Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,018 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5514 products of "Neuroscience"
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LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formula:C24H26N6OPurity:99.26%Color and Shape:SolidMolecular weight:414.5BL-1020 Mesylate
CAS:BL-1020 Mesylate (CYP-1020 Mesylate) is a GABA A receptor agonist and D2 antagonist used in studies of neurodegeneration.Formula:C28H45ClN4O11S4Purity:>99.99%Color and Shape:SolidMolecular weight:777.39Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Formula:C22H22ClFN2OPurity:96%Color and Shape:SolidMolecular weight:384.87Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:98.77% - 99.67%Color and Shape:SolidMolecular weight:233.35Ensaculin
CAS:Ensaculin, a benzopyrone-piperazine compound, enhances memory, protects neurons, and may treat dementia.Formula:C26H32N2O5Purity:99.56% - 99.81%Color and Shape:SolidMolecular weight:452.54Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89DMCM hydrochloride
CAS:DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.Formula:C17H19ClN2O4Purity:99.56%Color and Shape:SolidMolecular weight:350.8Ref: TM-T11061
1mg34.00€2mg50.00€5mg80.00€10mg105.00€25mg236.00€50mg439.00€100mg620.00€1mL*10mM (DMSO)88.00€Alpidem
CAS:Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.Formula:C21H23Cl2N3OPurity:99.56% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:404.33Ref: TM-T26600
1mg58.00€5mg137.00€10mg207.00€25mg371.00€50mg522.00€100mg747.00€500mg1,513.00€1mL*10mM (DMSO)122.00€Lenumlostat
CAS:Lenumlostat is a lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.Formula:C18H17F4N3O3Purity:99.11%Color and Shape:SolidMolecular weight:399.34Ref: TM-T69913
1mg177.00€5mg447.00€10mg672.00€25mg1,341.00€50mg2,088.00€100mg2,988.00€500mg6,004.00€1mL*10mM (DMSO)492.00€AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Formula:C14H6F2N4OPurity:98.29%Color and Shape:SolidMolecular weight:284.22Muscimol HBr
CAS:Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.Formula:C4H7BrN2O2Purity:98.13%Color and Shape:Off-White PowderMolecular weight:195.01Ref: TM-T20657
1mg113.00€2mg169.00€5mg240.00€10mg385.00€25mg622.00€50mg898.00€100mg1,198.00€500mg2,422.00€1mL*10mM (DMSO)205.00€Lirequinil
CAS:Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Formula:C26H25ClN2O3Purity:98.54%Color and Shape:SolidMolecular weight:448.94Liafensine
CAS:Liafensine(BMS-820836): Selective inhibitor for serotonin, norepinephrine, dopamine reuptake; targets major depression, CNS disorders.Formula:C24H22N4Purity:99.91%Color and Shape:SolidMolecular weight:366.46Aceclidine
CAS:Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocularFormula:C9H15NO2Purity:>99.99%Color and Shape:SolidMolecular weight:169.22DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99.91% - 99.99%Color and Shape:SolidMolecular weight:443.37R 59-022 hydrochloride
CAS:R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C27H27ClFN3OSPurity:97.7%Color and Shape:SolidMolecular weight:496.04Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Formula:C16H25N3O5SPurity:99.1%Color and Shape:SolidMolecular weight:371.45Ref: TM-T13353
5mg35.00€10mg55.00€25mg100.00€50mg159.00€100mg245.00€200mg353.00€1mL*10mM (DMSO)39.00€Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Formula:C18H19FN2O3SPurity:97.61% - 99.99%Color and Shape:SolidMolecular weight:362.42Masupirdine free base
CAS:Masupirdine free base (SUVN-502 free base) is a 5-HT6 receptor antagonist that can be used to study neurological disorders like Alzheimer's disease.Formula:C21H24BrN3O3SPurity:98.36% - 99.65%Color and Shape:SolidMolecular weight:478.4SCH-900271
CAS:SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.Formula:C14H16N2O4Purity:98.82% - 99.93%Color and Shape:SolidMolecular weight:276.29Ref: TM-T34573
1mg112.00€5mg261.00€10mg396.00€25mg655.00€50mg888.00€100mg1,251.00€500mg2,493.00€1mL*10mM (DMSO)249.00€Femoxetine hydrochloride
CAS:Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.Formula:C20H26ClNO2Purity:99.63%Color and Shape:SolidMolecular weight:347.888-OH-Dpat
CAS:8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.Formula:C16H25NOPurity:98%Color and Shape:SolidMolecular weight:247.38Tribendimidine
CAS:Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.Formula:C28H32N6Purity:≥98%Color and Shape:SolidMolecular weight:452.59Tedatioxetine
CAS:Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Formula:C18H21NSPurity:99.76% - >99.99%Color and Shape:SolidMolecular weight:283.43CP 96021
CAS:"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."
Formula:C29H21FN4OSPurity:97.81% - 99.62%Color and Shape:SoildMolecular weight:492.57Adoprazine
CAS:Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
Formula:C24H24FN3O2Purity:99.83%Color and Shape:SolidMolecular weight:405.46AZD6538
CAS:AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.Formula:C15H6FN5OPurity:98.68%Color and Shape:SolidMolecular weight:291.24Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFormula:C24H27FN4O2Purity:97.86%Color and Shape:SolidMolecular weight:422.5Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Formula:C16H19NOPurity:99.68%Color and Shape:SolidMolecular weight:241.33Ref: TM-T67956
1mg92.00€5mg207.00€10mg309.00€25mg527.00€50mg755.00€100mg1,044.00€500mg2,088.00€1mL*10mM (DMSO)178.00€Roxindole
CAS:Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.Formula:C23H26N2OPurity:98.03% - 98.93%Color and Shape:SolidMolecular weight:346.47McN-A 343
CAS:McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.Formula:C14H18Cl2N2O2Purity:99.65%Color and Shape:SolidMolecular weight:317.21cis-Urocanic acid
CAS:cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM).Formula:C6H6N2O2Purity:99.81%Color and Shape:SolidMolecular weight:138.125-HT6/7 antagonist 1
CAS:5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
Formula:C22H20FN3O3Purity:98.78% - 99.26%Color and Shape:SolidMolecular weight:393.41VU 0285683
CAS:VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.Formula:C14H7FN4OPurity:99.98%Color and Shape:SolidMolecular weight:266.23Ref: TM-T23509
2mg42.00€5mg64.00€10mg79.00€25mg118.00€50mg170.00€100mg235.00€200mg319.00€1mL*10mM (DMSO)71.00€Ecopipam
CAS:Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.Formula:C19H20ClNOPurity:99.68%Color and Shape:SolidMolecular weight:313.82Golexanolone
CAS:Golexanolone can be used to study neurological diseases.Formula:C21H31NO2Purity:99.90% - 99.99%Color and Shape:SolidMolecular weight:329.48PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purity:95.16% - 98.16%Color and Shape:SolidMolecular weight:650.85Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurity:99.88%Color and Shape:SolidMolecular weight:425.52Ref: TM-T15270
2mg39.00€5mg52.00€10mg77.00€25mg110.00€50mg166.00€100mg236.00€200mg349.00€1mL*10mM (DMSO)58.00€LY-2624803
CAS:LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.Formula:C22H25N3O3Purity:99.78% - 99.97%Color and Shape:SolidMolecular weight:379.45(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Formula:C14H13NPurity:99.96%Color and Shape:SolidMolecular weight:195.26Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurity:99.1%Color and Shape:SoildMolecular weight:483.77PNU109291
CAS:PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.Formula:C24H31N3O3Purity:98%Color and Shape:SolidMolecular weight:409.52Flesinoxan HCl
CAS:Flesinoxan HCl is the salt form of Flesinoxan, which is a selective 5-HT1A receptor agonist.Formula:C22H27ClFN3O4Color and Shape:SolidMolecular weight:451.92CP-409092
CAS:CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.Formula:C17H19N3O2Purity:98%Color and Shape:SolidMolecular weight:297.35Tolterodine Dimer
CAS:Tolterodine Dimer is a derivative of Tolterodine -- a muscarinic receptor antagonist that is used to treat patients with overactive bladder.Formula:C35H41NO2Color and Shape:SolidMolecular weight:507.71BMT-124110
CAS:BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.Formula:C21H27N3O3Purity:98.07%Color and Shape:SolidMolecular weight:369.46SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Formula:C18H30N2O2SPurity:99.73%Color and Shape:SolidMolecular weight:338.51Ref: TM-T12855
2mg34.00€5mg52.00€10mg85.00€25mg155.00€50mg240.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)58.00€(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formula:C4H9NO3Color and Shape:SolidMolecular weight:119.12VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Formula:C18H20N6O3S2Purity:98.09% - 98.1%Color and Shape:SolidMolecular weight:432.52SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formula:C25H28N4O5SColor and Shape:SolidMolecular weight:496.58CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formula:C18H22Cl2NO3PColor and Shape:SolidMolecular weight:402.25Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFormula:C9H18NO3PS2Purity:97.78%Color and Shape:SolidMolecular weight:283.35Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47L-822179
CAS:L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Formula:C17H14N8O2Purity:98.5% - 99.61%Color and Shape:SolidMolecular weight:362.35Org-21465
CAS:Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Formula:C27H43NO4Purity:98%Color and Shape:SolidMolecular weight:445.63ASP8302
CAS:ASP8302 is an allosteric potentiator of the muscarinic M3 receptor. It enhances urination efficiency and reduces residual urine volume in two rat models of voiding dysfunction. ASP8302 is useful for investigating diseases associated with bladder dysfunction.Formula:C26H32ClN7O3S2Color and Shape:SolidMolecular weight:590.16Serine Hydrolase inhibitor-21
CAS:Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for AlzheimerFormula:C18H12N2O2SPurity:98%Color and Shape:SolidMolecular weight:320.37Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Formula:C13H13N3OColor and Shape:SolidMolecular weight:227.267Lanabecestat HCl
CAS:Lanabecestat (AZD3293/LY3314814) is a potent oral BACE1 inhibitor that crosses the BBB and reduces Aβ levels.Formula:C26H29ClN4OColor and Shape:SolidMolecular weight:448.995Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Formula:C21H27NColor and Shape:SolidMolecular weight:293.45GABA-IN-2
CAS:GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Formula:C12H4Cl2F6N4SeColor and Shape:SolidMolecular weight:468.04RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Formula:C22H27NO2S2Purity:98%Color and Shape:SolidMolecular weight:401.59TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Formula:C20H22FN7OPurity:99.75%Color and Shape:SolidMolecular weight:395.43Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purity:99.88%Color and Shape:SolidMolecular weight:531.6Ref: TM-T13385
2mg34.00€5mg50.00€10mg75.00€25mg128.00€50mg200.00€100mg304.00€200mg424.00€1mL*10mM (DMSO)58.00€A-424274
CAS:A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.Formula:C14H15N3Purity:98%Color and Shape:SolidMolecular weight:225.29Capeserod HCl
CAS:Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.Formula:C23H26Cl2N4O4Purity:98%Color and Shape:SolidMolecular weight:493.38LY 53857
CAS:LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.Formula:C27H36N2O7Color and Shape:SolidMolecular weight:500.592PHP 501 trifluoroacetate
CAS:GABAA antagonistFormula:C20H21N3OPurity:98%Color and Shape:SolidMolecular weight:319.4FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Formula:C16H19N7OPurity:98%Color and Shape:SolidMolecular weight:325.37KBR 2822
CAS:KBR 2822 is an inhibitor of esterase.Formula:C9H15ClF3O3PSPurity:98%Color and Shape:SolidMolecular weight:326.7LG 50643
CAS:LG 50643 is a muscarinic antagonist.Formula:C24H34INO2Purity:98%Color and Shape:SolidMolecular weight:495.44GMA-839
CAS:GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.Formula:C21H31F3O3Purity:98%Color and Shape:SolidMolecular weight:388.46VU6005649
CAS:VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).Formula:C16H12F5N3OPurity:99.87%Color and Shape:SolidMolecular weight:357.28Octahydroaminoacridine succinate
CAS:Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.Formula:C17H24N2O4Purity:99.91%Color and Shape:SolidMolecular weight:320.38PZ-II-029
CAS:PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.Formula:C18H15N3O3Purity:99.79%Color and Shape:SolidMolecular weight:321.33Ref: TM-T28479
1mg50.00€5mg105.00€10mg167.00€25mg289.00€50mg447.00€100mg685.00€500mg1,378.00€1mL*10mM (DMSO)192.00€Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Formula:C30H30O4Purity:98%Color and Shape:SolidMolecular weight:454.56Brasofensine Maleate
CAS:Brasofensine Maleate inhibits the monoamine re-uptake.Formula:C20H24Cl2N2O5Color and Shape:SolidMolecular weight:443.32Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purity:96.89%Color and Shape:SolidMolecular weight:244.2Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Formula:C15H19ClN4OPurity:98.70%Color and Shape:SolidMolecular weight:306.79(+)-Bicuculline methiodide
CAS:(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Formula:C21H20INO6Purity:99.24%Color and Shape:SolidMolecular weight:509.29(±)-Fabesetron hydrochloride
CAS:FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Formula:C18H20ClN3OPurity:98%Color and Shape:SolidMolecular weight:329.82Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFormula:C25H25Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:502.39YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.3VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Formula:C21H19F3N4O4Purity:99.61% - 99.74%Color and Shape:SolidMolecular weight:448.4Ref: TM-T13323
1mg34.00€2mg49.00€5mg74.00€10mg119.00€25mg225.00€50mg404.00€100mg592.00€1mL*10mM (DMSO)82.00€JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Formula:C23H25F3N4Color and Shape:SolidMolecular weight:414.47Lanabecestat
CAS:Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.Formula:C26H28N4OPurity:98.55%Color and Shape:SolidMolecular weight:412.53Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFormula:C23H22N4O3Color and Shape:SolidMolecular weight:402.45COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.75%Color and Shape:SolidMolecular weight:337.82Ref: TM-T36520
1mg38.00€5mg86.00€10mg123.00€25mg215.00€50mg299.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)94.00€VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Formula:C10H11N3S2Color and Shape:SolidMolecular weight:237.34AAK1-IN-4
CAS:AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Formula:C20H28N4O3Color and Shape:SolidMolecular weight:372.46AAK1-IN-5
CAS:AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.Formula:C19H23F4N3OColor and Shape:SolidMolecular weight:385.4Quinolactacin A1
CAS:Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.Formula:C16H18N2O2Color and Shape:SolidMolecular weight:270.33MAO-B-IN-13
CAS:MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).Formula:C18H19NO3Color and Shape:SolidMolecular weight:297.35AChE-IN-30
CAS:AChE-IN-30 is an acetylcholinesterase inhibitor (IC50 4.4 μM) that reduces oxidative stress and apoptosis, useful for Alzheimer’s disease research models.Formula:C22H24N4O2Purity:99.96%Color and Shape:SolidMolecular weight:376.45AAK1-IN-2
CAS:AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.Formula:C20H20N4Color and Shape:SolidMolecular weight:316.4Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Formula:C12H19ClN2O7S2Purity:98.57%Color and Shape:SolidMolecular weight:402.87Diproqualone
CAS:Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Formula:C12H14N2O3Color and Shape:SolidMolecular weight:234.255Velusetrag
CAS:Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Formula:C25H36N4O5SColor and Shape:SolidMolecular weight:504.64P11149
CAS:P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.Formula:C27H34ClNO4Color and Shape:SolidMolecular weight:472.02
