Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6039 products of "Apoptosis"
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SKI II
CAS:SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.Formula:C15H11ClN2OSPurity:99.34% - 99.93%Color and Shape:SolidMolecular weight:302.78STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formula:C25H23N3O4SPurity:98.66%Color and Shape:SolidMolecular weight:461.532-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Formula:C15H12O2Purity:99.6%Color and Shape:SolidMolecular weight:224.25Pracinostat
CAS:Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oralFormula:C20H30N4O2Purity:99.15% - 99.67%Color and Shape:SolidMolecular weight:358.48Dinaciclib
CAS:Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).Formula:C21H28N6O2Purity:98.21% - 99.75%Color and Shape:SolidMolecular weight:396.49Nafamostat mesylate
CAS:Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitisFormula:C19H17N5O2·2CH4O3SPurity:97.36% - 99.76%Color and Shape:Tan To Pale Orange SolidMolecular weight:539.58KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Formula:C20H20N2O3SPurity:99.77%Color and Shape:SolidMolecular weight:368.45BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Formula:C20H18N6O3Purity:98.72%Color and Shape:SolidMolecular weight:390.4Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:97.7% - 99.99%Color and Shape:SolidMolecular weight:510.61Sacubitril/Valsartan
CAS:Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for treatment of hypertension and heart failure.Formula:C48H55N6O8Na3·5H2OPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:957.99Etretinate
CAS:Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.Formula:C23H30O3Purity:97.89%Color and Shape:Crystals Crystalline SolidMolecular weight:354.48CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Formula:C28H38N4O3Purity:97.83%Color and Shape:SolidMolecular weight:478.63ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Formula:C29H31ClFN5O5Purity:98.99%Color and Shape:SolidMolecular weight:584.04LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purity:98.02% - 98.4%Color and Shape:SolidMolecular weight:451.3QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42Thalidomide-O-C4-NH2 hydrochloride
CAS:Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.Formula:C17H20ClN3O5Purity:98.33%Color and Shape:SolidMolecular weight:381.81Thalidomide-PEG4-Propargyl
CAS:Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.Formula:C24H28N2O9Purity:97.46%Color and Shape:SolidMolecular weight:488.49MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39Mitoxantrone diacetate
CAS:Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).Formula:C26H36N4O10Color and Shape:SolidMolecular weight:564.592Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68Dimethyl malonate
CAS:Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.Formula:C5H8O4Purity:≥95%Color and Shape:LiquidMolecular weight:132.11Itanapraced
CAS:Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).Formula:C16H11Cl2FO2Purity:98% - 99.79%Color and Shape:SolidMolecular weight:325.16Siremadlin
CAS:Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.Formula:C26H24Cl2N6O4Purity:98.98% - 99.76%Color and Shape:SolidMolecular weight:555.41Meloxicam sodium
CAS:Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].Formula:C14H12N3NaO4S2Color and Shape:SolidMolecular weight:373.383'-Hydroxypterostilbene
CAS:3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Formula:C16H16O4Purity:98.25% - 99.19%Color and Shape:SolidMolecular weight:272.3Benzoylpaeoniflorin
CAS:1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.Formula:C30H32O12Purity:95.86% - 97.28%Color and Shape:SolidMolecular weight:584.57Cinchonine monohydrochloride hydrate
CAS:Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.Formula:C19H25ClN2O2Color and Shape:SolidMolecular weight:348.87RG7112
CAS:RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.Formula:C38H48Cl2N4O4SPurity:99.66% - 99.9%Color and Shape:SolidMolecular weight:727.788-Bromo-cAMP sodium salt
CAS:8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.Formula:C10H10BrN5NaO6PPurity:98% - 99.94%Color and Shape:Off-White PowderMolecular weight:430.08C5 Lenalidomide
CAS:C5 Lenalidomide is an chemical weith inconclusive biological activity.Formula:C13H13N3O3Purity:99.4%Color and Shape:SolidMolecular weight:259.26Kinetin riboside
CAS:Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)Formula:C15H17N5O5Purity:98.17%Color and Shape:White SolidMolecular weight:347.33Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Formula:C24H25ClFN5O2Purity:99.4% - 99.72%Color and Shape:SolidMolecular weight:469.94Shield-1
CAS:Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.Formula:C42H56N2O10Purity:99.08%Color and Shape:SolidMolecular weight:748.9Tazemetostat
CAS:Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.Formula:C34H44N4O4Purity:98.24% - ≥95%Color and Shape:SolidMolecular weight:572.74Nerol
CAS:Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmiasFormula:C10H18OPurity:98.59%Color and Shape:Colorless Oily Liquid LiquidMolecular weight:154.25Ricolinostat
CAS:<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formula:C24H27N5O3Purity:97.17% - 99.76%Color and Shape:SolidMolecular weight:433.5Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formula:C15H16ClN3O5Purity:98.56%Color and Shape:SolidMolecular weight:353.76Sodium Demethylcantharidate
CAS:Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Formula:C8H9O5·NaPurity:99.66% - ≥98%Color and Shape:SolidMolecular weight:208.14BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formula:C20H19ClN6O3Color and Shape:SolidMolecular weight:426.86FB23-2
CAS:FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).Formula:C18H15Cl2N3O3Purity:97.29% - ≥95%Color and Shape:SolidMolecular weight:392.24Phenoxyethanol
CAS:Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.Formula:C8H10O2Purity:99.47%Color and Shape:Clear To Practically Clear Colourless LiquidMolecular weight:138.16Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34ZYN57939
CAS:ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.Formula:C28H27N7O2SPurity:99.81%Color and Shape:SolidMolecular weight:525.62Trametinib (DMSO solvate)
CAS:Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)Formula:C28H29FIN5O5SPurity:99.71% - 99.92%Color and Shape:SolidMolecular weight:693.53Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purity:99.58% - >99.99%Color and Shape:White Crystalline SolidMolecular weight:285.69Glycochenodeoxycholic acid sodium salt
CAS:GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.Formula:C26H42NNaO5Purity:95.48% - 99.82%Color and Shape:SolidMolecular weight:471.61Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormula:C42H56F2N8O6Purity:97.08% - ≥95%Color and Shape:SolidMolecular weight:806.94
