Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Fórmula:C18H29NO3Pureza:99.61% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43WP1066
CAS:<p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Cor e Forma:SolidPeso molecular:356.22(S)-(+)-Rolipram
CAS:<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Fórmula:C16H21NO3Pureza:99.14%Cor e Forma:SolidPeso molecular:275.34Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Fórmula:C19H16ClN2NaO3Cor e Forma:SolidPeso molecular:378.79Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Fórmula:C30H28FN7O3Pureza:99.53% - 99.79%Cor e Forma:SolidPeso molecular:553.59M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Fórmula:C13H16O4Pureza:97.8%Cor e Forma:SolidPeso molecular:236.26Notoginsenoside R1
CAS:<p>Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.</p>Fórmula:C47H80O18Pureza:99.57% - >99.99%Cor e Forma:SolidPeso molecular:933.13Geranylgeraniol
CAS:<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Fórmula:C20H34OPureza:99.17% - ≥98%Cor e Forma:SolidPeso molecular:290.48Avelumab
CAS:<p>Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.</p>Pureza:95% - 97.17% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:143.8 kDaSW106065
CAS:<p>SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.</p>Fórmula:C10H8N2OSPureza:99.97%Cor e Forma:SolidPeso molecular:204.25(ZE)-SU9516
CAS:<p>(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.</p>Fórmula:C13H11N3O2Pureza:99.59%Cor e Forma:SolidPeso molecular:241.25Spautin-1
CAS:<p>Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.</p>Fórmula:C15H11F2N3Pureza:97.69% - 98.99%Cor e Forma:SolidPeso molecular:271.26Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Fórmula:C24H28N2O9Pureza:97.46%Cor e Forma:SolidPeso molecular:488.49JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Cor e Forma:SolidPeso molecular:394.36ML141
CAS:<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Cor e Forma:SolidPeso molecular:407.49Diclofenac Potassium
CAS:<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Fórmula:C14H10Cl2KNO2Pureza:99.51%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:334.24SSE15206
CAS:<p>SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.</p>Fórmula:C19H21N3O3SPureza:98.81%Cor e Forma:SolidPeso molecular:371.45PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Cor e Forma:SolidPeso molecular:347.39MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Fórmula:C20H20N2OPureza:98.17% - 99.754%Cor e Forma:SolidPeso molecular:304.39SKLB-163
CAS:<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Fórmula:C18H16ClN3O2S2Pureza:99.23%Cor e Forma:SolidPeso molecular:405.92Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Fórmula:C22H34N4O13Pureza:98.54%Cor e Forma:SolidPeso molecular:562.52Fasentin
CAS:<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Fórmula:C11H9ClF3NO2Pureza:99.95%Cor e Forma:SolidPeso molecular:279.64Mitoxantrone diacetate
CAS:<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Fórmula:C26H36N4O10Cor e Forma:SolidPeso molecular:564.592ONO-8130
CAS:<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Fórmula:C25H28N2O5S2Pureza:97.82%Cor e Forma:SolidPeso molecular:500.63PD173074
CAS:<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Fórmula:C28H41N7O3Pureza:98.15% - 98.21%Cor e Forma:Yellow SolidPeso molecular:523.67Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Fórmula:C27H36N6O3SPureza:97.31% - 99.96%Cor e Forma:SolidPeso molecular:524.68Dimethyl malonate
CAS:<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Fórmula:C5H8O4Pureza:≥95%Cor e Forma:LiquidPeso molecular:132.11Itanapraced
CAS:<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Fórmula:C16H11Cl2FO2Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:325.16Tofacitinib Citrate
CAS:<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Fórmula:C22H28N6O8Pureza:99.19% - 99.75%Cor e Forma:SolidPeso molecular:504.49Estramustine phosphate sodium
CAS:<p>Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.</p>Fórmula:C23H30Cl2NNa2O6PPureza:96.44% - 99.54%Cor e Forma:SolidPeso molecular:564.35Rigosertib sodium
CAS:<p>Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.</p>Fórmula:C21H24NNaO8SPureza:98% - 99.37%Cor e Forma:SolidPeso molecular:473.47Siremadlin
CAS:<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Fórmula:C26H24Cl2N6O4Pureza:99.30% - 99.76%Cor e Forma:SolidPeso molecular:555.41Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Cor e Forma:SolidPeso molecular:360.31Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Cor e Forma:SolidPeso molecular:402.66SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Fórmula:C21H21BrN4O5Pureza:99.13%Cor e Forma:SolidPeso molecular:489.322BAct
CAS:<p>2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response</p>Fórmula:C19H16ClF3N4O3Pureza:97.97% - 99.04%Cor e Forma:SolidPeso molecular:440.8Meloxicam sodium
CAS:<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Fórmula:C14H12N3NaO4S2Cor e Forma:SolidPeso molecular:373.38Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Fórmula:C23H27F3N4O10Pureza:95.74% - 99%Cor e Forma:SolidPeso molecular:576.483'-Hydroxypterostilbene
CAS:<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Fórmula:C16H16O4Pureza:98.25% - 99.19%Cor e Forma:SolidPeso molecular:272.3Benzoylpaeoniflorin
CAS:<p>1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.</p>Fórmula:C30H32O12Pureza:95.86% - 97.28%Cor e Forma:SolidPeso molecular:584.57Cinchonine monohydrochloride hydrate
CAS:<p>Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.</p>Fórmula:C19H25ClN2O2Cor e Forma:SolidPeso molecular:348.87Ulinastatin
CAS:<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Fórmula:C13H16O3Pureza:98%Cor e Forma:SolidPeso molecular:220.10994Droxinostat
CAS:<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Fórmula:C11H14ClNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:243.69(-)-Epipodophyllotoxin
CAS:<p>(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.</p>Fórmula:C22H22O8Pureza:99.97%Cor e Forma:SolidPeso molecular:414.41Lycorine
CAS:<p>Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.</p>Fórmula:C16H17NO4Pureza:98.60% - 99.95%Cor e Forma:SolidPeso molecular:287.31RG7112
CAS:<p>RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.</p>Fórmula:C38H48Cl2N4O4SPureza:99.66% - 99.9%Cor e Forma:SolidPeso molecular:727.788-Bromo-cAMP sodium salt
CAS:<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Fórmula:C10H10BrN5NaO6PPureza:98% - 99.94%Cor e Forma:Off-White PowderPeso molecular:430.08C5 Lenalidomide
CAS:<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Fórmula:C13H13N3O3Pureza:99.4%Cor e Forma:SolidPeso molecular:259.26Kinetin riboside
CAS:<p>Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)</p>Fórmula:C15H17N5O5Pureza:98.17%Cor e Forma:White SolidPeso molecular:347.33Domatinostat tosylate
CAS:<p>4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).</p>Fórmula:C30H29N5O6S2Pureza:97.35% - >99.99%Cor e Forma:Solid PowderPeso molecular:619.71Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Cor e Forma:SolidPeso molecular:507.56D-Pantothenic acid hemicalcium salt
CAS:<p>D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.</p>Fórmula:C9H17NO5CaPureza:98% - 99.89%Cor e Forma:White Crystalline PowderPeso molecular:239.28AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Fórmula:C21H21N3O2SPureza:97.24% - 99.83%Cor e Forma:SolidPeso molecular:379.48Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Cor e Forma:SolidPeso molecular:469.94BAY 61-3606 dihydrochloride
CAS:<p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>Fórmula:C20H18N6O3·2HClPureza:99.46%Cor e Forma:SolidPeso molecular:463.32Flupentixol dihydrochloride
CAS:<p>Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.</p>Fórmula:C23H27Cl2F3N2OSPureza:98.76% - >99.99%Cor e Forma:White Or Off-White SolidPeso molecular:507.43Shield-1
CAS:<p>Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.</p>Fórmula:C42H56N2O10Pureza:99.08%Cor e Forma:SolidPeso molecular:748.9(6R)-FR054
CAS:<p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>Fórmula:C14H19NO8Pureza:99.61%Cor e Forma:SolidPeso molecular:329.3BAY 11-7082
CAS:<p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>Fórmula:C10H9NO2SPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:207.25β-Elemonic Acid
CAS:<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Fórmula:C30H46O3Pureza:99.61% - 99.8%Cor e Forma:SolidPeso molecular:454.68Benzyl isothiocyanate
CAS:<p>BITC, found in cruciferous veggies, exhibits anticancer, antimicrobial, and immunomodulatory effects.</p>Fórmula:C8H7NSPureza:99.25% - 99.83%Cor e Forma:Clear Yellow LiquidPeso molecular:149.21Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Fórmula:C19H20O5Pureza:97.22% - 99.84%Cor e Forma:SolidPeso molecular:328.364-Methylsalicylic acid
CAS:<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Fórmula:C8H8O3Pureza:99.64%Cor e Forma:Solid Solid CrystallinePeso molecular:152.154-Nitroquinoline 1-oxide
CAS:<p>4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of</p>Fórmula:C9H6N2O3Pureza:97.4% - 99.94%Cor e Forma:Yellow Needles Or Plates From Acetone Physical Description Yellowish-Brown Plates Or Needles Or Yellow Solid (Ntp 1992)Peso molecular:190.16Stavudine sodium
CAS:<p>Stavudine sodium, an oral HIV-1/2 inhibitor, also hinders mtDNA replication, NLRP3 inflammasome, and Amyloid-β autophagy, prompting apoptosis.</p>Fórmula:C10H11N2NaO4Cor e Forma:SolidPeso molecular:246.198OTS964
CAS:<p>OTS964 is an oral TOPK inhibitor (IC50: 28nM), also targets CDK11, especially CDK11B (Kd: 40nM).</p>Fórmula:C23H24N2O2SCor e Forma:SolidPeso molecular:392.51Dauricine
CAS:<p>1.</p>Fórmula:C38H44N2O6Pureza:99.24% - 99.75%Cor e Forma:White PowderPeso molecular:624.77Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Cor e Forma:SolidPeso molecular:288.43AZD-8055
CAS:<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Fórmula:C25H31N5O4Pureza:98% - 99.69%Cor e Forma:SolidPeso molecular:465.54Piclidenoson
CAS:<p>Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.</p>Fórmula:C18H19IN6O4Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:510.29Azathioprine Sodium
CAS:<p>Azathioprine Sodium is a pro-drug converted to 6-MP, inhibiting DNA/RNA synthesis, curbing cell proliferation, especially in lymphocytes.</p>Fórmula:C9H6N7NaO2SCor e Forma:SolidPeso molecular:299.24L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Fórmula:C8H19ClN2O3SCor e Forma:SolidPeso molecular:258.77BML-277
CAS:<p>BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor.</p>Fórmula:C20H14ClN3O2Pureza:98.03% - ≥95%Cor e Forma:Tan SolidPeso molecular:363.8Tangeretin
CAS:<p>Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective</p>Fórmula:C20H20O7Pureza:98.83% - 98.97%Cor e Forma:Yellow CrystallinePeso molecular:372.37Torkinib
CAS:<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Fórmula:C16H16N6OPureza:99.11%Cor e Forma:SolidPeso molecular:308.34Avitinib maleate
CAS:<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C30H30FN7O6Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:603.61Dracorhodin perchlorate
CAS:<p>Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer.</p>Fórmula:C17H15ClO7Pureza:98.31% - ≥95%Cor e Forma:SolidPeso molecular:366.75Vandetanib hydrochloride
CAS:<p>Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).</p>Fórmula:C22H25BrClFN4O2Cor e Forma:SolidPeso molecular:511.81Ferrostatin-1
CAS:<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Cor e Forma:SolidPeso molecular:262.35Rosiglitazone potassium
CAS:<p>Rosiglitazone (BRL 49653) is an oral PPARγ agonist (EC50: 60 nM), TRPC5 activator (EC50: 30 μM), and TRPM3 inhibitor, used in obesity and diabetes research.</p>Fórmula:C18H18KN3O3SCor e Forma:SolidPeso molecular:395.52MK-2206
CAS:<p>MK-2206: selective Akt inhibitor, oral, targets Akt1, Akt2, Akt3; effective in breast cancer, PIK3CA mutants, PTEN-deficient cells.</p>Fórmula:C25H22ClN5OCor e Forma:SolidPeso molecular:443.94Milademetan free base
CAS:<p>Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.</p>Fórmula:C37H42Cl2FN5O7SPureza:98%Cor e Forma:SolidPeso molecular:790.73Panobinostat lactate
CAS:<p>Panobinostat lactate: potent, non-selective, oral HDAC inhibitor; treats refractory multiple myeloma.</p>Fórmula:C24H29N3O5Cor e Forma:SolidPeso molecular:439.512Afimetoran
CAS:<p>Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.</p>Fórmula:C26H32N6OPureza:99.81% - 99.94%Cor e Forma:SolidPeso molecular:444.57LYN-1604 hydrochloride
CAS:<p>LYN-1604 HCl activates ULK1 (EC50: 18.94 nM); key for studying TNBC.</p>Fórmula:C33H44Cl3N3O2Cor e Forma:SolidPeso molecular:621.08PF-573228
CAS:<p>PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.</p>Fórmula:C22H20F3N5O3SPureza:96.58% - 99.51%Cor e Forma:SolidPeso molecular:491.49AX-024
CAS:<p>AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.</p>Fórmula:C21H22FNO2Cor e Forma:SolidPeso molecular:339.4Osthole
CAS:<p>Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.</p>Fórmula:C15H16O3Pureza:99.93% - 99.96%Cor e Forma:Fine White PowderPeso molecular:244.29Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Fórmula:C15H20O2Pureza:99.02% - 99.66%Cor e Forma:Crystalline PowderPeso molecular:232.32Bomedemstat
CAS:<p>Bomedemstat (IMG-7289),Irreversible LSD1 inhibitor. Active in MPN models. Antineoplastic effects. Used in AML and myelofibrosis research.</p>Fórmula:C28H34FN7O2Pureza:99.00%Cor e Forma:SolidPeso molecular:519.61Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Fórmula:C21H22O5Pureza:99.03% - 99.9%Cor e Forma:SolidPeso molecular:354.4MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Cor e Forma:SolidPeso molecular:314.38TCS-PIM-1-4a
CAS:<p>SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).</p>Fórmula:C11H6F3NO2SPureza:99.89%Cor e Forma:SolidPeso molecular:273.23Dihydrorotenone
CAS:<p>Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.</p>Fórmula:C23H24O6Pureza:98.98% - 99.58%Cor e Forma:SolidPeso molecular:396.43Methyl protodioscin
CAS:<p>Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.</p>Fórmula:C52H86O22Pureza:99.308% - 99.73%Cor e Forma:SolidPeso molecular:1063.23Sodium taurodeoxycholate hydrate
CAS:<p>Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations of</p>Fórmula:C26H44NO6S·Na·H2OPureza:99.78%Cor e Forma:SolidPeso molecular:539.7Isatin
CAS:<p>Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.</p>Fórmula:C8H5NO2Pureza:98.92%Cor e Forma:Yellow To Reddish Crystalline SolidPeso molecular:147.13BDA-366
CAS:<p>BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its</p>Fórmula:C24H29N3O4Pureza:98.61%Cor e Forma:SoildPeso molecular:423.5Medicarpin
CAS:<p>Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.</p>Fórmula:C16H14O4Pureza:99.32% - 99.86%Cor e Forma:SolidPeso molecular:270.28Apremilast
CAS:<p>Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.</p>Fórmula:C22H24N2O7SPureza:98.13% - 99.95%Cor e Forma:SolidPeso molecular:460.50Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Fórmula:C9H10O5Pureza:98.4% - 99.74%Cor e Forma:SolidPeso molecular:198.17TPCA-1
CAS:<p>TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases</p>Fórmula:C12H10FN3O2SPureza:95.03% - 97.86%Cor e Forma:SolidPeso molecular:279.29Poziotinib
CAS:<p>Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).</p>Fórmula:C23H21Cl2FN4O3Pureza:98.69% - 99.78%Cor e Forma:SolidPeso molecular:491.34BG45
CAS:<p>BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.</p>Fórmula:C11H10N4OPureza:99.77%Cor e Forma:SolidPeso molecular:214.22Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Fórmula:C23H25ClN6O3Pureza:98.07% - 98.78%Cor e Forma:SolidPeso molecular:468.94Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Fórmula:C20H36O2Pureza:99.58% - 99.97%Cor e Forma:White Fine PowderPeso molecular:308.5PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Fórmula:C130H206N42O45SPureza:96.64%Cor e Forma:SolidPeso molecular:3109.35Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Fórmula:C8H16O2Pureza:97.78% - 99%Cor e Forma:Colourless To Pale Yellow Liquid ViscousPeso molecular:144.21PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Cor e Forma:SolidPeso molecular:320.34DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Fórmula:C16H14N2O3Pureza:99.57%Cor e Forma:SolidPeso molecular:282.29Pyrogallol
CAS:<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Fórmula:C6H6O3Pureza:99.88%Cor e Forma:SoildPeso molecular:126.11Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Fórmula:C22H22O7Pureza:99.65% - 99.84%Cor e Forma:SolidPeso molecular:398.41Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Fórmula:C14H19Br2ClN4SPureza:99.86%Cor e Forma:SolidPeso molecular:470.7Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.45iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Cor e Forma:SolidPeso molecular:394.53Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Fórmula:C32H48N4O8·HClPureza:99.94%Cor e Forma:SolidPeso molecular:653.21EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.43-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Cor e Forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:SolidPeso molecular:428.82Solamargine
CAS:<p>Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.</p>Fórmula:C45H73NO15Pureza:99.17% - 99.96%Cor e Forma:SolidPeso molecular:868.06EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Cor e Forma:SolidPeso molecular:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.27Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Cor e Forma:SolidPeso molecular:409.261R,3S-RSL 3
CAS:<p>1R,3S-RSL 3 is a harmala alkaloid.</p>Fórmula:C23H21ClN2O5Pureza:99.51%Cor e Forma:SolidPeso molecular:440.88Amcasertib
CAS:<p>Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.</p>Fórmula:C31H33N5O2SPureza:97.56% - >99.99%Cor e Forma:SolidPeso molecular:539.69TPCK
CAS:<p>TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis</p>Fórmula:C17H18ClNO3SPureza:97.33%Cor e Forma:PowderPeso molecular:351.85L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Fórmula:C13H13ClN4OSPureza:98.6% - 99.13%Cor e Forma:SolidPeso molecular:308.79Tenilsetam
CAS:<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Fórmula:C8H10N2OSPureza:99.52%Cor e Forma:SolidPeso molecular:182.24Benzarone
CAS:<p>Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.</p>Fórmula:C17H14O3Pureza:99.77%Cor e Forma:SolidPeso molecular:266.29Isobutylparaben
CAS:<p>Isobutylparaben is a preservative and preservative insecticide.</p>Fórmula:C11H14O3Pureza:99.36%Cor e Forma:White CreamPeso molecular:194.23Quinocetone
CAS:<p>Quinocetone is an animal growth promoter and potential anti-tumor activity.</p>Fórmula:C18H14N2O3Pureza:98.06%Cor e Forma:SolidPeso molecular:306.32NSC 3852
CAS:<p>NSC 3852 is a potent inhibitor of histone deacetylase.</p>Fórmula:C9H6N2O2Pureza:99.64%Cor e Forma:Slightly Yellow To Yellow-Green PowderPeso molecular:174.16Hexamethylene bisacetamide
CAS:<p>Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.</p>Fórmula:C10H20N2O2Pureza:99.94%Cor e Forma:White FlakesPeso molecular:200.28PDL-1 cpd 10
CAS:<p>PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.</p>Fórmula:C21H23N5O2Pureza:97.08%Cor e Forma:SolidPeso molecular:377.44PD184161
CAS:<p>PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].</p>Fórmula:C17H13BrClF2IN2O2Pureza:99.40%Cor e Forma:SolidPeso molecular:557.56Z-DEVD-FMK
CAS:<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Cor e Forma:SolidPeso molecular:668.66Pitstop 2
CAS:<p>Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain. Pitstop2 has antitumor activity. Cost-effective, quality assurance.</p>Fórmula:C20H13BrN2O3S2Pureza:99.54%Cor e Forma:SolidPeso molecular:473.36ZM 336372
CAS:<p>ZM 336372 is a potent and selective c-Raf inhibitor.</p>Fórmula:C23H23N3O3Pureza:97.24% - 97.51%Cor e Forma:SolidPeso molecular:389.45Buparlisib
CAS:<p>Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).</p>Fórmula:C18H21F3N6O2Pureza:95.32% - 98.45%Cor e Forma:SolidPeso molecular:410.39Amsilarotene
CAS:<p>Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.</p>Fórmula:C20H27NO3Si2Pureza:98.05%Cor e Forma:SolidPeso molecular:385.6Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Fórmula:C19H20N4O·C7H8O3SPureza:99.34% - 99.87%Cor e Forma:SolidPeso molecular:492.59Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Fórmula:C20H21N3O2·HClPureza:97.24% - 99.15%Cor e Forma:SolidPeso molecular:371.86Ganoderenic acid D
CAS:<p>Ganoderenic acid D, extracted from Ganoderma lucidum, triggers apoptosis and halts cancer cell growth.</p>Fórmula:C30H40O7Pureza:99.05%Cor e Forma:SolidPeso molecular:512.63Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Fórmula:C47H55ClF3N5O6S3Pureza:95.82% - >99.99%Cor e Forma:Pale Yellow SolidPeso molecular:974.61Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Fórmula:C15H17ClFNO4SPureza:99.31% - >99.99%Cor e Forma:SolidPeso molecular:361.82YK-4-279
CAS:<p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>Fórmula:C17H13Cl2NO4Pureza:99.80% - ≥95%Cor e Forma:SolidPeso molecular:366.2NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Fórmula:C38H47ClN4O4Pureza:98.77%Cor e Forma:SolidPeso molecular:659.26Amifostine thiol dihydrochloride
CAS:<p>Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.</p>Fórmula:C5H16Cl2N2SPureza:>99.99%Cor e Forma:SolidPeso molecular:207.165GW 5074
CAS:<p>GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.</p>Fórmula:C15H8Br2INO2Pureza:99.32%Cor e Forma:SolidPeso molecular:520.94YH239-EE
CAS:<p>YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.</p>Fórmula:C25H27Cl2N3O4Pureza:99.61%Cor e Forma:SolidPeso molecular:504.41Didymin
CAS:<p>Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.</p>Fórmula:C28H34O14Pureza:99.12% - 99.87%Cor e Forma:Faintly Beige PowderPeso molecular:594.563,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Fórmula:C15H10O4Pureza:99.92%Cor e Forma:SolidPeso molecular:254.24Nystatin
CAS:<p>Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat</p>Fórmula:C47H75NO17Pureza:69.55% - 99.53%Cor e Forma:Yellow SuspensionPeso molecular:926.1CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Cor e Forma:SolidPeso molecular:541.72KEA1-97
CAS:<p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>Fórmula:C15H9Cl2FN4Pureza:97.07%Cor e Forma:SolidPeso molecular:335.16Pralatrexate
CAS:<p>Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate</p>Fórmula:C23H23N7O5Pureza:94.32% - 99.59%Cor e Forma:SolidPeso molecular:477.47Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Fórmula:C20H15ClN4·2HClPureza:99.16%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:419.73ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Cor e Forma:SolidPeso molecular:511.59XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Fórmula:C25H28N6O2Pureza:99.19%Cor e Forma:SolidPeso molecular:444.53tubuloside B
CAS:<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Fórmula:C31H38O16Pureza:97.59% - 99.72%Cor e Forma:SolidPeso molecular:666.62Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Fórmula:C33H52O8Pureza:97.17% - 99.44%Cor e Forma:SolidPeso molecular:576.76Tauroursodeoxycholate dihydrate
CAS:<p>Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.</p>Fórmula:C26H49NO8SPureza:99.82%Cor e Forma:SolidPeso molecular:535.73Alisertib
CAS:<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Fórmula:C27H20ClFN4O4Pureza:98.31% - >99.99%Cor e Forma:SolidPeso molecular:518.92Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Fórmula:C22H28N4O6Pureza:96.29% - 98.74%Cor e Forma:Blue PowderPeso molecular:444.48G-749
CAS:<p>G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.</p>Fórmula:C25H25BrN6O2Pureza:98.32% - 99.60%Cor e Forma:SolidPeso molecular:521.41Obacunone
CAS:<p>Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.</p>Fórmula:C26H30O7Pureza:98% - ≥95%Cor e Forma:White PowderPeso molecular:454.51Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43Scopoletin
CAS:<p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>Fórmula:C10H8O4Pureza:97.06% - 99.88%Cor e Forma:Yellow To Beige Crystalline PowderPeso molecular:192.17Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Fórmula:C10H16O8Pureza:99.2% - >99.99%Cor e Forma:SolidPeso molecular:264.23FX1
CAS:<p>FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).</p>Fórmula:C14H9ClN2O4S2Pureza:97.59%Cor e Forma:SolidPeso molecular:368.82SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Fórmula:C12H12ClN3OPureza:99.56% - 99.92%Cor e Forma:SolidPeso molecular:249.69Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Fórmula:C23H19Cl2FN6OPureza:98.80%Cor e Forma:SolidPeso molecular:485.34Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Fórmula:C14H14N2O4SPureza:97.67% - >99.99%Cor e Forma:Yellow CrystallinePeso molecular:306.34α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Fórmula:C50H83NO21Pureza:98.42% - 99.94%Cor e Forma:White To Light YellowPeso molecular:1034.19MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Fórmula:C20H37N3O4Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:383.53Oleic acid
CAS:<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Fórmula:C18H34O2Pureza:97.14% - 99.91%Cor e Forma:Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Peso molecular:282.46GSK 872 hydrochloride
CAS:<p>GSK872 HCl（1346546-69-7 free base） (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.</p>Fórmula:C19H18ClN3O2S2Pureza:99%Cor e Forma:SolidPeso molecular:419.94AVN-944
CAS:<p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>Fórmula:C25H27N5O5Pureza:99.07% - ≥95%Cor e Forma:SolidPeso molecular:477.51GW 441756
CAS:<p>GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.</p>Fórmula:C17H13N3OPureza:97.73% - 99.8%Cor e Forma:SolidPeso molecular:275.3PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Fórmula:C24H25ClN6OPureza:99.13%Cor e Forma:SolidPeso molecular:448.95Ginkgolide B
CAS:<p>Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.</p>Fórmula:C20H24O10Pureza:98.66% - 99.81%Cor e Forma:White Crystal PowderPeso molecular:424.4Toyocamycin
CAS:<p>Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (</p>Fórmula:C12H13N5O4Pureza:98.1% - 98.17%Cor e Forma:SolidPeso molecular:291.26trans-Chalcone
CAS:<p>trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as</p>Fórmula:C15H12OPureza:99.89%Cor e Forma:SolidPeso molecular:208.26EPZ004777
CAS:<p>EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>Fórmula:C28H41N7O4Pureza:98.99% - 99.32%Cor e Forma:SolidPeso molecular:539.67BIBR 1532
CAS:<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Fórmula:C21H17NO3Pureza:98.49% - 98.90%Cor e Forma:SolidPeso molecular:331.36(Rac)-Benpyrine
CAS:<p>(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.</p>Fórmula:C16H16N6OPureza:98.44%Cor e Forma:SolidPeso molecular:308.34Tyrphostin AG 879
CAS:<p>Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.</p>Fórmula:C18H24N2OSPureza:99.05%Cor e Forma:SolidPeso molecular:316.46Rapanone
CAS:<p>Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.</p>Fórmula:C19H30O4Pureza:99.56%Cor e Forma:SolidPeso molecular:322.44HS-173
CAS:<p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>Fórmula:C21H18N4O4SPureza:99.33% - 99.64%Cor e Forma:SolidPeso molecular:422.46S55746 hydrochloride
CAS:<p>S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.</p>Fórmula:C43H43ClN4O6Pureza:98%Cor e Forma:SolidPeso molecular:747.28PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Fórmula:C19H15F3O5Pureza:99.78%Cor e Forma:SolidPeso molecular:380.31Alofanib
CAS:<p>Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.</p>Fórmula:C19H15N3O6SPureza:99.53% - 99.81%Cor e Forma:SolidPeso molecular:413.4Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Cor e Forma:Off-White To Light Yellow PowdPeso molecular:958.22
