Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6064 products of "Apoptosis"
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Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Alisertib Sodium
CAS:Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis.Formula:C27H19ClFN4NaO4Purity:99.77%Color and Shape:SolidMolecular weight:540.91AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
CAS:Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFormula:C22H16N2OPurity:99.18%Color and Shape:SolidMolecular weight:324.38Ref: TM-T9129
1mg52.00€5mg107.00€10mg158.00€25mg259.00€50mg374.00€100mg523.00€200mg710.00€1mL*10mM (DMSO)111.00€(R)-(-)-Gossypol acetic acid
CAS:(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.Formula:C30H30O8·C2H4O2Purity:98.88% - 99.5%Color and Shape:SolidMolecular weight:578.61Ref: TM-T6396
1g1,359.00€2mg39.00€5mg57.00€10mg87.00€25mg170.00€50mg283.00€100mg464.00€500mg1,008.00€Etalocib
CAS:Etalocib (LY293111) is a potent diaryl ether inhibitor blocking LTB4 receptor and 5'-lipoxygenase, with antineoplastic properties.Formula:C33H33FO6Purity:98.21%Color and Shape:SolidMolecular weight:544.6Ref: TM-T22358
1mg71.00€5mg160.00€10mg226.00€25mg419.00€50mg615.00€100mg883.00€200mg1,188.00€1mL*10mM (DMSO)192.00€Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formula:C24H16F3NO4Purity:99.16% - 99.93%Color and Shape:SolidMolecular weight:439.383-Dehydrotrametenolic acid
CAS:3-Dehydrotrametenolic acid is a potential anticancer agent against H-ras transformed tumor and a promising candidate for a new type of insulin-sensitizing drug.Formula:C30H46O3Purity:98.5% - 99.25%Color and Shape:SolidMolecular weight:454.68Ref: TM-T5S0620
1mg48.00€5mg97.00€10mg156.00€25mg255.00€50mg368.00€100mg505.00€200mg692.00€1mL*10mM (DMSO)114.00€K34C
CAS:K34C is a selective inhibitor of Integrin α5β1, which inhibits cell survival and migration, promotes apoptosis, inhibits invasion.Formula:C26H29N3O4Purity:99.66%Color and Shape:SolidMolecular weight:447.53Pilaralisib analogue
CAS:Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.Formula:C21H16N6O2S2Purity:99.3% - 99.72%Color and Shape:SolidMolecular weight:448.52Ref: TM-T2377
2mg38.00€5mg55.00€10mg88.00€25mg139.00€50mg216.00€100mg374.00€200mg485.00€1mL*10mM (DMSO)87.00€Ginkgolide B
CAS:Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.Formula:C20H24O10Purity:98.66% - 99.81%Color and Shape:White Crystal PowderMolecular weight:424.40Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormula:C18H16N2O3Purity:97.69%Color and Shape:SolidMolecular weight:308.33Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Red Crystalline PowderMolecular weight:450.61Toyocamycin
CAS:<p>Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (</p>Formula:C12H13N5O4Purity:98.1% - 98.17%Color and Shape:SolidMolecular weight:291.26Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurity:99% - 99.02%Color and Shape:SolidMolecular weight:285.37Adalimumab
CAS:Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.Purity:95% - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:145.4 kDaAT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43trans-Chalcone
CAS:trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively asFormula:C15H12OPurity:99.89%Color and Shape:SolidMolecular weight:208.26Icaritin
CAS:Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formula:C21H20O6Purity:97.69% - 99.76%Color and Shape:SolidMolecular weight:368.38EPZ004777
CAS:EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formula:C28H41N7O4Purity:98.99% - 99.32%Color and Shape:SolidMolecular weight:539.67Solasodine
CAS:Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.Formula:C27H43NO2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:413.64Se-Methylselenocysteine
CAS:Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.Formula:C4H9NO2SePurity:99.49% - 99.87%Color and Shape:White To Slightly Yellow PowderMolecular weight:182.08PTC-028
CAS:<p>PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected.</p>Formula:C19H12F5N5Purity:97.61% - 98.12%Color and Shape:SolidMolecular weight:405.32Ref: TM-T16680
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg283.00€50mg469.00€100mg687.00€500mg1,444.00€Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormula:C8H16O2·C8H15O2·NaPurity:99.87%Color and Shape:A White Powder With A Characteristic OdorMolecular weight:310.41Ref: TM-T6474
10mg39.00€25mg55.00€50mg79.00€100mg116.00€200mg188.00€500mg335.00€1mL*10mM (DMSO)55.00€Angiotensin II human acetate
CAS:Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.Formula:C52H75N13O14Purity:98.89% - 99.78%Color and Shape:SolidMolecular weight:1106.2Tamibarotene
CAS:Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFormula:C22H25NO3Purity:98.55% - 99.73%Color and Shape:Crystalline SolidMolecular weight:351.44Ref: TM-T6694
1g369.00€10mg47.00€25mg64.00€50mg79.00€100mg97.00€200mg153.00€500mg249.00€1mL*10mM (DMSO)47.00€BIBR 1532
CAS:<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Formula:C21H17NO3Purity:98.49% - 98.90%Color and Shape:SolidMolecular weight:331.36PCI-34051
CAS:<p>PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).</p>Formula:C17H16N2O3Purity:97.219% - 98.29%Color and Shape:SolidMolecular weight:296.32MI-136
CAS:MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formula:C23H21F3N6SPurity:98.63% - 99.12%Color and Shape:SolidMolecular weight:470.51Ref: TM-T6889
1mg47.00€5mg87.00€10mg147.00€25mg279.00€50mg472.00€100mg730.00€200mg1,017.00€1mL*10mM (DMSO)97.00€(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formula:C16H16N6OPurity:98.44%Color and Shape:SolidMolecular weight:308.34Ref: TM-T8692
1mg48.00€2mg65.00€5mg97.00€10mg160.00€25mg311.00€50mg467.00€100mg653.00€200mg924.00€1mL*10mM (DMSO)111.00€Tyrphostin AG 879
CAS:Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Formula:C18H24N2OSPurity:99.05%Color and Shape:SolidMolecular weight:316.46AGK2
CAS:<p>AGK2（IC50=3.5 μM） is an effective, and specific SIRT2 inhibitor.</p>Formula:C23H13Cl2N3O2Purity:98.68% - 99.17%Color and Shape:SolidMolecular weight:434.27Rapanone
CAS:Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.Formula:C19H30O4Purity:99.56%Color and Shape:SolidMolecular weight:322.44HS-173
CAS:<p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>Formula:C21H18N4O4SPurity:99.33% - 99.64%Color and Shape:SolidMolecular weight:422.46RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Formula:C22H17F2N2·CH3O4SPurity:99.72%Color and Shape:SolidMolecular weight:458.48Fidaxomicin
CAS:Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.Formula:C52H74Cl2O18Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:1058.04Ref: TM-T6194
1g437.00€10mg48.00€25mg59.00€50mg81.00€100mg124.00€200mg177.00€500mg283.00€1mL*10mM (DMSO)55.00€Leachianone A
CAS:Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.Formula:C26H30O6Purity:98.53% - 99.79%Color and Shape:SolidMolecular weight:438.51S55746 hydrochloride
CAS:S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.Formula:C43H43ClN4O6Purity:98%Color and Shape:SolidMolecular weight:747.28L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formula:C5H8NO4·NaPurity:99.93%Color and Shape:White Solid CrystallineMolecular weight:169.11Kevetrin hydrochloride
CAS:Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potentialFormula:C5H10ClN3SPurity:99.32% - 99.93%Color and Shape:SolidMolecular weight:179.67Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C15H20O3Purity:98.19% - 99.46%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:248.323-O-Acetyloleanolic acid
CAS:3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells.Formula:C32H50O4Purity:98% - 99.57%Color and Shape:SolidMolecular weight:498.74PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Formula:C19H15F3O5Purity:99.78%Color and Shape:SolidMolecular weight:380.31Alofanib
CAS:Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.Formula:C19H15N3O6SPurity:99.53% - 99.81%Color and Shape:SolidMolecular weight:413.4Citric acid
CAS:<p>Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits, a food additive and a natural preservative. High-Quality, Low-Cost!</p>Formula:C6H8O7Purity:98.88%Color and Shape:White Solid CrystallineMolecular weight:192.12Curcumol
CAS:Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.Formula:C15H24O2Purity:98.99% - 99.87%Color and Shape:SolidMolecular weight:236.35ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formula:C25H24N6O3Purity:99.25%Color and Shape:SolidMolecular weight:456.5Ref: TM-T6921
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg279.00€50mg462.00€100mg662.00€1mL*10mM (DMSO)96.00€Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Formula:C53H83NO14Purity:97.76% - 99.78%Color and Shape:Off-White To Light Yellow PowdMolecular weight:958.22Galgravin
CAS:<p>Galgravin combats inflammation, safeguards neurons, promotes neurite growth, and resists Abeta25-35 and MPP+ toxicity.</p>Formula:C22H28O5Purity:99.75% - 99.88%Color and Shape:SolidMolecular weight:372.45Ursonic Acid
CAS:Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton.Formula:C30H46O3Purity:98.90% - >99.99%Color and Shape:SolidMolecular weight:454.68
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