DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(422 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
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Found 959 products of "DNA Damage/DNA Repair"
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1-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Formula:C14H8O3Purity:99.56%Color and Shape:Orange Red Needles Red-Orange To Fine Yellow CrystalsMolecular weight:224.21Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formula:C20H15N3O6Purity:97.54%Color and Shape:Yellow Amorphous PowderMolecular weight:393.35AG14361
CAS:<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Formula:C19H20N4OPurity:98.7% - 99.93%Color and Shape:SolidMolecular weight:320.39Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formula:C19H23ClFN3O4Purity:99.85% - 99.89%Color and Shape:SolidMolecular weight:411.86EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C9H13N3O6Purity:99.14% - 99.73%Color and Shape:SolidMolecular weight:259.22CXD101
CAS:<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Formula:C24H29N5OPurity:99.82%Color and Shape:SolidMolecular weight:403.521-Oleoyl lysophosphatidic acid sodium
CAS:<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Formula:C21H40O7P·NaPurity:98.75% - 99.24%Color and Shape:SolidMolecular weight:458.51MK-4827 Racemate
CAS:<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Formula:C19H20N4OPurity:99.86%Color and Shape:SolidMolecular weight:320.39Cycloastragenol
CAS:<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Formula:C30H50O5Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:490.71GNE-3511
CAS:GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.Formula:C23H26F2N6OPurity:98.3% - 99.51%Color and Shape:SolidMolecular weight:440.49PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Formula:C14H16ClN3O4S2Purity:97.72%Color and Shape:SolidMolecular weight:389.889-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formula:C20H16N2O5Purity:98.28%Color and Shape:SolidMolecular weight:364.35Xanthosine 5'-monophosphate sodium salt
CAS:<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formula:C10H11N4Na2O9PPurity:99% - 99.77%Color and Shape:SolidMolecular weight:408.17Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formula:C9H16N3O13P3Purity:99.68%Color and Shape:SolidMolecular weight:467.16NKL 22
CAS:<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Formula:C19H23N3O2Purity:96.16% - 96.24%Color and Shape:SolidMolecular weight:325.4AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Formula:C23H13Cl2N3O2Purity:98.31%Color and Shape:SolidMolecular weight:434.27MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formula:C18H16O2Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:264.32E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formula:C18H15N5OPurity:97.13%Color and Shape:SolidMolecular weight:317.34Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formula:C20H20N8Na2O5Purity:99.77% - 99.96%Color and Shape:SolidMolecular weight:498.4AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formula:C18H20N8O2Purity:99.03% - 99.85%Color and Shape:SolidMolecular weight:380.4AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formula:C25H28N6OPurity:97.98% - 99.91%Color and Shape:SolidMolecular weight:428.53OUL35
CAS:<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Formula:C14H12N2O3Purity:99.2%Color and Shape:SolidMolecular weight:256.26AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Formula:C12H15ClO3Purity:98.77%Color and Shape:Oil LiquidMolecular weight:242.70Selisistat S-enantiomer
CAS:<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Formula:C13H13ClN2OPurity:99.86%Color and Shape:SolidMolecular weight:248.71Suramin Sodium Salt
CAS:<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Formula:C51H34N6Na6O23S6Purity:97.47% - 99.97%Color and Shape:WhiteMolecular weight:1429.15Citarinostat
CAS:<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Formula:C24H26ClN5O3Purity:98.06% - 99.06%Color and Shape:SolidMolecular weight:467.95Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formula:C16H15FN4OPurity:99.69%Color and Shape:SolidMolecular weight:298.31Fluzoparib
CAS:<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formula:C22H16F4N6O2Purity:98.53% - 99.63%Color and Shape:SolidMolecular weight:472.4Bisantrene
CAS:<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Formula:C22H22N8Purity:96.07% - 98.57%Color and Shape:SolidMolecular weight:398.46DMNB
CAS:<p>DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway of DSB repair in human cells.</p>Formula:C9H9NO5Purity:97.87%Color and Shape:Yellow SolidMolecular weight:211.17Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formula:C16H12ClN3OPurity:97.79% - 99.24%Color and Shape:SolidMolecular weight:297.74CGK733
CAS:<p>CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.</p>Formula:C23H18Cl3FN4O3SPurity:98% - 99.67%Color and Shape:SolidMolecular weight:555.84AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formula:C22H24N4O4Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:408.452-Aminopurine
CAS:<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Formula:C5H5N5Purity:99.51%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:135.13Compound 401
CAS:<p>Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.</p>Formula:C16H15N3O2Purity:99.73% - 99.78%Color and Shape:SolidMolecular weight:281.31Selisistat R-enantiomer
CAS:<p>Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).</p>Formula:C13H13ClN2OPurity:99.8%Color and Shape:SolidMolecular weight:248.71G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Formula:C39H43N3O11SPurity:≥98%Color and Shape:SolidMolecular weight:761.84Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:97.7% - 98.41%Color and Shape:SolidMolecular weight:510.61Isosteviol
CAS:<p>Isosteviol is a natural sweetener with anti-inflammatory, anti-tumor, glucose-lowering, and other health benefits.</p>Formula:C20H30O3Purity:99.72% - 99.97%Color and Shape:SolidMolecular weight:318.45SW044248
CAS:<p>SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.</p>Formula:C22H23N5O2SPurity:99.56% - 99.87%Color and Shape:SolidMolecular weight:421.52CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Formula:C28H38N4O3Purity:97.83%Color and Shape:SolidMolecular weight:478.63LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Formula:C24H15F3N4OPurity:98.31% - 99.32%Color and Shape:SolidMolecular weight:432.4Cardioxane
CAS:<p>Cardioxane (ADR-529) is a cardio-protective drug.</p>Formula:C11H16N4O4·HClPurity:98.08%Color and Shape:SolidMolecular weight:304.73Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formula:C8H12N5O4PPurity:99.56%Color and Shape:White To Off-White PowderMolecular weight:273.19PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8SRT 2104
CAS:<p>SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.</p>Formula:C26H24N6O2S2Purity:98.34% - 99.82%Color and Shape:SolidMolecular weight:516.64Leniolisib
CAS:<p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>Formula:C21H25F3N6O2Purity:99.88%Color and Shape:SolidMolecular weight:450.46
