Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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SRT 1720 dihydrochloride
CAS:SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).Formula:C25H25Cl2N7OSPurity:98.58%Color and Shape:SolidMolecular weight:542.48Tucidinostat
CAS:Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formula:C22H19FN4O2Purity:97.01% - 99.95%Color and Shape:SolidMolecular weight:390.41Ref: TM-T4481
5mg60.00€10mg95.00€25mg159.00€50mg250.00€100mg399.00€200mg558.00€500mg832.00€1mL*10mM (DMSO)60.00€TH34
CAS:TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formula:C15H16N2O2Purity:98.32%Color and Shape:SolidMolecular weight:256.3AZD5305
CAS:AZD5305 is a potent, selective and oral active PARP inhibitor.Formula:C22H26N6O2Purity:98.68% - 99.93%Color and Shape:SolidMolecular weight:406.48Ref: TM-T9165
1mg107.00€5mg222.00€10mg358.00€25mg597.00€50mg850.00€100mg1,153.00€1mL*10mM (DMSO)245.00€Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurity:97.05% - 98.62%Color and Shape:SolidMolecular weight:225.29Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurity:99.01% - 99.92%Color and Shape:SolidMolecular weight:399.9Ref: TM-T6026
2mg34.00€5mg55.00€10mg89.00€25mg170.00€50mg269.00€100mg424.00€200mg593.00€1mL*10mM (DMSO)58.00€MPT0G211 mesylate
CAS:MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formula:C18H19N3O5SColor and Shape:SolidMolecular weight:389.43MM-102 TFA
CAS:MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formula:C37H50F5N7O6Purity:99.4% - 99.78%Color and Shape:SolidMolecular weight:783.83Ref: TM-T8768
1mg37.00€2mg49.00€5mg100.00€10mg165.00€25mg269.00€50mg399.00€100mg587.00€1mL*10mM (DMSO)141.00€UNC 669
CAS:UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formula:C15H20BrN3OPurity:97.38%Color and Shape:SolidMolecular weight:338.24G007-LK
CAS:G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96Ref: TM-T6842
1mg50.00€2mg66.00€5mg94.00€10mg158.00€25mg315.00€50mg502.00€100mg707.00€1mL*10mM (DMSO)116.00€γ-Oryzanol
CAS:γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFormula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9DR2313
CAS:DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24JQKD82
CAS:JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formula:C27H40N4O5Purity:100.00%Color and Shape:SolidMolecular weight:500.63Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58CPI203
CAS:CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurity:99.13% - 99.77%Color and Shape:SolidMolecular weight:399.9PHD-1-IN-1
CAS:PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formula:C13H8N4Purity:99.74%Color and Shape:SolidMolecular weight:220.23Ref: TM-T9627
1mg42.00€5mg92.00€10mg132.00€25mg231.00€50mg349.00€100mg522.00€200mg710.00€1mL*10mM (DMSO)90.00€RO8191
CAS:RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formula:C14H5F6N5OPurity:98% - 98.85%Color and Shape:SolidMolecular weight:373.21Ref: TM-T22142
1mg43.00€2mg55.00€5mg93.00€10mg137.00€25mg254.00€50mg380.00€100mg573.00€500mg1,189.00€ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59UPF 1069
CAS:UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29Pinometostat
CAS:Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Formula:C30H42N8O3Purity:99.19% - 99.86%Color and Shape:SolidMolecular weight:562.71Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34AZ6102
CAS:AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formula:C25H28N6OPurity:97.98% - 99.91%Color and Shape:SolidMolecular weight:428.53Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9Ref: TM-T1906
1mg40.00€2mg54.00€5mg88.00€10mg118.00€25mg205.00€50mg339.00€100mg507.00€200mg712.00€500mg1,108.00€1mL*10mM (DMSO)87.00€(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurity:99.49% - 99.65%Color and Shape:SolidMolecular weight:237.26Ref: TM-T2040
1mg34.00€2mg47.00€5mg66.00€10mg92.00€25mg164.00€50mg299.00€100mg540.00€1mL*10mM (DMSO)66.00€COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formula:C13H8Cl4N2OPurity:98.96%Color and Shape:SolidMolecular weight:350.03WZ4003
CAS:WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formula:C25H29ClN6O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:496.99Ref: TM-T6291
5mg48.00€10mg73.00€25mg111.00€50mg166.00€100mg241.00€200mg358.00€500mg590.00€1mL*10mM (DMSO)50.00€GSK-LSD1 dihydrochloride
CAS:GSK-LSD1 dihydrochloride: potent LSD1 inhibitor, >1000x selective over MAO-A/B, LSD2, IC50: 16 nM.Formula:C14H22Cl2N2Purity:98.72% - >99.99%Color and Shape:SolidMolecular weight:289.24Ref: TM-T2315
1mg38.00€2mg50.00€5mg67.00€10mg98.00€25mg198.00€50mg301.00€100mg495.00€500mg1,054.00€1mL*10mM (DMSO)67.00€Fraxinellone
CAS:1.Formula:C14H16O3Purity:99.35% - 99.92%Color and Shape:SolidMolecular weight:232.27Ref: TM-T6S0071
2mg34.00€5mg50.00€10mg84.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)81.00€HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32Ref: TM-T50099
5mg37.00€10mg60.00€25mg111.00€50mg200.00€100mg299.00€200mg430.00€1mL*10mM (DMSO)44.00€I-BRD9
CAS:I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formula:C22H22F3N3O3S2Purity:98.16% - 99.51%Color and Shape:SolidMolecular weight:497.55Ref: TM-T6859
1mg38.00€2mg49.00€5mg71.00€10mg107.00€25mg205.00€50mg389.00€100mg577.00€1mL*10mM (DMSO)79.00€ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Ref: TM-T4697
1mg44.00€2mg56.00€5mg90.00€10mg142.00€25mg284.00€50mg409.00€100mg500.00€200mg718.00€1mL*10mM (DMSO)90.00€Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purity:99.79% - 99.82%Color and Shape:SolidMolecular weight:298.34MRTX-1719
CAS:MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.Formula:C23H18ClFN6O2Purity:98.27% - 99.18%Color and Shape:SolidMolecular weight:464.88Pim1/AKK1-IN-1
CAS:Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.Formula:C20H13N5OPurity:97.03% - 98.69%Color and Shape:SolidMolecular weight:339.35Ref: TM-T5093
1mg85.00€2mg124.00€5mg173.00€10mg263.00€25mg464.00€50mg672.00€100mg945.00€1mL*10mM (DMSO)192.00€dBET6
CAS:dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.Formula:C42H45ClN8O7SPurity:97.57% - 99.12%Color and Shape:SolidMolecular weight:841.37Ref: TM-T5130
1mg50.00€5mg92.00€10mg160.00€25mg290.00€50mg467.00€100mg675.00€200mg850.00€500mg1,243.00€1mL*10mM (DMSO)148.00€SGC-SMARCA-BRDVIII
CAS:SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formula:C19H25N5O3Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:371.43Ref: TM-T9568
1mg44.00€5mg66.00€10mg101.00€25mg222.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)54.00€5-AIQ
CAS:5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.Formula:C9H8N2OPurity:95.95%Color and Shape:SolidMolecular weight:160.17BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purity:99.53% - 99.82%Color and Shape:SolidMolecular weight:413.47Hispidulin
CAS:Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formula:C16H12O6Purity:98.53% - 99.87%Color and Shape:SolidMolecular weight:300.26KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purity:98% - 99.11%Color and Shape:SolidMolecular weight:570.38RK-287107
CAS:RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formula:C22H26F2N4O2Purity:99.64%Color and Shape:SolidMolecular weight:416.46MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurity:99.18% - >99.99%Color and Shape:SolidMolecular weight:484.54Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formula:C19H36O5Purity:99.85% - 99.94%Color and Shape:SolidMolecular weight:344.49Ref: TM-T3625
2mg34.00€5mg50.00€10mg70.00€25mg118.00€50mg207.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)52.00€Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purity:97.11% - 99.02%Color and Shape:SolidMolecular weight:525.08Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.30EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formula:C17H15N5O3SPurity:98.14% - 99.33%Color and Shape:SolidMolecular weight:369.4Iniparib
CAS:Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formula:C7H5IN2O3Purity:98.93%Color and Shape:SolidMolecular weight:292.03Ref: TM-T6224
5mg52.00€10mg73.00€25mg119.00€50mg216.00€100mg340.00€200mg540.00€500mg863.00€1mL*10mM (DMSO)52.00€GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43Ref: TM-T3076
1mg38.00€2mg50.00€5mg84.00€10mg137.00€25mg250.00€50mg442.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)93.00€NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Ref: TM-T3261
1mg43.00€2mg54.00€5mg84.00€10mg122.00€25mg248.00€50mg421.00€100mg617.00€1mL*10mM (DMSO)93.00€RBN012759
CAS:RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.46Ref: TM-T22414
1mg104.00€2mgTo inquire5mg250.00€10mg373.00€25mg645.00€50mg938.00€100mg1,311.00€200mg1,768.00€1mL*10mM (DMSO)274.00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg50.00€2mg67.00€5mg84.00€10mg120.00€25mg220.00€50mg356.00€100mg537.00€1mL*10mM (DMSO)88.00€1,2-Dipalmitoyl-sn-glycerol
CAS:1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91Ruboxistaurin mesylate
CAS:Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formula:C29H32N4O6SPurity:98%Color and Shape:SolidMolecular weight:564.65AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formula:C29H38Cl2N4O4Purity:98.18%Color and Shape:SolidMolecular weight:577.54Ref: TM-TQ0100
1mg60.00€5mg130.00€10mg178.00€25mg295.00€50mg462.00€100mg623.00€1mL*10mM (DMSO)165.00€MR837
CAS:MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36Ref: TM-T8879
2mg38.00€5mg55.00€10mg92.00€25mg138.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)66.00€MK-8617
CAS:MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.44Ref: TM-T6255
1mg44.00€2mg57.00€5mg93.00€10mg133.00€25mg260.00€50mg416.00€100mg665.00€200mg888.00€1mL*10mM (DMSO)92.00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Ref: TM-T8685
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)177.00€8-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formula:C8H5ClN2OPurity:98.79%Color and Shape:SolidMolecular weight:180.59(R)-(-)-JQ1 Enantiomer
CAS:(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99ICG001
CAS:ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formula:C33H32N4O4Purity:99.06% - 99.95%Color and Shape:SolidMolecular weight:548.63Ref: TM-T2237
1mg34.00€5mg66.00€10mg101.00€25mg197.00€50mg341.00€100mg530.00€500mg1,134.00€1mL*10mM (DMSO)81.00€Rucaparib hydrochloride
CAS:Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formula:C19H19ClFN3OColor and Shape:SolidMolecular weight:359.83GSK1379725A
CAS:GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
Formula:C23H23FN6O3Purity:99.51%Color and Shape:SolidMolecular weight:450.47DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14Bobcat339
CAS:Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formula:C16H12ClN3OPurity:97.79% - 98.76%Color and Shape:SolidMolecular weight:297.74Rucaparib acetate
CAS:Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formula:C21H22FN3O3Color and Shape:SolidMolecular weight:383.423JQEZ5
CAS:JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formula:C30H38N8O2Purity:98.14% - ≥98%Color and Shape:SolidMolecular weight:542.68Protein kinase inhibitor 6
CAS:Protein kinase inhibitor 6 is a protein kinase inhibitor.Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29Ref: TM-T9779
2mg34.00€5mg52.00€10mg86.00€25mg163.00€50mg222.00€100mg324.00€200mg440.00€1mL*10mM (DMSO)52.00€MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formula:C103H156N28O24S2Purity:100%Color and Shape:SolidMolecular weight:2234.64EB-47 dihydrochloride
CAS:EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formula:C24H29Cl2N9O6Color and Shape:SolidMolecular weight:610.45PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purity:98.48%Color and Shape:SolidMolecular weight:366.3Ref: TM-T16538
1mg57.00€5mg120.00€10mg222.00€25mg326.00€50mg485.00€100mg612.00€200mg850.00€500mg1,243.00€1mL*10mM (DMSO)133.00€Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurity:99.78% - 99.99%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Ref: TM-T8381
1mg49.00€2mg66.00€5mg90.00€10mg170.00€25mg281.00€50mg394.00€100mg550.00€1mL*10mM (DMSO)105.00€XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Ruboxistaurin
CAS:Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formula:C28H28N4O3Color and Shape:SolidMolecular weight:468.55YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formula:C30H37N7O2Purity:99.52% - 99.79%Color and Shape:SolidMolecular weight:527.66MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formula:C20H30Cl3N3O2Color and Shape:SolidMolecular weight:450.83SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.85-Ph-IAA
CAS:5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
Formula:C16H13NO2Purity:99.37% - 99.973%Color and Shape:SolidMolecular weight:251.28Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17Birabresib
CAS:Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formula:C25H22ClN5O2SPurity:98.3% - 99.36%Color and Shape:SolidMolecular weight:491.99Ref: TM-T6032
2mg46.00€5mg70.00€10mg90.00€25mg142.00€50mg222.00€100mg375.00€200mg560.00€500mg893.00€1mL*10mM (DMSO)74.00€(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurity:97.57% - 99.97%Color and Shape:SolidMolecular weight:456.99Ref: TM-T2110
1mg34.00€2mg42.00€5mg57.00€10mg74.00€25mg90.00€50mg137.00€100mg178.00€200mg268.00€500mg485.00€1mL*10mM (DMSO)63.00€AZD-2461
CAS:AZD2461 is a novel PARP inhibitor.Formula:C22H22FN3O3Purity:98% - 99.87%Color and Shape:SolidMolecular weight:395.43Menin-MLL inhibitor 20
CAS:Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formula:C33H40N8O4Purity:97.77%Color and Shape:SolidMolecular weight:612.72Ref: TM-T9399
1mg38.00€5mg86.00€10mg128.00€25mg250.00€50mg369.00€100mg527.00€200mg712.00€1mL*10mM (DMSO)95.00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41Isoxazole
CAS:Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formula:C3H3NOPurity:98% - 99.34%Color and Shape:Colorless LiquidMolecular weight:69.06Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14UMB298
CAS:UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formula:C27H31ClN4O2Purity:99.76%Color and Shape:SolidMolecular weight:479.01Ref: TM-T9194
1mg46.00€5mg94.00€10mg149.00€25mg250.00€50mg351.00€100mg480.00€200mg622.00€1mL*10mM (DMSO)99.00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS:3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formula:C9H10N2OPurity:99.3% - 99.64%Color and Shape:SolidMolecular weight:162.19Ref: TM-T50006
2mg37.00€5mg52.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€500mg642.00€1mL*10mM (DMSO)56.00€Alobresib
CAS:Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formula:C26H23N5O2Purity:97.63%Color and Shape:SolidMolecular weight:437.49Ref: TM-T8495
1mg70.00€2mg87.00€5mg137.00€10mg260.00€25mg507.00€50mg713.00€100mg982.00€1mL*10mM (DMSO)150.00€PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg107.00€2mg152.00€5mg219.00€10mg349.00€25mg583.00€50mg833.00€100mg1,134.00€500mg2,268.00€1mL*10mM (DMSO)226.00€Tubacin
CAS:Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formula:C41H43N3O7SPurity:97.62% - 98.75%Color and Shape:SolidMolecular weight:721.86MT-DADMe-ImmA
CAS:MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).Formula:C13H19N5OSPurity:99.56%Color and Shape:SolidMolecular weight:293.39Ref: TM-TQ0008
1mg70.00€5mg135.00€10mg225.00€25mg399.00€50mg560.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)169.00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurity:98% - 99.45%Color and Shape:SolidMolecular weight:393.49Ref: TM-T1825
1mg35.00€2mg50.00€5mg66.00€10mg84.00€25mg156.00€50mg212.00€100mg371.00€1mL*10mM (DMSO)66.00€J-147
CAS:J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formula:C18H17F3N2O2Purity:99.61% - >99.99%Color and Shape:SolidMolecular weight:350.33N-Oxalylglycine
CAS:N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.Formula:C4H5NO5Purity:99.23%Color and Shape:Colourless SolidMolecular weight:147.09
