Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2613 products of "Chromatin/Epigenetics"
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Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg44.00€5mg86.00€10mg135.00€25mg254.00€50mg423.00€100mg605.00€200mg845.00€1mL*10mM (DMSO)94.00€AK-7
CAS:AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.Formula:C19H21BrN2O3SPurity:98.43% - 99.34%Color and Shape:SolidMolecular weight:437.35Ref: TM-T5490
1mg34.00€2mg47.00€5mg71.00€10mg100.00€25mg177.00€50mg313.00€100mg512.00€1mL*10mM (DMSO)89.00€PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formula:C78H132N30O18Purity:98.78%Color and Shape:SolidMolecular weight:1778.10Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurity:99.6%Color and Shape:SolidMolecular weight:122.12MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurity:98.91%Color and Shape:SolidMolecular weight:248.36Ref: TM-T4378
2mg34.00€5mg49.00€10mg80.00€25mg149.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23PTACH
CAS:PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).Formula:C20H26N2O2S2Purity:87.44% - 99.74%Color and Shape:SolidMolecular weight:390.56MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurity:98.31% - 99.87%Color and Shape:SolidMolecular weight:287.4Ref: TM-T6900
1mg37.00€2mg49.00€5mg84.00€10mg113.00€25mg230.00€50mg358.00€100mg532.00€500mg1,153.00€1mL*10mM (DMSO)79.00€E1231
CAS:E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formula:C21H21N3O3Purity:98.45%Color and Shape:SolidMolecular weight:363.41Ref: TM-T9106
1mg34.00€5mg70.00€10mg99.00€25mg195.00€50mg311.00€100mg449.00€500mg888.00€1mL*10mM (DMSO)94.00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Ref: TM-T26019
1mg39.00€2mg52.00€5mg87.00€10mg138.00€25mg281.00€50mg425.00€100mg625.00€200mg883.00€1mL*10mM (DMSO)95.00€EDO-S101
CAS:EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.Formula:C19H28Cl2N4O2Purity:98.02% - 99.44%Color and Shape:SolidMolecular weight:415.36ACY-738
CAS:ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.Formula:C14H14N4O2Purity:98.85% - 99.89%Color and Shape:SolidMolecular weight:270.29Ref: TM-T3509
1mg46.00€2mg62.00€5mg90.00€10mg165.00€25mg268.00€50mg439.00€100mg582.00€1mL*10mM (DMSO)100.00€CAY10602
CAS:CAY10602 activates SIRT1, suppresses NF-κB/TNF-α in THP-1 cells with 75% efficacy at 60 μM, non-toxic.Formula:C22H15FN4O2SPurity:98.92%Color and Shape:SolidMolecular weight:418.44SKLB-23bb
CAS:SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.Formula:C21H24N4O4Purity:97.58%Color and Shape:SolidMolecular weight:396.44Ref: TM-T5830
1mg50.00€5mg133.00€10mg187.00€25mg304.00€50mg424.00€100mg587.00€200mg800.00€1mL*10mM (DMSO)147.00€GSK121
CAS:GSK121 is an inhibitor of selective PAD4.
Formula:C25H26F3N5O3Purity:98.92%Color and Shape:SolidMolecular weight:501.51PJ34
CAS:PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formula:C17H17N3O2Purity:95.05% - 99.85%Color and Shape:SolidMolecular weight:295.34TH34
CAS:TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formula:C15H16N2O2Purity:98.32%Color and Shape:SolidMolecular weight:256.3HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32Ref: TM-T50099
5mg37.00€10mg60.00€25mg111.00€50mg200.00€100mg299.00€200mg430.00€1mL*10mM (DMSO)44.00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Ref: TM-T8685
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)177.00€SirReal2
CAS:SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formula:C22H20N4OS2Purity:99.52% - 99.75%Color and Shape:SolidMolecular weight:420.55Ref: TM-T6984
1mg37.00€2mg52.00€5mg74.00€10mg102.00€25mg187.00€50mg295.00€100mg477.00€1mL*10mM (DMSO)86.00€Selisistat R-enantiomer
CAS:Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).Formula:C13H13ClN2OPurity:99.8%Color and Shape:SolidMolecular weight:248.71Ref: TM-T15263
1mg101.00€2mg150.00€5mg245.00€10mg356.00€25mg597.00€50mg835.00€100mg1,108.00€1mL*10mM (DMSO)269.00€Selisistat S-enantiomer
CAS:Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.Formula:C13H13ClN2OPurity:99.86%Color and Shape:SolidMolecular weight:248.71Ref: TM-T7058
1mg142.00€2mg203.00€5mg314.00€10mg447.00€25mg713.00€50mg1,018.00€1mL*10mM (DMSO)359.00€TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formula:C27H30F3N3O3Purity:97.71% - 98.00%Color and Shape:SolidMolecular weight:501.54Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purity:99.79% - 99.82%Color and Shape:SolidMolecular weight:298.34Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formula:C65H122N18O16SPurity:99.62%Color and Shape:SolidMolecular weight:1443.96dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurity:98.02% - 99.3%Color and Shape:SolidMolecular weight:785.27Ref: TM-T4495
1mg50.00€5mg99.00€10mg161.00€25mg268.00€50mg427.00€100mg650.00€200mg888.00€1mL*10mM (DMSO)145.00€HDAC-IN-3
CAS:HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.Formula:C22H33N3O4Purity:98.61%Color and Shape:SolidMolecular weight:403.52ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05%Color and Shape:SolidMolecular weight:367.91Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.64MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purity:98% - 99.81%Color and Shape:SolidMolecular weight:297.31SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purity:99.61% - 99.71%Color and Shape:SolidMolecular weight:312.41Ref: TM-T7089
1mg84.00€2mg113.00€5mg215.00€10mg324.00€25mg533.00€50mg777.00€100mg1,071.00€1mL*10mM (DMSO)152.00€CPI-1205
CAS:CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。Formula:C27H33F3N4O3Purity:98.71% - 99.7%Color and Shape:SolidMolecular weight:518.57DCLX069
CAS:DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.Formula:C20H25N3O2Purity:97.76%Color and Shape:SolidMolecular weight:339.43Ref: TM-T27133
1mg38.00€2mg49.00€5mg79.00€10mg111.00€25mg187.00€50mg305.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)92.00€AZD5305
CAS:AZD5305 is a potent, selective and oral active PARP inhibitor.Formula:C22H26N6O2Purity:98.68% - 99.93%Color and Shape:SolidMolecular weight:406.48Ref: TM-T9165
1mg107.00€5mg222.00€10mg358.00€25mg597.00€50mg850.00€100mg1,153.00€1mL*10mM (DMSO)245.00€Peficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purity:98.67% - 99.4%Color and Shape:SolidMolecular weight:326.39Ref: TM-T6933
2mg38.00€5mg63.00€10mg99.00€25mg172.00€50mg268.00€100mg416.00€200mg610.00€1mL*10mM (DMSO)70.00€E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purity:98.92% - 99.91%Color and Shape:SolidMolecular weight:725.85Ref: TM-T11136
1mg93.00€2mg128.00€5mg219.00€10mg356.00€25mg613.00€50mg873.00€100mg1,161.00€1mL*10mM (DMSO)350.00€Olaparib
CAS:View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formula:C24H23FN4O3Purity:98% - >99.99%Color and Shape:SolidMolecular weight:434.46TP-3654
CAS:TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formula:C22H25F3N4OPurity:99.8% - 99.95%Color and Shape:SolidMolecular weight:418.46E7449
CAS:E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formula:C18H15N5OPurity:97.13%Color and Shape:SolidMolecular weight:317.34Ref: TM-T4471
1mg34.00€5mg88.00€10mg114.00€25mg178.00€50mg269.00€100mg399.00€200mg590.00€1mL*10mM (DMSO)88.00€Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formula:C15H12O5Purity:99.42% - 99.82%Color and Shape:SolidMolecular weight:272.25Ref: TM-TJS1779
1mg88.00€5mg195.00€10mg318.00€25mg523.00€50mg743.00€100mg999.00€1mL*10mM (DMSO)178.00€Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9Ref: TM-T1906
1mg40.00€2mg54.00€5mg88.00€10mg118.00€25mg205.00€50mg339.00€100mg507.00€200mg712.00€500mg1,108.00€1mL*10mM (DMSO)87.00€(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95WM-1119
CAS:WM-1119 is a highly potent, selective KAT6A/B inhibitorFormula:C18H13F2N3O3SPurity:96.59% - 99.58%Color and Shape:SolidMolecular weight:389.38XD14
CAS:XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.
Formula:C20H27N3O5SPurity:97.46%Color and Shape:SolidMolecular weight:421.51FL-411
CAS:FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.Formula:C18H19N3O2SPurity:98.19%Color and Shape:SolidMolecular weight:341.43GSK3685032
CAS:GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Formula:C22H24N6OSPurity:98.56% - 99.49%Color and Shape:SolidMolecular weight:420.53Daminozide
CAS:Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.Formula:C6H12N2O3Purity:99.86%Color and Shape:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Molecular weight:160.17GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purity:98.35% - 98.65%Color and Shape:SolidMolecular weight:394.47Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purity:98.52% - >99.99%Color and Shape:SolidMolecular weight:425.46Ref: TM-T14687
1mg56.00€5mg137.00€10mg248.00€25mg389.00€50mg575.00€100mg817.00€1mL*10mM (DMSO)149.00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purity:97.07% - 99.56%Color and Shape:SolidMolecular weight:414.46Ref: TM-T1849
1mg35.00€2mg50.00€5mg77.00€10mg89.00€25mg158.00€50mg245.00€100mg385.00€200mg592.00€1mL*10mM (DMSO)84.00€MS436
CAS:MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42Ref: TM-T1854
2mg42.00€5mg62.00€10mg95.00€25mg172.00€50mg268.00€100mg429.00€200mg615.00€1mL*10mM (DMSO)69.00€SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formula:C18H15ClN6OS2·CH4O3SPurity:99.44% - 99.92%Color and Shape:SolidMolecular weight:527.04BAY-598
CAS:BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.Formula:C22H20Cl2F2N6O3Purity:99.18% - 99.78%Color and Shape:SolidMolecular weight:525.342',3',5'-triacetyl-5-Azacytidine
CAS:2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formula:C14H18N4O8Purity:98.34%Color and Shape:SolidMolecular weight:370.31Ref: TM-T7840
2mg38.00€5mg50.00€10mg75.00€25mg122.00€50mg177.00€100mg266.00€200mg385.00€1mL*10mM (DMSO)60.00€GSK046
CAS:GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.Formula:C23H27FN2O4Purity:99.97%Color and Shape:SolidMolecular weight:414.47Ref: TM-T8932
1mg57.00€5mg120.00€10mg200.00€25mg447.00€50mg715.00€100mg1,108.00€200mg1,485.00€1mL*10mM (DMSO)133.00€RO495
CAS:RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormula:C17H14Cl2N6OPurity:97.94%Color and Shape:SolidMolecular weight:389.24Ref: TM-T22416
1mg46.00€5mg86.00€10mg126.00€25mg235.00€50mg344.00€100mg465.00€200mg625.00€1mL*10mM (DMSO)94.00€GSK6853
CAS:GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.Formula:C22H27N5O3Purity:98.71% - 99.21%Color and Shape:SolidMolecular weight:409.48(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360Niraparib
CAS:Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formula:C19H20N4OPurity:98% - 99.91%Color and Shape:SolidMolecular weight:320.39Ref: TM-T3231
5mg57.00€10mg84.00€25mg105.00€50mg137.00€100mg205.00€200mg304.00€500mg515.00€1mL*10mM (DMSO)63.00€AKBA
CAS:AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.Formula:C32H48O5Purity:97.85% - 99.77%Color and Shape:SolidMolecular weight:512.72MN-64
CAS:MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.Formula:C18H16O2Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:264.32SGC0946
CAS:SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Formula:C28H40BrN7O4Purity:98% - 99.82%Color and Shape:SolidMolecular weight:618.57SMI-16a
CAS:SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (Formula:C13H13NO3SPurity:99.99%Color and Shape:SolidMolecular weight:263.31Ref: TM-T3989
1mg34.00€2mg46.00€5mg66.00€10mg93.00€25mg152.00€50mg222.00€100mg334.00€1mL*10mM (DMSO)87.00€OF-1
CAS:OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.Formula:C17H18BrN3O4SPurity:98.55% - ≥95%Color and Shape:SolidMolecular weight:440.31Ref: TM-T2127
1mg35.00€5mg74.00€10mg123.00€25mg240.00€50mg385.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)74.00€AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formula:C28H31N5O2Purity:98.26% - 99.96%Color and Shape:SolidMolecular weight:469.58JMJD7-IN-1
CAS:JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.Formula:C16H8Cl2N2O4Purity:99.66%Color and Shape:SolidMolecular weight:363.15PF-9366
CAS:PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).Formula:C20H19ClN4Purity:97.28% - 99.88%Color and Shape:SolidMolecular weight:350.84Ref: TM-T5191
1mg46.00€5mg96.00€10mg130.00€25mg227.00€50mg321.00€100mg442.00€200mg642.00€1mL*10mM (DMSO)92.00€AG-270
CAS:AG-270 is an allosteric and orally active inhibitor of MAT2A.Formula:C30H27N5O2Purity:98.28% - 98.87%Color and Shape:SolidMolecular weight:489.57Ref: TM-T9050
1mg110.00€2mgTo inquire5mg256.00€10mg378.00€25mg628.00€50mg882.00€100mg1,225.00€200mg1,673.00€C-82
CAS:C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.Formula:C33H34N6O4Purity:98.86% - 99.66%Color and Shape:SolidMolecular weight:578.66Itacitinib
CAS:Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.Formula:C26H23F4N9OPurity:96.4% - 99.5%Color and Shape:SolidMolecular weight:553.51A-966492
CAS:A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.Formula:C18H17FN4OPurity:98.53% - 99.27%Color and Shape:SolidMolecular weight:324.35Ref: TM-T6366
2mg34.00€5mg52.00€10mg94.00€25mg163.00€50mg261.00€100mg374.00€200mg530.00€1mL*10mM (DMSO)52.00€GSK503
CAS:GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.Formula:C31H38N6O2Purity:98% - 99.89%Color and Shape:SolidMolecular weight:526.67PFI-4
CAS:PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.Formula:C21H24N4O3Purity:99.53% - ≥95%Color and Shape:SolidMolecular weight:380.44NI-57
CAS:NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).Formula:C19H17N3O4SPurity:99.88% - >99.99%Color and Shape:SolidMolecular weight:383.42Menin-MLL inhibitor MI-2
CAS:Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55Ref: TM-T2649
2mg39.00€5mg58.00€10mg84.00€25mg160.00€50mg230.00€100mg356.00€200mg522.00€1mL*10mM (DMSO)64.00€Molibresib besylate
CAS:Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.Formula:C28H28ClN5O5SPurity:99.64% - 99.64%Color and Shape:SolidMolecular weight:582.07Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26Ref: TM-T6S1315
1mg37.00€5mg71.00€10mg90.00€25mg147.00€50mg208.00€100mg309.00€200mg447.00€1mL*10mM (DMSO)84.00€Tofacitinib
CAS:Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formula:C16H20N6OPurity:99% - >99.99%Color and Shape:SolidMolecular weight:312.37BRD9539
CAS:BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFormula:C24H21N3O3Purity:98% - 99.57%Color and Shape:SolidMolecular weight:399.44Seclidemstat
CAS:Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.Formula:C20H23ClN4O4SPurity:98.28% - 99.76%Color and Shape:SolidMolecular weight:450.94Ref: TM-T4527
5mg46.00€10mg69.00€25mg114.00€50mg177.00€100mg335.00€200mg500.00€500mg807.00€1mL*10mM (DMSO)50.00€Veliparib dihydrochloride
CAS:Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formula:C13H18Cl2N4OPurity:98% - 99.81%Color and Shape:SolidMolecular weight:317.21Remodelin
CAS:Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.Formula:C15H14N4SPurity:99.39% - 99.83%Color and Shape:SolidMolecular weight:282.363Ref: TM-T3499
2mg37.00€5mg52.00€10mg73.00€25mg123.00€50mg175.00€100mg236.00€200mg353.00€1mL*10mM (DMSO)56.00€PT-2385
CAS:PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).Formula:C17H12F3NO4SPurity:98.91% - 99.55%Color and Shape:SolidMolecular weight:383.34Ref: TM-T7848
1mg63.00€2mg93.00€5mg144.00€10mg222.00€25mg379.00€50mg532.00€100mg740.00€200mg982.00€1mL*10mM (DMSO)119.00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formula:C23H23FN4O2Purity:99.86%Color and Shape:SolidMolecular weight:406.45Ref: TM-T9430
1mg46.00€2mg59.00€5mg90.00€10mg137.00€25mg268.00€50mg439.00€100mg645.00€1mL*10mM (DMSO)90.00€RN-1 dihydrochloride
CAS:RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).Formula:C23H31Cl2N3O2Purity:99.64%Color and Shape:SolidMolecular weight:452.42Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36Ref: TM-T1829
5mg55.00€10mg71.00€25mg96.00€50mg110.00€100mg146.00€200mg231.00€500mg393.00€1mL*10mM (DMSO)62.00€GSK2801
CAS:GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Formula:C20H21NO4SPurity:97.78% - 99.45%Color and Shape:SolidMolecular weight:371.455-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Formula:C10H15N3O4Purity:99.18% - 99.69%Color and Shape:SolidMolecular weight:241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.Formula:C10H11NOSPurity:99.68%Color and Shape:SolidMolecular weight:193.275-Fluoro-2'-deoxycytidine
CAS:5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .Formula:C9H12FN3O4Purity:97.91%Color and Shape:Fine White PowderMolecular weight:245.21Ref: TM-T7718
2mg34.00€5mg48.00€10mg64.00€25mg90.00€50mg138.00€100mg200.00€200mg296.00€500mg497.00€1mL*10mM (DMSO)50.00€A-366
CAS:A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.Formula:C19H27N3O2Purity:97.28% - 99.8%Color and Shape:SolidMolecular weight:329.44Ref: TM-T3624
1mg35.00€2mg50.00€5mg74.00€10mg90.00€25mg208.00€50mg359.00€100mg530.00€1mL*10mM (DMSO)82.00€UNC3866 TFA(1872382-47-2 free base)
CAS:UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C45H67F3N6O10Purity:98.43%Color and Shape:SolidMolecular weight:909.046-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19IOX4
CAS:IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Formula:C15H16N6O3Purity:99.97%Color and Shape:SolidMolecular weight:328.33NEO2734
CAS:NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Formula:C22H24F3N3O3Purity:98.72% - 98.8%Color and Shape:SolidMolecular weight:435.44Ref: TM-T8658
1mg108.00€5mg260.00€10mg430.00€25mg710.00€50mg973.00€100mg1,333.00€500mg2,673.00€1mL*10mM (DMSO)286.00€Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:460.73XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg52.00€2mg73.00€5mg94.00€10mg141.00€25mg244.00€50mg371.00€100mg552.00€1mL*10mM (DMSO)104.00€Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59
