Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(940 products)
- ACK(1 products)
- AChR(574 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,939 products)
- BACE(36 products)
- Beta Amyloid(204 products)
- CaMK(68 products)
- Cyclooxygenase (COX) Inhibitors(562 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(296 products)
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Found 5400 products of "Neuroscience"
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NAS-181
CAS:<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formula:C20H30N2O7SColor and Shape:SolidMolecular weight:442.53BACE1-IN-10
CAS:<p>BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].</p>Formula:C33H49N5O8SPurity:98%Color and Shape:SolidMolecular weight:675.84CAY10649
CAS:<p>1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.</p>Formula:C17H12ClNO2SColor and Shape:SolidMolecular weight:329.8P2X3-IN-1
CAS:<p>P2X3-IN-1 (example 7) is a P2X3 receptor inhibitor suitable for research on neurogenic diseases [1].</p>Formula:C22H21FN8O3Purity:98%Color and Shape:SolidMolecular weight:464.45Gepirone
CAS:<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47MAO-B-IN-1
CAS:<p>MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.</p>Formula:C16H14F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:369.36L-822179
CAS:<p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>Formula:C17H14N8O2Purity:98.5% - 99.61%Color and Shape:SolidMolecular weight:362.35Brasofensine Maleate
CAS:<p>Brasofensine Maleate inhibits the monoamine re-uptake.</p>Formula:C20H24Cl2N2O5Color and Shape:SolidMolecular weight:443.32Bisnorcymserine
CAS:<p>Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).</p>Formula:C21H25N3O2Purity:98%Color and Shape:SolidMolecular weight:351.44GYKI-46903 HCl
CAS:<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Formula:C17H21ClFNO2Color and Shape:SolidMolecular weight:325.81MK-8768
CAS:<p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>Formula:C21H22F3N5O2Color and Shape:SolidMolecular weight:433.43BACE1-IN-1
CAS:<p>BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).</p>Formula:C18H14F3N5O2Purity:98%Color and Shape:SolidMolecular weight:389.33AChE-IN-30
CAS:<p>AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Formula:C16H23N5Purity:99.62%Color and Shape:SolidMolecular weight:285.39L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Formula:C11H15N3OColor and Shape:SolidMolecular weight:205.26Brasofensine
CAS:<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formula:C16H20Cl2N2OColor and Shape:SolidMolecular weight:327.25LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Formula:C28H38N2O2Color and Shape:SolidMolecular weight:434.61ELND007
CAS:<p>ELND007 is a Gamma secretase inhibitor.</p>Formula:C19H14F4N4O2SColor and Shape:SolidMolecular weight:438.4mGluR5 antagonist-1
CAS:<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Formula:C23H18N4O2Color and Shape:SolidMolecular weight:382.41R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formula:C22H30ClNO3Color and Shape:SolidMolecular weight:391.93Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Formula:C18H23FN2O2Purity:98%Color and Shape:SolidMolecular weight:318.39SCS
CAS:<p>SCS is a GABAA receptor antagonist.</p>Formula:C14H12N2O3Purity:99.73%Color and Shape:SolidMolecular weight:256.26BMT-124110
CAS:<p>BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.</p>Formula:C21H27N3O3Purity:98.07%Color and Shape:SolidMolecular weight:369.46Eslicarbazepine
CAS:<p>Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.</p>Formula:C15H14N2O2Purity:99.97%Color and Shape:Off-White SolidMolecular weight:254.28Nemonapride
CAS:<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Formula:C4H10NO5PPurity:98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:183.1VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formula:C18H20N6O3S2Purity:98.09% - 98.1%Color and Shape:SolidMolecular weight:432.52P2X3 antagonist 38
CAS:<p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>Formula:C22H25F3N6O3Purity:98%Color and Shape:SolidMolecular weight:478.47Fosthiazate
CAS:<p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>Formula:C9H18NO3PS2Purity:97.78%Color and Shape:SolidMolecular weight:283.35NP-1815-PX
CAS:<p>NP-1815-PX is a P2X4R antagonist with anti-inflammatory and analgesic properties, inhibiting guinea pig tracheal, and can be used in chronic pain research.</p>Formula:C21H13N4NaO3SPurity:97.82% - 99.39%Color and Shape:SolidMolecular weight:424.41cis-PDA
CAS:<p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>Formula:C7H11NO4Purity:98.71%Color and Shape:White SolidMolecular weight:173.17NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Formula:C21H34N2O10S2Purity:98%Color and Shape:SolidMolecular weight:538.63GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42Mesembrine
CAS:<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Formula:C17H23NO3Color and Shape:SolidMolecular weight:289.37L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Formula:C17H16ClN5O2Purity:98%Color and Shape:SolidMolecular weight:357.79Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.725-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C22H27N5OPurity:98%Color and Shape:SolidMolecular weight:377.48Abaperidone
CAS:<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Formula:C25H25FN2O5Purity:98.22%Color and Shape:SolidMolecular weight:452.47AChE-IN-31
CAS:<p>AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].</p>Formula:C27H44Na2O9S2Color and Shape:SolidMolecular weight:622.74FPPQ
CAS:<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Formula:C21H19FN4O2SColor and Shape:SolidMolecular weight:410.46PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Formula:C27H30N4O2S2Purity:98%Color and Shape:SolidMolecular weight:506.68AAK1-IN-5
CAS:<p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>Formula:C19H23F4N3OColor and Shape:SolidMolecular weight:385.4LY3202626
CAS:<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Formula:C22H20F2N8O2SPurity:98%Color and Shape:SolidMolecular weight:498.51AAK1-IN-2
CAS:<p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.</p>Formula:C20H20N4Color and Shape:SolidMolecular weight:316.4MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Formula:C25H26Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:538.85UNC9994 hydrochloride
CAS:<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Formula:C21H23Cl3N2OSColor and Shape:SolidMolecular weight:457.84Velusetrag
CAS:<p>Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.</p>Formula:C25H36N4O5SColor and Shape:SolidMolecular weight:504.64KBR 2822
CAS:<p>KBR 2822 is an inhibitor of esterase.</p>Formula:C9H15ClF3O3PSPurity:98%Color and Shape:SolidMolecular weight:326.7Pomaglumetad methionil hydrochloride
CAS:<p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>Formula:C12H19ClN2O7S2Purity:98.57%Color and Shape:SolidMolecular weight:402.87CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76Quinolactacin A1
CAS:<p>Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.</p>Formula:C16H18N2O2Color and Shape:SolidMolecular weight:270.33ADX71441
CAS:<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Formula:C19H15ClF2N4O4Color and Shape:SolidMolecular weight:436.8Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Formula:C18H18FN7Color and Shape:SolidMolecular weight:351.38VU6005649
CAS:<p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>Formula:C16H12F5N3OPurity:99.87%Color and Shape:SolidMolecular weight:357.28VU0029251
CAS:<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Formula:C10H11N3S2Color and Shape:SolidMolecular weight:237.34AAK1-IN-3
CAS:<p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>Formula:C20H20N4Color and Shape:SolidMolecular weight:316.4Cimicoxib
CAS:<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Formula:C16H13ClFN3O3SPurity:98.22%Color and Shape:SolidMolecular weight:381.81Diproqualone
CAS:<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Formula:C12H14N2O3Color and Shape:SolidMolecular weight:234.255A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Formula:C14H15N3Purity:98%Color and Shape:SolidMolecular weight:225.29AChE-IN-19
CAS:<p>AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.</p>Formula:C30H33NO7Color and Shape:SolidMolecular weight:519.59Lanabecestat camsylate
CAS:<p>Lanabecestat camsylate is used as a BACE1 Inhibitor.</p>Formula:C36H44N4O5SPurity:98%Color and Shape:SolidMolecular weight:644.83PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Formula:C14H21N3O4S2Purity:98%Color and Shape:SolidMolecular weight:359.46Naspm trihydrochloride
CAS:<p>Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA</p>Formula:C22H37Cl3N4OPurity:99.75%Color and Shape:SolidMolecular weight:479.91Nevadistinel
CAS:<p>Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits</p>Formula:C15H18N2O3Purity:98%Color and Shape:SolidMolecular weight:274.325-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Formula:C14H20N2OPurity:98%Color and Shape:SolidMolecular weight:232.32Cyclophostin
CAS:<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Formula:C8H11O6PPurity:98%Color and Shape:SolidMolecular weight:234.14LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Formula:C21H26N4O3Purity:98%Color and Shape:SolidMolecular weight:382.46NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Formula:C13H13NaO3Purity:98%Color and Shape:SolidMolecular weight:240.23Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Formula:C16H21N3O2C4H4O4Color and Shape:SolidMolecular weight:345.4Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Formula:C16H27NO5SColor and Shape:SolidMolecular weight:345.45mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Formula:C28H34ClN3O2S2Color and Shape:SolidMolecular weight:544.17Afizagabar
CAS:<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Formula:C19H12FN3O2SColor and Shape:SolidMolecular weight:365.38Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formula:C14H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:267.75JNJ-46281222
CAS:<p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>Formula:C23H25F3N4Color and Shape:SolidMolecular weight:414.47LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Formula:C21H28N2O3Purity:98%Color and Shape:SolidMolecular weight:356.46BMS-983970
CAS:<p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>Formula:C26H26F4N4O3Color and Shape:SolidMolecular weight:518.5SB 258719
CAS:<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Formula:C18H30N2O2SPurity:99.73%Color and Shape:SolidMolecular weight:338.51AChE-IN-44
CAS:<p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>Formula:C31H38ClN3OS2Color and Shape:SolidMolecular weight:568.24PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formula:C18H15N3O3Purity:99.79%Color and Shape:SolidMolecular weight:321.33MTPG
CAS:<p>Group II/group III metabotropic glutamate receptor antagonist</p>Formula:C10H11N5O2Purity:98%Color and Shape:SolidMolecular weight:233.23YM348
CAS:<p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.3ASS234
CAS:<p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>Formula:C29H37N3OColor and Shape:SolidMolecular weight:443.62FPTQ
CAS:<p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>Formula:C17H12FN5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:305.31DQP-26
CAS:<p>DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,</p>Formula:C28H21Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:534.39(1α,1'S,4β)-Lanabecestat
CAS:<p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>Formula:C26H28N4OColor and Shape:SolidMolecular weight:412.53mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Formula:C19H22N2O2Color and Shape:SolidMolecular weight:310.39PQM130
CAS:<p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>Formula:C23H27NO4Purity:98.73%Color and Shape:SolidMolecular weight:381.46BACE1-IN-13
CAS:<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Formula:C20H17FN8O2Purity:98%Color and Shape:SolidMolecular weight:420.43-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Formula:C11H13BrN2OPurity:99.974%Color and Shape:SolidMolecular weight:269.14MAO-B-IN-19
CAS:<p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>Formula:C15H11FO2Purity:98%Color and Shape:SolidMolecular weight:242.25(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Formula:C15H19F2N3OPurity:98%Color and Shape:SolidMolecular weight:295.33Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formula:C14H17N3OColor and Shape:SolidMolecular weight:243.3Pregnanolone sulfate (pyridinium)
CAS:<p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>Formula:C26H39NO5SPurity:98%Color and Shape:SolidMolecular weight:477.66Yhhu-3792 hydrochloride
CAS:<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Formula:C24H25ClN4O2Color and Shape:SolidMolecular weight:436.93DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Formula:C23H26ClN3O5SColor and Shape:SolidMolecular weight:491.99NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Formula:C18H24ClFN2O2Purity:98%Color and Shape:SolidMolecular weight:354.85(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Formula:C18H20ClN3OPurity:98%Color and Shape:SolidMolecular weight:329.82β-Secretase Inhibitor IV
CAS:<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Formula:C31H38N4O5SPurity:98%Color and Shape:SolidMolecular weight:578.72BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Formula:C16H19N7OPurity:98%Color and Shape:SolidMolecular weight:325.37
