Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Isolongifolene
CAS:<p>Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and</p>Formula:C15H24Purity:90.13% - 99.46%Color and Shape:Colorless Or Light Yellow LiquidMolecular weight:204.35ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Formula:C29H31ClFN5O5Purity:98.99%Color and Shape:SolidMolecular weight:584.04Trifloxystrobin
CAS:<p>Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.</p>Formula:C20H19F3N2O4Purity:99.49%Color and Shape:SolidMolecular weight:408.37LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Formula:C20H20Cl2N4O4Purity:98.02% - 98.4%Color and Shape:SolidMolecular weight:451.3QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42Bardoxolone
CAS:<p>Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.</p>Formula:C31H41NO4Purity:97.9% - 98.97%Color and Shape:SolidMolecular weight:491.66Thalidomide-O-C4-NH2 hydrochloride
CAS:<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Formula:C17H20ClN3O5Purity:98.33%Color and Shape:SolidMolecular weight:381.81Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Formula:C18H29NO3Purity:99.61% - ≥95%Color and Shape:White CrystalMolecular weight:307.43Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Formula:C19H16ClN2NaO3Color and Shape:SolidMolecular weight:378.79Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Formula:C24H28N2O9Purity:97.46%Color and Shape:SolidMolecular weight:488.49PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.39MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39SKLB-163
CAS:<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Formula:C18H16ClN3O2S2Purity:99.23%Color and Shape:SolidMolecular weight:405.92Fasentin
CAS:<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Formula:C11H9ClF3NO2Purity:99.95%Color and Shape:SolidMolecular weight:279.64Mitoxantrone diacetate
CAS:<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Formula:C26H36N4O10Color and Shape:SolidMolecular weight:564.592ONO-8130
CAS:<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Formula:C25H28N2O5S2Purity:97.82%Color and Shape:SolidMolecular weight:500.63Fedratinib
CAS:<p>Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.</p>Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68Chelerythrine
CAS:<p>1.</p>Formula:C21H18NO4Purity:98.36%Color and Shape:SolidMolecular weight:348.37Dimethyl malonate
CAS:<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Formula:C5H8O4Purity:≥95%Color and Shape:LiquidMolecular weight:132.11Itanapraced
CAS:<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Formula:C16H11Cl2FO2Purity:98% - 99.79%Color and Shape:SolidMolecular weight:325.16Tofacitinib Citrate
CAS:<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49Siremadlin
CAS:<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Formula:C26H24Cl2N6O4Purity:99.30% - 99.76%Color and Shape:SolidMolecular weight:555.41Meloxicam sodium
CAS:<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Formula:C14H12N3NaO4S2Color and Shape:SolidMolecular weight:373.383'-Hydroxypterostilbene
CAS:<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formula:C16H16O4Purity:98.25% - 99.19%Color and Shape:SolidMolecular weight:272.3Benzoylpaeoniflorin
CAS:<p>1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.</p>Formula:C30H32O12Purity:95.86% - 97.28%Color and Shape:SolidMolecular weight:584.57Cinchonine monohydrochloride hydrate
CAS:<p>Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.</p>Formula:C19H25ClN2O2Color and Shape:SolidMolecular weight:348.87Ulinastatin
CAS:<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Formula:C13H16O3Purity:98%Color and Shape:SolidMolecular weight:220.10994Droxinostat
CAS:<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Formula:C11H14ClNO3Purity:99.83%Color and Shape:SolidMolecular weight:243.69RG7112
CAS:<p>RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.</p>Formula:C38H48Cl2N4O4SPurity:99.66% - 99.9%Color and Shape:SolidMolecular weight:727.788-Bromo-cAMP sodium salt
CAS:<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Formula:C10H10BrN5NaO6PPurity:98% - 99.94%Color and Shape:Off-White PowderMolecular weight:430.08C5 Lenalidomide
CAS:<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Formula:C13H13N3O3Purity:99.4%Color and Shape:SolidMolecular weight:259.26Kinetin riboside
CAS:<p>Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)</p>Formula:C15H17N5O5Purity:98.17%Color and Shape:White SolidMolecular weight:347.33Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formula:C35H41ClN6O4Purity:99.52%Color and Shape:SolidMolecular weight:645.19Flupentixol dihydrochloride
CAS:<p>Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.</p>Formula:C23H27Cl2F3N2OSPurity:98.76% - >99.99%Color and Shape:White Or Off-White SolidMolecular weight:507.43Shield-1
CAS:<p>Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.</p>Formula:C42H56N2O10Purity:99.08%Color and Shape:SolidMolecular weight:748.9Tazemetostat
CAS:<p>Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.</p>Formula:C34H44N4O4Purity:98.24% - ≥95%Color and Shape:SolidMolecular weight:572.74Nerol
CAS:<p>Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias</p>Formula:C10H18OPurity:98.59%Color and Shape:Colorless Oily Liquid LiquidMolecular weight:154.25Ricolinostat
CAS:<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formula:C24H27N5O3Purity:97.17% - 99.76%Color and Shape:SolidMolecular weight:433.5Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formula:C15H16ClN3O5Purity:98.56%Color and Shape:SolidMolecular weight:353.76Sodium Demethylcantharidate
CAS:<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>Formula:C8H9O5·NaPurity:99.66% - ≥98%Color and Shape:SolidMolecular weight:208.14BAY 61-3606 HCl
CAS:<p>BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.</p>Formula:C20H19ClN6O3Color and Shape:SolidMolecular weight:426.86FB23-2
CAS:<p>FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).</p>Formula:C18H15Cl2N3O3Purity:97.29% - ≥95%Color and Shape:SolidMolecular weight:392.24Thalidomide-O-amido-C6-NH2 TFA
CAS:<p>Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based</p>Formula:C46H53F6N8O16Purity:95.16%Color and Shape:SolidMolecular weight:1087.95ICCB280
CAS:<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formula:C23H18N2O4Purity:98.04%Color and Shape:SolidMolecular weight:386.4Phenoxyethanol
CAS:<p>Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.</p>Formula:C8H10O2Purity:99.47%Color and Shape:Clear To Practically Clear Colourless LiquidMolecular weight:138.16NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42Lenaldekar
CAS:<p>Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.</p>Formula:C18H14N4Purity:97.73%Color and Shape:SolidMolecular weight:286.33Hederacolchiside A1
CAS:<p>Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.</p>Formula:C47H76O16Purity:98.76% - 99.92%Color and Shape:SolidMolecular weight:897.1Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34
