Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(141 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(138 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(14 products)
- Survivin(14 products)
- TNF(89 products)
- c-RET(56 products)
- p53(63 products)
Show 6 more subcategories
Found 5887 products of "Apoptosis"
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Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Formula:C10H7Cl2N3O·HClPurity:99.58%Color and Shape:Off-White PowderMolecular weight:292.55Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Formula:C24H30N6O2Purity:98.87%Color and Shape:SolidMolecular weight:434.53RX-3117
CAS:RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.Formula:C10H12FN3O4Purity:97.46%Color and Shape:SolidMolecular weight:257.22Clovamide
CAS:<p>Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T.</p>Formula:C18H17NO7Purity:97.12% - 97.68%Color and Shape:SolidMolecular weight:359.33Galgravin
CAS:<p>Galgravin combats inflammation, safeguards neurons, promotes neurite growth, and resists Abeta25-35 and MPP+ toxicity.</p>Formula:C22H28O5Purity:99.75% - 99.88%Color and Shape:SolidMolecular weight:372.45Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Formula:C15H12O3Purity:98.07% - 99.18%Color and Shape:SolidMolecular weight:240.25PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formula:C18H39NO3Purity:99.81%Color and Shape:SolidMolecular weight:317.51RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Alofanib
CAS:Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.Formula:C19H15N3O6SPurity:99.53% - 99.81%Color and Shape:SolidMolecular weight:413.4Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Formula:C19H15F3O5Purity:99.78%Color and Shape:SolidMolecular weight:380.31S55746 hydrochloride
CAS:<p>S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.</p>Formula:C43H43ClN4O6Purity:98%Color and Shape:SolidMolecular weight:747.28Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Formula:C21H23N3O2Purity:97.2% - 99.81%Color and Shape:Yellow SolidMolecular weight:349.43Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Formula:C20H24O5Purity:97.00%Color and Shape:SolidMolecular weight:344.4Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formula:C10H16O8Purity:99.2% - 99.92%Color and Shape:SolidMolecular weight:264.23Helichrysetin
CAS:<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Formula:C16H14O5Purity:96.32% - ≥95%Color and Shape:SolidMolecular weight:286.28ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59Benidipine hydrochloride
CAS:<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.03Atractylenolide III
CAS:<p>Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.</p>Formula:C15H20O3Purity:99.53% - 99.82%Color and Shape:SolidMolecular weight:248.32Mimosine
CAS:L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.Formula:C8H10N2O4Purity:99.2% - 99.84%Color and Shape:Crystals From Water SolidMolecular weight:198.18
