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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Nucleoside antimetabolites and analogs are compounds that mimic natural nucleosides and are incorporated into DNA during replication, leading to chain termination or the inhibition of DNA synthesis. These compounds are widely used as chemotherapeutic agents in the treatment of cancer and viral infections. By disrupting DNA synthesis, nucleoside analogs induce cell cycle arrest and apoptosis. At CymitQuimica, we provide a wide range of high-quality nucleoside antimetabolites and analogs to support your research in cancer treatment, antiviral therapy, and DNA replication.

Found 1388 products of "Nucleoside Antimetabolite/Analog"

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  • Cytidine

    CAS:
    <p>Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond.</p>
    Formula:C9H13N3O5
    Purity:98.80% - 99.63%
    Color and Shape:Physical Description White Crystalline Powder (Ntp 1992)
    Molecular weight:243.22
  • Floxuridine

    CAS:
    <p>Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.</p>
    Formula:C9H11FN2O5
    Purity:98.92% - 99.96%
    Color and Shape:Solid
    Molecular weight:246.19
  • Adenosine

    CAS:
    <p>Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.</p>
    Formula:C10H13N5O4
    Purity:98.76% - 99.86%
    Color and Shape:Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)
    Molecular weight:267.24
  • 6-Mercaptopurine

    CAS:
    <p>6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.</p>
    Formula:C5H4N4S
    Purity:99.53% - 99.63%
    Color and Shape:Yellow Crystalline Powder Solid
    Molecular weight:152.18
  • Cytarabine

    CAS:
    <p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>
    Formula:C9H13N3O5
    Purity:99.83% - 99.93%
    Color and Shape:Fine Off-White Crystalline Powder
    Molecular weight:243.22
  • Trifluridine

    CAS:
    <p>Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.</p>
    Formula:C10H11F3N2O5
    Purity:99.39% - 99.82%
    Color and Shape:White Crystalline Powder
    Molecular weight:296.2
  • 5-Azacytidine

    CAS:
    <p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>
    Formula:C8H12N4O5
    Purity:99.31% - 99.79%
    Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)
    Molecular weight:244.2
  • Gemcitabine

    CAS:
    <p>Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>
    Formula:C9H11F2N3O4
    Purity:98.66% - 99.67%
    Color and Shape:Solid
    Molecular weight:263.2
  • 5-Fluorouracil

    CAS:
    <p>5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.</p>
    Formula:C4H3FN2O2
    Purity:98% - >99.99%
    Color and Shape:White To Practically White Crystalline Powder Neoplastic Drug Chemosterilant For Insects (Epa 1998)
    Molecular weight:130.08
  • Decitabine

    CAS:
    <p>Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.</p>
    Formula:C8H12N4O4
    Purity:98.06% - 99.87%
    Color and Shape:Physical Description Fine White Crystalline Powder Used As A Drug
    Molecular weight:228.21
  • SIBA

    CAS:
    <p>SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.</p>
    Formula:C14H21N5O3S
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:339.41
  • Orotic acid

    CAS:
    <p>Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.</p>
    Formula:C5H4N2O4
    Purity:99.42%
    Color and Shape:Crystals Physical Description White Crystals Or Crystalline Powder (Ntp 1992)
    Molecular weight:156.1
  • Dacarbazine

    CAS:
    <p>Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.</p>
    Formula:C6H10N6O
    Purity:99.78% - 99.87%
    Color and Shape:Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)
    Molecular weight:182.18
  • Tegafur

    CAS:
    <p>Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.</p>
    Formula:C8H9FN2O3
    Purity:99.16% - 99.89%
    Color and Shape:White Crystalline Powder
    Molecular weight:200.17
  • Carmofur

    CAS:
    <p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>
    Formula:C11H16FN3O3
    Purity:98.53% - 99.98%
    Color and Shape:Solid
    Molecular weight:257.26
  • Clofarabine

    CAS:
    <p>Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide</p>
    Formula:C10H11ClFN5O3
    Purity:99.94% - >99.99%
    Color and Shape:White Solid
    Molecular weight:303.68
  • Doxifluridine

    CAS:
    <p>Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.</p>
    Formula:C9H11FN2O5
    Purity:99.47% - 99.86%
    Color and Shape:White Solid
    Molecular weight:246.19
  • Fludarabine

    CAS:
    <p>Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.</p>
    Formula:C10H12FN5O4
    Purity:99.65% - 99.89%
    Color and Shape:White Solid
    Molecular weight:285.23
  • Capecitabine

    CAS:
    <p>Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.</p>
    Formula:C15H22FN3O6
    Purity:99.81% - >99.99%
    Color and Shape:Less Solid Colourless Solid
    Molecular weight:359.35
  • Vidarabine

    CAS:
    <p>Vidarabine is a nucleoside antibiotic from Streptomyces with antiviral properties, effective against herpes and other DNA viruses.</p>
    Formula:C10H13N5O4
    Purity:99.85%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:267.24
  • Stavudine

    CAS:
    <p>Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.</p>
    Formula:C10H12N2O4
    Purity:99.01% - 99.88%
    Color and Shape:White Powder
    Molecular weight:224.21
  • Ganciclovir

    CAS:
    <p>Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.</p>
    Formula:C9H13N5O4
    Purity:99.55% - 99.58%
    Color and Shape:White Powder
    Molecular weight:255.23
  • m7GpppGpG

    CAS:
    <p>m7GpppGpG, a trinucleotide cap, protects mRNA from 5′ exonucleases &amp; aids splicing and translation.</p>
    Formula:C31H41N15O25P4
    Color and Shape:Solid
    Molecular weight:1147.64
  • 6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity by</p>
    Formula:C15H17N5O6
    Color and Shape:Solid
    Molecular weight:363.33
  • 2'-O-Methyladenosine 5'-monophosphate triethyl ammonium


    <p>2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.</p>
    Formula:C11H14N5O7P2
    Color and Shape:Solid
    Molecular weight:359.23
  • 2'-β-C-Methyl-3-deazauri dine

    CAS:
    <p>2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies.</p>
    Formula:C11H15NO6
    Color and Shape:Solid
    Molecular weight:257.24
  • Rev 2'-O-MOE-5MeC(Bz)-5'-amidite


    <p>Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C50H60N5O10P
    Color and Shape:Solid
    Molecular weight:922.01
  • 2-Diethoxymethyl adenosine


    <p>2-Diethoxymethyl adenosine, an adenosine analog, dilates smooth muscle, inhibits cancer, and leads to drugs like Acadesine.</p>
    Formula:C23H31N5O10
    Color and Shape:Solid
    Molecular weight:537.52
  • 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite


    <p>5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.</p>
    Formula:C44H49F2N4O7P
    Color and Shape:Solid
    Molecular weight:814.85
  • 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical and</p>
    Formula:C10H17N7O3
    Color and Shape:Solid
    Molecular weight:283.29
  • 5'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine


    <p>5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent</p>
    Formula:C25H24N2O8
    Color and Shape:Solid
    Molecular weight:480.47
  • N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine


    <p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H22N2O7
    Color and Shape:Solid
    Molecular weight:330.33
  • N7-Methyl-2'-O-(2-methoxyethyl) guanosine


    <p>N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H21N5O6
    Color and Shape:Solid
    Molecular weight:355.35
  • TLR7 agonist 12

    CAS:
    <p>TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Formula:C14H19N5O8
    Color and Shape:Solid
    Molecular weight:385.33
  • N4-(3,3,3-Trifluoropropanoyl)cytidine


    <p>N4-(3,3,3-Trifluoropropanoyl)cytidine, a cytidine analog, inhibits DNA methyltransferases, possibly anti-metabolic and anti-cancer.</p>
    Formula:C12H14F3N3O6
    Color and Shape:Solid
    Molecular weight:353.25
  • 1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine


    <p>1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.</p>
    Formula:C18H18F3N5O4
    Color and Shape:Solid
    Molecular weight:425.36
  • N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine


    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Formula:C41H43N3O9
    Color and Shape:Solid
    Molecular weight:721.79
  • 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine


    <p>2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C21H35FN2O5
    Color and Shape:Solid
    Molecular weight:414.51
  • 5'(R)-C-Methyl-5-fluorouridine


    <p>5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.</p>
    Formula:C10H13FN2O6
    Color and Shape:Solid
    Molecular weight:276.22
  • Adenosine Dialdehyde (ADOX)

    CAS:
    <p>Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.</p>
    Formula:C10H11N5O4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:265.23
  • N3-[(Pyrid-4-yl)methyl]uridine


    <p>N3-[(Pyrid-4-yl)methyl]uridine, a uridine analog, may have antiepileptic properties and aid in researching anticonvulsants and anxiolytics.</p>
    Formula:C15H17N3O6
    Color and Shape:Solid
    Molecular weight:335.31
  • 1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine


    <p>1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.</p>
    Formula:C15H21N5O4
    Color and Shape:Solid
    Molecular weight:335.36
  • 2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium


    <p>2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits broad antitumor activity specifically targeting indolent</p>
    Formula:C22H43FN7O7P
    Color and Shape:Solid
    Molecular weight:567.59
  • N1-(2-Methyl)propyl pseudouridine


    <p>N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.</p>
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.31
  • Flurocitabine HCl

    CAS:
    <p>Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.</p>
    Formula:C9H11ClFN3O4
    Purity:98.45% - 99.23%
    Color and Shape:Soild
    Molecular weight:279.65
  • 3'-β-C-Methyl-2-thiouridine


    <p>3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C10H14N2O5S
    Color and Shape:Solid
    Molecular weight:274.29
  • 5-Aza-xylo-cytidine


    <p>5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Formula:C8H12N4O5
    Color and Shape:Solid
    Molecular weight:244.2
  • UnyLinker 12 TEA


    <p>UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.</p>
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655
  • Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C4H5N3O
    Color and Shape:White To Off-White Solid
    Molecular weight:111.1
  • 6-Thioguanosine

    CAS:
    <p>6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.</p>
    Formula:C10H13N5O4S
    Purity:97.05%
    Color and Shape:Yellow-Green Powder
    Molecular weight:299.31