CAS 81-81-2: (±)-Warfarin

Description: (±)-Warfarin is a synthetic anticoagulant commonly used in the prevention and treatment of thromboembolic disorders. It functions by inhibiting vitamin K epoxide reductase, which is essential for the synthesis of vitamin K-dependent clotting factors in the liver. This compound exists as a racemic mixture of two enantiomers, R and S, with the S-enantiomer being significantly more potent as an anticoagulant. Warfarin is characterized by its relatively low solubility in water, but it is soluble in organic solvents, which facilitates its formulation in various pharmaceutical preparations. The substance has a molecular formula of C19H16O4 and a molecular weight of approximately 308.34 g/mol. Its pharmacokinetics involve oral administration, with a delayed onset of action due to the time required for existing clotting factors to diminish. Warfarin is subject to significant interindividual variability in dosing due to factors such as genetic polymorphisms, dietary vitamin K intake, and interactions with other medications, necessitating careful monitoring of coagulation parameters during therapy.

Formula: C₁₉H₁₆O₄

InChI: InChI=1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3

InChI key: InChIKey=PJVWKTKQMONHTI-UHFFFAOYSA-N

SMILES: O=C1OC=2C=CC=CC2C(O)=C1C(C=3C=CC=CC3)CC(=O)C

Synonyms:

• (.+-.)-Warfarin
• (.+-.)-Warfarin-alcohol
• (RS)-Warfarin
• 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
• 3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
• 3-(α-Acetonylbenzyl)-4-hydroxycoumarin
• 3-(α-Phenyl-β-acetylethyl)-4-hydroxy-coumarin
• 3-(α-Phenyl-β-acetylethyl)-4-hydroxycoumarin
• 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
• 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
• <span class="text-smallcaps">DL</span>-3-(α-Acetonylbenzyl)-4-hydroxycoumarin
• Athrombine-K
• Benzopyran(2H-1)-2-One, 4-Hydroxy-3-(3-Oxo-1- Phenylbutyl)-
• Brumolin
• Circuvit
• Co-Rax
• Compound 42
• Coumadin
• Coumafen
• Coumafene
• Coumaphen
• Coumarin, 3-(α-acetonylbenzyl)-4-hydroxy-
• Coumefene
• DL-3-(α-Acetonylbenzyl)-4-hydroxycoumarin
• Dethmor
• Kumader
• Kumadu
• Kumatox
• Martefarin
• Nsc 59813
• Ratron
• Ratron G
• Rodafarin
• Rodafarin C
• Rodex
• Temus W
• Vampirinip II
• Vampirinip III
• W.A.R.F. 42
• WARF compound 42
• Warf 5
• Warf5
• Warfarin acid
• Warfarina
• Warfarine
• Zoocoumarin
• rac-Warfarin
• 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-

Warfarin Sodium (contains Isopropyl Alcohol)

CAS: 129-06-6 81-81-2

• Formula: C₁₉H₁₅NaO₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 330.31

Warfarin

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Purity: 99.4%
• Color and Shape: White
• Molecular weight: 308.10486

Warfarin RS

CAS: 81-81-2

• Formula: C₁₀H₁₆O₄
• Molecular weight: 200.2316

Warfarin sodium clathrate CRS

CAS: 81-81-2

• Color and Shape: Crystalline Powder. White. Powder.

Warfarin

CAS: 81-81-2

Aromatic lactones used as drugs

• Formula: C₁₉H₁₆O₄
• Color and Shape: White Colorless Crystals
• Molecular weight: 308.33 g/mol

Warfarin

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Purity: 98.0 - 102.0 % (anhydrous basis)
• Color and Shape: White crystalline powder
• Molecular weight: 308.33

Warfarin

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Color and Shape: Off-White Solid
• Molecular weight: 308.34

Warfarin 100 µg/mL in Acetonitrile

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Color and Shape: Single Solution
• Molecular weight: 308.33

Warfarin

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Color and Shape: Neat
• Molecular weight: 308.33

Warfarin

CAS: 81-81-2

• Formula: C₁₉H₁₆O₄
• Color and Shape: Neat
• Molecular weight: 308.33

Rodenticides Mixture 248 100 µg/mL in Acetonitrile

CAS: 28772-56-7 3691-35-8 56073-07-5 56073-10-0 81-81-282-66-6

• Formula: C₃₁H₂₃BrO₃
• Color and Shape: Mixture
• Molecular weight: 523.42

LC PestiMix 9 10 µg/mL in Acetonitrile

CAS: 1003318-67-9 1031756-98-5 104273-71-4 105779-78-0 1072957-71-1 1101132-67-5 1207727-04-5 121451-02-3 1220411-29-9 1228284-64-7 1229654-66-3 123572-88-3 1255734-28-1 1263133-33-0 130561-48-7 135186-78-6 1352994-67-2 1383809-87-7 1390661-72-9 140163-89-9 1417782-03-6 1472649-01-6 147411-69-6 1486617-22-4 156963-66-5 158237-07-1 162320-67-4 168088-61-7 173662-97-0 188489-07-8 200509-41-7 221205-90-9 224049-04-1 238410-11-2 256412-89-2 283159-90-0 330459-31-9 337458-27-2 352010-68-5 366815-39-6 42835-25-6 447399-55-5 473278-76-1 473798-59-3 494793-67-8 500207-04-5 517875-34-2 56073-07-5 5836-29-3 68049-83-2 688046-61-9 704886-18-0 799247-52-2 81-81-281-82-3 81334-34-1 81777-95-9 82692-44-2 847749-37-5 850881-70-8 862588-11-2 874195-61-6 874967-67-6 875915-78-9 881685-58-1 882182-49-2 902760-40-1 907204-31-3 911499-62-2 915972-17-7 926914-55-8 943831-98-9

• Color and Shape: Mixture

Warfarin

CAS: 81-81-2

Applications Coumarin anticoagulant. Marketed as the racemate; the S-(-)-form is the more potent isomer. Anticoagulant. …

• Formula: C₁₉H₁₆O₄
• Color and Shape: Neat
• Molecular weight: 308.33

Warfarin - 90%

CAS: 81-81-2

Please enquire for more information about Warfarin - 90% including the price, delivery time and …

• Formula: C₁₉H₁₆O₄
• Purity: Min. 95%
• Color and Shape: White Slightly Brown Clear Liquid
• Molecular weight: 308.33 g/mol