Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Anisomycin
CAS:<p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>Formula:C14H19NO4Purity:98.33% - 99.81%Color and Shape:White Crystalline SolidMolecular weight:265.3A-419259
CAS:<p>A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.</p>Formula:C29H34N6OPurity:99.48%Color and Shape:SolidMolecular weight:482.62Volasertib
CAS:<p>Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.</p>Formula:C34H50N8O3Purity:98% - 99.72%Color and Shape:SolidMolecular weight:618.81FIN56
CAS:<p>FIN56 is a specific inducer of ferroptosis.</p>Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Calycosin
CAS:<p>Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).</p>Formula:C16H12O5Purity:99.91% - >99.99%Color and Shape:White PowderMolecular weight:284.26Ro-3306
CAS:<p>RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.</p>Formula:C18H13N3OS2Purity:97.67% - 99.79%Color and Shape:SolidMolecular weight:351.452-tert-Butyl-1,4-benzoquinone
CAS:<p>TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.</p>Formula:C10H12O2Purity:97.19%Color and Shape:SolidMolecular weight:164.2Ziyuglycoside I
CAS:<p>Ziyuglycoside I (Gouguside 7) has anti-inflammatory activity, could be used as an active ingredient for cosmetics.</p>Formula:C41H66O13Purity:98.987% - ≥95%Color and Shape:SolidMolecular weight:766.95PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formula:C18H21Cl3N4OPurity:99.5%Color and Shape:SolidMolecular weight:415.75Coniferaldehyde
CAS:<p>Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes. Coniferaldehyde has a role as an antifungal agent and a plant metabolite.</p>Formula:C10H10O3Purity:96.35% - 99.96%Color and Shape:SolidMolecular weight:178.18Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.5NSC 73150
CAS:<p>6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.</p>Formula:C12H12N4O2Purity:99.84%Color and Shape:SolidMolecular weight:244.25FR 180204
CAS:<p>FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.</p>Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Formula:C23H19Cl2FN6OPurity:98.80%Color and Shape:SolidMolecular weight:485.34Pectolinarin
CAS:<p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>Formula:C29H34O15Purity:98% - 99.79%Color and Shape:SolidMolecular weight:622.57Tauroursodeoxycholate
CAS:<p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>Formula:C26H45NO6SPurity:98.77% - 99.93%Color and Shape:White SolidMolecular weight:499.7PEAQX
CAS:<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Formula:C17H17BrN3O5PPurity:98% - 99.9%Color and Shape:SolidMolecular weight:454.21GSK 3 Inhibitor IX
CAS:<p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>Formula:C16H10BrN3O2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:356.17ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94AR42
CAS:<p>AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).</p>Formula:C18H20N2O3Purity:98.46% - 98.96%Color and Shape:SolidMolecular weight:312.36BTZO-1
CAS:<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Formula:C13H8N2OSPurity:99.46%Color and Shape:SolidMolecular weight:240.28Emricasan
CAS:<p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>Formula:C26H27F4N3O7Purity:98.13% - 99%Color and Shape:SolidMolecular weight:569.5Aloperine
CAS:<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.361400W dihydrochloride
CAS:<p>1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).</p>Formula:C10H17Cl2N3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:250.17Amifostine thiol dihydrochloride
CAS:<p>Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.</p>Formula:C5H16Cl2N2SPurity:>99.99%Color and Shape:SolidMolecular weight:207.165Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Formula:C29H32N6O4SPurity:98% - 99.42%Color and Shape:SolidMolecular weight:560.67Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Formula:C50H71N13O12Purity:95% - >99.99%Color and Shape:SolidMolecular weight:1046.18L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formula:C5H9NO4Purity:99.14% - 99.55%Color and Shape:White Solid CrystallineMolecular weight:147.13GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formula:C15H18O8Purity:98.81% - 99.92%Color and Shape:White SolidMolecular weight:326.3Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formula:C8H16O2Purity:97.78% - 99%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47Ipatasertib
CAS:<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Formula:C24H32ClN5O2Purity:98.28% - 99.21%Color and Shape:SolidMolecular weight:458Caudatin
CAS:<p>Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.</p>Formula:C28H42O7Purity:98.83% - 99.9%Color and Shape:SolidMolecular weight:490.63Sulforaphane
CAS:<p>Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formula:C6H11NOS2Purity:95% - 99.79%Color and Shape:Light Yellow LiquidMolecular weight:177.29Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68TVB-3166
CAS:<p>TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).</p>Formula:C24H24N4OPurity:99.53% - 99.57%Color and Shape:SolidMolecular weight:384.47Larotrectinib sulfate
CAS:<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formula:C21H22F2N6O2·H2O4SPurity:98.62% - 99.76%Color and Shape:SolidMolecular weight:526.51Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:<p>Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase</p>Formula:C5H14Cl2N4O3Purity:99.12% - 99.84%Color and Shape:SolidMolecular weight:249.10NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58ZZW-115 hydrochloride
CAS:<p>ZZW-115 hydrochloride inhibits the activity of NUPR1.</p>Formula:C24H34Cl3F3N4SPurity:99.97%Color and Shape:SolidMolecular weight:573.97Chromium picolinate
CAS:<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Formula:C18H12CrN3O6Purity:99.64%Color and Shape:Violet-Red Crystalline PowderMolecular weight:418.30RIPGBM
CAS:<p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>Formula:C26H21FN2O3Purity:99.45%Color and Shape:SolidMolecular weight:428.458-Prenylnaringenin
CAS:<p>8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,</p>Formula:C20H20O5Purity:98.26% - 99.46%Color and Shape:SolidMolecular weight:340.37Soyasapogenol B
CAS:<p>Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.</p>Formula:C30H50O3Purity:99.51% - 99.81%Color and Shape:SolidMolecular weight:458.72Cynaroside
CAS:<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formula:C21H20O11Purity:98% - >99.99%Color and Shape:SolidMolecular weight:448.38Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Formula:C15H20O2Purity:99.02% - 99.66%Color and Shape:Crystalline PowderMolecular weight:232.32LASSBio-1135
CAS:<p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>Formula:C18H14N4Purity:99.09%Color and Shape:SolidMolecular weight:286.33Pitavastatin calcium
CAS:<p>Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.</p>Formula:C50H46CaF2N2O8Purity:98.89% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:880.98Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:<p>Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-</p>Formula:C17H21ClN4O5Purity:97.13%Color and Shape:SolidMolecular weight:396.83
