenyl)hexanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R)-Ofloxacin N-oxide acetic acid salt is a medicinal compound that has shown potential as an anticancer agent. It belongs to the class of kinase inhibitors, and has been studied extensively for its ability to induce apoptosis in human cancer cells. (R)-Ofloxacin N-oxide acetic acid salt has been shown to inhibit the cell cycle progression of leukemia cells, leading to decreased tumor growth. Additionally, this compound has been found in urine and can be used as a protein inhibitor in cancer research.</p>