Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(117 products)
- EGFR(581 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2379 products of "Angiogenesis"
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AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formula:C19H14FN3O3SPurity:98.00% - 99.12%Color and Shape:SolidMolecular weight:383.4BMS-986142
CAS:BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).Formula:C32H30F2N4O4Purity:99.44% - 99.76%Color and Shape:SolidMolecular weight:572.6Ref: TM-T5138
1mg105.00€2mg165.00€5mg289.00€10mg447.00€25mg715.00€50mg964.00€100mg1,243.00€200mg1,693.00€1mL*10mM (DMSO)358.00€Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purity:99.81% - >99.99%Color and Shape:SolidMolecular weight:487.53BMS-2
CAS:BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formula:C25H16F2N4O3Purity:98.33%Color and Shape:SolidMolecular weight:458.42Ref: TM-T8326
1mg67.00€2mg88.00€5mg148.00€10mg230.00€25mg430.00€50mg622.00€100mg898.00€1mL*10mM (DMSO)170.00€Gefitinib-based PROTAC 3
CAS:Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Formula:C47H57ClFN7O8SPurity:97.29% - 98.25%Color and Shape:SolidMolecular weight:934.51CL-387785
CAS:CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formula:C18H13BrN4OPurity:99.56% - 99.62%Color and Shape:SolidMolecular weight:381.23SUN11602
CAS:SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formula:C26H37N5O2Purity:99.36%Color and Shape:SolidMolecular weight:451.6Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Ref: TM-T6961
1mg39.00€5mg84.00€10mg130.00€25mg193.00€50mg261.00€100mg411.00€200mg605.00€1mL*10mM (DMSO)84.00€Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purity:97.51% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52Agerafenib
CAS:Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Formula:C24H22F3N5O5Purity:95.78% - 99.23%Color and Shape:SolidMolecular weight:517.46Ref: TM-T2070
1mg39.00€5mg93.00€10mg124.00€25mg219.00€50mg358.00€100mg530.00€200mg757.00€1mL*10mM (DMSO)90.00€N-Desethylsunitinib hydrochloride
CAS:N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formula:C20H24ClFN4O2Purity:99.42%Color and Shape:SolidMolecular weight:406.88PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.362-(1,8-naphthyridin-2-yl)phenol
CAS:2-NP is a STAT1 enhancer.Formula:C14H10N2OPurity:99.33% - 99.82%Color and Shape:SolidMolecular weight:222.24Ref: TM-T2168
5mg57.00€10mg90.00€25mg177.00€50mg281.00€100mg444.00€200mg647.00€500mg982.00€1mL*10mM (DMSO)63.00€LDN-212854
CAS:LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formula:C25H22N6Purity:98% - 98.71%Color and Shape:SolidMolecular weight:406.48Ref: TM-T1900
1mg47.00€2mg62.00€5mg92.00€10mg172.00€25mg294.00€50mg439.00€100mg660.00€200mg945.00€1mL*10mM (DMSO)102.00€R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purity:99.27% - 99.84%Color and Shape:SolidMolecular weight:312.3Ref: TM-T3185
1mg37.00€2mg49.00€5mg79.00€10mg117.00€25mg207.00€50mg311.00€100mg462.00€500mg973.00€1mL*10mM (DMSO)87.00€Ibrutinib
CAS:Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Formula:C25H24N6O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:440.5Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6RG13022
CAS:RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Formula:C16H14N2O2Purity:98.38%Color and Shape:SolidMolecular weight:266.29Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formula:C28H32N4O3·xClHColor and Shape:SolidMidostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€1mL*10mM (DMSO)90.00€MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33Ref: TM-T4296
1mg60.00€2mg89.00€5mg167.00€10mg260.00€25mg439.00€50mg605.00€100mg802.00€200mg1,099.00€1mL*10mM (DMSO)170.00€TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44Ref: TM-T16996
1mg93.00€2mg117.00€5mg178.00€10mg295.00€25mg595.00€50mg795.00€100mg1,071.00€200mg1,468.00€1mL*10mM (DMSO)203.00€Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99Ref: TM-T22436
1mg92.00€2mg128.00€5mg178.00€10mg268.00€25mg439.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)243.00€OICR-9429
CAS:OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.Formula:C29H32F3N5O3Purity:97.07% - 99.93%Color and Shape:SolidMolecular weight:555.59Ref: TM-T6916
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg177.00€50mg295.00€100mg475.00€1mL*10mM (DMSO)92.00€(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46Ref: TM-T21503
1mg43.00€2mg56.00€5mg93.00€10mg113.00€25mg200.00€50mg330.00€100mg480.00€1mL*10mM (DMSO)90.00€AZD4547
CAS:AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formula:C26H33N5O3Purity:99.37% - 99.88%Color and Shape:SolidMolecular weight:463.57Ref: TM-T1948
2mg37.00€5mg50.00€10mg59.00€25mg84.00€50mg107.00€100mg147.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)52.00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formula:C14H13NO5Purity:98.06%Color and Shape:Yellow To Tan PowderMolecular weight:275.26Ref: TM-T4185
1mg42.00€2mg55.00€5mg93.00€10mg152.00€25mg330.00€50mg492.00€100mg707.00€1mL*10mM (DMSO)90.00€Regorafenib mesylate
CAS:Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.Formula:C22H19ClF4N4O6SColor and Shape:SolidMolecular weight:578.92A 83-01 sodium salt
CAS:A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.Formula:C25H19N5NaSColor and Shape:SolidMolecular weight:444.51Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95ODM-203
CAS:ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormula:C26H21F2N5O2SPurity:99.85%Color and Shape:SolidMolecular weight:505.54Ibrutinib deacryloylpiperidine
CAS:Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formula:C17H13N5OPurity:99.47%Color and Shape:SolidMolecular weight:303.32Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formula:C27H32ClN5O5Purity:98% - 99.63%Color and Shape:SolidMolecular weight:542.03Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5Ref: TM-T6091
1mg49.00€2mg63.00€5mg90.00€10mg170.00€25mg334.00€50mg512.00€100mg737.00€500mg1,521.00€1mL*10mM (DMSO)108.00€NVP-AEW541
CAS:NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormula:C27H29N5OPurity:98.7% - 99.86%Color and Shape:SolidMolecular weight:439.55Acalabrutinib
CAS:Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formula:C26H23N7O2Purity:98.94% - 99.64%Color and Shape:SolidMolecular weight:465.51Ref: TM-T3626
5mg44.00€10mg57.00€25mg78.00€50mg90.00€100mg144.00€200mg215.00€500mg355.00€1mL*10mM (DMSO)48.00€Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Formula:C23H21N7OPurity:98.54% - 99.74%Color and Shape:SolidMolecular weight:411.46Ref: TM-T6101
1mg38.00€2mg49.00€5mg81.00€10mg97.00€25mg170.00€50mg259.00€100mg416.00€200mg617.00€1mL*10mM (DMSO)88.00€SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purity:99.3% - 99.87%Color and Shape:SolidMolecular weight:507.51Ref: TM-T5194
1mg40.00€5mg84.00€10mg97.00€25mg180.00€50mg269.00€100mg430.00€500mg998.00€1mL*10mM (DMSO)87.00€A-443654
CAS:A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formula:C24H23N5OPurity:98.04% - 99.51%Color and Shape:SolidMolecular weight:397.47Ref: TM-T14072
1mg87.00€5mg178.00€10mg289.00€25mg537.00€50mg822.00€100mg1,234.00€200mg1,665.00€500mg2,457.00€1mL*10mM (DMSO)203.00€Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Ref: TM-T6345
1mg34.00€5mg60.00€10mg73.00€25mg142.00€50mg253.00€100mg424.00€200mg605.00€1mL*10mM (DMSO)63.00€NVP-BHG712
CAS:NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormula:C26H20F3N7OPurity:97.32% - 98.63%Color and Shape:SolidMolecular weight:503.48Ref: TM-T6348
1mg34.00€5mg74.00€10mg105.00€25mg200.00€50mg371.00€100mg557.00€200mg790.00€1mL*10mM (DMSO)84.00€PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66Ref: TM-T6177
1mg35.00€5mg74.00€10mg94.00€25mg138.00€50mg198.00€100mg296.00€200mg427.00€1mL*10mM (DMSO)89.00€FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purity:99.74%Color and Shape:SolidMolecular weight:358.39Ref: TM-T6012
1mg34.00€2mg46.00€5mg70.00€10mg105.00€25mg215.00€50mg304.00€100mg427.00€200mg587.00€1mL*10mM (DMSO)79.00€UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purity:99.52%Color and Shape:SolidMolecular weight:400.91Ref: TM-T2056L
1mg84.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)185.00€Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.90%Color and Shape:SolidMolecular weight:554.64Ref: TM-T4485
1mg46.00€2mg59.00€5mg96.00€10mg130.00€25mg215.00€50mg309.00€100mg444.00€200mg655.00€1mL*10mM (DMSO)104.00€ZINC13466751
CAS:ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formula:C20H21N5O2Purity:99.8%Color and Shape:SolidMolecular weight:363.41PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg37.00€2mg50.00€5mg63.00€10mg94.00€25mg146.00€50mg210.00€100mg294.00€1mL*10mM (DMSO)52.00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83Ref: TM-T1792L
5mg34.00€10mg46.00€25mg65.00€50mg94.00€100mg133.00€200mg197.00€500mg329.00€1mL*10mM (DMSO)55.00€Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purity:96.17% - 99.85%Color and Shape:SolidMolecular weight:557.04RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63Vactosertib
CAS:Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formula:C22H18FN7Purity:98.85% - 99.81%Color and Shape:SolidMolecular weight:399.42JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ibuprofen Lysine
CAS:Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formula:C19H32N2O4Purity:99.26%Color and Shape:CoaMolecular weight:352.47BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formula:C23H29N7O2Purity:97.98%Color and Shape:SolidMolecular weight:435.52Ref: TM-T9192
1mg46.00€5mg90.00€10mg152.00€25mg264.00€50mg398.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)100.00€(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurity:99.24%Color and Shape:SolidMolecular weight:386.45Ref: TM-T10626
1mg44.00€2mg57.00€5mg93.00€10mg120.00€25mg215.00€50mg313.00€100mg439.00€200mg628.00€1mL*10mM (DMSO)92.00€2,4-DPD
CAS:2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)Formula:C11H13NO4Purity:99.74%Color and Shape:Yellow Solid CrystallineMolecular weight:223.23Silymarin
CAS:Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formula:C25H22O10Purity:98%Color and Shape:Yellow And Brown PowderMolecular weight:482.441PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34Ref: TM-T1661
2mgTo inquire5mg33.00€10mg49.00€25mg55.00€50mg64.00€100mg88.00€500mg147.00€1mL*10mM (DMSO)50.00€Tucatinib
CAS:Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formula:C26H24N8O2Purity:99.05% - 99.96%Color and Shape:SolidMolecular weight:480.52Ref: TM-T2364
1g1,071.00€2mg34.00€5mg50.00€10mg74.00€25mg117.00€50mg177.00€100mg333.00€500mg782.00€1mL*10mM (DMSO)82.00€Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formula:C23H21Cl2FN4O3Purity:98.69% - 99.78%Color and Shape:SolidMolecular weight:491.34SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurity:98.07%Color and Shape:SolidMolecular weight:821.12Ref: TM-T5349
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg200.00€50mg333.00€100mg495.00€1mL*10mM (DMSO)102.00€NCGC00262650
CAS:NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:98% - 98.21%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg44.00€5mg65.00€10mg110.00€25mg178.00€50mg304.00€100mg482.00€200mg687.00€1mL*10mM (DMSO)71.00€CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formula:C29H39ClN6O6SColor and Shape:SolidMolecular weight:635.17BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.96Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg42.00€2mg52.00€5mg74.00€10mg101.00€25mg175.00€50mg268.00€100mg409.00€200mg573.00€500mg888.00€1mL*10mM (DMSO)81.00€BMS817378
CAS:BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).Formula:C24H18ClF2N4O7PPurity:>99.99%Color and Shape:SolidMolecular weight:578.85Theliatinib tartrate
CAS:Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Formula:C29H32N6O8Color and Shape:SolidMolecular weight:592.6MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39Ref: TM-T6886
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg245.00€50mg358.00€100mg537.00€1mL*10mM (DMSO)90.00€(Rac)-JBJ-04-125-02
CAS:(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Formula:C29H26FN5O3SPurity:97.57%Color and Shape:SolidMolecular weight:543.61Ref: TM-T8872
1mg100.00€5mg205.00€10mg334.00€25mg567.00€50mg807.00€100mg1,099.00€1mL*10mM (DMSO)249.00€Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formula:C21H27N5O3Purity:99.14% - 99.93%Color and Shape:SolidMolecular weight:397.47TAS0728
CAS:TAS0728 is a HER2 inhibitor, with antitumor activityFormula:C26H32N8O3Purity:97.78%Color and Shape:SolidMolecular weight:504.58Ref: TM-T7819
1mg48.00€5mg105.00€10mg166.00€25mg304.00€50mg485.00€100mg658.00€200mg888.00€1mL*10mM (DMSO)111.00€WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purity:99.21%Color and Shape:SolidMolecular weight:297.31Blu-782
CAS:Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:C31H42N6O4Purity:99.51%Color and Shape:SolidMolecular weight:562.7FGFR2-IN-3 hydrochloride
CAS:FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formula:C28H25ClFN7O2Color and Shape:SolidMolecular weight:546.0AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purity:99.62%Color and Shape:SolidMolecular weight:496.36Ref: TM-T4249
2mg34.00€5mg46.00€10mg62.00€25mg94.00€50mg167.00€100mg265.00€200mg385.00€1mL*10mM (DMSO)49.00€Tranilast
CAS:Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormula:C18H17NO5Purity:99.67% - >99.99%Color and Shape:White With Light Yellow Crystalline PowderMolecular weight:327.33Ref: TM-T2690
5mg43.00€10mg55.00€25mg66.00€50mg93.00€100mg119.00€200mg175.00€500mg298.00€1mL*10mM (DMSO)55.00€PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurity:99.98%Color and Shape:SolidMolecular weight:340.42Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Color and Shape:SolidMolecular weight:454.95SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purity:99.57%Color and Shape:SolidMolecular weight:323.35JCN037
CAS:JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formula:C16H11BrFN3O2Purity:99.5%Color and Shape:SolidMolecular weight:376.18Tolimidone
CAS:Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
Formula:C11H10N2O2Purity:99.85% - 99.85%Color and Shape:SolidMolecular weight:202.21TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formula:C32H36N8O3Purity:97.16% - 98.12%Color and Shape:SolidMolecular weight:580.68R-268712
CAS:R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formula:C20H18FN5OPurity:99.61%Color and Shape:SolidMolecular weight:363.39Ref: TM-T16708
1mg44.00€5mg93.00€10mg130.00€25mg250.00€50mg378.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)92.00€Vadimezan
CAS:Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formula:C17H14O4Purity:97.38% - 99.8%Color and Shape:SolidMolecular weight:282.29Ref: TM-T6273
2mg39.00€5mg58.00€10mg93.00€25mg172.00€50mg268.00€100mg401.00€200mg580.00€1mL*10mM (DMSO)89.00€Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purity:98.37% - 99.84%Color and Shape:Off-White SolidMolecular weight:467.92PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48
