Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6064 products of "Apoptosis"
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Thalidomide-O-C4-NH2 hydrochloride
CAS:Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.Formula:C17H20ClN3O5Purity:98.33%Color and Shape:SolidMolecular weight:381.81Bardoxolone
CAS:Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.Formula:C31H41NO4Purity:97.9% - 98.97%Color and Shape:SolidMolecular weight:491.66AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purity:99.62%Color and Shape:SolidMolecular weight:496.36Ref: TM-T4249
2mg35.00€5mg48.00€10mg65.00€25mg99.00€50mg170.00€100mg280.00€200mg406.00€1mL*10mM (DMSO)51.00€(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purity:99.14%Color and Shape:SolidMolecular weight:275.34Mycophenolic acid sodium
CAS:Mycophenolic acid sodium inhibits IMPDH with EC50 of 0.24 μM, has antiviral, immunosuppressive, antiangiogenic, and antitumor properties.Formula:C17H19NaO6Color and Shape:SolidMolecular weight:342.323WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2SW106065
CAS:SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.Formula:C10H8N2OSPurity:99.97%Color and Shape:SolidMolecular weight:204.25Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Formula:C14H12N2O4Purity:99.48%Color and Shape:SolidMolecular weight:272.26Ref: TM-T40503
1mg69.00€5mg153.00€10mg221.00€25mg379.00€50mg532.00€100mg718.00€200mg969.00€1mL*10mM (DMSO)137.00€8-Prenylnaringenin
CAS:8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,Formula:C20H20O5Purity:98.26% - 99.46%Color and Shape:SolidMolecular weight:340.37Ref: TM-TN1146
1mg144.00€5mg354.00€10mg520.00€25mg825.00€50mg1,111.00€100mg1,491.00€1mL*10mM (DMSO)437.00€Enzastaurin 2HCl
CAS:Enzastaurin (DB-102/LY317615) is a macrocyclic bisindolemaleimide inhibiting protein kinase C beta to reduce tumor blood supply.Formula:C32H31Cl2N5O2Color and Shape:SolidMolecular weight:588.53QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42Ref: TM-T6204
1mg43.00€2mg57.00€5mg93.00€10mg140.00€25mg188.00€50mg329.00€100mg490.00€200mg710.00€1mL*10mM (DMSO)93.00€JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purity:98.02% - 98.4%Color and Shape:SolidMolecular weight:451.3Ref: TM-T37314
1mg52.00€5mg111.00€10mg173.00€25mg298.00€50mg464.00€100mg747.00€200mg1,017.00€1mL*10mM (DMSO)124.00€ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurity:99.36% - 99.56%Color and Shape:SolidMolecular weight:407.49Ref: TM-T2463
1mg39.00€2mg50.00€5mg72.00€10mg106.00€25mg210.00€50mg339.00€100mg543.00€1mL*10mM (DMSO)74.00€McMMAF
CAS:McMMAF is a protective group-conjugated MMAF.Formula:C49H76N6O11Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:925.16Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43SKI V
CAS:<p>SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),</p>Formula:C15H10O4Purity:98.78%Color and Shape:SolidMolecular weight:254.24LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Formula:C14H13N3O2SPurity:99.97% - >99.99%Color and Shape:SolidMolecular weight:287.342BAct
CAS:2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress responseFormula:C19H16ClF3N4O3Purity:97.97% - 99.04%Color and Shape:SolidMolecular weight:440.8Lycorine
CAS:Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.Formula:C16H17NO4Purity:98.60% - 99.95%Color and Shape:SolidMolecular weight:287.31BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurity:99.46%Color and Shape:SolidMolecular weight:463.32Ref: TM-T6776
1mg38.00€5mg84.00€10mg116.00€25mg187.00€50mg279.00€100mg406.00€200mg565.00€1mL*10mM (DMSO)87.00€MGH-CP1
CAS:MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.Formula:C20H24N4OSPurity:98.66%Color and Shape:SolidMolecular weight:368.5Ref: TM-T9032
2mg40.00€5mg60.00€10mg87.00€25mg187.00€50mg329.00€100mg535.00€200mg748.00€1mL*10mM (DMSO)71.00€VTP50469 mesylate
CAS:VTP-50469: oral MeninMLL1 inhibitor for MLL/NPM1c+ leukemia; kills affected cell lines.Formula:C33H51FN6O7S2Color and Shape:SolidMolecular weight:726.9244Alisertib Sodium
CAS:Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis.Formula:C27H19ClFN4NaO4Purity:99.77%Color and Shape:SolidMolecular weight:540.91Trifloxystrobin
CAS:Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.Formula:C20H19F3N2O4Purity:99.49%Color and Shape:SolidMolecular weight:408.37Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurity:99.53% - 99.86%Color and Shape:SolidMolecular weight:499.7MFCD01917484
CAS:MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.Formula:C14H15NO3SPurity:98.09%Color and Shape:SolidMolecular weight:277.34ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purity:99.92%Color and Shape:SolidMolecular weight:405.41Ref: TM-T9697
1mg90.00€5mg215.00€10mg321.00€25mg582.00€50mg873.00€100mg1,216.00€1mL*10mM (DMSO)236.00€ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Formula:C29H31ClFN5O5Purity:98.99%Color and Shape:SolidMolecular weight:584.04Erdafitinib
CAS:Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formula:C25H30N6O2Purity:97.00% - 99.36%Color and Shape:SolidMolecular weight:446.54Rasagiline Mesylate
CAS:Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.Formula:C13H17NO3SPurity:99.33%Color and Shape:White PowderMolecular weight:267.34AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formula:C8H18N3O8PPurity:99.44%Color and Shape:SolidMolecular weight:315.22JQ-1 (carboxylic acid)
CAS:JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)Formula:C19H17ClN4O2SPurity:99.14% - 99.9%Color and Shape:SolidMolecular weight:400.88(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formula:C20H22O7Purity:99.88%Color and Shape:SolidMolecular weight:374.38A-1331852
CAS:A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.Formula:C38H38N6O3SPurity:98.15% - >99.99%Color and Shape:SolidMolecular weight:658.81Ref: TM-T6749
1mg51.00€2mg71.00€5mg115.00€10mg177.00€25mg368.00€50mg550.00€100mg787.00€1mL*10mM (DMSO)166.00€Isolongifolene
CAS:Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, andFormula:C15H24Purity:90.13% - 99.46%Color and Shape:Colorless Or Light Yellow LiquidMolecular weight:204.35CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Formula:C28H38N4O3Purity:97.83%Color and Shape:SolidMolecular weight:478.63Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formula:CH10Cl2Na2O10P2Purity:98%Color and Shape:SolidMolecular weight:360.92(R)-(-)-Gossypol acetic acid
CAS:(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.Formula:C30H30O8·C2H4O2Purity:98.88% - 99.5%Color and Shape:SolidMolecular weight:578.61Ref: TM-T6396
1g1,359.00€2mg39.00€5mg57.00€10mg87.00€25mg170.00€50mg283.00€100mg464.00€500mg1,008.00€Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purity:99.04% - 99.3%Color and Shape:SolidMolecular weight:785.01Ref: TM-T3916
1mg35.00€5mg69.00€10mg88.00€25mg144.00€50mg205.00€100mg303.00€500mg735.00€1mL*10mM (DMSO)97.00€Carnosic acid
CAS:Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.Formula:C20H28O4Purity:98.31% - 99.5%Color and Shape:Yellow PowderMolecular weight:332.43Taccalonolide A
CAS:Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it isFormula:C36H46O14Purity:98.16% - 99.4%Color and Shape:SolidMolecular weight:702.74NVP-HSP990
CAS:NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).Formula:C20H18FN5O2Purity:98.03% - 99.32%Color and Shape:SolidMolecular weight:379.39Psoralen
CAS:<p>Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.</p>Formula:C11H6O3Purity:99.3% - 99.87%Color and Shape:Crystals From Ether Crystalline SolidMolecular weight:186.16R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurity:98.64% - 99.8%Color and Shape:SolidMolecular weight:380.77Ref: TM-T4637
1mg35.00€2mg46.00€5mg66.00€10mg96.00€25mg207.00€50mg283.00€100mg464.00€200mg658.00€1mL*10mM (DMSO)74.00€NVP-CGM097
CAS:NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).Formula:C38H47ClN4O4Purity:98.77%Color and Shape:SolidMolecular weight:659.26Ref: TM-TQ0231
1mg87.00€5mg207.00€10mg341.00€25mg520.00€50mg682.00€100mg944.00€1mL*10mM (DMSO)300.00€[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formula:C19H28O3Purity:97.01%Color and Shape:SolidMolecular weight:304.42Ref: TM-T5430
1mg96.00€5mg208.00€10mg359.00€25mg592.00€50mg837.00€100mg1,121.00€1mL*10mM (DMSO)230.00€BIO-acetoxime
CAS:<p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>Formula:C18H12BrN3O3Purity:97.15%Color and Shape:SolidMolecular weight:398.21
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