Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(268 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3904 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Ceftriaxone
CAS:Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.Formula:C18H18N8O7S3Purity:96.08%Color and Shape:SolidMolecular weight:554.586-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical andFormula:C11H15N5O4Color and Shape:SolidMolecular weight:281.27CDK-IN-12
CAS:CDK-IN-12 (Example 20), a CDK inhibitor, effectively inhibits CDK4/6, demonstrating IC50 values below 20 nM [1].Formula:C26H29FN6OSColor and Shape:SolidMolecular weight:492.61Endo-1,4-β-xylanase
CAS:Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.Color and Shape:SolidMethylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Color and Shape:Odour SolidhuATN-658
huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.Color and Shape:Odour LiquidCCT241533 dihydrochloride
CAS:Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.Formula:C23H29Cl2FN4O4Color and Shape:SolidMolecular weight:515.41m7GpppUmpG
CAS:m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.Formula:C31H42N12O26P4Color and Shape:SolidMolecular weight:1122.636-Methoxypurine-9-β-D-(3-methoxy riboside)
6-Methoxypurine riboside is a purine analog with anti-lymphoma activity via DNA synthesis inhibition and apoptosis induction.Formula:C12H16N4O5Color and Shape:SolidMolecular weight:296.28Ribonuclease T1
CAS:Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.
Color and Shape:SolidFarletuzumab
CAS:Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.Purity:> 95%Color and Shape:LiquidMolecular weight:145.36 kDaSR15006
CAS:SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formula:C16H20ClN3O4SPurity:99.87%Color and Shape:SoildMolecular weight:385.87Garenoxacin
CAS:Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formula:C23H20F2N2O4Purity:98%Color and Shape:SolidMolecular weight:426.41HLB-0532259
CAS:HLB-0532259 is a PROTAC degrader that targets the degradation of Aurora-A and N-Myc. In non-MYCN amplified MCF-7 cells, it degrades Aurora-A with a DC50 of 20.2 nM, and in MYCN amplified SK-N-BE and Kelly cells, it degrades N-Myc with DC50 values of 179 nM and 229 nM, respectively. HLB-0532259 has demonstrated antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Formula:C40H44N8O7Color and Shape:SolidMolecular weight:748.8275'-O-DMT-ibu-dC
CAS:5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.Formula:C34H37N3O7Color and Shape:SolidMolecular weight:599.67LL-K8-22
LL-K8-22: potent CDK8/cyclin C degrader; DC50 ~2.5μM; hinders STAT1 phosphorylation; curbs E2F/MYC cancer pathways; for TNBC study.Formula:C37H43N5OColor and Shape:SolidMolecular weight:573.77JAMM protein inhibitor 2
CAS:JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.Formula:C21H26N2O2Purity:98.57%Color and Shape:SolidMolecular weight:338.44Ficellomycin
CAS:Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.Formula:C13H24N6O3Color and Shape:SolidMolecular weight:312.37dUTP trisodium
CAS:dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
Formula:C9H12N2Na3O14P3Purity:100.00%Color and Shape:SolidMolecular weight:534.09(E/Z)-THZ1 2HCl
CAS:THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.
Formula:C31H30Cl3N7O2Purity:99.51%Color and Shape:SolidMolecular weight:638.98KWR137
KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105RNase L ligand 1
RNase L ligand 1 (Compound F1-COOH) serves as a ligand for RNase L and is utilized in the synthesis of F1-RIBOTAC.Formula:C21H21Cl2NO3Color and Shape:SolidMolecular weight:406.302PROTAC CDK9 degrader-8
PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].Formula:C44H52Cl2N10O7Purity:98%Color and Shape:SolidMolecular weight:903.855-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.Formula:C22H31N3O5SiColor and Shape:SolidMolecular weight:445.58CTP Synthetase-IN-1 Ammonium salt
CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infectionsFormula:C20H22F3N7O3S2Purity:99.97%Color and Shape:SolidMolecular weight:529.56MORF-627
CAS:MORF-627 is an orally active selective inhibitor of integrin αvβ6 (integrinαvβ6), with an IC50 of 9.2 nM as measured in a human serum ligand binding assay. It effectively inhibits αvβ6-mediated activation of TGF-β1 with an IC50 of 2.63 nM and suppresses SMAD2/3 phosphorylation, showing an IC50 of 8.3 nM. Additionally, MORF-627 ameliorates bleomycin-induced pulmonary fibrosis in mice.Formula:C31H40FN3O4Color and Shape:SolidMolecular weight:537.672'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium
2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits broad antitumor activity specifically targeting indolentFormula:C22H43FN7O7PColor and Shape:SolidMolecular weight:567.59FRα-targeting peptide C7
CAS:FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα), exhibiting specific binding capabilities to cells expressing FRα and potential for in vivo tumor targeting. This peptide is utilized in research for tumor diagnosis and therapy.Formula:C62H90N18O16SMolecular weight:1375.55PARP-1-IN-32
CAS:PARP-1-IN-32 (compound 15) is an inhibitor of poly (ADPribose) polymerase-1 (PARP-1), specifically designed for use in cancer research.Formula:C21H16N2O5Color and Shape:SolidMolecular weight:376.36dTAG Targeting Ligand 1
CAS:dTAG Targeting Ligand 1 (SUBSTITUTE SHEET 245) serves as a ligand for target proteins in PROTAC (Proteolysis Targeting Chimera) applications. It is used in the synthesis of PROTACs.Formula:C22H27N5O4Color and Shape:SolidMolecular weight:425.482'-Deoxy-2'-fluoro-l-uridine
CAS:2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.Formula:C9H11FN2O5Color and Shape:SolidMolecular weight:246.19Cy5-dATP
Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .
Formula:C47H58N7O19P3S2Color and Shape:SolidMolecular weight:1182.05Cdk2/Cyclin Inhibitory Peptide II
CAS:Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL), a CDK2 inhibitor, demonstrates dose-dependent cytotoxic effects on U2OS osteosarcoma cells [1].Formula:C110H200N48O25Color and Shape:SolidMolecular weight:2595.07Levomefolate magnesium
CAS:Levomefolate magnesium is the main active folate in food and plasma, essential for DNA synthesis and amino acid regulation, safe for use as a supplement.Formula:C20H23MgN7O6Color and Shape:SolidMolecular weight:481.74Anticancer agent 190
Anticancer agent 190 (compound 3e) is an inhibitor targeting KSP (Kinesin) and PI3Kδ, demonstrating efficacy against breast cancer.Formula:C21H13ClF2N2OSMolecular weight:414.04052Arg-Gly-Glu-Ser TFA
Arg-Gly-Glu-Ser TFA, an RGD-related peptide, serves as a control for evaluating the inhibitory activity of RGDS on fibrinogen binding to activated platelets.Formula:C18H30F3N7O10Color and Shape:SolidMolecular weight:561.47YRGDS Fibronectin Fragment
CAS:This is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets. It is RGD consisting of sequence.Formula:C24H36N8O10Purity:98%Color and Shape:SolidMolecular weight:596.592'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.Formula:C10H11FLi4N5O12P3Color and Shape:SolidMolecular weight:532.95'-O-TBDMS-N2-ibu-dG
CAS:5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.Formula:C20H33N5O5SiColor and Shape:SolidMolecular weight:451.592'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium), a purine nucleoside analog, exhibits extensive antitumor properties, particularly against indolentFormula:C13H34N9O15P3Color and Shape:SolidMolecular weight:649.38Zelavespib HCl
CAS:PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.Formula:C18H22ClIN6O2SPurity:99.45%Color and Shape:SoildMolecular weight:548.83c-Myc ligand 1
CAS:c-Mycligand 1 is a c-Myc inhibitor and functions as a ligand for target proteins in PROTAC (Proteolysis Targeting Chimeras). It is utilized in the synthesis of PROTAC c-Myc inhibitor 7.Formula:C13H10N2O2Molecular weight:226.23TTK/PLK1-IN-1
CAS:TTK/PLK1-IN-1 (Formula I) is a dual inhibitor of TTK (threonine tyrosine kinase) and PLK1 (polo-like kinase 1), with IC₅₀ values of 7 nM and 72 nM respectively.Formula:C30H33N7O2Purity:97.39%Color and Shape:SolidMolecular weight:523.63EC-1456
CAS:EC-1456 is a folate-microtubule targeting agent that exhibits significant antiproliferative activity against folate receptor (FR) positive tumors, including models resistant to anticancer drugs. EC-1456 is utilized in cancer research.Formula:C110H165N23O45S3Color and Shape:SolidMolecular weight:2625.81SP27
CAS:SP27, a selective PROTAC, degrades PLK4 with a DC50 of 19.5 nM and may be utilized in breast cancer research [1].Formula:C40H40F2N12O5Purity:98%Color and Shape:SolidMolecular weight:806.82αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Formula:C25H32F2N4O3Color and Shape:SolidMolecular weight:474.54Emofolin sodium
CAS:Emofolin sodium, a synthetic folate analogue, inhibits DNA/RNA/protein synthesis by blocking dihydrofolate reductase.Formula:C21H25N7Na2O6Purity:98%Color and Shape:SolidMolecular weight:517.45Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.Formula:C24H24N2O9Color and Shape:SolidMolecular weight:484.46T20-M
T20-M is a precursor peptide with strong binding affinity for UBE2C.Formula:C87H140N22O26SColor and Shape:SolidMolecular weight:1942.24DNA Gyrase-IN-10
DNA Gyrase-IN-10 is a potent inhibitor of DNA gyrase, exhibiting strong antibacterial activity. It effectively inhibits both Gram-positive and Gram-negative bacteria.Formula:C26H24BrFN6O3Molecular weight:566.10773CDK12-IN-2
CAS:CDK12-IN-2 selectively inhibits CDK12 (IC50: 52 nM) with minimal effect on CDK2, CDK7, and CDK9, useful for CDK12 research.
Formula:C32H32N6O2Purity:99.31%Color and Shape:SolidMolecular weight:532.642'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formula:C21H35FN2O5Color and Shape:SolidMolecular weight:414.51Ripasudil free base
CAS:Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.Formula:C15H18FN3O2SPurity:98%Color and Shape:SolidMolecular weight:323.39Ref: TM-T7492
1mg75.00€5mg150.00€10mg238.00€25mg530.00€50mg873.00€100mg1,459.00€1mL*10mM (DMSO)166.00€c-Myc inhibitor 5
DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.Formula:C30H46N12Color and Shape:SolidMolecular weight:574.771-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.Formula:C18H21N5O5Color and Shape:SolidMolecular weight:387.395'-ODMT cEt G Phosphoramidite (Amidite)
CAS:5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Formula:C46H56N7O9PColor and Shape:SolidMolecular weight:881.95Ac-dA Phosphoramidite
CAS:Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.Formula:C42H50N7O7PColor and Shape:SolidMolecular weight:795.878SD49-7
CAS:SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.Formula:C18H14N2O3Purity:99.91%Color and Shape:SoildMolecular weight:306.32Ref: TM-T67781
1mg57.00€5mg124.00€10mg178.00€25mg359.00€50mg520.00€100mg745.00€500mg1,485.00€1mL*10mM (DMSO)141.00€DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFormula:C19H17N5O5SColor and Shape:SolidMolecular weight:427.43HB-3-20
HB-3-20 induces the degradation of integrin αVβ5 on the cell surface. Transglutaminase 2 (TG2) specifically interacts with HB-3-20, exhibiting a catalytic efficiency (kcat/KM) of 0.16 μM^-1min^-1.Formula:C69H102N20O20Color and Shape:SolidMolecular weight:1531.67Tirandamycin A
Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.Formula:C22H27NO7Color and Shape:SolidMolecular weight:417.458c(phg-isoDGR-(NMe)k) TFA
C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].Formula:C29H42F3N9O9Color and Shape:SolidMolecular weight:717.69N7-Methyl-2'-O-(2-methoxyethyl) guanosine
N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formula:C14H21N5O6Color and Shape:SolidMolecular weight:355.356-Thioguanosine
CAS:6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.Formula:C10H13N5O4SPurity:97.05%Color and Shape:Yellow-Green PowderMolecular weight:299.31CDK6/9-IN-1
CAS:CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).Formula:C22H25ClN8OColor and Shape:SolidMolecular weight:452.95Nocarnickelamides B
Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.Formula:C29H42N6O9Color and Shape:Odour SolidMolecular weight:618.68IBU-DC Phosphoramidite
CAS:IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.Formula:C43H54N5O8PColor and Shape:SolidMolecular weight:799.906GS-443902 trisodium
CAS:GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.Formula:C12H16N5O13P3·xNaColor and Shape:SolidDeoxythymidine-5'-triphosphate
CAS:Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.Formula:C10H17N2O14P3Color and Shape:SolidMolecular weight:482.167Cytidine 5'-diphosphate trisodium salt
CAS:CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.Formula:C9H15N3Na3O11P2Purity:99.55%Color and Shape:White Crystalline PowderMolecular weight:472.15Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.Formula:C37H62N8O12S2Color and Shape:SolidMolecular weight:875.06Chk1-IN-6
CAS:Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.Formula:C16H18F3N7Color and Shape:SolidMolecular weight:365.3646-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity byFormula:C15H17N5O6Color and Shape:SolidMolecular weight:363.33IRE1α kinase-IN-6
CAS:IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC 50 value of 4.4 nM.Formula:C25H23Cl2FN6O3S2Color and Shape:SolidMolecular weight:609.52LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.532'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormula:C18H17ClF3N5O4Color and Shape:SolidMolecular weight:459.81α2β1 Integrin Ligand Peptide
CAS:The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellularFormula:C14H22N4O9Purity:98%Color and Shape:SolidMolecular weight:390.35LL-K12-18
LL-K12-18 is a dual-site molecular gel that enhances PPI between CDK12-DDB1 complexes thereby promoting the degradation of Cyclin K and anti-proliferation.Formula:C25H32Cl2N10OPurity:98.08% - 99.77%Color and Shape:SoildMolecular weight:559.495'-O-DMT-N4-Bz-2'-F-dC
CAS:5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.Formula:C37H34FN3O7Color and Shape:SolidMolecular weight:651.68CDK8-IN-12
CAS:CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.Formula:C21H20ClN3O2Purity:98.55% - 99.22%Color and Shape:SoildMolecular weight:381.86Ref: TM-T72048
1mg52.00€5mg101.00€10mg150.00€25mg250.00€50mg363.00€100mg509.00€200mg695.00€1mL*10mM (DMSO)116.00€Adenosine-2-carboxy methyl amide
Adenosine-2-carboxy methyl amide: a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis.Formula:C12H16N6O5Color and Shape:SolidMolecular weight:324.29GK13S
G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.Formula:C21H22N6O2Color and Shape:SolidMolecular weight:390.44UnyLinker 12 TEA
UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.Formula:C39H35NO10C6H15NColor and Shape:SolidMolecular weight:778.34655Psammaplin A
CAS:Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.Formula:C22H24Br2N4O6S2Color and Shape:SolidMolecular weight:664.38Viquidacin
CAS:NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.Formula:C25H29FN2O4S2Color and Shape:SolidMolecular weight:504.64JB-11 isethionate
CAS:JB-11 isethionate is a bioactive chemical.Formula:C21H29N5O7SColor and Shape:SolidMolecular weight:495.55Carboxy-pyridostatin
CAS:Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.
Formula:C35H34N10O7Color and Shape:SolidMolecular weight:706.71XT17
XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.Color and Shape:Odour SolidDSPE-PEG1000-iRGD
DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.Color and Shape:Odour SolidBSJ-03-204 triTFA
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring Palbociclib-based ligands for theFormula:C49H51F9N10O14Purity:98%Color and Shape:SolidMolecular weight:1174.97BLINK15
BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.Color and Shape:Odour SolidOdulimomab
CAS:Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.Color and Shape:LiquidLDV
CAS:α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.Formula:C48H70N10O12Purity:98%Color and Shape:SolidMolecular weight:979.138β,9α-Dihydroxylindan-4(5),7(11)-dien-8α,12-olide
CAS:8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, exhibits anti-LIMK1 activity and inhibits cell motility [1].Formula:C15H18O4Color and Shape:SolidMolecular weight:262.3CDK12-IN-4
CAS:CDK12-IN-4 is a pyrazolotriazine that inhibits CDK12 (IC50: 0.641 μM) with high ATP (2 mM) and spares CDK2/Cyclin E and CDK9/Cyclin T1 (IC50: >20 μM).Formula:C20H20F2N8OColor and Shape:SolidMolecular weight:426.432T-2513
CAS:T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.Formula:C25H27N3O5Color and Shape:SolidMolecular weight:449.507KGDS
CAS:KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].Formula:C15H27N5O8Color and Shape:SolidMolecular weight:405.4IV-361
CAS:IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1Formula:C23H32FN5O2SiColor and Shape:SolidMolecular weight:457.62516,16-dimethyl Prostaglandin A1
CAS:16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.Formula:C22H36O4Color and Shape:SolidMolecular weight:364.526Sp-dUTPαS tetrasodium
Sp-dUTPαS tetrasodium is an isomer of the sulfur-containing nucleotide dUTPαS.Color and Shape:Odour Solid
![6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT75185.webp&w=3840&q=75)
