Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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Selonsertib HCl
CAS:Selonsertib (GS-4997) is an oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic, and anti-fibrotic effects.Formula:C24H25ClFN7OColor and Shape:SolidMolecular weight:481.96EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purity:99.48%Color and Shape:SolidMolecular weight:644.4Ref: TM-T7955
1mg87.00€2mg114.00€5mg177.00€10mg260.00€25mg447.00€50mg620.00€100mg875.00€200mg1,161.00€1mL*10mM (DMSO)263.00€NVP-CGM097
CAS:NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).Formula:C38H47ClN4O4Purity:98.77%Color and Shape:SolidMolecular weight:659.26Ref: TM-TQ0231
1mg82.00€5mg195.00€10mg324.00€25mg492.00€50mg647.00€100mg893.00€1mL*10mM (DMSO)284.00€Amifostine thiol dihydrochloride
CAS:Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.Formula:C5H16Cl2N2SPurity:>99.99%Color and Shape:SolidMolecular weight:207.165Coniferaldehyde
CAS:Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes. Coniferaldehyde has a role as an antifungal agent and a plant metabolite.Formula:C10H10O3Purity:97.71% - 99.96%Color and Shape:SolidMolecular weight:178.18(Z)-Mirin
CAS:(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.Formula:C10H8N2O2SPurity:99.67% - 99.76%Color and Shape:SolidMolecular weight:220.25Ref: TM-T3134
5mg55.00€10mg87.00€25mg140.00€50mg226.00€100mg416.00€200mg542.00€500mg872.00€1mL*10mM (DMSO)55.00€Calcium D-saccharate tetrahydrate
CAS:Calcium D-saccharate tetrahydrate (Calcium D-saccharate tetrahydrate) is an oxidized non-cyclic hexose sugar.Formula:C6H16CaO12Purity:98%Color and Shape:White SolidMolecular weight:320.26SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.351,4-Naphthoquinone
CAS:1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.Formula:C10H6O2Purity:99.24% - 99.56%Color and Shape:SolidMolecular weight:158.15K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:277.34ELR510444
CAS:ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.Formula:C19H16N2O2S2Purity:97.67% - 98.69%Color and Shape:SolidMolecular weight:368.47Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formula:C34H31ClN8O5SPurity:99.36% - 99.52%Color and Shape:SolidMolecular weight:699.18Ref: TM-T5440
1mg47.00€5mg92.00€10mg147.00€25mg264.00€50mg409.00€100mg592.00€500mg1,224.00€1mL*10mM (DMSO)166.00€SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38Ref: TM-T1724
1mg39.00€2mg50.00€5mg79.00€10mg120.00€25mg258.00€50mg408.00€100mg588.00€1mL*10mM (DMSO)79.00€Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.
Formula:C8H10O4Purity:98%Color and Shape:Needles From Petroleum Ether Slight Yellow PowderMolecular weight:170.16Capmatinib
CAS:Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Formula:C23H17FN6OPurity:99.24%Color and Shape:SolidMolecular weight:412.42Ref: TM-T1963
5mg48.00€10mg63.00€25mg78.00€50mg90.00€100mg124.00€200mg158.00€500mg255.00€1mL*10mM (DMSO)50.00€Pralatrexate
CAS:Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folateFormula:C23H23N7O5Purity:94.32% - 99.59%Color and Shape:SolidMolecular weight:477.47Ref: TM-T6120
1mg35.00€2mg52.00€5mg74.00€10mg97.00€25mg160.00€50mg197.00€100mg344.00€200mgTo inquire1mL*10mM (DMSO)79.00€Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.732-Chloroadenosine
CAS:2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectivelyFormula:C10H12ClN5O4Purity:99.23%Color and Shape:White PowderMolecular weight:301.69L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formula:C8H18N2O3SPurity:97.07% - ≥98%Color and Shape:White Fine PowderMolecular weight:222.31ABT-737
CAS:ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43C25-140
CAS:C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Formula:C26H31N7OPurity:98.81%Color and Shape:SolidMolecular weight:457.57Ziyuglycoside II
CAS:1.Formula:C35H56O8Purity:99.52% - ≥95%Color and Shape:SolidMolecular weight:604.814,5-Dicaffeoylquinic acid
CAS:1.Formula:C25H24O12Purity:98.86% - ≥95%Color and Shape:SolidMolecular weight:516.45Ref: TM-T2S1158
1mg43.00€5mg84.00€10mg109.00€25mg172.00€50mg250.00€100mg326.00€200mg522.00€1mL*10mM (DMSO)102.00€Tubastatin A
CAS:Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formula:C20H21N3O2Purity:97.22% - 99.51%Color and Shape:SolidMolecular weight:335.4Ref: TM-T1966
10mg46.00€25mg60.00€50mg74.00€100mg105.00€200mg160.00€500mg259.00€1mL*10mM (DMSO)44.00€Isosilybin A
CAS:Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (Formula:C25H22O10Purity:98.79%Color and Shape:SolidMolecular weight:482.44CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formula:C23H27N3O5S2Purity:99.46% - 99.91%Color and Shape:SolidMolecular weight:489.61Ref: TM-T4309
1mg34.00€2mg49.00€5mg74.00€10mg109.00€25mg178.00€50mg284.00€100mg434.00€1mL*10mM (DMSO)81.00€TPEN
CAS:TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.Formula:C26H28N6Purity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:424.54SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purity:97.73%Color and Shape:SolidMolecular weight:432.56Ref: TM-T9073
1mg34.00€2mg49.00€5mg73.00€10mg108.00€25mg203.00€50mg306.00€100mg459.00€1mL*10mM (DMSO)89.00€G-749
CAS:G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.Formula:C25H25BrN6O2Purity:98.32% - 99.60%Color and Shape:SolidMolecular weight:521.41SPP-86
CAS:SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.Formula:C16H15N5Purity:99.53%Color and Shape:SolidMolecular weight:277.32Ref: TM-T16923
1mg46.00€5mg90.00€10mg144.00€25mg281.00€50mg447.00€100mg650.00€500mg1,369.00€1mL*10mM (DMSO)90.00€GSK2982772
CAS:GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formula:C20H19N5O3Purity:99.27% - 99.31%Color and Shape:SolidMolecular weight:377.4PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.36SZL P1-41
CAS:SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.Formula:C24H24N2O3SPurity:99.60% - 99.87%Color and Shape:SolidMolecular weight:420.52MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91HS-1793
CAS:HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.Formula:C16H12O3Purity:98.16% - 99.82%Color and Shape:SolidMolecular weight:252.26Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formula:C10H16O8Purity:99.2% - 99.92%Color and Shape:SolidMolecular weight:264.23INH1
CAS:INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.Formula:C18H16N2OSPurity:99.80%Color and Shape:SolidMolecular weight:308.4BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formula:C35H34N2O7Purity:98.43%Color and Shape:SolidMolecular weight:594.7Ref: TM-T8470
1mg58.00€5mg124.00€10mg177.00€25mg299.00€50mg424.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)172.00€ASK1-IN-2
CAS:ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.Formula:C19H17FN6OPurity:98.79%Color and Shape:SolidMolecular weight:364.38GSK583
CAS:GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).Formula:C20H19FN4O2SPurity:98.68% - 99.81%Color and Shape:SolidMolecular weight:398.45Ref: TM-T3537
1mg50.00€2mg65.00€5mg96.00€10mg120.00€25mg205.00€50mg286.00€100mg394.00€200mg573.00€1mL*10mM (DMSO)92.00€Indinavir sulfate
CAS:Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
Formula:C36H49N5O8SPurity:99.75% - >99.99%Color and Shape:White PowderMolecular weight:711.87KY-05009
CAS:KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).Formula:C18H16N4O2SPurity:99.89%Color and Shape:SolidMolecular weight:352.41Ref: TM-T11793
5mg48.00€10mg67.00€25mg111.00€50mg161.00€100mg231.00€200mg335.00€1mL*10mM (DMSO)49.00€Capmatinib 2HCl
CAS:Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.Formula:C23H19Cl2FN6OPurity:98.80%Color and Shape:SolidMolecular weight:485.34Ref: TM-T4260
2mg34.00€5mg49.00€10mg64.00€25mg84.00€50mg92.00€100mg126.00€500mg303.00€1mL*10mM (DMSO)58.00€CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48Tomatine
CAS:Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formula:C50H83NO21Purity:98.42% - 99.94%Color and Shape:White To Light YellowMolecular weight:1034.19MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formula:C20H37N3O4Purity:98% - ≥98%Color and Shape:SolidMolecular weight:383.53Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormula:C20H26O3Purity:99.26% - 99.86%Color and Shape:Off-White To Yellow SolidMolecular weight:314.42BC-1258
CAS:BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.Formula:C22H22N4S2Purity:97.48% - 99.64%Color and Shape:SolidMolecular weight:406.57B-AP15
CAS:B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.Formula:C22H17N3O6Purity:91.43% - 98.77%Color and Shape:SolidMolecular weight:419.39PS 48
CAS:PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).Formula:C17H15ClO2Purity:99.96% - ≥95%Color and Shape:SolidMolecular weight:286.75
